{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T07:52:27Z","timestamp":1793433147843,"version":"4.5.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jhltonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Heart and Lung Transplantation"],"published-print":{"date-parts":[[2011,7]]},"DOI":"10.1016\/j.healun.2011.03.007","type":"journal-article","created":{"date-parts":[[2011,4,25]],"date-time":"2011-04-25T06:11:50Z","timestamp":1303711910000},"page":"819-826","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Reduction of cold ischemia\u2013reperfusion injury by graft-expressing clusterin in heart transplantation"],"prefix":"10.1016","volume":"30","author":[{"given":"Shuyuan","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiunong","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhishui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin E.","family":"Gleave","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher Y.C.","family":"Nguan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caigan","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.healun.2011.03.007_bib1","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1093\/ndt\/gfl042","article-title":"Major effects of delayed graft function and cold ischaemia time on renal allograft survival","volume":"21","author":"Quiroga","year":"2006","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.healun.2011.03.007_bib2","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1111\/j.1432-2277.2010.01126.x","article-title":"Cold ischemia contributes to the development of chronic rejection and mitochondrial injury after cardiac transplantation","volume":"23","author":"Schneeberger","year":"2010","journal-title":"Transpl Int"},{"key":"10.1016\/j.healun.2011.03.007_bib3","doi-asserted-by":"crossref","first-page":"II-223","DOI":"10.1161\/01.CIR.92.9.223","article-title":"Discriminating between preservation and reperfusion injury in human cardiac allografts using heart weight and left ventricular mass","volume":"92","author":"Slater","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.healun.2011.03.007_bib4","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1097\/00007890-199710270-00003","article-title":"Cold ischemic injury accelerates the progression to chronic rejection in a rat cardiac allograft model","volume":"64","author":"Knight","year":"1997","journal-title":"Transplantation"},{"key":"10.1016\/j.healun.2011.03.007_bib5","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1016\/j.healun.2004.06.007","article-title":"Prolonged cold ischemia in rat cardiac allografts promotes ischemia\u2013reperfusion injury and the development of graft coronary artery disease in a linear fashion","volume":"24","author":"Tanaka","year":"2005","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2011.03.007_bib6","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S1357-2725(01)00155-8","article-title":"Clusterin","volume":"34","author":"Jones","year":"2002","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.healun.2011.03.007_bib7","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1073\/pnas.90.2.725","article-title":"Apolipoprotein J expression at fluid\u2013tissue interfaces: potential role in barrier cytoprotection","volume":"90","author":"Aronow","year":"1993","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.healun.2011.03.007_bib8","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1161\/01.ATV.18.4.665","article-title":"Distribution and synthesis of apolipoprotein J in the atherosclerotic aorta","volume":"18","author":"Ishikawa","year":"1998","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.healun.2011.03.007_bib9","first-page":"1971","article-title":"Apolipoprotein J\/clusterin induction in myocarditis: a localized response gene to myocardial injury","volume":"148","author":"Swertfeger","year":"1996","journal-title":"Am J Pathol"},{"key":"10.1016\/j.healun.2011.03.007_bib10","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1172\/JCI9037","article-title":"Apolipoprotein J\/clusterin limits the severity of murine autoimmune myocarditis","volume":"106","author":"McLaughlin","year":"2000","journal-title":"J Clin Invest"},{"key":"10.1016\/j.healun.2011.03.007_bib11","doi-asserted-by":"crossref","first-page":"F568","DOI":"10.1152\/ajprenal.00399.2009","article-title":"Loss of clusterin expression worsens renal ischemia-reperfusion injury","volume":"298","author":"Zhou","year":"2010","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.healun.2011.03.007_bib12","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1038\/nm0901-977","article-title":"Inhibition of post-ischemic brain injury by clusterin overexpression","volume":"7","author":"Wehrli","year":"2001","journal-title":"Nat Med"},{"key":"10.1016\/j.healun.2011.03.007_bib13","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1161\/01.CIR.85.5.1835","article-title":"Gene expression and atrial natriuretic factor processing and secretion in cultured AT-1 cardiac myocytes","volume":"85","author":"Lanson","year":"1992","journal-title":"Circulation"},{"key":"10.1016\/j.healun.2011.03.007_bib14","doi-asserted-by":"crossref","first-page":"F1044","DOI":"10.1152\/ajprenal.00341.2005","article-title":"Nitric oxide induces apoptosis in renal tubular epithelial cells through activation of caspase-8","volume":"290","author":"Du","year":"2006","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.healun.2011.03.007_bib15","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1097\/01.tp.0000251374.49225.19","article-title":"Prolongation