{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T09:11:47Z","timestamp":1780477907066,"version":"3.54.1"},"reference-count":48,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hand Clinics"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.hcl.2024.07.006","type":"journal-article","created":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T17:29:29Z","timestamp":1725298169000},"page":"57-64","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Role of Synovectomy in Rheumatoid Hand and Wrist"],"prefix":"10.1016","volume":"41","author":[{"given":"Jamie A.","family":"Mawhinney","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerstin","family":"Oestreich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommy","family":"Lindau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.hcl.2024.07.006_bib1","doi-asserted-by":"crossref","first-page":"741","DOI":"10.2106\/00004623-196547040-00008","article-title":"Surgical treatment at the wrist in rheumatoid arthritis: a review of thirty-seven patients","volume":"47","author":"Clayton","year":"1965","journal-title":"J\u00a0Bone Joint Surg Am"},{"issue":"3","key":"10.1016\/j.hcl.2024.07.006_bib2","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/S0030-5898(20)30988-3","article-title":"Preventive surgery - tenosynovectomy and synovectomy","volume":"6","author":"Millender","year":"1975","journal-title":"Orthop Clin North Am"},{"issue":"10055","key":"10.1016\/j.hcl.2024.07.006_bib3","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1016\/S0140-6736(16)30173-8","article-title":"Rheumatoid arthritis","volume":"388","author":"Smolen","year":"2016","journal-title":"Lancet (London, England)"},{"issue":"Suppl 1","key":"10.1016\/j.hcl.2024.07.006_bib4","doi-asserted-by":"crossref","first-page":"S18","DOI":"10.1016\/S0720-048X(98)00038-2","article-title":"The clinical features of rheumatoid arthritis","volume":"27","author":"Grassi","year":"1998","journal-title":"Eur J Radiol"},{"issue":"4","key":"10.1016\/j.hcl.2024.07.006_bib5","first-page":"192","article-title":"Rheumatoid hand surgery in the era of biologic therapy: a rheumatologist-oriented overview","volume":"28","author":"Park","year":"2021","journal-title":"J\u00a0Rheum Dis"},{"issue":"3","key":"10.1016\/j.hcl.2024.07.006_bib6","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/S0749-0712(21)00337-1","article-title":"The wrist in rheumatoid arthritis","volume":"12","author":"Shapiro","year":"1996","journal-title":"Hand Clin"},{"issue":"1","key":"10.1016\/j.hcl.2024.07.006_bib7","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.hcl.2010.09.004","article-title":"Current concepts and treatment for the rheumatoid wrist","volume":"27","author":"Rizzo","year":"2011","journal-title":"Hand Clin"},{"issue":"2","key":"10.1016\/j.hcl.2024.07.006_bib8","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.jht.2013.12.002","article-title":"Update on the surgical treatment for rheumatoid arthritis of the wrist and hand","volume":"27","author":"Chim","year":"2014","journal-title":"J\u00a0Hand Ther"},{"key":"10.1016\/j.hcl.2024.07.006_bib9","series-title":"Rheumatoid arthritis in adults: management","year":"2018"},{"key":"10.1016\/j.hcl.2024.07.006_bib10","series-title":"Adalimumab, etanercept, infliximab and abatacept for treating moderate rheumatoid arthritis after conventional DMARDs have failed","year":"2021"},{"issue":"2","key":"10.1016\/j.hcl.2024.07.006_bib11","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1007\/s11552-014-9708-9","article-title":"Rheumatoid hand surgery: is there a decline? a 22-year population-based study","volume":"10","author":"Gogna","year":"2015","journal-title":"Hand"},{"issue":"12","key":"10.1016\/j.hcl.2024.07.006_bib12","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1093\/rheumatology\/32.12.1089","article-title":"Synovectomy of the hand","volume":"32","author":"Wynn Parry","year":"1993","journal-title":"Br J Rheumatol"},{"issue":"6","key":"10.1016\/j.hcl.2024.07.006_bib13","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/j.bjps.2011.11.050","article-title":"Change