{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T17:19:44Z","timestamp":1792603184315,"version":"4.5.0"},"reference-count":45,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jhltonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Heart and Lung Transplantation"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1016\/j.healun.2016.01.1225","type":"journal-article","created":{"date-parts":[[2016,2,8]],"date-time":"2016-02-08T21:33:09Z","timestamp":1454967189000},"page":"868-876","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":96,"title":["Right ventricular afterload sensitivity dramatically increases after left ventricular assist device implantation: A multi-center hemodynamic analysis"],"prefix":"10.1016","volume":"35","author":[{"given":"Brian A.","family":"Houston","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohan J.","family":"Kalathiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Loungani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary E.","family":"Davis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel T.","family":"Coffin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Haglund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Maltais","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary E.","family":"Keebler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Leary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel P.","family":"Judge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerin R.","family":"Stevens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Rickard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris M.","family":"Sciortino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glenn J.","family":"Whitman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashish S.","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart D.","family":"Russell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan J.","family":"Tedford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.healun.2016.01.1225_bib1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/HCO.0b013e32835dd12c","article-title":"Right-ventricular failure following left ventricle assist device implantation","volume":"28","author":"Patlolla","year":"2013","journal-title":"Curr Opin Cardiol"},{"key":"10.1016\/j.healun.2016.01.1225_bib2","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1177\/026765910001500407","article-title":"Complications of circulatory assist","volume":"15","author":"El-Banayosy","year":"2000","journal-title":"Perfusion"},{"key":"10.1016\/j.healun.2016.01.1225_bib3","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1067\/mtc.2001.118274","article-title":"Multicenter clinical evaluation of the HeartMate vented electric left ventricular assist system in patients awaiting heart transplantation","volume":"122","author":"Frazier","year":"2001","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.healun.2016.01.1225_bib4","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/S0003-4975(01)03406-3","article-title":"Right ventricular dysfunction and organ failure in left ventricular assist device recipients: a continuing problem","volume":"73","author":"Kavarana","year":"2002","journal-title":"Ann Thorac Surg"},{"issue":"suppl I","key":"10.1016\/j.healun.2016.01.1225_bib5","article-title":"Predictors of severe right ventricular failure after implantable left ventricular assist device insertion: analysis of 245 patients","volume":"106","author":"Ochiai","year":"2002","journal-title":"Circulation"},{"issue":"suppl","key":"10.1016\/j.healun.2016.01.1225_bib6","doi-asserted-by":"crossref","first-page":"S29","DOI":"10.1016\/S0003-4975(03)00461-2","article-title":"Patient selection for left ventricular assist device therapy","volume":"75","author":"Aaronson","year":"2003","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.healun.2016.01.1225_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.healun.2005.07.008","article-title":"Right heart failure after left ventricular assist device implantation in patients with chronic congestive heart failure","volume":"25","author":"Dang","year":"2006","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2016.01.1225_bib8","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1016\/j.jacc.2008.03.009","article-title":"The right ventricular failure risk score a preoperative tool for assessing the risk of right ventricular failure in left ventricular assist device candidates","volume":"51","author":"Matthews","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.healun.2016.01.1225_bib9","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.healun.2010.09.006","article-title":"Right-to-left ventricular end diastolic diameter ratio and prediction of right ventricular failure with continuous-flow left ventricular assist devices","volume":"30","author":"Kukucka","year":"2011","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2016.01.1225_bib10","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.jacc.2012.02.073","article-title":"Independent and incremental role of quantitative right ventricular evaluation for the prediction of right ventricular failure after left ventricular assist device implantation","volume":"60","author":"Grant","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.healun.2016.01.1225_bib11","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1056\/NEJMoa0909938","article-title":"Advanced heart failure treated with continuous-flow left ventricular assist device","volume":"361","author":"Slaughter","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.healun.2016.01.1225_bib12","doi-asserted-by":"crossref","first-page":"M228","DOI":"10.1097\/00002480-199207000-00026","article-title":"Quantification of right ventricular shape changes after left ventricular assist device implantation","volume":"38","author":"Mandarino","year":"1992","journal-title":"ASAIO J"},{"key":"10.1016\/j.healun.2016.01.1225_bib13","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/0003-4975(93)90402-4","article-title":"Right