{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T07:58:28Z","timestamp":1769068708150,"version":"3.49.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jhltonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Heart and Lung Transplantation"],"published-print":{"date-parts":[[2009,10]]},"DOI":"10.1016\/j.healun.2009.05.024","type":"journal-article","created":{"date-parts":[[2009,9,25]],"date-time":"2009-09-25T12:43:37Z","timestamp":1253882617000},"page":"1075-1080","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Transfer of Cholesterol and Other Lipids From a Lipid Nanoemulsion to High-density Lipoprotein in Heart Transplant Patients"],"prefix":"10.1016","volume":"28","author":[{"given":"Camila G\u00f3es","family":"Puk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edimar Alcides","family":"Bocchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Cristina","family":"Lo Prete","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia Moreira Ayub","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noedir Ant\u00f4nio Groppo","family":"Stolf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raul Cavalcante","family":"Maranh\u00e3o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.healun.2009.05.024_bib1","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1097\/00007890-199802270-00015","article-title":"Cardiac allograft rejection late after transplantation is a risk factor for graft coronary artery disease","volume":"65","author":"Brunner-La Rocca","year":"1998","journal-title":"Transplantation"},{"key":"10.1016\/j.healun.2009.05.024_bib2","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1093\/oxfordjournals.eurheartj.a015296","article-title":"Graft vascular disease after heart transplantation","volume":"18","author":"Schmid","year":"1997","journal-title":"Eur Heart J"},{"key":"10.1016\/j.healun.2009.05.024_bib3","first-page":"319","article-title":"Cardiac allograft vasculopathy: a review","volume":"48","author":"Ramzy","year":"2005","journal-title":"Can J Surg"},{"key":"10.1016\/j.healun.2009.05.024_bib4","first-page":"454","article-title":"Dyslipoproteinemias after heart and heart\u2013lung transplantation: potential relation to accelerated graft arteriosclerosis","volume":"8","author":"Bilodeau","year":"1989","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2009.05.024_bib5","first-page":"572","article-title":"Lipid disorder and transplant coronary artery disease in long-term survivors of heart transplantation","volume":"15","author":"Park","year":"1996","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2009.05.024_bib6","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1161\/01.ATV.20.3.728","article-title":"Hypercholesterolemia increases coronary endothelial dysfunction, lipid content, and accelerated atherosclerosis after heart transplantation","volume":"20","author":"Perrault","year":"2000","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.healun.2009.05.024_bib7","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1097\/00007890-200204270-00012","article-title":"Risk factors for the development and progression of dyslipidemia after heart transplantation","volume":"73","author":"Akhlaghi","year":"2002","journal-title":"Transplantation"},{"key":"10.1016\/j.healun.2009.05.024_bib8","first-page":"263","article-title":"Lipid profile changes during the late follow-up after heart transplantation","volume":"66","author":"Bellotti","year":"1996","journal-title":"Arq Bras Cardiol"},{"key":"10.1016\/j.healun.2009.05.024_bib9","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1097\/01.TP.0000137788.15004.7F","article-title":"Plasma kinetics of a cholesterol-rich microemulsion in patients submitted to heart transplantation","volume":"78","author":"Puk","year":"2004","journal-title":"Transplantation"},{"key":"10.1016\/j.healun.2009.05.024_bib10","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1097\/00007890-200002270-00012","article-title":"Chylomicron metabolism in patients submitted to cardiac transplantation","volume":"69","author":"Vinagre","year":"2000","journal-title":"Transplantation"},{"key":"10.1016\/j.healun.2009.05.024_bib11","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1097\/01.tp.0000197556.83675.a6","article-title":"Elevated HDL cholesterol is functionally ineffective in cardiac transplant recipients: evidence for impaired reverse cholesterol transport","volume":"81","author":"Sviridov","year":"2006","journal-title":"Transplantation"},{"key":"10.1016\/j.healun.2009.05.024_bib12","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1016\/0002-9149(88)90272-X","article-title":"Frequency of hypercholesterolemia