in operative workload for rheumatoid disease of the hand: 1,109 procedures over 13 years","volume":"65","author":"Dafydd","year":"2012","journal-title":"J\u00a0Plast Reconstr Aesthetic Surg"},{"key":"10.1016\/j.hcl.2024.07.006_bib14","doi-asserted-by":"crossref","first-page":"100","DOI":"10.2174\/1874312901105010100","article-title":"The normal synovium","volume":"5","author":"Smith","year":"2011","journal-title":"Open Rheumatol J"},{"issue":"6","key":"10.1016\/j.hcl.2024.07.006_bib15","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/s41584-020-0413-5","article-title":"Restoring synovial homeostasis in rheumatoid arthritis by targeting fibroblast-like synoviocytes","volume":"16","author":"Nygaard","year":"2020","journal-title":"Nat Rev Rheumatol"},{"issue":"7987","key":"10.1016\/j.hcl.2024.07.006_bib16","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1038\/s41586-023-06708-y","article-title":"Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes","volume":"623","author":"Zhang","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.hcl.2024.07.006_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fimmu.2022.905356","article-title":"Synovial macrophages: past life, current situation, and application in inflammatory arthritis","volume":"13","author":"Bai","year":"2022","journal-title":"Front Immunol"},{"key":"10.1016\/j.hcl.2024.07.006_bib18","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1111\/j.1600-065X.2008.00648.x","article-title":"The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis","volume":"223","author":"Noss","year":"2008","journal-title":"Immunol Rev"},{"issue":"2","key":"10.1016\/j.hcl.2024.07.006_bib19","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1038\/ncprheum0047","article-title":"Mechanisms of disease: the molecular and cellular basis of joint destruction in rheumatoid arthritis","volume":"1","author":"M\u00fcller-Ladner","year":"2005","journal-title":"Nat Clin Pract Rheumatol"},{"issue":"4","key":"10.1016\/j.hcl.2024.07.006_bib20","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1136\/ard.47.4.348","article-title":"Synovial lining cell hyperplasia in rheumatoid arthritis: dogma and fact","volume":"47","author":"Henderson","year":"1988","journal-title":"Ann Rheum Dis"},{"issue":"8","key":"10.1016\/j.hcl.2024.07.006_bib21","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1002\/1529-0131(200108)44:8<1754::AID-ART310>3.0.CO;2-8","article-title":"Production of cytokines, vascular endothelial growth factor, matrix metalloproteinases, and tissue inhibitor of metalloproteinases 1 by tenosynovium demonstrates its potential for tendon destruction in rheumatoid arthritis","volume":"44","author":"Jain","year":"2001","journal-title":"Arthritis Rheum"},{"issue":"6","key":"10.1016\/j.hcl.2024.07.006_bib22","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1053\/jhsu.2002.36516","article-title":"The role of matrix metalloproteinases in rheumatoid tendon disease","volume":"27","author":"Jain","year":"2002","journal-title":"J\u00a0Hand Surg Am"},{"issue":"1","key":"10.1016\/j.hcl.2024.07.006_bib23","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.jhsa.2007.09.002","article-title":"Synovial hypoxia as a cause of tendon rupture in rheumatoid arthritis","volume":"33","author":"Sivakumar","year":"2008","journal-title":"J\u00a0Hand Surg Am"},{"issue":"3","key":"10.1016\/j.hcl.2024.07.006_bib24","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.hcl.2011.06.001","article-title":"Arthroscopic synovectomy of the wrist","volume":"27","author":"Adolfsson","year":"2011","journal-title":"Hand Clin"},{"issue":"2","key":"10.1016\/j.hcl.2024.07.006_bib25","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1002\/jor.21233","article-title":"Surgical synovectomy decreases density of sensory nerve fibers in synovial tissue of non-inflamed controls and rheumatoid arthritis patients","volume":"29","author":"Ossyssek","year":"2011","journal-title":"J\u00a0Orthop Res"},{"issue":"3","key":"10.1016\/j.hcl.2024.07.006_bib26","first-page":"261","article-title":"Long-term results of synovectomy of the finger joints in rheumatoid arthritis","volume":"8","author":"Ryu","year":"1998","journal-title":"Japanese J Rheumatol."