{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T04:05:18Z","timestamp":1773288318762,"version":"3.50.1"},"reference-count":43,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hearing Research"],"published-print":{"date-parts":[[2006,5]]},"DOI":"10.1016\/j.heares.2006.03.014","type":"journal-article","created":{"date-parts":[[2006,5,9]],"date-time":"2006-05-09T07:13:20Z","timestamp":1147158800000},"page":"97-107","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Structure and locomotion of adult in vitro regenerated spiral ganglion growth cones \u2013 A study using video microscopy and SEM"],"prefix":"10.1016","volume":"215","author":[{"given":"Malin","family":"Anderson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marja","family":"Bostr\u00f6m","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristian","family":"Pfaller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rudolf","family":"Glueckert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annelies","family":"Schrott-Fischer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bengt","family":"Gerdin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helge","family":"Rask-Andersen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.heares.2006.03.014_bib1","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/s001060050597","article-title":"Effect of fibroblast growth factor-1 (FGF-1) on spiral ganglion cells of the mammalian cochlea","volume":"48","author":"Aletsee","year":"2000","journal-title":"HNO"},{"key":"10.1016\/j.heares.2006.03.014_bib2","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s10162001000086","article-title":"Ras\/MEK but not p38 signaling mediates NT-3-induced neurite extension from spiral ganglion neurons","volume":"2","author":"Aletsee","year":"2001","journal-title":"J. Assoc. Res. Otolaryngol."},{"key":"10.1016\/j.heares.2006.03.014_bib3","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1523\/JNEUROSCI.08-04-01425.1988","article-title":"Growth cone configuration and advance: a time-lapse study using video-enhanced differential interference contrast microscopy","volume":"8","author":"Aletta","year":"1988","journal-title":"J. Neurosci."},{"key":"10.1016\/j.heares.2006.03.014_bib4","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1073\/pnas.65.4.905","article-title":"Surface movements during the growth of single explanted neurons","volume":"65","author":"Bray","year":"1970","journal-title":"PNAS"},{"key":"10.1016\/j.heares.2006.03.014_bib5","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1242\/jcs.37.1.391","article-title":"Mechanical tension produced by nerve cells in culture","volume":"37","author":"Bray","year":"1979","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.heares.2006.03.014_bib6","doi-asserted-by":"crossref","first-page":"3204","DOI":"10.1523\/JNEUROSCI.05-12-03204.1985","article-title":"Analysis of microspike movements on the neuronal growth cone","volume":"5","author":"Bray","year":"1985","journal-title":"J. Neurosci."},{"key":"10.1016\/j.heares.2006.03.014_bib7","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1006\/exnr.1999.7123","article-title":"Regeneration and proliferation of embryonic and adult rat hippocampal neurons in culture","volume":"159","author":"Brewer","year":"1999","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.heares.2006.03.014_bib8","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1083\/jcb.108.1.95","article-title":"The organization of myosin and actin in rapid frozen nerve growth cones","volume":"108","author":"Bridgman","year":"1989","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.heares.2006.03.014_bib9","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1083\/jcb.56.3.713","article-title":"Fine structure of nerve fibers and growth cones of isolated sympathetic neurons in culture","volume":"56","author":"Bunge","year":"1973","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.heares.2006.03.014_bib10","first-page":"609","article-title":"A quelle \u00e9poque apparaissent les expansion des cellules nerveuses de la moelle epiniere du poulet?","volume":"21\u201322","author":"Cajal","year":"1890","journal-title":"Anatomischer Anzeiger"},{"key":"10.1016\/j.heares.2006.03.014_bib11","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0896-6273(03)00633-0","article-title":"Cytoskeletal dynamics and transport in growth cone motility and axon guidance","volume":"40","author":"Dent","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.heares.2006.03.014_bib12","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1038\/386796a0","article-title":"Phenotype of mice lacking functional deleted in colorectal cancer (Dcc) gene","volume":"386","author":"Fazeli","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.heares.2006.03.014_bib13","doi-asserted-by":"crossref","first-page":"6170","DOI":"10.1523\/JNEUROSCI.21-16-06170.2001","article-title":"Spatial shaping of cochlear innervation by temporally regulated neurotrophin expression","volume":"21","author":"Farinas","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.heares.2006.03.014_bib14","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.heares.2004.07.004","article-title":"Netrin-1 as a guidance molecules in the postnatal rat cochlea","volume":"199","author":"Gillespie","year":"2005","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2006.03.014_bib15","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/ar.1090010503","article-title":"Observations on the living developing nerve fiber","volume":"1","author":"Harrison","year":"1907","journal-title":"Anat. Rec."