{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T13:06:17Z","timestamp":1791896777693,"version":"4.3.4"},"reference-count":60,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2007,10,1]],"date-time":"2007-10-01T00:00:00Z","timestamp":1191196800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hearing Research"],"published-print":{"date-parts":[[2007,10]]},"DOI":"10.1016\/j.heares.2007.07.001","type":"journal-article","created":{"date-parts":[[2007,7,13]],"date-time":"2007-07-13T07:45:21Z","timestamp":1184312721000},"page":"87-103","source":"Crossref","is-referenced-by-count":24,"title":["Acoustic\u2013electric interactions in the guinea pig auditory nerve: Simultaneous and forward masking of the electrically evoked compound action potential"],"prefix":"10.1016","volume":"232","author":[{"given":"Kirill V.","family":"Nourski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.","family":"Abbas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles A.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara K.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuh-Cherng","family":"Jeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.heares.2007.07.001_bib1","unstructured":"Abbas, P.J., Miller, C.A., Rubinstein, J.T., Robinson, B.K., 2001. Effects of remaining hair cells on cochlear implant function. Seventh Quarterly Progress Report. Neural Prosthesis Program contract N01-DC-9-2106 NIH."},{"key":"10.1016\/j.heares.2007.07.001_bib2","unstructured":"Abbas, P.J., Miller, C.A., Robinson, B.K., Jeng, F.C., Nourski, K.V., 2003. Effects of remaining hair cells on cochlear implant function. Fourth Quarterly Progress Report, Neural Prosthesis Program contract N01-DC-2-1005 NIH."},{"key":"10.1016\/j.heares.2007.07.001_bib3","unstructured":"Abbas, P.J., Miller, C.A., Robinson, B.K., Jeng, F.C., Noh, H., Nourski, K.V., 2004. Effects of remaining hair cells on cochlear implant function. Sixth Quarterly Progress Report, Neural Prosthesis Program contract N01-DC-2-1005 NIH."},{"key":"10.1016\/j.heares.2007.07.001_bib4","unstructured":"Abbas, P.J., Etler, C., Nourski, K., Brown, C., Miller, C., 2005. Responses to electrical stimulation in individuals with residual hair cell function. Fourth International Symposium and Workshops: Objective Measures in Cochlear Implants, June 1\u20134, 2005, Hannover, Germany."},{"issue":"3\u20134","key":"10.1016\/j.heares.2007.07.001_bib5","doi-asserted-by":"crossref","first-page":"201","DOI":"10.3109\/00016487809124737","article-title":"A physiological and morphological study of the cochlea of the rat following treatment with atoxyl and neomycin","volume":"86","author":"Anniko","year":"1978","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.heares.2007.07.001_bib6","first-page":"320","article-title":"Preliminary experience with neural response telemetry in the nucleus CI24M cochlear implant","volume":"19","author":"Brown","year":"1998","journal-title":"Am. J. Otol."},{"issue":"2","key":"10.1016\/j.heares.2007.07.001_bib7","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1097\/00003446-200004000-00009","article-title":"The relationship between EAP and EABR thresholds and levels used to program the nucleus 24 speech processor: data from adults","volume":"21","author":"Brown","year":"2000","journal-title":"Ear Hear."},{"key":"10.1016\/j.heares.2007.07.001_bib8","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1159\/000078389","article-title":"Cochlear implant candidacy and surgical considerations","volume":"9","author":"Cohen","year":"2004","journal-title":"Audiol. Neurootol."},{"key":"10.1016\/j.heares.2007.07.001_bib9","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1146\/annurev.med.55.091902.105251","article-title":"Cochlear implantation for the treatment of deafness","volume":"55","author":"Copeland","year":"2004","journal-title":"Annu. Rev. Med."},{"issue":"4","key":"10.1016\/j.heares.2007.07.001_bib10","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1097\/00003446-200508000-00001","article-title":"Acoustic simulations of combined electric and acoustic hearing (EAS)","volume":"26","author":"Dorman","year":"2005","journal-title":"Ear Hear."