},{"issue":"6","key":"10.1016\/j.hcl.2024.07.006_bib27","doi-asserted-by":"crossref","first-page":"598","DOI":"10.3109\/s10165-011-0447-2","article-title":"Short-term outcome of finger joint synovectomy in rheumatoid arthritis","volume":"21","author":"Nakagawa","year":"2011","journal-title":"Mod Rheumatol"},{"issue":"2","key":"10.1016\/j.hcl.2024.07.006_bib28","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/0749-8063(90)90015-6","article-title":"Arthroscopic \u201c-ectomy\u201d surgery of the wrist","volume":"6","author":"Roth","year":"1990","journal-title":"Arthroscopy"},{"issue":"7","key":"10.1016\/j.hcl.2024.07.006_bib29","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1007\/s11999-010-1744-3","article-title":"Rheumatoid synovectomy: Does the surgical approach matter?","volume":"469","author":"Chalmers","year":"2011","journal-title":"Clin Orthop Relat Res"},{"issue":"4","key":"10.1016\/j.hcl.2024.07.006_bib30","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.hcl.2017.07.005","article-title":"Arthroscopic Synovectomy of Wrist in Rheumatoid Arthritis","volume":"33","author":"Shim","year":"2017","journal-title":"Hand Clin"},{"issue":"2","key":"10.1016\/j.hcl.2024.07.006_bib31","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1097\/RHU.0000000000001807","article-title":"Arthroscopic Synovectomy of the Wrist in Patients with Rheumatoid Arthritis: A Systematic Review of the Current Literature","volume":"28","author":"D\u2019Ailly","year":"2022","journal-title":"J\u00a0Clin Rheumatol"},{"issue":"1","key":"10.1016\/j.hcl.2024.07.006_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13063-023-07129-y","article-title":"Arthroscopic synovectomy versus intra-articular injection of corticosteroids for the management of refractory psoriatic or rheumatoid arthritis of the wrist: study protocol for a randomized controlled trial (ARCTIC trial)","volume":"24","author":"d\u2019Ailly","year":"2023","journal-title":"Trials"},{"issue":"7","key":"10.1016\/j.hcl.2024.07.006_bib33","doi-asserted-by":"crossref","first-page":"e1155","DOI":"10.1016\/j.eats.2023.03.004","article-title":"Arthroscopic complete synovectomy of the proximal interphalangeal joint of the finger","volume":"12","author":"Lam","year":"2023","journal-title":"Arthrosc Tech"},{"issue":"03","key":"10.1016\/j.hcl.2024.07.006_bib34","first-page":"186","article-title":"Wrist arthroscopy in juvenile idiopathic arthritis: a review of current literature and future implications","volume":"07","author":"Vermaak","year":"2018","journal-title":"J\u00a0Wrist Surg"},{"issue":"6","key":"10.1016\/j.hcl.2024.07.006_bib35","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1007\/s00264-011-1428-y","article-title":"Wrist arthroscopy in children and adolescents: a single surgeon experience of thirty-four cases","volume":"36","author":"Farr","year":"2012","journal-title":"Int Orthop"},{"issue":"03","key":"10.1016\/j.hcl.2024.07.006_bib36","first-page":"239","article-title":"Arthroscopic capsular shrinkage is safe and effective in the treatment of midcarpal instability in a pediatric population: a single-center experience of 51 cases","volume":"12","author":"Wharton","year":"2023","journal-title":"J\u00a0Wrist Surg"},{"issue":"05","key":"10.1016\/j.hcl.2024.07.006_bib37","first-page":"376","article-title":"Role of wrist arthroscopy in juvenile inflammatory arthritis","volume":"11","author":"Ishwar","year":"2022","journal-title":"J\u00a0Wrist Surg"},{"issue":"3","key":"10.1016\/j.hcl.2024.07.006_bib38","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.jbspin.2018.11.007","article-title":"The Tuck sign-proliferative extensor tenosynovitis of the wrist","volume":"86","author":"Achilleos","year":"2019","journal-title":"Jt Bone