{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T06:06:34Z","timestamp":1788588394162,"version":"build-2803163510"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000297","name":"The Royal College of Surgeons of England","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000297","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Midland Institute of Otology"},{"DOI":"10.13039\/501100000828","name":"Royal Society of Medicine","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000828","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Otorhinolaryngological Research Society"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hearing Research"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1016\/j.heares.2014.03.005","type":"journal-article","created":{"date-parts":[[2014,3,21]],"date-time":"2014-03-21T10:33:58Z","timestamp":1395398038000},"page":"81-90","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Cochlear implantation in the mouse via the round window: Effects of\u00a0array insertion"],"prefix":"10.1016","volume":"312","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9972-0723","authenticated-orcid":false,"given":"N.","family":"Mistry","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.S.","family":"Nolan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.R.","family":"Saeed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Forge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.R.","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl.\u00a02","key":"10.1016\/j.heares.2014.03.005_bib1","doi-asserted-by":"crossref","first-page":"S36","DOI":"10.1179\/146701011X13074645127478","article-title":"Cochlear implant electrode insertion: in defence of cochleostomy and factors against the round window membrane approach","volume":"12","author":"Addams-Williams","year":"2011","journal-title":"Cochl. Implan. Int."},{"key":"10.1016\/j.heares.2014.03.005_bib2","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1159\/000145683","article-title":"The stapedial artery in the rat. A microscopical study under normal conditions and in otitis media with effusion","volume":"115","author":"Albiin","year":"1983","journal-title":"Acta Anat. (Basel)"},{"key":"10.1016\/j.heares.2014.03.005_bib3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/ar.1092120103","article-title":"The vascular supply of the rat tympanic membrane","volume":"212","author":"Albiin","year":"1985","journal-title":"Anat. Rec."},{"issue":"2","key":"10.1016\/j.heares.2014.03.005_bib40","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.neuron.2012.05.019","article-title":"Restoration of hearing in the VGLUT3 knockout mouse using virally mediated gene therapy","volume":"75","author":"Akil","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.heares.2014.03.005_bib4","article-title":"Imaging in cochlear implant patients","volume":"10","author":"Aschendorff","year":"2011","journal-title":"GMS. Curr. Top. Otorhinolaryngol. Head. Neck Surg."},{"key":"10.1016\/j.heares.2014.03.005_bib5","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.jneumeth.2007.09.016","article-title":"Microsurgical access for cell injection into the mammalian cochlea","volume":"168","author":"Bogaerts","year":"2008","journal-title":"J.\u00a0Neurosci. Meth."},{"key":"10.1016\/j.heares.2014.03.005_bib6","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1177\/000348940511400709","article-title":"Cochlear wall erosion after cochlear implantation","volume":"114","author":"Cervera-Paz","year":"2005","journal-title":"Ann. Otol. Rhinol. Laryngol."},{"key":"10.1016\/j.heares.2014.03.005_bib7","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.jneumeth.2005.05.017","article-title":"A\u00a0method for intracochlear drug delivery in the mouse","volume":"150","author":"Chen","year":"2006","journal-title":"J.\u00a0Neurosci. Meth."},{"key":"10.1016\/j.heares.2014.03.005_bib8","first-page":"42","article-title":"Experimental animal model of intracochlear ossification in relation to cochlear implantation","volume":"166","author":"Chow","year":"1995","journal-title":"Ann. Otol. Rhinol. Laryngol. Suppl."},{"key":"10.1016\/j.heares.2014.03.005_bib9","first-page":"40","article-title":"Cochlear implantation: osteoneogenesis, electrode-tissue impedance, and residual hearing","volume":"166","author":"Clark","year":"1995","journal-title":"Ann. Otol. Rhinol. Laryngol. Suppl."},{"key":"10.1016\/j.heares.2014.03.005_bib10","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1586\/erd.11.12","article-title":"Cochlear implants: current status and future potential","volume":"8","author":"Cosetti","year":"2011","journal-title":"Expert. Rev. Med. Dev."