{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T17:36:50Z","timestamp":1790530610043,"version":"4.1.0"},"reference-count":52,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hearing Research"],"published-print":{"date-parts":[[2008,8]]},"DOI":"10.1016\/j.heares.2008.03.005","type":"journal-article","created":{"date-parts":[[2008,4,8]],"date-time":"2008-04-08T12:28:54Z","timestamp":1207657734000},"page":"154-163","source":"Crossref","is-referenced-by-count":56,"title":["Alternative pulse shapes in electrical hearing"],"prefix":"10.1016","volume":"242","author":[{"given":"Astrid","family":"van Wieringen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Macherey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert P.","family":"Carlyon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John M.","family":"Deeks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Wouters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.heares.2008.03.005_bib1","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1121\/1.2436712","article-title":"Threshold and channel interaction in cochlear implant users: evaluation of the tripolar electrode configuration","volume":"121","author":"Bierer","year":"2007","journal-title":"J. Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2008.03.005_bib2","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1080\/00016480410031084","article-title":"Speech recognition with a cochlear implant using triphasic charge-balanced pulses","volume":"124","author":"Bonnet","year":"2004","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.heares.2008.03.005_bib3","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1121\/1.399716","article-title":"Electrically evoked whole-nerve action potentials: data from human cochlear implant users","volume":"88","author":"Brown","year":"1990","journal-title":"J. Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2008.03.005_bib4","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1109\/TBME.1977.326218","article-title":"Electrochemical considerations for safe electrical stimulation of the nervous system with platinum electrodes","volume":"24","author":"Brummer","year":"1977","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"10.1016\/j.heares.2008.03.005_bib5","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.heares.2005.03.021","article-title":"Effect of inter-phase gap on the sensitivity of cochlear implant users to electrical stimulation","volume":"205","author":"Carlyon","year":"2005","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2008.03.005_bib6","doi-asserted-by":"crossref","first-page":"100S","DOI":"10.1097\/AUD.0b013e31803150f4","article-title":"The totally implantable cochlear implant","volume":"28","author":"Cohen","year":"2007","journal-title":"Ear Hear."},{"key":"10.1016\/j.heares.2008.03.005_bib7","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0378-5955(87)90197-3","article-title":"A model of electrical excitation of the mammalian auditory-nerve neuron","volume":"31","author":"Colombo","year":"1987","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2008.03.005_bib8","doi-asserted-by":"crossref","first-page":"3099","DOI":"10.1121\/1.414796","article-title":"Stimulus features affecting psychophysical detection thresholds for electrical stimulation of the cochlea. III. Pulse polarity","volume":"99","author":"Coste","year":"1996","journal-title":"J. Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2008.03.005_bib9","unstructured":"Eddington, D.K., Tierney, J., Noel, V., Hermann, B., Whearty, M., Finley, C.C., 2004. Speech processors for auditory prostheses. Ninth Quarterly Progress Report, NIH contract N01-DC-2-1001."},{"key":"10.1016\/j.heares.2008.03.005_bib10","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1097\/01.mlg.0000227176.09500.28","article-title":"Multichannel cochlear implants: relation of histopathology to performance","volume":"116","author":"Fayad","year":"2006","journal-title":"Laryngoscope"},{"key":"10.1016\/j.heares.2008.03.005_bib11","series-title":"Cochlear Implants: Models of the Electrically Stimulated Ear","first-page":"55","article-title":"Models of neural responsiveness to electrical stimulation","author":"Finley","year":"1990"},{"key":"10.1016\/j.heares.2008.03.005_bib12","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0378-5955(96)00004-4","article-title":"Spatial selectivity in a rotationally symmetric model of the electrically stimulated cochlea","volume":"95","author":"Frijns","year":"1996","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2008.03.005_bib13","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1109\/51.395310","article-title":"Stimulus waveforms for selective neural stimulation","volume":"14","author":"Grill","year":"1995","journal-title":"IEEE Eng. Med. Biol."},{"key":"10.1016\/j.heares.2008.03.005_bib14","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1109\/10.481985","article-title":"The effect of stimulus pulse duration on selectivity of neural stimulation","volume":"43","author":"Grill","year":"1996","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"10.1016\/j.heares.2008.03.005_bib15","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0378-5955(84)90094-7","article-title":"Discharge patterns of cat primary auditory fibers with electrical stimulation of the cochlea","volume":"13","author":"Hartmann","year":"1984","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2008.03.005_bib16","unstructured":"Macherey, O., 2007. Effects of stimulus waveform on hearing with cochlear implants: psychophysics, modeling and objective measures. PhD Dissertation, KULeuven."