{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T20:48:08Z","timestamp":1792010888814,"version":"4.4.0"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:00:00Z","timestamp":1789084800000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","award":["NIHR203332"],"award-info":[{"award-number":["NIHR203332"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jhltonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Heart and Lung Transplantation"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.healun.2026.09.006","type":"journal-article","created":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T15:16:49Z","timestamp":1789226209000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Investigating the impact of donor brain death duration on outcomes after lung transplant"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-6017-4478","authenticated-orcid":false,"given":"Alice J.","family":"Coates","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5529-7815","authenticated-orcid":false,"given":"Samuel J.","family":"Tingle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9061-8766","authenticated-orcid":false,"given":"Dharesh Raj","family":"Amarnath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1051-078X","authenticated-orcid":false,"given":"Georgios","family":"Kourounis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4822-7223","authenticated-orcid":false,"given":"Andrew J.","family":"Fisher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4727-6085","authenticated-orcid":false,"given":"John H.","family":"Dark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.healun.2026.09.006_bib1","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1016\/j.transproceed.2025.10.001","article-title":"Waiting list mortality and potential risk factors in lung transplant candidates: a single-center data","volume":"57","author":"Saribas","year":"2025","journal-title":"Transplant Proc"},{"key":"10.1016\/j.healun.2026.09.006_bib2","unstructured":"NHS Blood and Transplant. NHSBT Annual Report on Cardiothoracic Organ Transplantation Report for 2024\/2025 [Internet]. 2025 [cited 2026 May 28]. Available from: https:\/\/nhsbtdbe.blob.core.windows.net\/umbraco-assets-corp\/37115\/nhsbt-lung-transplantation-report-2425.pdf."},{"issue":"2_Suppl 1","key":"10.1016\/j.healun.2026.09.006_bib3","doi-asserted-by":"crossref","first-page":"S422","DOI":"10.1016\/j.ajt.2025.01.025","article-title":"OPTN\/SRTR 2023 annual data report: lung","volume":"25","author":"Valapour","year":"2025","journal-title":"Am J Transplant"},{"issue":"9_Suppl","key":"10.1016\/j.healun.2026.09.006_bib4","doi-asserted-by":"crossref","first-page":"S217","DOI":"10.1016\/j.healun.2004.06.017","article-title":"Physiologic changes during brain stem death--lessons for management of the organ donor","volume":"23","author":"Smith","year":"2004","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2026.09.006_bib5","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1034\/j.1600-6143.2002.20316.x","article-title":"Duration of donor brain death and its influence on kidney graft function","volume":"2","author":"Kunzendorf","year":"2002","journal-title":"Am J Transplant"},{"key":"10.1016\/j.healun.2026.09.006_bib6","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1016\/j.jtcvs.2019.04.060","article-title":"Influence of donor brain death duration on outcomes following heart transplantation: a United Network for Organ Sharing Registry analysis","volume":"159","author":"Jawitz","year":"2020","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.healun.2026.09.006_bib7","doi-asserted-by":"crossref","first-page":"147","DOI":"10.12659\/AOT.913869","article-title":"Prolonged duration of brain death was associated with better kidney allograft function and survival: a prospective cohort analysis","volume":"24","author":"Ergun","year":"2019","journal-title":"Ann Transplant"},{"key":"10.1016\/j.healun.2026.09.006_bib8","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1093\/ejcts\/ezx513","article-title":"The interval between brainstem death and cardiac assessment influences the retrieval of hearts for transplantation","volume":"53","author":"Dimarakis","year":"2018","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.healun.2026.09.006_bib9","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.1600-6143.2006.01593.x","article-title":"Early hemodynamic injury during donor brain death determines the severity of primary graft dysfunction after lung transplantation","volume":"7","author":"Avlonitis","year":"2007","journal-title":"Am J Transplant"},{"key":"10.1016\/j.healun.2026.09.006_bib10","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1093\/ejcts\/ezw028","article-title":"Impact