after cardiac transplantation","volume":"62","author":"Stamler","year":"1988","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.healun.2009.05.024_bib13","doi-asserted-by":"crossref","first-page":"2877","DOI":"10.1016\/j.transproceed.2005.05.010","article-title":"High prevalence of small dense LDL as an underestimated component of heart transplantation-induced dyslipidemia: potential role in graft coronary vasculopathy?","volume":"37","author":"Badiou","year":"2005","journal-title":"Transplant Proc"},{"issue":"suppl","key":"10.1016\/j.healun.2009.05.024_bib14","doi-asserted-by":"crossref","first-page":"12E","DOI":"10.1016\/S0002-9149(02)03383-0","article-title":"High-density lipoprotein subpopulations in pathologic conditions","volume":"91","author":"Asztalos","year":"2003","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.healun.2009.05.024_bib15","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1021\/cr020466v","article-title":"HDL: the metabolism, function, and therapeutic importance","volume":"104","author":"Wang","year":"2004","journal-title":"Chem Rev"},{"key":"10.1016\/j.healun.2009.05.024_bib16","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/S0022-2275(20)38087-1","article-title":"Human apolipoprotein A-I and A-II metabolism","volume":"23","author":"Schaefer","year":"1982","journal-title":"J Lipid Res"},{"key":"10.1016\/j.healun.2009.05.024_bib17","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1161\/01.ATV.21.1.13","article-title":"High density lipoproteins and arteriosclerosis: role of cholesterol efflux and reverse cholesterol transport","volume":"21","author":"von Eckardstein","year":"2001","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.healun.2009.05.024_bib18","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1161\/01.RES.0000170946.56981.5c","article-title":"New insights into the regulation of HDL metabolism and reverse cholesterol transport","volume":"96","author":"Lewis","year":"2005","journal-title":"Circ Res"},{"key":"10.1016\/j.healun.2009.05.024_bib19","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1172\/JCI28632","article-title":"Putting cholesterol in its place: apo E and reverse cholesterol transport","volume":"116","author":"Mahley","year":"2006","journal-title":"J Clin Invest"},{"issue":"suppl","key":"10.1016\/j.healun.2009.05.024_bib20","doi-asserted-by":"crossref","first-page":"C7","DOI":"10.1016\/j.jacc.2005.09.068","article-title":"Pathogenesis of atherosclerosis","volume":"47","author":"Falk","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.healun.2009.05.024_bib21","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0021-9150(01)00677-3","article-title":"Dynamics of reverse cholesterol transport; protection against atherosclerosis","volume":"161","author":"Sviridov","year":"2002","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.healun.2009.05.024_bib22","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0002-9149(90)90517-5","article-title":"Lipoprotein and hepatic lipase activity and high-density lipoprotein subclasses after cardiac transplantation","volume":"66","author":"Superko","year":"1990","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.healun.2009.05.024_bib23","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/clinchem\/18.6.499","article-title":"Estimation of the concentration of the low density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge","volume":"18","author":"Friedewald","year":"1972","journal-title":"Clin Chem"},{"key":"10.1016\/j.healun.2009.05.024_bib24","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0021-9150(91)90215-O","article-title":"Serum paraoxonase activity in familial hypercholesterolaemia and insulin-dependent diabetes mellitus","volume":"86","author":"Mackness","year":"1991","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.healun.2009.05.024_bib25","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1373\/clinchem.2004.032383","article-title":"Rapid, simple laser-light scattering method for HDL particle size in whole plasma","volume":"50","author":"Lima","year":"2004","journal-title":"Clin Chem"},{"key":"10.1016\/j.healun.2009.05.024_bib26","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1007\/BF02535988","article-title":"Metabolic behavior in rats of a nonprotein microemulsion resembling low-density lipoprotein","volume":"28","author":"Maranh\u00e3o","year":"1993","journal-title":"Lipids"},{"key":"10.1016\/j.healun.2009.05.024_bib27","series-title":"Guidance for Industry","year":"2001"},{"key":"10.1016\/j.healun.2009.05.024_bib28","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.atherosclerosis.2004.10.008","article-title":"Lipid