},{"key":"10.1016\/j.heares.2006.03.014_bib16","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/S0959-4388(97)80080-3","article-title":"The growing family of myosin motors and their role in neurons and sensory cells","volume":"7","author":"Hasson","year":"1997","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.heares.2006.03.014_bib17","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0896-6273(90)90444-K","article-title":"The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans","volume":"4","author":"Hedgecock","year":"1990","journal-title":"Neuron"},{"key":"10.1016\/j.heares.2006.03.014_bib18","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1523\/JNEUROSCI.17-06-01959.1997","article-title":"Trophic support of cultured spiral ganglion neurons by depolarization exceeds and is additive with that by neurotrophins or cAMP and requires elevation of [Ca2+]i within a set range","volume":"17","author":"Hegarty","year":"1997","journal-title":"J. Neurosci."},{"key":"10.1016\/j.heares.2006.03.014_bib19","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0165-3806(01)00221-8","article-title":"Developmental expression of DCC in the rat retina","volume":"130","author":"Johansson","year":"2001","journal-title":"Brain Res. Dev. Brain Res."},{"key":"10.1016\/j.heares.2006.03.014_bib20","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1097\/00001756-199807130-00007","article-title":"GDNF protects the cochlea against noise damage","volume":"9","author":"Keithley","year":"1998","journal-title":"Neuroreport"},{"key":"10.1016\/j.heares.2006.03.014_bib21","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1126\/science.3576221","article-title":"Antisense RNA inactivation of myosin heavy chain gene expression in Dictyostelium discoideum","volume":"236","author":"Knecht","year":"1987","journal-title":"Science"},{"key":"10.1016\/j.heares.2006.03.014_bib22","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/340159a0","article-title":"Direct evidence that growth cones pull","volume":"340","author":"Lamoureux","year":"1989","journal-title":"Nature"},{"key":"10.1016\/j.heares.2006.03.014_bib23","doi-asserted-by":"crossref","first-page":"304","DOI":"10.3109\/00016489109137392","article-title":"Temporal pattern of nerve growth factor (NGF) binding in vivo and in vitro effects of NGF on cultures of developing auditory and vestibular neurons","volume":"111","author":"Lefebvre","year":"1991","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.heares.2006.03.014_bib24","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1080\/00016489.1992.11665420","article-title":"Nerve growth factor stimulates neurite regeneration but not survival of adult auditory neurons in vitro","volume":"112","author":"Lefebvre","year":"1992","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.heares.2006.03.014_bib25","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1002\/cm.970080302","article-title":"\u201cPull\u201d and \u201cpush\u201d in neurite elongation: observations on the effects of different concentrations of cytochalasin B and taxol","volume":"8","author":"Letourneau","year":"1987","journal-title":"Cell Motil. Cytoskeleton"},{"key":"10.1016\/j.heares.2006.03.014_bib26","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/S0896-6273(00)80097-5","article-title":"Myosin drives retrograde F-actin flow in neuronal growth cones","volume":"16","author":"Lin","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/j.heares.2006.03.014_bib27","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1083\/jcb.99.6.2041","article-title":"Growth of neurites without filopodial or lamellipodial activity in the presence of cytochalasin B","volume":"99","author":"Marsh","year":"1984","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.heares.2006.03.014_bib28","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0896-6273(01)00217-3","article-title":"Electrical activity modulates growth cone guidance by diffusible factors","volume":"29","author":"Ming","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.heares.2006.03.014_bib29","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/0896-6273(88)90124-9","article-title":"Cytoskeletal dynamics and nerve growth","volume":"1","author":"Mitchison","year":"1988","journal-title":"Neuron"},{"key":"10.1016\/j.heares.2006.03.014_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0006-8993(01)02038-8","article-title":"Neuronal properties in cultured ultimobranchial C cells of chick embryos: process outgrowth and expression of TuJ1 and enkephalin","volume":"905","author":"Miura","year":"2001","journal-title":"Brain Res."