{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T20:21:08Z","timestamp":1767990068441,"version":"3.49.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hearing Research"],"published-print":{"date-parts":[[2006,4]]},"DOI":"10.1016\/j.heares.2005.12.008","type":"journal-article","created":{"date-parts":[[2006,3,4]],"date-time":"2006-03-04T07:24:18Z","timestamp":1141457058000},"page":"1-6","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["The effects of tempol, 3-aminobenzamide and nitric oxide synthase inhibitors on acoustic injury of the mouse cochlea"],"prefix":"10.1016","volume":"214","author":[{"given":"Hidekazu","family":"Murashita","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiji","family":"Tabuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomofumi","family":"Hoshino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeki","family":"Tsuji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Hara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.heares.2005.12.008_bib1","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1046\/j.1471-4159.1998.70020501.x","article-title":"Peroxynitrite and hydrogen peroxide induced cell death in the NSC34 neuroblastoma\u00d7spinal cord cell line: role of poly (ADP-ribose) polymerase","volume":"70","author":"Cookson","year":"1998","journal-title":"J. Neurochem."},{"key":"10.1016\/j.heares.2005.12.008_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-5955(96)00053-6","article-title":"Effect of sodium nitroprusside on compound action potential thresholds in the gerbil cochlea","volume":"99","author":"Dais","year":"1996","journal-title":"Hearing Res."},{"key":"10.1016\/j.heares.2005.12.008_bib3","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1146\/annurev.bi.64.070195.000525","article-title":"Superoxide radical and superoxide dismutases","volume":"64","author":"Fridovich","year":"1995","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.heares.2005.12.008_bib4","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S0378-5955(00)00029-0","article-title":"Hydroxyl radical formation in the perilymph of asphyxic guinea pig","volume":"143","author":"Hara","year":"2000","journal-title":"Hearing Res."},{"key":"10.1016\/j.heares.2005.12.008_bib5","doi-asserted-by":"crossref","first-page":"11176","DOI":"10.1074\/jbc.270.19.11176","article-title":"Inactivation of the poly (ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells","volume":"270","author":"Heller","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.heares.2005.12.008_bib6","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1016\/S0021-9258(19)77928-9","article-title":"Mechanisms of oxidant-mediated cell injury","volume":"263","author":"Hyslop","year":"1988","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.heares.2005.12.008_bib7","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S1382-6689(96)00143-3","article-title":"Microassay of superoxide anion scavenging activity in vitro","volume":"3","author":"Laight","year":"1997","journal-title":"Environ. Toxicol. Pharm."},{"key":"10.1016\/j.heares.2005.12.008_bib8","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/0891-5849(96)00124-4","article-title":"Protective effect of the nitroxide tempol against the cardiotoxicity of adriamycin","volume":"21","author":"Monti","year":"1996","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.heares.2005.12.008_bib9","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0005-2728(99)00029-8","article-title":"Nitric oxide and cell death","volume":"1411","author":"Murphy","year":"1999","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1016\/j.heares.2005.12.008_bib10","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1159\/000013846","article-title":"Early elevation of cochlear reactive oxygen species following noise exposure","volume":"4","author":"Ohlemiller","year":"1999","journal-title":"Audiol. Neurootol."},{"key":"10.1016\/j.heares.2005.12.008_bib11","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1159\/000013847","article-title":"Targeted deletion of the cytosolic Cu\/Zn-superoxide dismutase gene (Sod1) increases susceptibility to noise-induced hearing loss","volume":"4","author":"Ohlemiller","year":"1999","journal-title":"Audiol. Neurootol."},{"key":"10.1016\/j.heares.2005.12.008_bib12","first-page":"385","article-title":"Tempol and deferoxamine protect cultured rabbit lens epithelial cells from H2O2 insult: insight into the mechanism of H2O2-induced injury","volume":"9","author":"Reddan","year":"1992","journal-title":"Lens Eye Toxic. Res."