of time interval between donor brain death and cold preservation on long-term outcome in lung transplantation","volume":"50","author":"Pecoraro","year":"2016","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.healun.2026.09.006_bib11","doi-asserted-by":"crossref","first-page":"e68","DOI":"10.1016\/j.ejcts.2010.11.049","article-title":"Donor cause of brain death and related time intervals: does it affect outcome after lung transplantation?","volume":"39","author":"Wauters","year":"2011","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.healun.2026.09.006_bib12","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1016\/j.athoracsur.2019.05.026","article-title":"Impact of donor brain death duration on outcomes after lung transplantation","volume":"108","author":"Jawitz","year":"2019","journal-title":"Ann Thorac Surg"},{"issue":"4 Pt 1","key":"10.1016\/j.healun.2026.09.006_bib13","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1111\/j.1600-6143.2005.00755.x","article-title":"The hemodynamic mechanisms of lung injury and systemic inflammatory response following brain death in the transplant donor","volume":"5","author":"Avlonitis","year":"2005","journal-title":"Am J Transplant"},{"key":"10.1016\/j.healun.2026.09.006_bib14","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1056\/NEJM200005043421801","article-title":"Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome","volume":"342","author":"Acute Respiratory Distress Syndrome Network","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.healun.2026.09.006_bib15","doi-asserted-by":"crossref","first-page":"10448","DOI":"10.3390\/ijms262110448","article-title":"Ventilator-associated lung injury: pathophysiology, prevention, and emerging therapeutic strategies","volume":"26","author":"Costa","year":"2025","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.healun.2026.09.006_bib16","doi-asserted-by":"crossref","first-page":"2620","DOI":"10.1001\/jama.2010.1796","article-title":"Effect of a lung protective strategy for organ donors on eligibility and availability of lungs for transplantation: a randomized controlled trial","volume":"304","author":"Mascia","year":"2010","journal-title":"JAMA"},{"key":"10.1016\/j.healun.2026.09.006_bib17","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1164\/rccm.201910-2067OC","article-title":"Effect of lung-protective ventilation in organ donors on lung procurement and recipient survival","volume":"202","author":"Mal","year":"2020","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.healun.2026.09.006_bib18","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.healun.2014.09.024","article-title":"Lung donor treatment protocol in brain dead-donors: a multicenter study","volume":"34","author":"Minambres","year":"2015","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2026.09.006_bib19","unstructured":"Organ Procurement and Transplantation Network. Request Data [Internet]. [cited 2026 May 28]. Available from: https:\/\/optn.transplant.hrsa.gov\/data\/view-data-reports\/request-data\/."},{"key":"10.1016\/j.healun.2026.09.006_bib20","unstructured":"Health Research Authority. Do I need NHS REC review? HRA Decision Tools [Internet]. [cited 2026 May 28]. Available from: https:\/\/www.hra-decisiontools.org.uk\/ethics\/."},{"key":"10.1016\/j.healun.2026.09.006_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhlto.2024.100107","article-title":"Body mass index and mortality following primary graft dysfunction: a lung transplant outcomes group study","volume":"5","author":"Bennett","year":"2024","journal-title":"JHLT Open"},{"key":"10.1016\/j.healun.2026.09.006_bib22","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/j.healun.2017.07.021","article-title":"Report of the ISHLT Working Group on Primary Lung Graft Dysfunction, part I: Definition and grading-a 2016 Consensus Group statement of the International Society for Heart and Lung Transplantation","volume":"36","author":"Snell","year":"2017","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2026.09.006_bib23","series-title":"Hmisc: Harrell Miscellaneous. Version 5.2-2 2026","author":"Harrell","year":"2026"},{"key":"10.1016\/j.healun.2026.09.006_bib24","series-title":"Multiple Imputation for Nonresponse in Surveys","author":"Rubin","year":"1987"},{"key":"10.1016\/j.healun.2026.09.006_bib25","series-title":"rms: Regression Modeling Strategies. Version 7.0-0","author":"Harrell","year":"2025"},{"key":"10.1016\/j.healun.2026.09.006_bib26","series-title":"R: A language and environment for statistical computing","author":"R Core