of cardiac allograft survival by inhibition of ERK1\/2 signaling in a mouse model","volume":"83","author":"Wang","year":"2007","journal-title":"Transplantation"},{"key":"10.1016\/j.healun.2011.03.007_bib16","doi-asserted-by":"crossref","first-page":"H1633","DOI":"10.1152\/ajpheart.00701.2003","article-title":"Mitochondrial defects and heterogeneous cytochrome c release after cardiac cold ischemia and reperfusion","volume":"286","author":"Kuznetsov","year":"2004","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.healun.2011.03.007_bib17","first-page":"H1017","article-title":"Endotoxemia and neutrophil activation in vivo","volume":"254","author":"Grisham","year":"1988","journal-title":"Am J Physiol"},{"key":"10.1016\/j.healun.2011.03.007_bib18","series-title":"Physiology of cold sensitivity","author":"Denlinger","year":"1998"},{"key":"10.1016\/j.healun.2011.03.007_bib19","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1126\/science.223.4637.701","article-title":"Preservation of membranes in anhydrobiotic organisms: the role of trehalose","volume":"223","author":"Crowe","year":"1984","journal-title":"Science"},{"key":"10.1016\/j.healun.2011.03.007_bib20","first-page":"165","article-title":"Cell death: apoptosis versus necrosis","volume":"21","author":"Kanduc","year":"2002","journal-title":"Int J Oncol"},{"key":"10.1016\/j.healun.2011.03.007_bib21","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3727\/000000003783985160","article-title":"Induction of necrosis and DNA fragmentation during hypothermic preservation of hepatocytes in UW, HTK, and Celsior solutions","volume":"12","author":"Abrahamse","year":"2003","journal-title":"Cell Transplant"},{"key":"10.1016\/j.healun.2011.03.007_bib22","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1097\/00007890-200109150-00010","article-title":"Apoptosis versus necrosis during cold storage and rewarming of human renal proximal tubular cells","volume":"72","author":"Salahudeen","year":"2001","journal-title":"Transplantation"},{"key":"10.1016\/j.healun.2011.03.007_bib23","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1080\/15216540310001640498","article-title":"Small heat-shock proteins and clusterin: intra- and extracellular molecular chaperones with a common mechanism of action and function?","volume":"55","author":"Carver","year":"2003","journal-title":"IUBMB Life"},{"key":"10.1016\/j.healun.2011.03.007_bib24","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.1600-0676.1994.tb00007.x","article-title":"Preservation of human liver grafts in UW solution","volume":"14","author":"Carles","year":"1994","journal-title":"Liver"},{"key":"10.1016\/j.healun.2011.03.007_bib25","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1046\/j.1523-1755.2001.0600031173.x","article-title":"Prolonged cold preservation augments vascular injury independent of renal transplant immunogenicity and function","volume":"60","author":"Dragun","year":"2001","journal-title":"Kidney Int"},{"key":"10.1016\/j.healun.2011.03.007_bib26","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/S0022-5223(96)70104-6","article-title":"Cold ischemia-induced damage to vascular endothelium results in permeability alterations in transplanted lungs","volume":"112","author":"Hidalgo","year":"1996","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.healun.2011.03.007_bib27","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1177\/030006059502300307","article-title":"Pulmonary endothelial cell modifications after storage in solid-organ preservation solutions","volume":"23","author":"Carbognani","year":"1995","journal-title":"J Int Med Res"},{"key":"10.1016\/j.healun.2011.03.007_bib28","first-page":"685","article-title":"The pathology of rat lung isografts following 48 or 72-hour cold storage and subsequent reperfusion in vivo for up to 1 month","volume":"73","author":"Pickford","year":"1992","journal-title":"Int J Exp Pathol"},{"key":"10.1016\/j.healun.2011.03.007_bib29","first-page":"2789","article-title":"Protective effect of clusterin on oxidative stress-induced cell death of human corneal endothelial cells","volume":"15","author":"Shin","year":"2009","journal-title":"Mol Vis"},{"key":"10.1016\/j.healun.2011.03.007_bib30","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1080\/02713680701487871","article-title":"The role of clusterin in in vitro ischemia of human retinal endothelial cells","volume":"32","author":"Kim","year":"2007","journal-title":"Curr Eye Res"}],"container-title":["The Journal of Heart and Lung Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053249811008692?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053249811008692?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T08:23:17Z","timestamp":1760948597000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1053249811008692"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7]]},"references-count":30,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["S1053249811008692"],"URL":"https:\/\/doi.org\/10.1016\/j.healun.2011.03.007","relation":{},"ISSN":["1053-2498"],"issn-type":[{"value":"1053-2498","type":"print"}],"subject":[],"published":{"date-parts":[[2011,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Reduction of cold ischemia\u2013reperfusion injury by graft-expressing clusterin in heart transplantation","name":"articletitle","label":"Article Title"},{"value":"The Journal of Heart and Lung Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.healun.2011.03.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}