transfer proteins (LTP) and atherosclerosis","volume":"178","author":"Stein","year":"2005","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.healun.2009.05.024_bib29","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1161\/01.CIR.0000079163.97653.CD","article-title":"Cell-associated and extracellular phospholipid transfer protein in human coronary atherosclerosis","volume":"108","author":"O'Brien","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.healun.2009.05.024_bib30","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1097\/01.hco.0000231405.76930.a0","article-title":"Determinants of plasma HDL concentrations and reverse cholesterol","volume":"21","author":"Lewis","year":"2006","journal-title":"Curr Opin Cardiol"},{"key":"10.1016\/j.healun.2009.05.024_bib31","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.ijgo.2008.10.001","article-title":"HDL concentration, lipid transfer to HDL, and HDL size in normolipidemic nonobese menopausal women","volume":"104","author":"Giribela","year":"2009","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1016\/j.healun.2009.05.024_bib32","unstructured":"Rocha MP, Maranh\u00e3o RC, Seydell TM, et al. Metabolism of triglyceride-rich lipoproteins and transfer of lipids to high-density lipoprotein in young obese and normal weight patients with polycystic ovary syndrome. Fertil Steril (in press)."},{"key":"10.1016\/j.healun.2009.05.024_bib33","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1194\/jlr.M200331-JLR200","article-title":"Plasma kinetics of a cholesterol-rich emulsion in subjects with or without coronary artery disease","volume":"44","author":"Santos","year":"2003","journal-title":"J Lipid Res"},{"key":"10.1016\/j.healun.2009.05.024_bib34","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1007\/s11745-007-3041-9","article-title":"Deposition of free cholesterol in the blood vessels of patients with coronary artery disease: a possible novel mechanism for atherogenesis","volume":"42","author":"Couto","year":"2007","journal-title":"Lipids"},{"key":"10.1016\/j.healun.2009.05.024_bib35","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S1567-5688(08)70087-4","article-title":"Capacity of the high density lipoprotein to receive lipids in age groups: a study using an artificial nanoemulsion","volume":"9","author":"Azevedo","year":"2008","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.healun.2009.05.024_bib36","doi-asserted-by":"crossref","first-page":"207","DOI":"10.5551\/jat.9.207","article-title":"Effect of HMG-CoA redutase inhibitor on plasma cholesteryl ester transfer protein activity in primary hypercholesterolemia: comparison among CETP\/TaqIB genotype subgroups","volume":"9","author":"Kotake","year":"2002","journal-title":"J Atheroscler Thromb"},{"key":"10.1016\/j.healun.2009.05.024_bib37","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1016\/j.healun.2004.05.023","volume":"24","author":"White","year":"2005","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2009.05.024_bib38","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.bcp.2004.08.027","article-title":"Modulation of paraoxonase (pon1) activity","volume":"69","author":"Costa","year":"2005","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.healun.2009.05.024_bib39","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1161\/01.ATV.0000256728.60226.77","article-title":"The failure of Torcetrapib: was it the molecule or the mechanism?","volume":"27","author":"Tall","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"}],"container-title":["The Journal of Heart and Lung Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053249809003672?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053249809003672?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T08:19:29Z","timestamp":1760948369000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1053249809003672"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10]]},"references-count":39,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2009,10]]}},"alternative-id":["S1053249809003672"],"URL":"https:\/\/doi.org\/10.1016\/j.healun.2009.05.024","relation":{},"ISSN":["1053-2498"],"issn-type":[{"value":"1053-2498","type":"print"}],"subject":[],"published":{"date-parts":[[2009,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transfer of Cholesterol and Other Lipids From a Lipid Nanoemulsion to High-density Lipoprotein in Heart Transplant Patients","name":"articletitle","label":"Article Title"},{"value":"The Journal of Heart and Lung Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.healun.2009.05.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}