ventricular dynamics during left ventricular assistance in closed-chest dogs","volume":"56","author":"Moon","year":"1993","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.healun.2016.01.1225_bib14","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/BF01656260","article-title":"Right heart interaction with the mechanically assisted left heart","volume":"9","author":"Farrar","year":"1985","journal-title":"World J Surg"},{"key":"10.1016\/j.healun.2016.01.1225_bib15","first-page":"163","article-title":"Ventricular interactions during mechanical circulatory support. Sem","volume":"6","author":"Farrar","year":"1994","journal-title":"Thorac Cardiovasc Surg"},{"key":"10.1016\/j.healun.2016.01.1225_bib16","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1016\/j.healun.2004.11.054","article-title":"Differential exercise performance on ventricular assist device support","volume":"24","author":"Simon","year":"2005","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2016.01.1225_bib17","doi-asserted-by":"crossref","first-page":"D42","DOI":"10.1016\/j.jacc.2013.10.032","article-title":"Definitions and diagnosis of pulmonary hypertension","volume":"62","author":"Hoeper","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.healun.2016.01.1225_bib18","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1053\/jcan.2002.128411","article-title":"Validation of continuous thermodilution cardiac output in patients implanted with a left ventricular assist device","volume":"16","author":"Mets","year":"2002","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10.1016\/j.healun.2016.01.1225_bib19","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1097\/MAT.0000000000000119","article-title":"Association of HeartMate II left ventricular assist device flow estimate with thermodilution cardiac output","volume":"60","author":"Hasin","year":"2014","journal-title":"ASAIO J"},{"key":"10.1016\/j.healun.2016.01.1225_bib20","first-page":"261","article-title":"Thermodilution and Fick cardiac outputs differ: impact on pulmonary hypertension evaluation","volume":"19","author":"Fares","year":"2012","journal-title":"Can Respir J"},{"key":"10.1016\/j.healun.2016.01.1225_bib21","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1164\/ajrccm.160.2.9811062","article-title":"Determination of cardiac output by the Fick method, thermodilution, and acetylene rebreathing in pulmonary hypertension","volume":"160","author":"Hoeper","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.healun.2016.01.1225_bib22","doi-asserted-by":"crossref","first-page":"H424","DOI":"10.1152\/ajpheart.1999.276.2.H424","article-title":"Use of pulse pressure method for estimating total arterial compliance in vivo","volume":"276","author":"Stergiopulos","year":"1999","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.healun.2016.01.1225_bib23","doi-asserted-by":"crossref","first-page":"H2736","DOI":"10.1152\/ajpheart.00796.2007","article-title":"Effective arterial elastance as an index of pulmonary vascular load","volume":"294","author":"Morimont","year":"2008","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.healun.2016.01.1225_bib24","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1136\/heartjnl-2014-306142","article-title":"RV-pulmonary arterial coupling predicts outcome in patients referred for pulmonary hypertension","volume":"101","author":"Vanderpool","year":"2015","journal-title":"Heart"},{"key":"10.1016\/j.healun.2016.01.1225_bib25","article-title":"Right ventricular effective arterial elastance is a novel predictor of mortality in pulmonary hypertension due to left heart disease. Abstract 16651 presented at the Scientific Sessions of the American","author":"Tampakakis","year":"2014","journal-title":"Heart Association"},{"key":"10.1016\/j.healun.2016.01.1225_bib26","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1016\/j.jtcvs.2009.11.020","article-title":"Right ventricular failure in patients with the HeartMate II continuous flow left ventricular assist device: incidence, risk factors, and effect on outcomes","volume":"139","author":"Kormos","year":"2010","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.healun.2016.01.1225_bib27","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1161\/CIRCHEARTFAILURE.112.000204","article-title":"Relationship of right- to left-sided ventricular filling pressures in advanced heart failure: insights from the ESCAPE trial. Circ","volume":"6","author":"Drazner","year":"2013","journal-title":"Heart Fail"},{"key":"10.1016\/j.healun.2016.01.1225_bib28","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1016\/S0022-5223(19)38725-2","article-title":"Interaction of right and left ventricular filling pressures at the termination of cardiopulmonary bypass. Central venous pressure\/pulmonary capillary wedge pressure ratio","volume":"89","author":"Kopman","year":"1985","journal-title":"Thorac Cardiovasc Surg"},{"key":"10.1016\/j.healun.2016.01.1225_bib29","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1001\/jama.294.13.1625","article-title":"Evaluation study of congestive heart failure and pulmonary artery catheterization effectiveness: the ESCAPE trial","volume":"294","author":"Binanay","year":"2005","journal-title":"JAMA"},{"key":"10.1016\/j.healun.2016.01.1225_bib30","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.healun.2011.09.003","article-title":"Relationship of right- and left-sided filling pressures in patients with advanced heart failure: a 14-year multi-institutional analysis","volume":"31","author":"Drazner","year":"2012","journal-title":"J Heart Lung Transplant"},{"issue":"suppl","key":"10.1016\/j.healun.2016.01.1225_bib31","first-page":"II316","article-title":"Right ventricular\/arterial coupling in the patient with left ventricular assistance","volume":"86","author":"Morita","year":"1992","journal-title":"Circulation"},{"key":"10.1016\/j.healun.2016.01.1225_bib32","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.healun.2009.09.013","article-title":"Pulsatile