{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T21:08:55Z","timestamp":1793653735570,"version":"4.5.1"},"reference-count":37,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,15]],"date-time":"2024-02-15T00:00:00Z","timestamp":1707955200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010564","name":"Deutsches Zentrum fur Lungenforschung e V","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010564","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jhltonline.org","clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Heart and Lung Transplantation"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.healun.2024.02.013","type":"journal-article","created":{"date-parts":[[2024,2,17]],"date-time":"2024-02-17T16:35:35Z","timestamp":1708187735000},"page":"1105-1115","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Liver stiffness is associated with right heart dysfunction, cardiohepatic syndrome, and prognosis in pulmonary hypertension"],"prefix":"10.1016","volume":"43","author":[{"given":"Zvonimir A.","family":"Rako","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9505-8608","authenticated-orcid":false,"given":"Athiththan","family":"Yogeswaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selin","family":"Yildiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Weidemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Zedler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno Brito","family":"da Rocha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5683-4990","authenticated-orcid":false,"given":"Vitalii","family":"Kryvenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Sch\u00e4fer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossein Ardeschir","family":"Ghofrani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1946-0894","authenticated-orcid":false,"given":"Werner","family":"Seeger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils C.","family":"Kremer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khodr","family":"Tello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.healun.2024.02.013_bib1","doi-asserted-by":"crossref","first-page":"2200879","DOI":"10.1183\/13993003.00879-2022","article-title":"2022 ESC\/ERS guidelines for the diagnosis and treatment of pulmonary hypertension","volume":"61","author":"Humbert","year":"2023","journal-title":"Eur Respir J"},{"key":"10.1016\/j.healun.2024.02.013_bib2","doi-asserted-by":"crossref","first-page":"1801900","DOI":"10.1183\/13993003.01900-2018","article-title":"Pathophysiology of the right ventricle and of the pulmonary circulation in pulmonary hypertension: an update","volume":"53","author":"Vonk Noordegraaf","year":"2019","journal-title":"Eur Respir J"},{"key":"10.1016\/j.healun.2024.02.013_bib3","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1183\/09059180.00006511","article-title":"The role of the right ventricle in pulmonary arterial hypertension","volume":"20","author":"Vonk Noordegraaf","year":"2011","journal-title":"Eur Respir Rev"},{"key":"10.1016\/j.healun.2024.02.013_bib4","doi-asserted-by":"crossref","first-page":"1900625","DOI":"10.1183\/13993003.00625-2019","article-title":"Vena cava backflow and right ventricular stiffness in pulmonary arterial hypertension","volume":"54","author":"Marcus","year":"2019","journal-title":"Eur Respir J"},{"key":"10.1016\/j.healun.2024.02.013_bib5","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1161\/CIRCULATIONAHA.116.022362","article-title":"Systemic consequences of pulmonary hypertension and right-sided heart failure","volume":"141","author":"Rosenkranz","year":"2020","journal-title":"Circulation"},{"key":"10.1016\/j.healun.2024.02.013_bib6","first-page":"30","article-title":"Prognostic value of liver and spleen stiffness in patients with fontan associated liver disease (FALD): a case series with histopathologic comparison","volume":"8","author":"Padalino","year":"2021","journal-title":"J Cardiovasc Dev Dis"},{"key":"10.1016\/j.healun.2024.02.013_bib7","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.healun.2021.10.018","article-title":"Risk assessment in pulmonary hypertension based on routinely measured laboratory parameters","volume":"41","author":"Yogeswaran","year":"2022","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2024.02.013_bib8","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.jcin.2021.10.033","article-title":"Cardiohepatic syndrome is associated with poor prognosis in patients undergoing tricuspid transcatheter edge-to-edge valve repair","volume":"15","author":"Stolz","year":"2022","journal-title":"JACC Cardiovasc Inter"},{"key":"10.1016\/j.healun.2024.02.013_bib9","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s11897-014-0238-0","article-title":"Cardiohepatic syndrome","volume":"12","author":"Poelzl","year":"2015","journal-title":"Curr Heart Fail