},{"issue":"6","key":"10.1016\/j.heares.2007.07.001_bib11","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1097\/00003446-200412000-00002","article-title":"Electrically evoked compound action potential amplitude growth functions and HiResolution programming levels in pediatric CII implant subjects","volume":"25","author":"Eisen","year":"2004","journal-title":"Ear Hear."},{"issue":"4","key":"10.1016\/j.heares.2007.07.001_bib12","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1080\/00016480410016423","article-title":"Combining acoustic and electrical speech processing: Iowa\/Nucleus hybrid implant","volume":"124","author":"Gantz","year":"2004","journal-title":"Acta Otolaryngol."},{"issue":"Suppl. 1","key":"10.1016\/j.heares.2007.07.001_bib13","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1159\/000095616","article-title":"Acoustic plus electric speech processing: preliminary results of a multicenter clinical trial of the Iowa\/Nucleus hybrid implant","volume":"11","author":"Gantz","year":"2006","journal-title":"Audiol. Neurootol."},{"issue":"Suppl. 1","key":"10.1016\/j.heares.2007.07.001_bib14","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1159\/000095614","article-title":"Ipsilateral electric acoustic stimulation of the auditory system: results of long-term hearing preservation","volume":"11","author":"Gstoettner","year":"2006","journal-title":"Audiol. Neurootol."},{"key":"10.1016\/j.heares.2007.07.001_bib15","doi-asserted-by":"crossref","first-page":"353","DOI":"10.3109\/00206099809072989","article-title":"Electrically evoked compound action potential (ECAP) of the cochlear nerve in response to pulsatile electrical stimulation of the cochlea in the rat: effects of stimulation at high rates","volume":"37","author":"Haenggeli","year":"1998","journal-title":"Audiology"},{"issue":"4","key":"10.1016\/j.heares.2007.07.001_bib16","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1152\/jn.1979.42.4.1083","article-title":"Forward masking of auditory nerve fiber responses","volume":"42","author":"Harris","year":"1979","journal-title":"J. Neurophysiol."},{"issue":"6","key":"10.1016\/j.heares.2007.07.001_bib17","first-page":"731","article-title":"Temporal bone histopathology of cisplatin ototoxicity","volume":"16","author":"Hinojosa","year":"1995","journal-title":"Am. J. Otol."},{"issue":"10","key":"10.1016\/j.heares.2007.07.001_bib18","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1097\/00005537-200110000-00025","article-title":"Aminoglycoside ototoxicity: a human temporal bone study","volume":"111","author":"Hinojosa","year":"2001","journal-title":"Laryngoscope"},{"key":"10.1016\/j.heares.2007.07.001_bib19","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/0378-5955(84)90052-2","article-title":"Physiological properties of the electrically stimulated auditory nerve. II. Single fiber recordings","volume":"14","author":"van den Honert","year":"1984","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2007.07.001_bib20","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0378-5955(03)00261-2","article-title":"Auditory response to intracochlear electric stimuli following furosemide treatment","volume":"185","author":"Hu","year":"2003","journal-title":"Hear. Res."},{"issue":"6","key":"10.1016\/j.heares.2007.07.001_bib21","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1159\/000027695","article-title":"Electric\u2013acoustic stimulation of the auditory system. New technology for severe hearing loss","volume":"61","author":"von Ilberg","year":"1999","journal-title":"ORL J. Otorhinolaryngol. Relat. Spec."},{"issue":"5","key":"10.1016\/j.heares.2007.07.001_bib22","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1080\/00016480510026197","article-title":"Preservation of residual hearing with cochlear implantation: how and why","volume":"125","author":"James","year":"2005","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.heares.2007.07.001_bib23","unstructured":"Kiang, N.Y.