{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T01:41:56Z","timestamp":1789695716417,"version":"4.0.1"},"reference-count":27,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["jhltonline.org","clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Heart and Lung Transplantation"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.healun.2024.06.003","type":"journal-article","created":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T12:04:43Z","timestamp":1719403483000},"page":"1668-1676","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Right ventricular phenotyping in incident patients with idiopathic pulmonary arterial hypertension"],"prefix":"10.1016","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1858-1152","authenticated-orcid":false,"given":"Stefano","family":"Ghio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7887-5961","authenticated-orcid":false,"given":"Roberto","family":"Badagliacca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"D\u2019Alto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Scelsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Argiento","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natale D.","family":"Brunetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gavino","family":"Casu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Cedrone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4791-768X","authenticated-orcid":false,"given":"Marco","family":"Confalonieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Corda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Correale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"D\u2019Agostino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabetta","family":"De Tommasi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1515-506X","authenticated-orcid":false,"given":"Domenico","family":"Filomena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Galgano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Greco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Grimaldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Lombardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosalinda","family":"Madonna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanna","family":"Manzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9448-2762","authenticated-orcid":false,"given":"Valentina","family":"Mercurio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Mihai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimiliano","family":"Mul\u00e8","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Paciocco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8653-4035","authenticated-orcid":false,"given":"Silvia","family":"Papa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6434-1352","authenticated-orcid":false,"given":"Tommaso","family":"Recchioni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonella","family":"Romaniello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuele","family":"Romeo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4538-6811","authenticated-orcid":false,"given":"Davide","family":"Stolfo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrizio","family":"Vitulo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9627-6236","authenticated-orcid":false,"given":"Raymond L.","family":"Benza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3540-4983","authenticated-orcid":false,"given":"Carmine D.","family":"Vizza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.healun.2024.06.003_bib1","doi-asserted-by":"crossref","first-page":"3618","DOI":"10.1093\/eurheartj\/ehac237","article-title":"2022 ESC\/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension","volume":"43","author":"Humbert","year":"2022","journal-title":"Eur Heart J"},{"key":"10.1016\/j.healun.2024.06.003_bib2","doi-asserted-by":"crossref","first-page":"343","DOI":"10.7326\/0003-4819-115-5-343","article-title":"Survival in patients with primary pulmonary hypertension","volume":"115","author":"D\u2019Alonzo","year":"1991","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.healun.2024.06.003_bib3","doi-asserted-by":"crossref","first-page":"4175","DOI":"10.1093\/eurheartj\/ehx257","article-title":"A comprehensive risk stratification at early follow-up determines prognosis in pulmonary arterial hypertension","volume":"39","author":"Kylhammar","year":"2018","journal-title":"Eur Heart J"},{"key":"10.1016\/j.healun.2024.06.003_bib4","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.02419-2021","article-title":"External validation of a refined 4-strata risk assessment score from the French pulmonary hypertension registry","volume":"59","author":"Boucly","year":"2022","journal-title":"Eur Respir J"},{"key":"10.1016\/j.healun.2024.06.003_bib5","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.02311-2021","article-title":"COMPERA 2.0: a refined 4-strata risk assessment model for pulmonary arterial hypertension","volume":"60","author":"Hoeper","year":"2022","journal-title":"Eur Respir J"},{"key":"10.1016\/j.healun.2024.06.003_bib6","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.chest.2019.02.004","article-title":"Predicting survival in patients with pulmonary arterial hypertension: the REVEAL Risk Score Calculator 2.0 and comparison with ESC\/ERS-based risk assessment strategies","volume":"156","author":"Benza","year":"2019","journal-title":"Chest"},{"key":"10.1016\/j.healun.2024.06.003_bib7","doi-asserted-by":"crossref","DOI":"10.1177\/2045894020961739","article-title":"Advanced risk stratification of intermediate risk group in pulmonary arterial hypertension","volume":"10","author":"Yogeswaran","year":"2020","journal-title":"Pulm Circ"},{"key":"10.1016\/j.healun.2024.06.003_bib8","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1016\/j.healun.2022.09.005","article-title":"Interest of TAPSE\/sPAP ratio for noninvasive pulmonary arterial hypertension risk assessment","volume":"41","author":"Fauvel","year":"2022","journal-title":"J Heart Lung Transpl"},{"key":"10.1016\/j.healun.2024.06.003_bib9","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.1185\/03007995.2014.960514","article-title":"\u2018\u2018Real-life\u2019\u2019 information on pulmonary arterial hypertension: the iPHnet Project","volume":"30","author":"Poscia","year":"2014","journal-title":"Curr Med Res Opin"},{"key":"10.1016\/j.healun.2024.06.003_bib10","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.echo.2010.05.010","volume":"23","author":"Rudski","year":"2010","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.healun.2024.06.003_bib11","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.healun.2017.08.009","article-title":"Influence