Rep"},{"key":"10.1016\/j.healun.2024.02.013_bib10","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1007\/s11897-014-0206-8","article-title":"Cardiohepatic syndrome: liver injury in decompensated heart failure","volume":"11","author":"Laribi","year":"2014","journal-title":"Curr Heart Fail Rep"},{"key":"10.1016\/j.healun.2024.02.013_bib11","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.1016\/j.ultrasmedbio.2018.07.008","article-title":"Liver ultrasound elastography: an update to the world federation for ultrasound in medicine and biology guidelines and recommendations","volume":"44","author":"Ferraioli","year":"2018","journal-title":"Ultrasound Med Biol"},{"key":"10.1016\/j.healun.2024.02.013_bib12","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1016\/j.jcmg.2018.12.032","article-title":"Cardiac magnetic resonance imaging-based right ventricular strain analysis for assessment of coupling and diastolic function in pulmonary hypertension","volume":"12","author":"Tello","year":"2019","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.healun.2024.02.013_bib13","doi-asserted-by":"crossref","DOI":"10.1177\/2045893217742000","article-title":"Non-invasive imaging of global and regional cardiac function in pulmonary hypertension","volume":"8","author":"Crowe","year":"2018","journal-title":"Pulm Circ"},{"key":"10.1016\/j.healun.2024.02.013_bib14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0038519","article-title":"Diagnostic value of echocardiography in the diagnosis of pulmonary hypertension","volume":"7","author":"Hammerstingl","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.healun.2024.02.013_bib15","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.7150\/thno.18650","article-title":"Ultrasound elastography: review of techniques and clinical applications","volume":"7","author":"Sigrist","year":"2017","journal-title":"Theranostics"},{"key":"10.1016\/j.healun.2024.02.013_bib16","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1055\/s-0042-117226","article-title":"Shear wave elastography of the liver - review on normal values","volume":"55","author":"Dong","year":"2017","journal-title":"Z Gastroenterol"},{"key":"10.1016\/j.healun.2024.02.013_bib17","doi-asserted-by":"crossref","first-page":"1901892","DOI":"10.1183\/13993003.01892-2019","article-title":"Evaluation of pulmonary hypertension by right heart catheterisation: does timing matter?","volume":"56","author":"Yogeswaran","year":"2020","journal-title":"Eur Respir J"},{"key":"10.1016\/j.healun.2024.02.013_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.echo.2014.10.003","article-title":"Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging","volume":"28","author":"Lang","year":"2015","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.healun.2024.02.013_bib19","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1093\/ehjci\/jeaa126","article-title":"How to do right ventricular strain","volume":"21","author":"Badano","year":"2020","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.healun.2024.02.013_bib20","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1111\/echo.12773","article-title":"Spectral Doppler of the hepatic veins in tricuspid valve disease","volume":"32","author":"Fadel","year":"2015","journal-title":"Echocardiography"},{"key":"10.1016\/j.healun.2024.02.013_bib21","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1111\/echo.13091","article-title":"Spectral Doppler of the hepatic veins in rate, rhythm, and conduction disorders","volume":"33","author":"Fadel","year":"2016","journal-title":"Echocardiography"},{"key":"10.1016\/j.healun.2024.02.013_bib22","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1055\/s-0043-103955","article-title":"EFSUMB guidelines and recommendations on the clinical use of liver ultrasound elastography, update 2017 (short version)","volume":"38","author":"Dietrich","year":"2017","journal-title":"Ultraschall Med"},{"key":"10.1016\/j.healun.2024.02.013_bib23","doi-asserted-by":"crossref","DOI":"10.1177\/17562848221140657","article-title":"Update on the role of elastography in liver disease","volume":"15","author":"Ferraioli","year":"2022","journal-title":"Ther Adv Gastroenterol"},{"key":"10.1016\/j.healun.2024.02.013_bib24","doi-asserted-by":"crossref","DOI":"10.1056\/NEJMicm1901205","article-title":"Hepatopulmonary syndrome","volume":"382","author":"Kumar","year":"2020","journal-title":"N Engl J Med"},{"key":"10.1016\/j.healun.2024.02.013_bib25","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.4254\/wjh.v13.i9.1058","article-title":"Liver kidney crosstalk: hepatorenal syndrome","volume":"13","author":"Nassar","year":"2021","journal-title":"World J Hepatol"},{"key":"10.1016\/j.healun.2024.02.013_bib26","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1053\/j.ackd.2018.08.004","article-title":"Cardiorenal syndrome: an overview","volume":"25","author":"Ronco","year":"2018","journal-title":"Adv