{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T02:11:53Z","timestamp":1791771113353,"version":"4.3.4"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["5R01DC011808"],"award-info":[{"award-number":["5R01DC011808"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000006","name":"Office of Naval Research","doi-asserted-by":"crossref","award":["N000141210731"],"award-info":[{"award-number":["N000141210731"]}],"id":[{"id":"10.13039\/100000006","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hearing Research"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1016\/j.heares.2014.08.004","type":"journal-article","created":{"date-parts":[[2014,9,9]],"date-time":"2014-09-09T08:45:58Z","timestamp":1410252358000},"page":"1-8","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"special_numbering":"C","title":["Prolonged noise exposure-induced auditory threshold shifts in rats"],"prefix":"10.1016","volume":"317","author":[{"given":"Guang-Di","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon","family":"Decker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8609-7816","authenticated-orcid":false,"given":"Vijaya Prakash","family":"Krishnan Muthaiah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Sheppard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Salvi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.heares.2014.08.004_bib1","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1121\/1.1911288","article-title":"Study of tinnitus induced temporarily by noise","volume":"44","author":"Atherley","year":"1968","journal-title":"J.\u00a0Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2014.08.004_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12070-011-0374-8","article-title":"Pathophysiology and treatment of tinnitus: an elusive disease","volume":"66","author":"Atik","year":"2014","journal-title":"Indian J. Otolaryngol. Head Neck Surg. Off. Publ. Assoc. Otolaryngol. India"},{"key":"10.1016\/j.heares.2014.08.004_bib3","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3109\/00016488709107322","article-title":"Acute acoustic trauma","volume":"104","author":"Axelsson","year":"1987","journal-title":"Acta otolaryngol."},{"key":"10.1016\/j.heares.2014.08.004_bib4","doi-asserted-by":"crossref","first-page":"271","DOI":"10.3109\/03005368509078983","article-title":"Tinnitus in noise-induced hearing loss","volume":"19","author":"Axelsson","year":"1985","journal-title":"Br. J. Audiol."},{"key":"10.1016\/j.heares.2014.08.004_bib5","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1121\/1.381767","article-title":"Asymptotic threshold shift in chinchillas exposed to impulse noise","volume":"63","author":"Blakeslee","year":"1978","journal-title":"J.\u00a0Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2014.08.004_bib6","series-title":"New Perspectives on Noise-induced Hearing Loss","first-page":"283","article-title":"Growth of hearing loss and cochlear lesion with increasing duration of noise exposure","author":"Bohne","year":"1982"},{"key":"10.1016\/j.heares.2014.08.004_bib7","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.heares.2014.02.003","article-title":"Manganese enhanced magnetic resonance imaging (MEMRI): a powerful new imaging method to study tinnitus","volume":"311C","author":"Cacace","year":"2014","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2014.08.004_bib8","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1177\/014556139707600413","article-title":"Protection against noise trauma by sound conditioning","volume":"76","author":"Canlon","year":"1997","journal-title":"Ear Nose Throat J."},{"key":"10.1016\/j.heares.2014.08.004_bib9","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1097\/00001756-199801260-00017","article-title":"Reducing noise damage by using a mid-frequency sound conditioning stimulus","volume":"9","author":"Canlon","year":"1998","journal-title":"Neuroreport"},{"key":"10.1016\/j.heares.2014.08.004_bib10","first-page":"23","article-title":"Noise-induced hearing loss in rats","volume":"3","author":"Cappaert","year":"2000","journal-title":"Noise Health"},{"key":"10.1016\/j.heares.2014.08.004_bib11","first-page":"1346","article-title":"Temporary threshold shifts produced by noise-exposure of long duration","volume":"75","author":"Carder","year":"1971","journal-title":"Trans. Am. Acad. Ophthalmol. Otolaryngol."},{"key":"10.1016\/j.heares.2014.08.004_bib12","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1044\/jshr.1503.603","article-title":"Temporary threshold shifts from prolonged exposure to noise","volume":"15","author":"Carder","year":"1972","journal-title":"J.\u00a0Speech Hear Res."},{"key":"10.1016\/j.heares.2014.08.004_bib13","doi-asserted-by":"crossref","first-page":"726","DOI":"10.7205\/MILMED.172.7.726","article-title":"Blast injury of the ear: clinical update from the global war on terror","volume":"172","author":"Cave","year":"2007","journal-title":"Mil. Med."},{"key":"10.1016\/j.heares.2014.08.004_bib14","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s10162-013-0375-2","article-title":"Behavioral evidence for possible simultaneous induction of hyperacusis and tinnitus following intense sound exposure","volume":"14","author":"Chen","year":"2013","journal-title":"J.