},{"key":"10.1016\/j.heares.2014.03.005_bib11","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1097\/AUD.0b013e3182498c28","article-title":"Electrophysiological properties of cochlear implantation in the gerbil using a flexible array","volume":"33","author":"DeMason","year":"2012","journal-title":"Ear Hear"},{"key":"10.1016\/j.heares.2014.03.005_bib12","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.otohns.2009.03.031","article-title":"Histopathologic assessment of fibrosis and new bone formation in implanted human temporal bones using 3D reconstruction","volume":"141","author":"Fayad","year":"2009","journal-title":"Otolaryngol. Head. Neck Surg."},{"key":"10.1016\/j.heares.2014.03.005_bib13","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1177\/1084713809336422","article-title":"Soft cochlear implantation: rationale for the surgical approach","volume":"13","author":"Friedland","year":"2009","journal-title":"Trends Amplif."},{"key":"10.1016\/j.heares.2014.03.005_bib14","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1177\/000348949310200914","article-title":"Persistent stapedial artery: does it prevent successful surgery?","volume":"102","author":"Govaerts","year":"1993","journal-title":"Ann. Otol. Rhinol. Laryngol."},{"key":"10.1016\/j.heares.2014.03.005_bib15","first-page":"43","article-title":"Surgical techniques for cell transplantation into the mouse cochlea","author":"Iguchi","year":"2004","journal-title":"Acta Otolaryngol. Suppl."},{"key":"10.1016\/j.heares.2014.03.005_bib16","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/S0378-5955(00)00216-1","article-title":"A\u00a0surgical approach appropriate for targeted cochlear gene therapy in the mouse","volume":"151","author":"Jero","year":"2001","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2014.03.005_bib17","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1080\/00016489850183386","article-title":"Intracochlear factors contributing to psychophysical percepts following cochlear implantation","volume":"118","author":"Kawano","year":"1998","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.heares.2014.03.005_bib18","doi-asserted-by":"crossref","first-page":"116","DOI":"10.3109\/00016489.2011.626794","article-title":"Evaluation of the implanted cochlear implant electrode by CT scanning with three-dimensional reconstruction","volume":"132","author":"Kong","year":"2012","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.heares.2014.03.005_bib19","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1001\/archotol.130.5.499","article-title":"An animal model for cochlear implants","volume":"130","author":"Kretzmer","year":"2004","journal-title":"Arch. Otolaryngol. Head. Neck Surg."},{"issue":"Suppl.\u00a01","key":"10.1016\/j.heares.2014.03.005_bib20","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1159\/000206492","article-title":"Hearing conservation surgery using the Hybrid-L electrode. Results from the first clinical trial at the Medical University of Hannover","volume":"14","author":"Lenarz","year":"2009","journal-title":"Audiol. Neurootol"},{"key":"10.1016\/j.heares.2014.03.005_bib21","first-page":"245","article-title":"Cochlear implant histopathology","volume":"12","author":"Linthicum","year":"1991","journal-title":"Am. J. Otol."},{"key":"10.1016\/j.heares.2014.03.005_bib22","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1097\/MLG.0b013e3181598887","article-title":"Outcomes of treatment of partial deafness with cochlear implantation: a DUET study","volume":"118","author":"Lorens","year":"2008","journal-title":"Laryngoscope"},{"key":"10.1016\/j.heares.2014.03.005_bib23","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.heares.2005.03.010","article-title":"Cochlear implantation in rats: a new surgical approach","volume":"205","author":"Lu","year":"2005","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2014.03.005_bib24","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1001\/archotol.1992.01880110125022","article-title":"Histopathology of the temporal bone following multichannel cochlear implantation","volume":"118","author":"Marsh","year":"1992","journal-title":"Arch. Otolaryngol. Head. Neck Surg."},{"key":"10.1016\/j.heares.2014.03.005_bib25","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/S0194-5998(97)70178-5","article-title":"Patterns of neural degeneration in the human cochlea and auditory nerve: implications for cochlear implantation","volume":"117","author":"Nadol","year":"1997","journal-title":"Otolaryngol. Head. Neck Surg."