of various therapeutic strategies on right ventricular morphology, function and hemodynamics in pulmonary arterial hypertension","volume":"37","author":"Badagliacca","year":"2018","journal-title":"J Heart Lung Transpl"},{"key":"10.1016\/j.healun.2024.06.003_bib12","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1007\/s11897-023-00599-w","article-title":"Tricuspid regurgitation: right ventricular volume vs pressure load","volume":"20","author":"Naeije","year":"2023","journal-title":"Curr Heart Fail Rep"},{"key":"10.1016\/j.healun.2024.06.003_bib13","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1152\/japplphysiol.00081.2023","article-title":"How to incorporate tricuspid regurgitation in right ventricular-pulmonary arterial coupling","volume":"135","author":"Yoshida","year":"2023","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.healun.2024.06.003_bib14","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.chest.2019.02.004","article-title":"Predicting survival in patients with pulmonary arterial hypertension: the REVEAL Risk Score Calculator 2.0 and comparison with ESC\/ERS-based risk assessment strategies","volume":"156","author":"Benza","year":"2019","journal-title":"Chest"},{"key":"10.1016\/j.healun.2024.06.003_bib15","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1183\/09031936.00072212","article-title":"Resting heart rate is a predictor of mortality in COPD","volume":"42","author":"Jensen","year":"2013","journal-title":"Eur Respir J"},{"key":"10.1016\/j.healun.2024.06.003_bib16","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1161\/CIRCULATIONAHA.117.029901","article-title":"D-Dimer predicts long-term cause-specific mortality, cardiovascular events, and cancer in patients with stable coronary heart disease: LIPID study","volume":"138","author":"Simes","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.healun.2024.06.003_bib17","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s41512-018-0037-2","article-title":"Quantifying the added value of new biomarkers: how and how not","volume":"2","author":"Cook","year":"2018","journal-title":"Diagn Progn Res"},{"key":"10.1016\/j.healun.2024.06.003_bib18","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1007\/s10439-013-0752-3","article-title":"Methods for measuring right ventricular function and hemodynamic coupling with the pulmonary vasculature","volume":"41","author":"Bellofiore","year":"2013","journal-title":"Ann Biomed Eng"},{"key":"10.1016\/j.healun.2024.06.003_bib19","doi-asserted-by":"crossref","first-page":"e15","DOI":"10.1164\/rccm.201806-1160ST","article-title":"Assessment of right ventricular function in the research setting: knowledge gaps and pathways forward. An Official American Thoracic Society Research Statement","volume":"198","author":"Lahm","year":"2018","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.healun.2024.06.003_bib20","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1016\/j.jacc.2018.12.076","article-title":"Anatomy, function, and dysfunction of the right ventricle: state-of-the-art review","volume":"73","author":"Sanz","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.healun.2024.06.003_bib21","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.01900-2018","article-title":"Pathophysiology of the right ventricle and of the pulmonary circulation in pulmonary hypertension: an update","volume":"53","author":"Vonk Noordegraaf","year":"2019","journal-title":"Eur Respir J"},{"key":"10.1016\/j.healun.2024.06.003_bib22","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.ijcard.2008.11.051","article-title":"Prognostic relevance of the echocardiographic assessment of right ventricular function in patients with idiopathic pulmonary arterial hypertension","volume":"140","author":"Ghio","year":"2010","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.healun.2024.06.003_bib23","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.00513-2020","article-title":"A comprehensive echocardiographic method for risk stratification in pulmonary arterial hypertension","volume":"56","author":"Ghio","year":"2020","journal-title":"Eur Respir J"},{"key":"10.1016\/j.healun.2024.06.003_bib24","doi-asserted-by":"crossref","first-page":"00587-2023","DOI":"10.1183\/23120541.00587-2023","article-title":"Prognostic value of deep echocardiographic phenotyping in pulmonary arterial hypertension","volume":"10","author":"Ghio","year":"2024","journal-title":"ERJ Open Res"},{"key":"10.1016\/j.healun.2024.06.003_bib25","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1161\/CIRCULATIONAHA.117.029254","article-title":"Prognostic value of follow-up hemodynamic variables after initial management in pulmonary arterial hypertension","volume":"137","author":"Weatherald","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.healun.2024.06.003_bib26","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.healun.2017.09.026","article-title":"Prognostic relevance of right heart reverse remodeling in idiopathic pulmonary arterial hypertension","volume":"37","author":"Badagliacca","year":"2018","journal-title":"J Heart Lung Transpl"},{"key":"10.1016\/j.healun.2024.06.003_bib27","doi-asserted-by":"crossref","DOI":"10.1164\/rccm.202402-0431LE","article-title":"Relevance of echocardiography-derived phenotyping in pulmonary arterial hypertension patients treated with initial oral combination therapy","author":"Badagliacca","year":"2024","journal-title":"Am J Respir Crit Care Med"}],"container-title":["The Journal of Heart and Lung Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S105324982401698X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S105324982401698X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T05:27:21Z","timestamp":1728365241000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S105324982401698X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":27,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["S105324982401698X"],"URL":"https:\/\/doi.org\/10.1016\/j.healun.2024.06.003","relation":{},"ISSN":["1053-2498"],"issn-type":[{"value":"1053-2498","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Right ventricular phenotyping in incident patients with idiopathic pulmonary arterial hypertension","name":"articletitle","label":"Article Title"},{"value":"The Journal of Heart and Lung Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.healun.2024.06.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 International Society for Heart and Lung Transplantation. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}