\u00a0Assoc. Res. Otolaryngol. JARO"},{"key":"10.1016\/j.heares.2014.08.004_bib15","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/S0378-5955(02)00582-8","article-title":"Effect of hypoxia on noise-induced auditory impairment","volume":"172","author":"Chen","year":"2002","journal-title":"Hear Res."},{"key":"10.1016\/j.heares.2014.08.004_bib16","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0378-5955(02)00802-X","article-title":"The relationship between noise-induced hearing loss and hair cell loss in rats","volume":"177","author":"Chen","year":"2003","journal-title":"Hear Res."},{"key":"10.1016\/j.heares.2014.08.004_bib17","doi-asserted-by":"crossref","first-page":"658741","DOI":"10.1155\/2014\/658741","article-title":"Salicylate-induced auditory perceptual disorders and plastic changes in nonclassical auditory centers in rats","volume":"2014","author":"Chen","year":"2014","journal-title":"Neural Plast."},{"key":"10.1016\/j.heares.2014.08.004_bib18","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1121\/1.401309","article-title":"Recent studies of temporary threshold shift (TTS) and permanent threshold shift (PTS) in animals","volume":"90","author":"Clark","year":"1991","journal-title":"J.\u00a0Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2014.08.004_bib19","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1121\/1.386906","article-title":"Acoustic trauma: single neuron basis for the \u201chalf-octave shift\u201d","volume":"70","author":"Cody","year":"1981","journal-title":"J.\u00a0Acoust. Soc. Am."},{"issue":"2","key":"10.1016\/j.heares.2014.08.004_bib20","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.1111\/ejn.12580","article-title":"Neural changes accompanying tinnitus following unilateral acoustic trauma in the guinea pig","volume":"40","author":"Coomber","year":"2014","journal-title":"Eur. J. Neurosci."},{"issue":"Suppl.","key":"10.1016\/j.heares.2014.08.004_bib21","first-page":"1","article-title":"Temporary deafness following exposures to loud tones and noise","volume":"88","author":"Davis","year":"1950","journal-title":"Acta Otolaryngol. Stockh."},{"key":"10.1016\/j.heares.2014.08.004_bib22","doi-asserted-by":"crossref","first-page":"e44","DOI":"10.1097\/AUD.0000000000000010","article-title":"Hearing in middle age: a population snapshot of 40- to 69-year olds in the United Kingdom","volume":"35","author":"Dawes","year":"2014","journal-title":"Ear Hear."},{"key":"10.1016\/j.heares.2014.08.004_bib23","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0378-5955(98)00182-8","article-title":"Changes in distortion product otoacoustic emissions during prolonged noise exposure","volume":"127","author":"Eddins","year":"1999","journal-title":"Hear Res."},{"key":"10.1016\/j.heares.2014.08.004_bib24","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1121\/1.1531981","article-title":"Cochlear toughening, protection, and potentiation of noise-induced trauma by non-Gaussian noise","volume":"113","author":"Hamernik","year":"2003","journal-title":"J.\u00a0Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2014.08.004_bib25","doi-asserted-by":"crossref","first-page":"2356","DOI":"10.1523\/JNEUROSCI.3461-12.2013","article-title":"The auditory sensitivity is increased in tinnitus ears","volume":"33","author":"Hebert","year":"2013","journal-title":"J.\u00a0Neurosci. Off. J. Soc. Neurosci."},{"key":"10.1016\/j.heares.2014.08.004_bib26","doi-asserted-by":"crossref","first-page":"577","DOI":"10.3758\/s13428-011-0061-4","article-title":"A\u00a0two-choice sound localization procedure for detecting lateralized tinnitus in animals","volume":"43","author":"Heffner","year":"2011","journal-title":"Behav. Res. Methods"},{"key":"10.1016\/j.heares.2014.08.004_bib27","first-page":"33","article-title":"Considerations on assessing the risk of work-related hearing loss","volume":"3","author":"Henderson","year":"2001","journal-title":"Noise Health"},{"key":"10.1016\/j.heares.2014.08.004_bib28","first-page":"987","article-title":"Long-duration exposure to intermittent noises","volume":"47","author":"Johnson","year":"1976","journal-title":"Aviat. Space Environ. Med."},{"key":"10.1016\/j.heares.2014.08.004_bib29","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/S0378-5955(00)00138-6","article-title":"Plasticity of spontaneous neural activity in the dorsal cochlear nucleus after intense sound exposure","volume":"147","author":"Kaltenbach","year":"2000","journal-title":"Hear Res."},{"key":"10.1016\/j.heares.2014.08.004_bib30","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.heares.2006.07.007","article-title":"Course of hearing loss and occurrence of tinnitus","volume":"221","author":"Konig","year":"2006","journal-title":"Hear Res."},{"key":"10.1016\/j.heares.2014.08.004_bib31","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1121\/1.397957","article-title":"The growth of and recovery from TTS in human subjects exposed to impact noise","volume":"85","author":"Laroche","year":"1989","journal-title":"J.\u00a0Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2014.08.004_bib32","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1121\/1.1910600","article-title":"Relation of induced tinnitus to physical characteristics of the inducing stimuli","volume":"42","author":"Loeb","year":"1967","journal-title":"J.\u00a0Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2014.08.004_bib33","doi-asserted-by":"crossref","first-page":"4241","DOI":"10.1523\/JNEUROSCI.22-10-04241.2002","article-title":"Variation in inter-animal susceptibility to noise damage is associated with alpha 9 acetylcholine receptor subunit expression level","volume":"22","author":"Luebke","year":"2002","journal-title":"J.