-S., Wanatabe, T., Thomas, E.C., Clark, L.F., 1965. Discharge patterns of single fibers in the cat\u2019s auditory nerve. Research Monograph No. 35. MIT Press, Cambridge, MA."},{"key":"10.1016\/j.heares.2007.07.001_bib24","series-title":"Cochlear Implants: An Update","first-page":"569","article-title":"Fundamental aspects and first results of the clinical application of combined electric and acoustic stimulation of the auditory system","author":"Kiefer","year":"2002"},{"key":"10.1016\/j.heares.2007.07.001_bib25","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1159\/000084023","article-title":"Combined electric and acoustic stimulation of the auditory system: results of a clinical study","volume":"10","author":"Kiefer","year":"2005","journal-title":"Audiol. Neurootol."},{"key":"10.1016\/j.heares.2007.07.001_bib26","unstructured":"Killian, M.J.P., 1994. Excitability of the electrically stimulated auditory nerve. Ph.D. dissertation. University of Utrecht, Utrecht, The Netherlands."},{"key":"10.1016\/j.heares.2007.07.001_bib27","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/0378-5955(94)90154-6","article-title":"Adaptation in the compound action potential response of the guinea pig VIIIth nerve to electric stimulation","volume":"81","author":"Killian","year":"1994","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2007.07.001_bib28","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/0378-5955(82)90076-4","article-title":"Deaf animal models for studies of a multichannel cochlear prosthesis","volume":"8","author":"Leake-Jones","year":"1982","journal-title":"Hear. Res."},{"issue":"1","key":"10.1016\/j.heares.2007.07.001_bib29","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1121\/1.1375140","article-title":"Auditory nerve fiber responses to electric stimulation: modulated and unmodulated pulse trains","volume":"110","author":"Litvak","year":"2001","journal-title":"J. Acoust. Soc. Am."},{"issue":"4","key":"10.1016\/j.heares.2007.07.001_bib30","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1121\/1.1612492","article-title":"Desynchronization of electrically evoked auditory-nerve activity by high-frequency pulse trains of long duration","volume":"114","author":"Litvak","year":"2003","journal-title":"J. Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2007.07.001_bib31","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0378-5955(00)00172-6","article-title":"The neuronal response to electrical constant-amplitude pulse train stimulation: evoked compound action potential recordings","volume":"149","author":"Matsuoka","year":"2000","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2007.07.001_bib32","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/S0378-5955(98)00046-X","article-title":"Electrically evoked compound action potentials of guinea pig and cat: responses to monopolar, monophasic stimulation","volume":"119","author":"Miller","year":"1998","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2007.07.001_bib33","unstructured":"Miller, C.A., Abbas, P.J., Rubinstein, J.T., Runge-Samuelson, C., Robinson, B.K., 2000. Effects of remaining hair cells on cochlear implant function. Fifth Quarterly Progress Report, Neural Prosthesis Program contract N01-DC-9-2106 NIH."},{"issue":"3","key":"10.1016\/j.heares.2007.07.001_bib34","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1007\/s101620010083","article-title":"Response properties of the refractory auditory nerve fiber","volume":"2","author":"Miller","year":"2001","journal-title":"J. Assoc. Res. Otolaryngol."},{"key":"10.1016\/j.heares.2007.07.001_bib35","unstructured":"Miller, C.A., Abbas, P.J., Hu, N., Robinson, B.K., 2003. Effects of remaining hair cells on cochlear implant function. Second Quarterly Progress Report, Neural Prosthesis Program contract N01-DC-2-1005 NIH."},{"key":"10.1016\/j.heares.2007.07.001_bib36","unstructured":"Miller, C.A., Abbas, P.J., Noh, H., Robinson, B.K., Nourski, K.V., 2004. Effects of remaining hair cells on cochlear implant function. Ninth Quarterly Progress Report, Neural Prosthesis Program contract N01-DC-2-1005 NIH."