Spine"},{"issue":"3","key":"10.1016\/j.hcl.2024.07.006_bib39","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1302\/0301-620X.30B3.528","article-title":"Rupture of extensor tendons by attrition at the inferior radio-ulnar joint; report of two cases","volume":"30B","author":"Vaughan-Jackson","year":"1948","journal-title":"J\u00a0Bone Joint Surg Br"},{"issue":"3","key":"10.1016\/j.hcl.2024.07.006_bib40","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.otsr.2018.08.020","article-title":"Combined synovectomy and extensor carpi radialis longus transfer to realign and stabilise the rheumatoid wrist","volume":"105","author":"Berhouet","year":"2019","journal-title":"Orthop Traumatol Surg Res"},{"issue":"5","key":"10.1016\/j.hcl.2024.07.006_bib41","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1302\/0301-620X.78B5.0780783","article-title":"Wrist arthrodesis in rheumatoid arthritis. A new technique using internal fixation","volume":"78","author":"Pech","year":"1996","journal-title":"J\u00a0Bone Joint Surg Br."},{"issue":"2","key":"10.1016\/j.hcl.2024.07.006_bib42","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0749-0712(21)01082-9","article-title":"Distal ulna resection, extensor carpi ulnaris tenodesis, and dorsal synovectomy for the rheumatoid wrist","volume":"7","author":"Melone","year":"1991","journal-title":"Hand Clin"},{"issue":"4","key":"10.1016\/j.hcl.2024.07.006_bib43","first-page":"497","article-title":"Flexor synovectomy as an adjunct to carpal tunnel release in primary carpal tunnel syndrome: a meta-analysis","volume":"26","author":"Chiang","year":"2021","journal-title":"J\u00a0hand Surg Asian-Pacific"},{"issue":"2","key":"10.1016\/j.hcl.2024.07.006_bib44","doi-asserted-by":"crossref","first-page":"221","DOI":"10.2106\/00004623-200202000-00009","article-title":"The role of flexor tenosynovectomy in the operative treatment of carpal tunnel syndrome","volume":"84","author":"Shum","year":"2002","journal-title":"J\u00a0Bone Joint Surg Am"},{"issue":"7","key":"10.1016\/j.hcl.2024.07.006_bib45","doi-asserted-by":"crossref","first-page":"2020","DOI":"10.1097\/01.PRS.0000122216.24878.1F","article-title":"A\u00a0comparison of flexor tenosynovectomy, open carpal tunnel release, and open carpal tunnel release with flexor tenosynovectomy in the treatment of carpal tunnel syndrome","volume":"113","author":"Ketchum","year":"2004","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.hcl.2024.07.006_bib46","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1051\/sicotj\/2017009","article-title":"Can flexor tenosynovectomy and microsurgical epineurectomy improve clinical outcomes following open carpal tunnel release?","volume":"3","author":"Duman","year":"2017","journal-title":"Sicot-J."},{"issue":"1","key":"10.1016\/j.hcl.2024.07.006_bib47","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1177\/1558944719840735","article-title":"Flexor tenosynovectomy for recurrent carpal tunnel syndrome: a retrospective case series of 108 hands","volume":"16","author":"Kluemper","year":"2021","journal-title":"Hand"},{"key":"10.1016\/j.hcl.2024.07.006_bib48","first-page":"431","article-title":"Recurrent and persistent carpal tunnel syndrome: \u201cTriple-therapy approach.\u201d","volume":"22","author":"Spielman","year":"2020","journal-title":"J\u00a0Orthop"}],"container-title":["Hand Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749071224000568?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749071224000568?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T11:17:10Z","timestamp":1756466230000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0749071224000568"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["S0749071224000568"],"URL":"https:\/\/doi.org\/10.1016\/j.hcl.2024.07.006","relation":{},"ISSN":["0749-0712"],"issn-type":[{"value":"0749-0712","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of Synovectomy in Rheumatoid Hand and Wrist","name":"articletitle","label":"Article Title"},{"value":"Hand Clinics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hcl.2024.07.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}