Chronic Kidney Dis"},{"key":"10.1016\/j.healun.2024.02.013_bib27","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1097\/TP.0000000000001229","article-title":"International liver transplant society practice guidelines: diagnosis and management of hepatopulmonary syndrome and portopulmonary hypertension","volume":"100","author":"Krowka","year":"2016","journal-title":"Transplantation"},{"key":"10.1016\/j.healun.2024.02.013_bib28","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1183\/09031936.00156714","article-title":"Clinical relevance of right ventricular diastolic stiffness in pulmonary hypertension","volume":"45","author":"Trip","year":"2015","journal-title":"Eur Respir J"},{"key":"10.1016\/j.healun.2024.02.013_bib29","doi-asserted-by":"crossref","first-page":"H156","DOI":"10.1152\/ajpheart.00485.2019","article-title":"Right ventricular function correlates of right atrial strain in pulmonary hypertension: a combined cardiac magnetic resonance and conductance catheter study","volume":"318","author":"Tello","year":"2020","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.healun.2024.02.013_bib30","doi-asserted-by":"crossref","first-page":"2101454","DOI":"10.1183\/13993003.01454-2021","article-title":"Right atrial function is associated with right venticular diastolic stiffness: RA-RV interaction in pulmonary arterial hypertension","volume":"59","author":"Wessels","year":"2022","journal-title":"Eur Respir J"},{"key":"10.1016\/j.healun.2024.02.013_bib31","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/j.jcmg.2017.10.022","article-title":"Liver stiffness reflecting right-sided filling pressure can predict adverse outcomes in patients with heart failure","volume":"12","author":"Taniguchi","year":"2019","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.healun.2024.02.013_bib32","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1007\/s00380-021-01951-7","article-title":"Liver fibrosis index as a novel prognostic factor in patients with pulmonary arterial hypertension","volume":"37","author":"Furukawa","year":"2022","journal-title":"Heart Vessels"},{"key":"10.1016\/j.healun.2024.02.013_bib33","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1536\/ihj.22-574","article-title":"Shear wave dispersion slope of the liver can predict adverse outcomes in patients with pulmonary hypertension","volume":"64","author":"Urabe","year":"2023","journal-title":"Int Heart J"},{"key":"10.1016\/j.healun.2024.02.013_bib34","doi-asserted-by":"crossref","first-page":"1800248","DOI":"10.1183\/13993003.00248-2018","article-title":"Risk assessment in medically treated chronic thromboembolic pulmonary hypertension patients","volume":"52","author":"Delcroix","year":"2018","journal-title":"Eur Respir J"},{"key":"10.1016\/j.healun.2024.02.013_bib35","doi-asserted-by":"crossref","first-page":"4175","DOI":"10.1093\/eurheartj\/ehx257","article-title":"A comprehensive risk stratification at early follow-up determines prognosis in pulmonary arterial hypertension","volume":"39","author":"Kylhammar","year":"2018","journal-title":"Eur Heart J"},{"key":"10.1016\/j.healun.2024.02.013_bib36","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1016\/j.healun.2020.06.014","article-title":"Risk assessment in severe pulmonary hypertension due to interstitial lung disease","volume":"39","author":"Yogeswaran","year":"2020","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2024.02.013_bib37","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2021.748173","article-title":"Correlation between liver stiffness and diastolic function, left ventricular hypertrophy, and right cardiac function in patients with ejection fraction preserved heart failure","volume":"8","author":"Zhang","year":"2021","journal-title":"Front Cardiovasc Med"}],"container-title":["The Journal of Heart and Lung Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053249824000561?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053249824000561?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T10:31:00Z","timestamp":1728988260000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1053249824000561"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":37,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["S1053249824000561"],"URL":"https:\/\/doi.org\/10.1016\/j.healun.2024.02.013","relation":{},"ISSN":["1053-2498"],"issn-type":[{"value":"1053-2498","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Liver stiffness is associated with right heart dysfunction, cardiohepatic syndrome, and prognosis in pulmonary hypertension","name":"articletitle","label":"Article Title"},{"value":"The Journal of Heart and Lung Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.healun.2024.02.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc. on behalf of International Society for Heart and Lung Transplantation.","name":"copyright","label":"Copyright"}]}}