{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:09:37Z","timestamp":1782864577392,"version":"3.54.5"},"reference-count":30,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jhltonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Heart and Lung Transplantation"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.healun.2022.06.005","type":"journal-article","created":{"date-parts":[[2022,7,23]],"date-time":"2022-07-23T01:46:02Z","timestamp":1658540762000},"page":"1391-1400","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Venovenous extracorporeal membrane oxygenation promotes alveolar epithelial recovery by activating Hippo\/YAP signaling after lung injury"],"prefix":"10.1016","volume":"41","author":[{"given":"Jian","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongzhi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerong","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shilin","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingdong","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianbao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingren","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangyang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0821-8875","authenticated-orcid":false,"given":"Yongnan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.healun.2022.06.005_bib0001","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1001\/jama.2017.21907","article-title":"Acute respiratory distress syndrome: advances in diagnosis and treatment","volume":"319","author":"Fan","year":"2018","journal-title":"JAMA"},{"key":"10.1016\/j.healun.2022.06.005_bib0002","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.chest.2021.08.041","article-title":"Lung transplantation for patients with COVID-19","volume":"161","author":"King","year":"2022","journal-title":"Chest"},{"key":"10.1016\/j.healun.2022.06.005_bib0003","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S2213-2600(18)30452-1","article-title":"Venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis","volume":"7","author":"Munshi","year":"2019","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.healun.2022.06.005_bib0004","first-page":"e5365","article-title":"Venovenous extracorporeal membrane oxygenation therapy in adults","volume":"11","author":"Patel","year":"2019","journal-title":"Cureus"},{"key":"10.1016\/j.healun.2022.06.005_bib0005","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1097\/ALN.0000000000003221","article-title":"Extracorporeal membrane oxygenation for respiratory failure","volume":"132","author":"Quintel","year":"2020","journal-title":"Anesthesiology"},{"key":"10.1016\/j.healun.2022.06.005_bib0006","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1097\/CCM.0000000000003894","article-title":"Ultra-Protective ventilation reduces biotrauma in patients on venovenous extracorporeal membrane oxygenation for severe acute respiratory distress syndrome","volume":"47","author":"Rozencwajg","year":"2019","journal-title":"Crit Care Med"},{"key":"10.1016\/j.healun.2022.06.005_bib0007","article-title":"Establishment of a venovenous extracorporeal membrane oxygenation in a rat model of acute respiratory distress syndrome","author":"Li","year":"2021","journal-title":"Perfusion"},{"key":"10.1016\/j.healun.2022.06.005_bib0008","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1097\/CCM.0b013e31816a0607","article-title":"Protective effects of propofol on acute lung injury induced by oleic acid in conscious rats","volume":"36","author":"Chen","year":"2008","journal-title":"Crit Care Med"},{"key":"10.1016\/j.healun.2022.06.005_bib0009","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/260465","article-title":"Acute respiratory distress syndrome: Role of oleic acid-triggered lung injury and inflammation","volume":"2015","author":"Gon\u00e7alves-de-Albuquerque","year":"2015","journal-title":"Mediators Inflamm"},{"key":"10.1016\/j.healun.2022.06.005_bib0010","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.jhep.2019.05.029","article-title":"Activation of YAP attenuates hepatic damage and fibrosis in liver ischemia-reperfusion injury","volume":"71","author":"Liu","year":"2019","journal-title":"J Hepatol"},{"key":"10.1016\/j.healun.2022.06.005_bib0011","doi-asserted-by":"crossref","first-page":"3188","DOI":"10.3390\/ijms21093188","article-title":"Mechanisms of ATII-to-ATI Cell differentiation during lung regeneration","volume":"21","author":"Aspal","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.healun.2022.06.005_bib0012","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.cell.2019.11.027","article-title":"Progressive pulmonary fibrosis is caused by elevated mechanical tension on alveolar stem cells","volume":"180","author":"Wu","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.healun.2022.06.005_bib0013","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.stem.2020.06.020","article-title":"Inflammatory signals induce AT2 cell-derived damage-associated transient progenitors that mediate alveolar regeneration","volume":"27","author":"Choi","year":"2020","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.healun.2022.06.005_bib0014","doi-asserted-by":"crossref","first-page":"3559","DOI":"10.1038\/s41467-020-17358-3","article-title":"Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis","volume":"11","author":"Strunz","year":"2020","journal-title":"Nat Commun"},{"key":"10.1016\/j.healun.2022.06.005_bib0015","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.1172\/JCI125014","article-title":"Yap\/Taz regulate alveolar regeneration and resolution of lung inflammation","volume":"129","author":"LaCanna","year":"2019","journal-title":"J Clin