{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T23:51:26Z","timestamp":1789343486634,"version":"build-2803163510"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"University of Auckland Faculty Research Development Fund"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hearing Research"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1016\/j.heares.2013.07.012","type":"journal-article","created":{"date-parts":[[2013,7,27]],"date-time":"2013-07-27T21:46:35Z","timestamp":1374961595000},"page":"145-152","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"special_numbering":"C","title":["Noise-induced changes in expression levels of NADPH oxidases in the cochlea"],"prefix":"10.1016","volume":"304","author":[{"given":"Srdjan M.","family":"Vlajkovic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shelly Ching-yu","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann Chi Yan","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brad","family":"Wackrow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter R.","family":"Thorne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.heares.2013.07.012_bib1","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1161\/01.CIR.0000105680.92873.70","article-title":"Nox4 as the major catalytic component of an endothelial NAD(P)H oxidase","volume":"109","author":"Ago","year":"2004","journal-title":"Circulation"},{"issue":"44","key":"10.1016\/j.heares.2013.07.012_bib2","doi-asserted-by":"crossref","first-page":"46065","DOI":"10.1074\/jbc.M403046200","article-title":"NOX3, a superoxide generating NADPH oxidase of the inner ear","volume":"279","author":"Banfi","year":"2004","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.heares.2013.07.012_bib3","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1152\/physrev.00044.2005","article-title":"The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology","volume":"87","author":"Bedard","year":"2007","journal-title":"Physiological Reviews"},{"issue":"33","key":"10.1016\/j.heares.2013.07.012_bib4","doi-asserted-by":"crossref","first-page":"34250","DOI":"10.1074\/jbc.M400660200","article-title":"Nox3 regulation by NOXO1, p47phox, and p67phox","volume":"279","author":"Cheng","year":"2004","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.heares.2013.07.012_bib5","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1042\/bj2370111","article-title":"The effect of the inhibitor diphenylene iodonium of the superoxide-generating system of neutrophils","volume":"237","author":"Cross","year":"1986","journal-title":"Biochemical Journal"},{"issue":"5","key":"10.1016\/j.heares.2013.07.012_bib6","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1021\/bi9020378","article-title":"Signaling functions of reactive oxygen species","volume":"49","author":"Forman","year":"2010","journal-title":"Biochemistry"},{"issue":"2","key":"10.1016\/j.heares.2013.07.012_bib7","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0378-5955(84)90004-2","article-title":"Surface morphology of the inner sulcus and related epithelial cells of the cochlea following acoustic trauma","volume":"16","author":"Hamernik","year":"1984","journal-title":"Hearing Research"},{"issue":"1","key":"10.1016\/j.heares.2013.07.012_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/01.aud.0000191942.36672.f3","article-title":"The role of oxidative stress in noise-induced hearing loss","volume":"27","author":"Henderson","year":"2006","journal-title":"Ear & Hearing"},{"issue":"9\u201310","key":"10.1016\/j.heares.2013.07.012_bib9","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1089\/ars.2006.8.1583","article-title":"NADPH oxidases of the brain: distribution, regulation, and function","volume":"8","author":"Infanger","year":"2006","journal-title":"Antioxidants & Redox Signaling"},{"issue":"3","key":"10.1016\/j.heares.2013.07.012_bib10","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1161\/01.RES.87.3.179","article-title":"Oxidant signaling in vascular cell growth, death, and survival: a review of the roles of reactive oxygen species in smooth muscle and endothelial cell mitogenic and apoptotic signaling","volume":"87","author":"Irani","year":"2000","journal-title":"Circulation Research"},{"issue":"11","key":"10.1016\/j.heares.2013.07.012_bib11","doi-asserted-by":"crossref","first-page":"3000","DOI":"10.1161\/STROKEAHA.107.489765","article-title":"NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke","volume":"38","author":"Kahles","year":"2007","journal-title":"Stroke"},{"issue":"36","key":"10.1016\/j.heares.2013.07.012_bib12","doi-asserted-by":"crossref","first-page":"31859","DOI":"10.1074\/jbc.M501882200","article-title":"Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation","volume":"280","author":"Kawahara","year":"2005","journal-title":"Journal of Biological Chemistry"},{"issue":"11","key":"10.1016\/j.heares.2013.07.012_bib13","doi-asserted-by":"crossref","first-page":"3933","DOI":"10.1523\/JNEUROSCI.6054-09.2010","article-title":"Roles of NADPH oxidases in cisplatin-induced reactive oxygen species generation and ototoxicity","volume":"30","author":"Kim","year":"2010","journal-title":"Journal of Neuroscience"},{"issue":"8","key":"10.1016\/j.heares.2013.07.012_bib14","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1517\/13543776.2011.584870","article-title":"NADPH oxidase inhibitors: a patent review","volume":"21","author":"Kim","year":"2011","journal-title":"Expert Opinion on Therapeutic Patents"},{"key":"10.1016\/j.heares.2013.07.012_bib15","first-page":"S28","article-title":"Tissue distribution and putative physiological function of NOX family NADPH oxidases","volume":"57","author":"Krause","year":"2004","journal-title":"Japanese Journal of