{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T19:34:51Z","timestamp":1781206491326,"version":"3.54.1"},"reference-count":24,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jhltonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Heart and Lung Transplantation"],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.1016\/j.healun.2014.02.016","type":"journal-article","created":{"date-parts":[[2014,2,21]],"date-time":"2014-02-21T19:45:37Z","timestamp":1393011937000},"page":"721-726","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"title":["Impact of insulin resistance on ventricular function in pulmonary arterial hypertension"],"prefix":"10.1016","volume":"33","author":[{"given":"Nathan W.","family":"Brunner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Skhiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Fortenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Hsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francois","family":"Haddad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nayer","family":"Khazeni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roham T.","family":"Zamanian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.healun.2014.02.016_bib1","doi-asserted-by":"crossref","first-page":"2250","DOI":"10.1161\/CIRCULATIONAHA.109.192230","volume":"119","author":"McLaughlin","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.healun.2014.02.016_bib2","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0140-6736(09)61794-3","article-title":"The metabolic syndrome","volume":"375","author":"Eckel","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.healun.2014.02.016_bib3","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/j.jacc.2010.05.034","article-title":"The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis","volume":"56","author":"Mottillo","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.healun.2014.02.016_bib4","doi-asserted-by":"crossref","first-page":"2362","DOI":"10.1056\/NEJMoa031049","article-title":"Obesity and the metabolic syndrome in children and adolescents","volume":"350","author":"Weiss","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.healun.2014.02.016_bib5","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1183\/09031936.00000508","article-title":"Insulin resistance in pulmonary arterial hypertension","volume":"33","author":"Zamanian","year":"2009","journal-title":"Eur Respir J"},{"key":"10.1016\/j.healun.2014.02.016_bib6","first-page":"904","article-title":"Unrecognized glucose intolerance is common in pulmonary arterial hypertension","volume":"30","author":"Pugh","year":"2011","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2014.02.016_bib7","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1164\/rccm.201001-0007OC","article-title":"Plasma levels of high-density lipoprotein cholesterol and outcomes in pulmonary arterial hypertension","volume":"182","author":"Heresi","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.healun.2014.02.016_bib8","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1136\/jech.2006.048173","article-title":"Association of metabolic syndrome and insulin resistance with congestive heart failure: findings from the third national health and nutrition examination survey","volume":"61","author":"Li","year":"2007","journal-title":"J Epidemiol Community Health"},{"key":"10.1016\/j.healun.2014.02.016_bib9","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1001\/jama.294.3.334","article-title":"Insulin resistance and risk of congestive heart failure","volume":"294","author":"Ingelsson","year":"2005","journal-title":"JAMA"},{"key":"10.1016\/j.healun.2014.02.016_bib10","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.jacc.2004.03.037","article-title":"Insulin resistance in idiopathic dilated cardiomyopathy: a possible etiologic link","volume":"44","author":"Witteles","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.healun.2014.02.016_bib11","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.2337\/dc09-9033","article-title":"International expert committee report on the role of the A1C assay in the diagnosis of diabetes","volume":"32","author":"International Expert Committee","year":"2009","journal-title":"Diabetes Care"},{"key":"10.1016\/j.healun.2014.02.016_bib12","doi-asserted-by":"crossref","first-page":"802","DOI":"10.7326\/0003-4819-139-10-200311180-00007","article-title":"Use of metabolic markers to identify overweight individuals who are insulin resistant","volume":"139","author":"McLaughlin","year":"2003","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.healun.2014.02.016_bib13","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1093\/cvr\/4.1.23","article-title":"The estimation of oxygen consumption","volume":"4","author":"LaFarge","year":"1970","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.healun.2014.02.016_bib14","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1164\/rccm.200910-1643OC","article-title":"Right ventricular oscillatory power is a constant fraction of total power irrespective of pulmonary artery pressure","volume":"182","author":"Saouti","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.healun.2014.02.016_bib15","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.echo.2010.05.010","volume":"23","author":"Rudski","year":"2010","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.healun.2014.02.016_bib16","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.echo.2008.11.023","article-title":"Recommendations for the evaluation of left ventricular diastolic function by echocardiography","volume":"22","author":"Nagueh","year":"2009","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.healun.2014.02.016_bib17","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/S0894-7317(96)90476-9","article-title":"Doppler echocardiographic index for assessment of global right ventricular function","volume":"9","author":"Tei","year":"1996","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.healun.2014.02.016_bib18","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1164\/ajrccm.166.1.at1102","article-title":"ATS statement: guidelines for the six-minute walk test","volume":"166","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"issue":"6 Suppl","key":"10.1016\/j.healun.2014.02.016_bib19","article-title":"The potential of biomarkers in pulmonary arterial hypertension","volume":"110","author":"Cracowski","year":"2012","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.healun.2014.02.016_bib20","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1159\/000338150","article-title":"Characterization of the role of nitric oxide and its clinical applications","volume":"122","author":"Levine","year":"2012","journal-title":"Cardiology"},{"key":"10.1016\/j.healun.2014.02.016_bib21","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1016\/j.echo.2005.05.002","article-title":"Plasma triglyceride level is an independent predictor of altered left ventricular relaxation","volume":"18","author":"de las Fuentes","year":"2005","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.healun.2014.02.016_bib22","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1093\/eurheartj\/ehl526","article-title":"Metabolic syndrome is associated with abnormal left ventricular diastolic function independent of left ventricular mass","volume":"28","author":"de las Fuentes","year":"2007","journal-title":"Eur Heart J"},{"key":"10.1016\/j.healun.2014.02.016_bib23","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1038\/nrcardio.2010.144","article-title":"Pulmonary hypertension with left-sided heart disease","volume":"7","author":"Guazzi","year":"2010","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.healun.2014.02.016_bib24","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1301\/nr.2003.dec.397-412","article-title":"Evaluation of insulin sensitivity in clinical practice and in research settings","volume":"61","author":"Monzillo","year":"2003","journal-title":"Nutr Rev"}],"container-title":["The Journal of Heart and Lung Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053249814009784?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053249814009784?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T08:27:34Z","timestamp":1760948854000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1053249814009784"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":24,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["S1053249814009784"],"URL":"https:\/\/doi.org\/10.1016\/j.healun.2014.02.016","relation":{},"ISSN":["1053-2498"],"issn-type":[{"value":"1053-2498","type":"print"}],"subject":[],"published":{"date-parts":[[2014,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of insulin resistance on ventricular function in pulmonary arterial hypertension","name":"articletitle","label":"Article Title"},{"value":"The Journal of Heart and Lung Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.healun.2014.02.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}