},{"key":"10.1016\/j.heares.2005.12.008_bib13","doi-asserted-by":"crossref","first-page":"17921","DOI":"10.1016\/S0021-9258(19)81304-2","article-title":"A novel metal-free low molecular weight superoxide dismutase mimic","volume":"263","author":"Samuni","year":"1988","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.heares.2005.12.008_bib14","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1172\/JCI115163","article-title":"Nitroxide stable radicals protect beating cardiomyocytes against oxidative damage","volume":"87","author":"Samuni","year":"1991","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.heares.2005.12.008_bib15","doi-asserted-by":"crossref","first-page":"4908","DOI":"10.1073\/pnas.83.13.4908","article-title":"Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly (ADP-ribose) polymerase","volume":"83","author":"Schraufstatter","year":"1986","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.heares.2005.12.008_bib16","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1177\/019459989310900613","article-title":"The protective effects of allopurinol and superoxide dismutase on noise-induced cochlear damage","volume":"109","author":"Seidman","year":"1993","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"10.1016\/j.heares.2005.12.008_bib17","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0378-5955(01)00409-9","article-title":"The electrochemical and fluorescence detection of nitric oxide in the cochlea and its increase following loud sound","volume":"164","author":"Shi","year":"2002","journal-title":"Hearing Res."},{"key":"10.1016\/j.heares.2005.12.008_bib18","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1172\/JCI119585","article-title":"Endothelial dysfunction in a rat model of endotoxic shock: importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite","volume":"100","author":"Szabo","year":"1997","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.heares.2005.12.008_bib19","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1080\/00016489950181620","article-title":"Effect of nitric oxide synthase inhibitor on cochlear dysfunction induced by transient local anoxia","volume":"119","author":"Tabuchi","year":"1999","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.heares.2005.12.008_bib20","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1177\/000348940010900803","article-title":"Effect of 7-nitroindazole upon cochlear dysfunction induced by transient local anoxia","volume":"109","author":"Tabuchi","year":"2000","journal-title":"Ann. Otol. Rhinol. Laryngol."},{"key":"10.1016\/j.heares.2005.12.008_bib21","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1620\/tjem.200.195","article-title":"Involvement of poly (ADP-ribose) synthetase in acoustic trauma of the cochlea","volume":"200","author":"Tabuchi","year":"2003","journal-title":"Tohoku J. Exp. Med."},{"key":"10.1016\/j.heares.2005.12.008_bib22","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.ejphar.2004.01.019","article-title":"The clinical free radical scavenger, edaravone, protects cochlear hair cells from acoustic trauma","volume":"487","author":"Takemoto","year":"2004","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.heares.2005.12.008_bib23","first-page":"246","article-title":"Possible involvement of free radicals in lipopolysaccharide-induced labyrinthitis in the guinea pig: a morphological and functional investigation","volume":"60","author":"Takumida","year":"1998","journal-title":"J. Otolaryngol. Relat. Spectorsc."},{"key":"10.1016\/j.heares.2005.12.008_bib24","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/S0378-5955(02)00299-X","article-title":"Long-term observation on the reversibility of cochlear dysfunction after transient ischemia","volume":"166","author":"Tsuji","year":"2002","journal-title":"Hearing Res."},{"key":"10.1016\/j.heares.2005.12.008_bib25","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0006-8993(98)01100-7","article-title":"Attenuation of cochlear damage from noise trauma by an iron chelator, a free radical scavenger and glial cell line-derived neurotrophic factor in vivo","volume":"815","author":"Yamasoba","year":"1999","journal-title":"Brain Res."}],"container-title":["Hearing Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595505003667?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595505003667?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T10:45:08Z","timestamp":1759920308000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378595505003667"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4]]},"references-count":25,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["S0378595505003667"],"URL":"https:\/\/doi.org\/10.1016\/j.heares.2005.12.008","relation":{},"ISSN":["0378-5955"],"issn-type":[{"value":"0378-5955","type":"print"}],"subject":[],"published":{"date-parts":[[2006,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effects of tempol, 3-aminobenzamide and nitric oxide synthase inhibitors on acoustic injury of the mouse cochlea","name":"articletitle","label":"Article Title"},{"value":"Hearing Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.heares.2005.12.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}