Team","year":"2025"},{"key":"10.1016\/j.healun.2026.09.006_bib27","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.21105\/joss.01686","article-title":"Welcome to the tidyverse","volume":"4","author":"Wickham","year":"2019","journal-title":"J Open Source Softw"},{"key":"10.1016\/j.healun.2026.09.006_bib28","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1093\/postmj\/qgaf183","article-title":"Non-linear regression modelling for medical professionals; making curved paths straightforward","volume":"102","author":"Tingle","year":"2026","journal-title":"Postgrad Med J"},{"key":"10.1016\/j.healun.2026.09.006_bib29","series-title":"survival: survival analysis. Version 3.8-6","author":"Therneau","year":"2026"},{"key":"10.1016\/j.healun.2026.09.006_bib30","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.healun.2020.10.009","article-title":"Risk factors for mortality in lung transplant recipients aged \u2265 65 years: a retrospective cohort study of 5,815 patients in the scientific registry of transplant recipients","volume":"40","author":"Mosher","year":"2021","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2026.09.006_bib31","first-page":"160","article-title":"Pulmonary allograft ischemic time: an important predictor of survival after lung transplantation","volume":"15","author":"Snell","year":"1996","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2026.09.006_bib32","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1186\/s12890-024-03317-x","article-title":"Donor age over 55 is associated with worse outcome in lung transplant recipients with idiopathic pulmonary fibrosis","volume":"24","author":"Moneke","year":"2024","journal-title":"BMC Pulm Med"},{"key":"10.1016\/j.healun.2026.09.006_bib33","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1164\/rccm.201210-1865OC","article-title":"Clinical risk factors for primary graft dysfunction after lung transplantation","volume":"187","author":"Diamond","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.healun.2026.09.006_bib34","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/j.healun.2010.05.013","article-title":"Construct validity of the definition of primary graft dysfunction after lung transplantation","volume":"29","author":"Christie","year":"2010","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.healun.2026.09.006_bib35","doi-asserted-by":"crossref","first-page":"203","DOI":"10.21926\/obm.transplant.2304203","article-title":"Lung donor selection and management: an updated review","volume":"7","author":"Mody","year":"2023","journal-title":"OBM Transplant"},{"key":"10.1016\/j.healun.2026.09.006_bib36","series-title":"Modern Epidemiology","author":"Rothman","year":"2008"},{"key":"10.1016\/j.healun.2026.09.006_bib37","doi-asserted-by":"crossref","first-page":"e1071","DOI":"10.1097\/TP.0000000000005647","article-title":"Longer duration of donor ventilation is not associated with long-term lung function after lung transplantation","volume":"110","author":"Fioretti","year":"2026","journal-title":"Transplantation"},{"key":"10.1016\/j.healun.2026.09.006_bib38","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1097\/TP.0b013e31822bf790","article-title":"Survival determinants in lung transplant patients with chronic allograft dysfunction","volume":"92","author":"Verleden","year":"2011","journal-title":"Transplantation"},{"key":"10.1016\/j.healun.2026.09.006_bib39","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.healun.2019.03.009","article-title":"Chronic lung allograft dysfunction: Definition, diagnostic criteria, and approaches to treatment-a consensus report from the Pulmonary Council of the ISHLT","volume":"38","author":"Verleden","year":"2019","journal-title":"J Heart Lung Transplant"}],"container-title":["The Journal of Heart and Lung Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053249826020887?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053249826020887?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T20:16:20Z","timestamp":1792008980000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1053249826020887"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":39,"alternative-id":["S1053249826020887"],"URL":"https:\/\/doi.org\/10.1016\/j.healun.2026.09.006","relation":{},"ISSN":["1053-2498"],"issn-type":[{"value":"1053-2498","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Investigating the impact of donor brain death duration on outcomes after lung transplant","name":"articletitle","label":"Article Title"},{"value":"The Journal of Heart and Lung Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.healun.2026.09.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of International Society for Heart and Lung Transplantation.","name":"copyright","label":"Copyright"}]}}