Invest"},{"key":"10.1016\/j.healun.2022.06.005_bib0016","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1165\/rcmb.2017-0037MA","article-title":"Unbiased quantitation of alveolar type II to alveolar type I cell transdifferentiation during repair after lung injury in mice","volume":"57","author":"Jansing","year":"2017","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.healun.2022.06.005_bib0017","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/s41580-018-0086-y","article-title":"Hippo-YAP\/TAZ signalling in organ regeneration and regenerative medicine","volume":"20","author":"Moya","year":"2019","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.healun.2022.06.005_bib0018","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1101\/gad.1865310","article-title":"Structural basis of YAP recognition by TEAD4 in the hippo pathway","volume":"24","author":"Chen","year":"2010","journal-title":"Genes Dev"},{"key":"10.1016\/j.healun.2022.06.005_bib0019","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1002\/cbin.11098","article-title":"The Hippo-YAP pathway regulates the proliferation of alveolar epithelial progenitors after acute lung injury","volume":"43","author":"Hu","year":"2019","journal-title":"Cell Biol Int"},{"key":"10.1016\/j.healun.2022.06.005_bib0020","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1001\/jama.2019.9302","article-title":"Extracorporeal life support for adults with respiratory failure and related indications: a review","volume":"322","author":"Brodie","year":"2019","journal-title":"JAMA"},{"key":"10.1016\/j.healun.2022.06.005_bib0021","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1016\/j.healun.2018.07.003","article-title":"Intraoperative extracorporeal support during lung transplantation in patients bridged with venovenous extracorporeal membrane oxygenation","volume":"37","author":"Hashimoto","year":"2018","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2022.06.005_bib0022","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/ajt.16759","article-title":"Lung transplantation for acute respiratory distress syndrome: A multicenter experience","volume":"22","author":"Frick","year":"2022","journal-title":"Am J Transplant"},{"key":"10.1016\/j.healun.2022.06.005_bib0023","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/aor.13827","article-title":"Advances in extracorporeal membrane oxygenator design for artificial placenta technology","volume":"45","author":"Blauvelt","year":"2021","journal-title":"Artif Organs"},{"key":"10.1016\/j.healun.2022.06.005_bib0024","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1007\/s00134-012-2785-8","article-title":"Blood oxygenation and decarboxylation determinants during venovenous ECMO for respiratory failure in adults","volume":"39","author":"Schmidt","year":"2013","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.healun.2022.06.005_bib0025","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1038\/s41572-019-0069-0","article-title":"Acute respiratory distress syndrome","volume":"5","author":"Matthay","year":"2019","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.healun.2022.06.005_bib0026","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1183\/09031936.04.00096003","article-title":"The use of alveolar epithelial type I cell-selective markers to investigate lung injury and repair","volume":"24","author":"McElroy","year":"2004","journal-title":"Eur Respir J"},{"key":"10.1016\/j.healun.2022.06.005_bib0027","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1186\/s12931-016-0480-y","article-title":"The cellular kinetics of lung alveolar epithelial cells and its relationship with lung tissue repair after acute lung injury","volume":"17","author":"Zeng","year":"2016","journal-title":"Respir Res"},{"key":"10.1016\/j.healun.2022.06.005_bib0028","first-page":"2826","article-title":"Extracorporeal membrane oxygenation improves survival in a novel 24-hour pig model of severe acute respiratory distress syndrome","volume":"8","author":"Araos","year":"2016","journal-title":"Am J Transl Res"},{"key":"10.1016\/j.healun.2022.06.005_bib0029","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/s41422-020-0369-7","article-title":"Pulmonary alveolar regeneration in adult COVID-19 patients","volume":"30","author":"Chen","year":"2020","journal-title":"Cell Res"},{"key":"10.1016\/j.healun.2022.06.005_bib0030","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.04165-2020","article-title":"Collapse induration of alveoli is an ultrastructural finding in a COVID-19 patient","volume":"57","author":"Ochs","year":"2021","journal-title":"Eur Respir J"}],"container-title":["The Journal of Heart and Lung Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053249822019842?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053249822019842?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T08:46:54Z","timestamp":1760950014000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1053249822019842"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":30,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["S1053249822019842"],"URL":"https:\/\/doi.org\/10.1016\/j.healun.2022.06.005","relation":{},"ISSN":["1053-2498"],"issn-type":[{"value":"1053-2498","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Venovenous extracorporeal membrane oxygenation promotes alveolar epithelial recovery by activating Hippo\/YAP signaling after lung injury","name":"articletitle","label":"Article Title"},{"value":"The Journal of Heart and Lung Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.healun.2022.06.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 International Society for Heart and Lung Transplantation. All rights reserved.","name":"copyright","label":"Copyright"}]}}