},{"key":"10.1016\/j.heares.2007.07.001_bib37","unstructured":"Miller, C., Noh, H., Abbas, P., Robinson, B., Nourski, K., Jeng, F.C., 2005a. Effects of combined acoustic and electric stimuli: single auditory nerve fiber responses. Assoc. Res. Otolaryngol. 2005 MidWinter Meeting. February 19\u201324, 2005, New Orleans, LA, USA, p. 357."},{"key":"10.1016\/j.heares.2007.07.001_bib38","unstructured":"Miller, C.A., Robinson, B.K., Abbas, P.J., Nourski, K.V., Jeng, F.C., 2005b. Effects of remaining hair cells on cochlear implant function. Twelfth Quarterly Progress Report, Neural Prosthesis Program contract N01-DC-2-1005 NIH."},{"key":"10.1016\/j.heares.2007.07.001_bib39","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s10162-006-0036-9","article-title":"Electrical excitation of the acoustically sensitive auditory nerve: single-fiber responses to electric pulse trains","volume":"7","author":"Miller","year":"2006","journal-title":"J. Assoc. Res. Otolaryngol."},{"key":"10.1016\/j.heares.2007.07.001_bib40","unstructured":"Moxon, E.C., 1971. Neural and mechanical responses to electric stimulation of the cat\u2019s inner ear. Ph.D. dissertation. Massachusetts Institute of Technology, Boston, MA, USA."},{"key":"10.1016\/j.heares.2007.07.001_bib41","unstructured":"NIH Consensus Statement, 1995. Cochlear implants in adults and children. NIH Consensus Statement 13(2), pp. 1\u201330."},{"key":"10.1016\/j.heares.2007.07.001_bib42","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.heares.2004.10.001","article-title":"Effects of acoustic noise on the auditory nerve compound action potentials evoked by electric pulse trains","volume":"202","author":"Nourski","year":"2005","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2007.07.001_bib43","unstructured":"Nourski, K.V., Abbas, P.J., Miller, C.A., Robinson, B.K., Noh, H., 2005b. Acoustic\u2013electric interactions in the auditory nerve: masking of the electrically-evoked compound action potential by acoustic noise. 2005 Conference on Implantable Auditory Prostheses. July 30\u2013August 4, 2005, Pacific Grove, CA, USA, p. 102."},{"key":"10.1016\/j.heares.2007.07.001_bib44","unstructured":"Nourski, K., Abbas, P., Noh, H., Miller, C., Robinson, B., 2005c. Acoustic and electric interactions in the auditory nerve: simultaneous and forward masking of the electrically-evoked compound action potential. Assoc. Res. Otolaryngol. 2005 MidWinter Meeting. February 19\u201324, 2005, New Orleans, LA, USA. Assoc. Res. Otolaryngol. Abs.: 28."},{"key":"10.1016\/j.heares.2007.07.001_bib45","unstructured":"Nourski, K., Abbas, P., Miller, C., Robinson, B., Jeng, F.-C., 2006. Forward masking of the electrically evoked compound action potential in animals with residual hair cell function. Assoc. Res. Otolaryngol. 2006 MidWinter Meeting. February 5\u20139, 2006, Baltimore, MD, USA. Assoc. Res. Otolaryngol. Abs.: 934."},{"key":"10.1016\/j.heares.2007.07.001_bib46","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0378-5955(80)90009-X","article-title":"The time course of strial changes produced by intravenous furosemide","volume":"3","author":"Pike","year":"1980","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2007.07.001_bib47","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/S0378-5955(98)00185-3","article-title":"Pseudospontaneous activity: stochastic independence of auditory nerve fibers with electrical stimulation","volume":"127","author":"Rubinstein","year":"1999","journal-title":"Hear. Res."},{"issue":"4","key":"10.1016\/j.heares.2007.07.001_bib48","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1523\/JNEUROSCI.11-04-01057.1991","article-title":"Furosemide alters Organ of Corti mechanics: evidence for feedback of outer hair cells upon the basilar membrane","volume":"11","author":"Ruggero","year":"1991","journal-title":"J. Neurosci."