Infectious Diseases"},{"issue":"1\u20132","key":"10.1016\/j.heares.2013.07.012_bib16","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.heares.2006.10.006","article-title":"Mechanisms of noise-induced hearing loss indicate multiple methods of prevention","volume":"226","author":"Le Prell","year":"2007","journal-title":"Hearing Research"},{"key":"10.1016\/j.heares.2013.07.012_bib17","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"issue":"2","key":"10.1016\/j.heares.2013.07.012_bib18","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/j.neuroscience.2005.12.044","article-title":"Expression of the kidney injury molecule 1 in the rat cochlea and induction by cisplatin","volume":"139","author":"Mukherjea","year":"2006","journal-title":"Neuroscience"},{"issue":"5","key":"10.1016\/j.heares.2013.07.012_bib19","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1089\/ars.2010.3110","article-title":"Transtympanic administration of short interfering (si)RNA for the NOX3 isoform of NADPH oxidase protects against cisplatin-induced hearing loss in the rat","volume":"13","author":"Mukherjea","year":"2010","journal-title":"Antioxidants & Redox Signaling"},{"issue":"1","key":"10.1016\/j.heares.2013.07.012_bib20","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1042\/BJ20060819","article-title":"Critical roles for p22phox in the structural maturation and subcellular targeting of Nox3","volume":"403","author":"Nakano","year":"2007","journal-title":"Biochemical Journal"},{"issue":"2","key":"10.1016\/j.heares.2013.07.012_bib21","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1517\/14728214.2011.552427","article-title":"Emerging treatments for noise-induced hearing loss","volume":"16","author":"Oishi","year":"2011","journal-title":"Expert Opinion on Emerging Drugs"},{"issue":"5","key":"10.1016\/j.heares.2013.07.012_bib22","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1101\/gad.1172504","article-title":"Vestibular defects in head-tilt mice result from mutations in Nox3, encoding an NADPH oxidase","volume":"18","author":"Paffenholz","year":"2004","journal-title":"Genes & Development"},{"issue":"14","key":"10.1016\/j.heares.2013.07.012_bib23","doi-asserted-by":"crossref","first-page":"2429","DOI":"10.1007\/s00018-012-1016-3","article-title":"siRNA-mediated knock-down of NOX3: therapy for hearing loss?","volume":"69","author":"Rybak","year":"2012","journal-title":"Cellular and Molecular Life Sciences"},{"issue":"5\u20136","key":"10.1016\/j.heares.2013.07.012_bib24","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.vph.2012.02.012","article-title":"Targeting NADPH oxidases in vascular pharmacology","volume":"56","author":"Schramm","year":"2012","journal-title":"Vascular Pharmacology"},{"issue":"1280","key":"10.1016\/j.heares.2013.07.012_bib25","first-page":"33","article-title":"Epidemiology of noise-induced hearing loss in New Zealand","volume":"121","author":"Thorne","year":"2008","journal-title":"New Zealand Medical Journal"},{"issue":"24","key":"10.1016\/j.heares.2013.07.012_bib26","doi-asserted-by":"crossref","first-page":"23328","DOI":"10.1074\/jbc.M414548200","article-title":"The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators","volume":"280","author":"Ueno","year":"2005","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.heares.2013.07.012_bib27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-5955(02)00279-4","article-title":"K+ cycling and the endocochlear potential","volume":"165","author":"Wangemann","year":"2002","journal-title":"Hearing Research"},{"key":"10.1016\/j.heares.2013.07.012_bib29","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.heares.2009.12.004","article-title":"A1 adenosine receptor agonists attenuate noise-induced hearing loss","volume":"260","author":"Wong","year":"2010","journal-title":"Hearing Research"},{"key":"10.1016\/j.heares.2013.07.012_bib30","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1007\/s00418-012-0922-7","article-title":"Expression and distribution of creatine transporter and creatine kinase (brain isoform) in developing and mature rat cochlear tissues","volume":"137","author":"Wong","year":"2012","journal-title":"Histochemistry and Cell Biology"},{"key":"10.1016\/j.heares.2013.07.012_bib31","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.brainres.2004.05.104","article-title":"Delayed production of free radicals following noise exposure","volume":"1019","author":"Yamashita","year":"2004","journal-title":"Brain Research"},{"issue":"2","key":"10.1016\/j.heares.2013.07.012_bib32","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.neuroscience.2005.04.015","article-title":"Post-exposure treatment attenuates noise-induced hearing loss","volume":"134","author":"Yamashita","year":"2005","journal-title":"Neuroscience"}],"container-title":["Hearing Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595513001834?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595513001834?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,14]],"date-time":"2018-10-14T08:51:10Z","timestamp":1539507070000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378595513001834"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":31,"alternative-id":["S0378595513001834"],"URL":"https:\/\/doi.org\/10.1016\/j.heares.2013.07.012","relation":{},"ISSN":["0378-5955"],"issn-type":[{"value":"0378-5955","type":"print"}],"subject":[],"published":{"date-parts":[[2013,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Noise-induced changes in expression levels of NADPH oxidases in the cochlea","name":"articletitle","label":"Article Title"},{"value":"Hearing Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.heares.2013.07.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}