},{"key":"10.1016\/j.heares.2014.03.005_bib26","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1177\/000348940111000914","article-title":"Histopathology of cochlear implants in humans","volume":"110","author":"Nadol","year":"2001","journal-title":"Ann. Otol. Rhinol. Laryngol."},{"key":"10.1016\/j.heares.2014.03.005_bib27","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.3109\/00016480802629440","article-title":"An animal model of cochlear implantation with an intracochlear fluid delivery system","volume":"129","author":"Nguyen","year":"2009","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.heares.2014.03.005_bib28","series-title":"Assessment of Candidacy Cochlear Implant","first-page":"137","author":"Niparko","year":"2009"},{"key":"10.1016\/j.heares.2014.03.005_bib29","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.brainres.2006.03.017","article-title":"Contributions of mouse models to understanding of age- and noise-related hearing loss","volume":"1091","author":"Ohlemiller","year":"2006","journal-title":"Brain Res."},{"key":"10.1016\/j.heares.2014.03.005_bib30","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.heares.2011.05.002","article-title":"Cochlear infrastructure for electrical hearing","volume":"281","author":"Pfingst","year":"2011","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2014.03.005_bib31","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1097\/MAO.0b013e318281e0c9","article-title":"Hearing preservation surgery for cochlear implantation\u2013hearing and quality of life after 2 years","volume":"34","author":"Santa Maria","year":"2013","journal-title":"Otol. Neurotol."},{"key":"10.1016\/j.heares.2014.03.005_bib32","first-page":"606","article-title":"Cochlear implant-related osteoneogenesis in an animal model: fluorescent labeling","volume":"15","author":"Saunders","year":"1994","journal-title":"Am. J. Otol."},{"key":"10.1016\/j.heares.2014.03.005_bib33","first-page":"135","article-title":"Electric acoustic stimulation in children","volume":"67","author":"Skarzynski","year":"2010","journal-title":"Adv. Otorhinolaryngol."},{"key":"10.1016\/j.heares.2014.03.005_bib34","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1159\/000103208","article-title":"Quantitative evaluation of new bone and fibrous tissue in the cochlea following cochlear implantation in the human","volume":"12","author":"Somdas","year":"2007","journal-title":"Audiol. Neurootol."},{"key":"10.1016\/j.heares.2014.03.005_bib35","article-title":"Biomaterials in cochlear implants","volume":"8","author":"Stover","year":"2009","journal-title":"GMS. Curr. Top. Otorhinolaryngol. Head. Neck Surg."},{"key":"10.1016\/j.heares.2014.03.005_bib36","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1159\/000339894","article-title":"Hearing preservation after cochlear implantation using deeply inserted flex atraumatic electrode arrays","volume":"17","author":"Tamir","year":"2012","journal-title":"Audiol. Neurootol."},{"key":"10.1016\/j.heares.2014.03.005_bib37","first-page":"153","article-title":"Central physiological correlates of ageing and presbycusis in mice","volume":"476","author":"Willott","year":"1990","journal-title":"Acta Otolaryngol. Suppl."},{"key":"10.1016\/j.heares.2014.03.005_bib38","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0378-5955(03)00310-1","article-title":"Contribution of stapedial artery to blood flow in the cochlea and its surrounding bone","volume":"186","author":"Yamamoto","year":"2003","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2014.03.005_bib39","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1109\/RBME.2008.2008250","article-title":"Cochlear implants: system design, integration, and evaluation","volume":"1","author":"Zeng","year":"2008","journal-title":"IEEE Rev. Biomed. Eng."}],"container-title":["Hearing Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595514000379?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595514000379?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,5]],"date-time":"2018-10-05T18:57:18Z","timestamp":1538765838000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378595514000379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":40,"alternative-id":["S0378595514000379"],"URL":"https:\/\/doi.org\/10.1016\/j.heares.2014.03.005","relation":{},"ISSN":["0378-5955"],"issn-type":[{"value":"0378-5955","type":"print"}],"subject":[],"published":{"date-parts":[[2014,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cochlear implantation in the mouse via the round window: Effects of\u00a0array insertion","name":"articletitle","label":"Article Title"},{"value":"Hearing Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.heares.2014.03.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}