},{"key":"10.1016\/j.heares.2008.03.005_bib17","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s10162-006-0040-0","article-title":"Asymmetric pulses in cochlear implants: effects of pulse shape, polarity, and rate","volume":"7","author":"Macherey","year":"2006","journal-title":"J. Assoc. Res. Otolaryngol."},{"key":"10.1016\/j.heares.2008.03.005_bib18","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1007\/s10162-006-0066-3","article-title":"A dual-process integrator-resonator model of the electrically stimulated human auditory nerve","volume":"8","author":"Macherey","year":"2007","journal-title":"J. Assoc. Res. Otolaryngol."},{"key":"10.1016\/j.heares.2008.03.005_bib19","first-page":"4","article-title":"Higher sensitivity of human auditory nerve fibers to positive electrical currents","volume":"5","author":"Macherey","year":"2008","journal-title":"J. Assoc. Res. Otolaryngol."},{"key":"10.1016\/j.heares.2008.03.005_bib20","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1121\/1.428052","article-title":"The perceptual effects of current pulse duration in electrical stimulation of the auditory nerve","volume":"106","author":"McKay","year":"1999","journal-title":"J. Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2008.03.005_bib21","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/S0378-5955(03)00177-1","article-title":"The perceptual effects of interphase gap duration in cochlear implant stimulation","volume":"181","author":"McKay","year":"2003","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2008.03.005_bib22","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/S0006-3495(99)77251-6","article-title":"Excitation of central nervous system neurons by nonuniform electric fields","volume":"76","author":"McIntyre","year":"1999","journal-title":"Biophys. J."},{"key":"10.1016\/j.heares.2008.03.005_bib23","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1114\/1.262","article-title":"Selective microstimulation of central nervous system neurons","volume":"28","author":"McIntyre","year":"2000","journal-title":"Ann. Biomed. Eng."},{"key":"10.1016\/j.heares.2008.03.005_bib24","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1152\/jn.2002.88.4.1592","article-title":"Extracellular stimulation of central neurons: influence of stimulus waveform and frequency on neuronal output?","volume":"88","author":"McIntyre","year":"2002","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.heares.2008.03.005_bib25","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1097\/01.mao.0000185060.74339.9d","article-title":"Speech perception with mono- and quadrupolar electrode configurations: a crossover study","volume":"26","author":"Mens","year":"2005","journal-title":"Otol. Neurotol."},{"key":"10.1016\/j.heares.2008.03.005_bib26","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/0378-5955(95)00205-7","article-title":"Functional responses from guinea pigs with cochlear implants. II. Changes in electrophysiological and psychophysical measures over time","volume":"92","author":"Miller","year":"1995","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2008.03.005_bib27","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/S0378-5955(98)00046-X","article-title":"Electrically evoked compound action potentials of guinea pig and cat: responses to monopolar, monophasic stimulation","volume":"119","author":"Miller","year":"1998","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2008.03.005_bib28","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0378-5955(99)00012-X","article-title":"Electrically evoked single-fiber action potentials from cat: responses to monopolar, monophasic stimulation","volume":"130","author":"Miller","year":"1999","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2008.03.005_bib29","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0300-2977(00)00082-6","article-title":"Auditory nerve responses to monophasic and biphasic electric stimuli","volume":"151","author":"Miller","year":"2001","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2008.03.005_bib30","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.heares.2004.07.005","article-title":"Intracochlear and extracochlear ECAPs suggest antidromic action potentials","volume":"198","author":"Miller","year":"2004","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2008.03.005_bib31","doi-asserted-by":"crossref","first-page":"2393","DOI":"10.1121\/1.417949","article-title":"Intensity discrimination as a function of stimulus level with electric stimulation","volume":"100","author":"Nelson","year":"1996","journal-title":"J. Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2008.03.005_bib32","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/0378-5955(88)90005-6","article-title":"Comparisons of psychophysical and neurophysiological studies of cochlear implants","volume":"34","author":"Pfingst","year":"1988","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2008.03.005_bib33","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.heares.2006.03.006","article-title":"Effect of interphase gap and pulse duration on electrically evoked potentials is correlated with auditory nerve survival","volume":"215","author":"Prado-Guitierrez","year":"2006","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2008.03.005_bib34","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/0006-8993(75)90364-9","article-title":"Which elements are excited in electrical stimulation of mammalian central nervous system: a review","volume":"98","author":"Ranck","year":"1975","journal-title":"Brain Res."