},{"key":"10.1016\/j.heares.2006.03.014_bib31","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1097\/01.mao.0000187239.56583.d2","article-title":"Innervation of the apical turn of the human cochlea: A light microscopic and transmission electron microscopic investigation","volume":"27","author":"Pamulova","year":"2006","journal-title":"Otol. Neurotol."},{"key":"10.1016\/j.heares.2006.03.014_bib32","doi-asserted-by":"crossref","first-page":"9915","DOI":"10.1073\/pnas.89.20.9915","article-title":"Brain-derived neurotrophic factor and neurotrophin 3 mRNAs in the peripheral target fields of developing inner ear ganglia","volume":"89","author":"Pirvola","year":"1992","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.heares.2006.03.014_bib33","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.heares.2004.12.005","article-title":"Regeneration of human auditory nerve. In vitro\/in video demonstration of neural progenitor cells in adult human and guinea pig spiral ganglion","volume":"203","author":"Rask-Andersen","year":"2005","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2006.03.014_bib34","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1126\/science.1553558","article-title":"Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system","volume":"255","author":"Reynolds","year":"1992","journal-title":"Science"},{"key":"10.1016\/j.heares.2006.03.014_bib35","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1091\/mbc.10.7.2309","article-title":"Polymerizing microtubules activate site-directed f-actin assembly in nerve growth cones","volume":"10","author":"Rochlin","year":"1999","journal-title":"Mol. Biol. Cell."},{"key":"10.1016\/j.heares.2006.03.014_bib36","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0925-4773(01)00350-1","article-title":"Localization of the netrin guidance receptor, DCC, in the developing peripheral and enteric nervous systems","volume":"103","author":"Seaman","year":"2001","journal-title":"Mech. Dev."},{"key":"10.1016\/j.heares.2006.03.014_bib37","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0892-0354(98)90010-7","article-title":"The actin cytoskeleton","volume":"1","author":"Small","year":"1988","journal-title":"Electron Microsc. Rev."},{"key":"10.1016\/j.heares.2006.03.014_bib38","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/S0959-4388(98)80014-7","article-title":"An emerging link between cytoskeletal dynamics and cell adhesion molecules in growth cone guidance","volume":"8","author":"Suter","year":"1998","journal-title":"Curr. Opin. in Neurobiol."},{"key":"10.1016\/j.heares.2006.03.014_bib39","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1083\/jcb.200210174","article-title":"Mechanism of filopodia initiation by reorganization of a dendritic network","volume":"160","author":"Svitkina","year":"2003","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.heares.2006.03.014_bib40","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1126\/science.274.5290.1123","article-title":"The molecular biology of axon guidance","volume":"274","author":"Tessier-Lavigne","year":"1996","journal-title":"Science"},{"key":"10.1016\/j.heares.2006.03.014_bib41","doi-asserted-by":"crossref","first-page":"227","DOI":"10.3109\/00016488909125522","article-title":"Determinants of ganglion-receptor cell interaction during development of the inner ear. A heterochronic ganglia study","volume":"108","author":"Van de Water","year":"1989","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.heares.2006.03.014_bib42","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1074\/jbc.272.1.249","article-title":"Glial cell line-derived neurotrophic factor induces Ret-mediated lamellipodia formation","volume":"272","author":"Weering van","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.heares.2006.03.014_bib43","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.neuroscience.2005.11.030","article-title":"Survival and morphology of auditory neurons in dissociated cultures of newborn mouse spiral ganglion","volume":"138","author":"Whitlon","year":"2006","journal-title":"Neuroscience"}],"container-title":["Hearing Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595506000839?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595506000839?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T10:45:41Z","timestamp":1759920341000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378595506000839"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,5]]},"references-count":43,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2006,5]]}},"alternative-id":["S0378595506000839"],"URL":"https:\/\/doi.org\/10.1016\/j.heares.2006.03.014","relation":{},"ISSN":["0378-5955"],"issn-type":[{"value":"0378-5955","type":"print"}],"subject":[],"published":{"date-parts":[[2006,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Structure and locomotion of adult in vitro regenerated spiral ganglion growth cones \u2013 A study using video microscopy and SEM","name":"articletitle","label":"Article Title"},{"value":"Hearing Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.heares.2006.03.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}