left ventricular assist device support as a bridge to decision in patients with end-stage heart failure complicated by pulmonary hypertension","volume":"29","author":"Nair","year":"2010","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2016.01.1225_bib33","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.healun.2009.11.599","article-title":"Effects of the HeartMate II continuous-flow left ventricular assist device on right ventricular function","volume":"29","author":"Lee","year":"2010","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2016.01.1225_bib34","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.healun.2012.12.018","article-title":"Impact of continuous-flow left ventricular assist device support on right ventricular function","volume":"32","author":"Morgan","year":"2013","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2016.01.1225_bib35","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.cardfail.2014.04.017","article-title":"Right ventricular systolic and diastolic function as assessed by speckle-tracking echocardiography improve with prolonged isolated left ventricular assist device support","volume":"20","author":"Herod","year":"2014","journal-title":"J Card Fail"},{"key":"10.1016\/j.healun.2016.01.1225_bib36","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.healun.2013.05.004","article-title":"Marked changes in right ventricular contractile pattern after cardiothoracic surgery: implications for post-surgical assessment of right ventricular function","volume":"32","author":"Raina","year":"2013","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2016.01.1225_bib37","first-page":"971","article-title":"Reversibility of fixed pulmonary hypertension in left ventricular assist device support recipients","volume":"40","author":"Mikus","year":"2011","journal-title":"Eur J Cardiothorac Surg"},{"issue":"suppl 1","key":"10.1016\/j.healun.2016.01.1225_bib38","first-page":"S14","article-title":"Load dependency of right ventricular performance is a major factor to be considered in decision making before ventricular assist device implantation","volume":"128","author":"Dandel","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.healun.2016.01.1225_bib39","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1378\/chest.10-1136","article-title":"Longitudinal shortening accounts for the majority of right ventricular contraction and improves after pulmonary vasodilator therapy in normal subjects and patients with pulmonary arterial hypertension","volume":"140","author":"Brown","year":"2011","journal-title":"Chest"},{"issue":"suppl 1","key":"10.1016\/j.healun.2016.01.1225_bib40","doi-asserted-by":"crossref","first-page":"S272","DOI":"10.1016\/j.ejcts.2006.02.011","article-title":"The ventricular septum: the lion of right ventricular function, and its impact on right ventricular restoration","volume":"29","author":"Buckberg","year":"2006","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.healun.2016.01.1225_bib41","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1161\/CIRCULATIONAHA.111.051540","article-title":"Pulmonary capillary wedge pressure augments right ventricular pulsatile loading","volume":"125","author":"Tedford","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.healun.2016.01.1225_bib42","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1161\/CIRCHEARTFAILURE.112.968511","article-title":"Prognostic role of pulmonary arterial capacitance in advanced heart failure. Circ","volume":"5","author":"Dupont","year":"2012","journal-title":"Heart Fail"},{"key":"10.1016\/j.healun.2016.01.1225_bib43","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1378\/chest.13-1510","article-title":"Prognostic relevance of pulmonary arterial compliance in patients with chronic heart failure","volume":"145","author":"Pellegrini","year":"2014","journal-title":"Chest"},{"key":"10.1016\/j.healun.2016.01.1225_bib44","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.healun.2014.05.016","article-title":"A minimally invasive off-pump implantation technique for continuous-flow left ventricular assist devices: early experience","volume":"33","author":"Strueber","year":"2014","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2016.01.1225_bib45","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1053\/j.jvca.2014.11.007","article-title":"Minimally invasive thoracic left ventricular assist device implantation; case series demonstrating an integrated multidisciplinary strategy","volume":"29","author":"Wagner","year":"2015","journal-title":"J Cardiothorac Vasc Anesth"}],"container-title":["The Journal of Heart and Lung Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053249816012791?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053249816012791?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T08:32:27Z","timestamp":1760949147000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1053249816012791"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":45,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["S1053249816012791"],"URL":"https:\/\/doi.org\/10.1016\/j.healun.2016.01.1225","relation":{},"ISSN":["1053-2498"],"issn-type":[{"value":"1053-2498","type":"print"}],"subject":[],"published":{"date-parts":[[2016,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Right ventricular afterload sensitivity dramatically increases after left ventricular assist device implantation: A multi-center hemodynamic analysis","name":"articletitle","label":"Article Title"},{"value":"The Journal of Heart and Lung Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.healun.2016.01.1225","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 International Society for the Heart and Lung Transplantation. Published by International Society for the Heart and Lung Transplantation All rights reserved.","name":"copyright","label":"Copyright"}]}}