},{"key":"10.1016\/j.heares.2008.03.005_bib35","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1109\/10.32099","article-title":"Analysis of models for extracellular fiber stimulation","volume":"36","author":"Rattay","year":"1989","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"10.1016\/j.heares.2008.03.005_bib36","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0306-4522(98)00330-3","article-title":"The basic mechanism for the electrical stimulation of the nervous system","volume":"89","author":"Rattay","year":"1999","journal-title":"Neuroscience"},{"key":"10.1016\/j.heares.2008.03.005_bib37","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0378-5955(00)00256-2","article-title":"A model of the electrically excited human cochlear neuron. I. Contribution of neural substructures to the generation and propagation of spikes","volume":"153","author":"Rattay","year":"2001","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2008.03.005_bib38","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S0378-5955(00)00257-4","article-title":"A model of the electrically excited human cochlear neuron. II. Influence of the three-dimensional cochlear structure on neural excitability","volume":"153","author":"Rattay","year":"2001","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2008.03.005_bib39","series-title":"Neural Prostheses: Fundamental Studies","first-page":"25","article-title":"Electrochemical guidelines for selection of protocols and electrode materials for neural stimulation","author":"Robblee","year":"1990"},{"key":"10.1016\/j.heares.2008.03.005_bib40","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1109\/10.237695","article-title":"Axon termination conditions for electrical stimulation","volume":"40","author":"Rubinstein","year":"1993","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"10.1016\/j.heares.2008.03.005_bib41","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1109\/10.951508","article-title":"Analysis of monophasic and biphasic electrical stimulation of nerve","volume":"48","author":"Rubinstein","year":"2001","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"10.1016\/j.heares.2008.03.005_bib42","series-title":"Neuroprosthetics: Theory and Practice","article-title":"Cochlear implants","author":"Seligman","year":"2004"},{"key":"10.1016\/j.heares.2008.03.005_bib43","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/0378-5955(85)90005-X","article-title":"Threshold and loudness functions for pulsatile stimulation of cochlear implants","volume":"18","author":"Shannon","year":"1985","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2008.03.005_bib44","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0378-5955(89)90160-3","article-title":"A model of threshold for pulsatile electrical stimulation of cochlear implants","volume":"40","author":"Shannon","year":"1989","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2008.03.005_bib45","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0378-5955(99)00011-8","article-title":"Electrical stimulation of the auditory nerve. II. Effect of stimulus waveshape on single fibre response properties","volume":"130","author":"Shepherd","year":"1999","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2008.03.005_bib46","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1080\/00016489950180621","article-title":"Chronic electrical stimulation o the auditory nerve using non-charge-balanced stimuli","volume":"119","author":"Shepherd","year":"1999","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.heares.2008.03.005_bib47","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/BF02363130","article-title":"The response of the myelinated nerve fiber to short duration biphasic stimulating currents","volume":"7","author":"van den Honert","year":"1979","journal-title":"Ann. Biomed. Eng."},{"key":"10.1016\/j.heares.2008.03.005_bib48","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/0378-5955(87)90168-7","article-title":"Temporal response patterns of single auditory nerve fibers elicited by periodic electrical stimuli","volume":"29","author":"van den Honert","year":"1987","journal-title":"Hear. Res."},{"issue":"6","key":"10.1016\/j.heares.2008.03.005_bib49","doi-asserted-by":"crossref","first-page":"3703","DOI":"10.1121\/1.2722047","article-title":"Focused intracochlear electric stimulation with phased array channels","volume":"121","author":"van den Honert","year":"2007","journal-title":"J. Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2008.03.005_bib50","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.heares.2004.08.006","article-title":"Effects of waveform shape on human sensitivity to electrical stimulation of the inner ear","volume":"200","author":"van Wieringen","year":"2005","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2008.03.005_bib51","unstructured":"van Wieringen, A., Carlyon, R.P., Wouters, J., 2005b. Spatial excitation patterns of different pulse shapes and electrode configurations in cochlear implantees, 2005. In: Conference on Implantable Auditory Prostheses, July 31\u2013August 4, Asilomar, California, USA."},{"key":"10.1016\/j.heares.2008.03.005_bib52","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.heares.2006.06.015","article-title":"Effects of pulse rate on thresholds and loudness of biphasic and alternating monophasic pulse trains in electrical hearing","volume":"220","author":"van Wieringen","year":"2006","journal-title":"Hear. Res."}],"container-title":["Hearing Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595508000622?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595508000622?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T21:16:02Z","timestamp":1557436562000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378595508000622"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8]]},"references-count":52,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["S0378595508000622"],"URL":"https:\/\/doi.org\/10.1016\/j.heares.2008.03.005","relation":{},"ISSN":["0378-5955"],"issn-type":[{"value":"0378-5955","type":"print"}],"subject":[],"published":{"date-parts":[[2008,8]]}}}