{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T21:54:22Z","timestamp":1761947662950,"version":"build-2065373602"},"reference-count":22,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jhltonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Heart and Lung Transplantation"],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1016\/j.healun.2010.06.015","type":"journal-article","created":{"date-parts":[[2010,9,21]],"date-time":"2010-09-21T04:44:21Z","timestamp":1285044261000},"page":"1286-1292","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Cardiomyocyte survivin protein expression is associated with cell size and DNA content in the failing human heart and is reversibly regulated after ventricular unloading"],"prefix":"10.1016","volume":"29","author":[{"given":"Jeremias","family":"Wohlschlaeger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birgit","family":"Meier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus J\u00fcrgen","family":"Schmitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Takeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuakira","family":"Takeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Vahlhaus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bodo","family":"Levkau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f6rg","family":"Stypmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christof","family":"Schmid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kurt","family":"Werner Schmid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideo Andreas","family":"Baba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.healun.2010.06.015_bib1","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.cardiores.2004.02.013","article-title":"Myocyte hypertrophy and apoptosis: a balancing act","volume":"63","author":"van Empel","year":"2004","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.healun.2010.06.015_bib2","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1253\/circj.66.225","article-title":"Proliferative signaling and disease progression in heart failure","volume":"66","author":"Katz","year":"2002","journal-title":"Circ J"},{"key":"10.1016\/j.healun.2010.06.015_bib3","first-page":"45","article-title":"Reversal of myocyte hypertrophy by ventricular unloading: cardiac improvement without adrenergic receptor up-regulation and relocalization","volume":"8","author":"Schnee","year":"2006","journal-title":"MedGenMed"},{"key":"10.1016\/j.healun.2010.06.015_bib4","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.healun.2010.01.007","article-title":"Cardiac fibrosis and cellular hypertrophy decrease the degree of reverse remodeling and improvement in cardiac function during left ventricular assist","volume":"29","author":"Saito","year":"2010","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2010.06.015_bib5","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1016\/j.healun.2003.09.005","article-title":"Effect of left ventricular assist device combination therapy on myocardial blood flow in patients with end-stage dilated cardiomyopathy","volume":"23","author":"Tansley","year":"2004","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2010.06.015_bib6","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1161\/CIRCULATIONAHA.108.808071","article-title":"Hemodynamic support by left ventricular assist devices reduces cardiomyocyte DNA content in the failing human heart","volume":"121","author":"Wohlschlaeger","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.healun.2010.06.015_bib7","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1006\/jmcc.1998.0808","article-title":"Expressions and activities of cell cycle regulatory molecules during the transition from myocyte hyperplasia to hypertrophy","volume":"30","author":"Poolman","year":"1998","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.healun.2010.06.015_bib8","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S0008-6363(02)00510-2","article-title":"Involvement of cyclin D activity in left ventricle hypertrophy in vivo and in vitro","volume":"56","author":"Busk","year":"2002","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.healun.2010.06.015_bib9","doi-asserted-by":"crossref","first-page":"4543","DOI":"10.1093\/emboj\/19.17.4543","article-title":"The Drosophila cyclin D-Cdk4 complex promotes cellular growth","volume":"19","author":"Datar","year":"2000","journal-title":"EMBO J"},{"key":"10.1016\/j.healun.2010.06.015_bib10","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1038\/nm0897-917","article-title":"A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma","volume":"3","author":"Ambrosini","year":"1997","journal-title":"Nat Med"},{"key":"10.1016\/j.healun.2010.06.015_bib11","doi-asserted-by":"crossref","DOI":"10.1038\/nrm2257","article-title":"Chromosomal passengers: conducting cell division","volume":"8","author":"Ruchaud","year":"2007","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.healun.2010.06.015_bib12","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0074-7696(05)47002-3","article-title":"Survivin: a protein with dual roles in mitosis and apoptosis","volume":"247","author":"Wheatley","year":"2005","journal-title":"Int Rev Cytol"},{"key":"10.1016\/j.healun.2010.06.015_bib13","doi-asserted-by":"crossref","first-page":"3225","DOI":"10.1038\/sj.onc.1203665","article-title":"Survivin initiates cell cycle entry by the competitive interaction with Cdk4\/p16(INK4a) and Cdk2\/cyclin E complex activation","volume":"19","author":"Suzuki","year":"2000","journal-title":"Oncogene"},{"key":"10.1016\/j.healun.2010.06.015_bib14","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1136\/jcp.2004.018986","article-title":"Surviving acute myocardial infarction: survivin expression in viable cardiomyocytes after infarction","volume":"57","author":"Santini","year":"2004","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.healun.2010.06.015_bib15","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1161\/CIRCULATIONAHA.107.734160","article-title":"Survivin determines cardiac function by controlling total cardiomyocyte number","volume":"117","author":"Levkau","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.healun.2010.06.015_bib16","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/S1053-2498(00)00074-7","article-title":"Reversal of metallothionein expression is different throughout the human myocardium after prolonged left-ventricular mechanical support","volume":"19","author":"Baba","year":"2000","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2010.06.015_bib17","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1161\/01.CIR.98.7.656","article-title":"Regression of cellular hypertrophy after left ventricular assist device support","volume":"98","author":"Zafeiridis","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.healun.2010.06.015_bib18","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1111\/j.1365-2184.2008.00549.x","article-title":"Phosphorylation of pRb by cyclin D kinase is necessary for development of cardiac hypertrophy","volume":"41","author":"Hinrichsen","year":"2008","journal-title":"Cell Prolif"},{"key":"10.1016\/j.healun.2010.06.015_bib19","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.healun.2009.09.017","article-title":"Reversible regulation of the retinoblastoma protein\/E2F-1 pathway during \u201creverse cardiac remodelling\u201d after ventricular unloading","volume":"29","author":"Wohlschlaeger","year":"2010","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2010.06.015_bib20","first-page":"115","article-title":"Polyploidization of heart muscle nuclei as a prerequisite for heart growth and numerical hyperplasia in heart hypertrophy","volume":"12","author":"Sandritter","year":"1976","journal-title":"Recent Adv Stud Cardiac Struct Metab"},{"key":"10.1016\/j.healun.2010.06.015_bib21","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1038\/202100a0","article-title":"Deoxyribonucleic acid content (Feulgen photometry) and dry weight (interference microscopy) of normal and hypertrophic heart muscle fibers","volume":"202","author":"Sandritter","year":"1964","journal-title":"Nature"},{"key":"10.1016\/j.healun.2010.06.015_bib22","article-title":"Downregulation of survivin and aurora a by histone deacetylase and RAS inhibitors: A new drug combination for cancer therapy","author":"Biran","year":"2010","journal-title":"Int J Cancer"}],"container-title":["The Journal of Heart and Lung Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053249810004407?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053249810004407?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T08:21:53Z","timestamp":1760948513000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1053249810004407"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":22,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["S1053249810004407"],"URL":"https:\/\/doi.org\/10.1016\/j.healun.2010.06.015","relation":{},"ISSN":["1053-2498"],"issn-type":[{"type":"print","value":"1053-2498"}],"subject":[],"published":{"date-parts":[[2010,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cardiomyocyte survivin protein expression is associated with cell size and DNA content in the failing human heart and is reversibly regulated after ventricular unloading","name":"articletitle","label":"Article Title"},{"value":"The Journal of Heart and Lung Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.healun.2010.06.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}