},{"key":"10.1016\/j.heares.2007.07.001_bib49","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.heares.2004.02.006","article-title":"Ensemble spontaneous activity in the guinea-pig cochlear nerve","volume":"192","author":"Searchfield","year":"2004","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2007.07.001_bib50","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/0378-5955(84)90057-1","article-title":"The effects of furosemide on the endocochlear potential and auditory-nerve fiber tuning curves in cats","volume":"14","author":"Sewell","year":"1984","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2007.07.001_bib51","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1113\/jphysiol.1984.sp015090","article-title":"The relation between the endocochlear potential and spontaneous activity in auditory nerve fibres of the cat","volume":"347","author":"Sewell","year":"1984","journal-title":"J. Physiol."},{"key":"10.1016\/j.heares.2007.07.001_bib52","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-5955(01)00224-6","article-title":"Differential vulnerability of basal and apical hair cells is based on intrinsic susceptibility to free radicals","volume":"155","author":"Sha","year":"2001","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2007.07.001_bib53","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/S0378-5955(97)00046-4","article-title":"Electrical stimulation of the auditory nerve. I. Correlation of physiological responses with cochlear status","volume":"108","author":"Shepherd","year":"1997","journal-title":"Hear. Res."},{"issue":"4","key":"10.1016\/j.heares.2007.07.001_bib54","first-page":"CS26","article-title":"A new method of partial deafness treatment","volume":"9","author":"Skar\u017cy\u0144ski","year":"2003","journal-title":"Med. Sci. Monit."},{"issue":"9","key":"10.1016\/j.heares.2007.07.001_bib55","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1080\/00016480600606632","article-title":"Partial deafness cochlear implantation provides benefit to a new population of individuals with hearing loss","volume":"126","author":"Skar\u017cy\u0144ski","year":"2006","journal-title":"Acta Otolaryngol."},{"issue":"5","key":"10.1016\/j.heares.2007.07.001_bib56","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1152\/jn.1977.40.5.1098","article-title":"Short-term adaptation in single auditory nerve fibers: some poststimulatory effects","volume":"40","author":"Smith","year":"1977","journal-title":"J. Neurophysiol."},{"issue":"4","key":"10.1016\/j.heares.2007.07.001_bib57","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1121\/1.1687425","article-title":"Speech recognition in noise for cochlear implant listeners: benefits of residual acoustic hearing","volume":"115","author":"Turner","year":"2004","journal-title":"J. Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2007.07.001_bib58","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0378-5955(84)90032-7","article-title":"Rapid and short-term adaptation in auditory nerve responses","volume":"15","author":"Westerman","year":"1984","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2007.07.001_bib59","unstructured":"Wilson, B., Wolford, R., Lawson, D., Schatzer, R., 2002. Speech processors for auditory prostheses. Third Quarterly Progress Report, Neural Prosthesis Program contract N01-DC-2-1002 NIH."},{"key":"10.1016\/j.heares.2007.07.001_bib60","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1146\/annurev.bioeng.5.040202.121645","article-title":"Cochlear implants: some likely next steps","volume":"5","author":"Wilson","year":"2003","journal-title":"Annu. Rev. Biomed. Eng."}],"container-title":["Hearing Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595507001748?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595507001748?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,30]],"date-time":"2019-04-30T20:52:20Z","timestamp":1556657540000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378595507001748"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,10]]},"references-count":60,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2007,10]]}},"alternative-id":["S0378595507001748"],"URL":"https:\/\/doi.org\/10.1016\/j.heares.2007.07.001","relation":{},"ISSN":["0378-5955"],"issn-type":[{"value":"0378-5955","type":"print"}],"subject":[],"published":{"date-parts":[[2007,10]]}}}