\u00a0Neurosci. Off. J. Soc. Neurosci."},{"key":"10.1016\/j.heares.2014.08.004_bib34","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.neuroscience.2014.03.020","article-title":"Therapeutic effect of sildenafil on blast-induced tinnitus and auditory impairment","volume":"269","author":"Mahmood","year":"2014","journal-title":"Neuroscience"},{"key":"10.1016\/j.heares.2014.08.004_bib35","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1590\/S2317-17822013000300006","article-title":"Genetic and audiologic study in elderly with sensorineural hearing loss","volume":"25","author":"Martins","year":"2013","journal-title":"CoDAS"},{"key":"10.1016\/j.heares.2014.08.004_bib36","series-title":"Human Asymptotic Threshold Shift. In Effects of Noise on Hearing","author":"Melnick","year":"1976"},{"key":"10.1016\/j.heares.2014.08.004_bib37","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1121\/1.401308","article-title":"Human temporary threshold shift (TTS) and damage risk","volume":"90","author":"Melnick","year":"1991","journal-title":"J.\u00a0Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2014.08.004_bib38","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0010-9452(73)80033-4","article-title":"Decruitment and the growth of loudness in the ears of brain-damaged adults","volume":"9","author":"Mencher","year":"1973","journal-title":"Cortex A J. Devoted Study Nerv. Syst. Behav."},{"key":"10.1016\/j.heares.2014.08.004_bib39","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1121\/1.386774","article-title":"Temporary threshold shifts produced by wideband noise","volume":"70","author":"Mills","year":"1981","journal-title":"J.\u00a0Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2014.08.004_bib40","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1121\/1.382791","article-title":"Temporary threshold shifts in humans exposed to octave bands of noise for 16 to 24 hours","volume":"65","author":"Mills","year":"1979","journal-title":"J.\u00a0Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2014.08.004_bib41","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1044\/jshr.1503.624","article-title":"Temporary threshold shifts produced by exposure to high-frequency noise","volume":"15","author":"Mills","year":"1972","journal-title":"J.\u00a0Speech Hear Res."},{"key":"10.1016\/j.heares.2014.08.004_bib42","series-title":"Effects of Noise on Hearing","year":"1976"},{"key":"10.1016\/j.heares.2014.08.004_bib43","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1080\/15459624.2011.609013","article-title":"Clinical characteristics of acoustic trauma caused by gunshot noise in mass rifle drills without ear protection","volume":"8","author":"Moon","year":"2011","journal-title":"J.\u00a0Occup. Environ. Hyg."},{"key":"10.1016\/j.heares.2014.08.004_bib44","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0378-5955(91)90041-7","article-title":"Frequency representation in the rat cochlea","volume":"51","author":"Muller","year":"1991","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2014.08.004_bib45","doi-asserted-by":"crossref","first-page":"297","DOI":"10.3109\/00206098409072841","article-title":"The effects of interruption on squirrel monkey temporary threshold shift to a 96-hour noise exposure","volume":"23","author":"Nielsen","year":"1984","journal-title":"Audiology"},{"key":"10.1016\/j.heares.2014.08.004_bib46","first-page":"96","article-title":"Protective mechanisms of sound conditioning","volume":"59","author":"Niu","year":"2002","journal-title":"Adv. Otorhinolaryngol."},{"key":"10.1016\/j.heares.2014.08.004_bib47","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1159\/000080226","article-title":"Protection against acoustic trauma by forward and backward sound conditioning","volume":"9","author":"Niu","year":"2004","journal-title":"Audiol. Neurootol."},{"key":"10.1016\/j.heares.2014.08.004_bib48","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1111\/j.1460-9568.2010.07542.x","article-title":"Rapid increases of gamma power in the auditory cortex following noise trauma in humans","volume":"33","author":"Ortmann","year":"2011","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.heares.2014.08.004_bib49","doi-asserted-by":"crossref","first-page":"e75011","DOI":"10.1371\/journal.pone.0075011","article-title":"Noise-induced tinnitus using individualized gap detection analysis and its relationship with hyperacusis, anxiety, and spatial cognition","volume":"8","author":"Pace","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.heares.2014.08.004_bib50","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1093\/occmed\/43.1.35","article-title":"Tinnitus in noise-exposed workers","volume":"43","author":"Phoon","year":"1993","journal-title":"Occup. Med. (Lond.)"},{"issue":"Suppl.","key":"10.1016\/j.heares.2014.08.004_bib51","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3109\/00016489709124081","article-title":"The \u201ctoughening\u201d phenomenon in rat's auditory organ","volume":"529","author":"Pukkila","year":"1997","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.heares.2014.08.004_bib52","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1121\/1.381298","article-title":"Threshold shift in the chinchilla from daily exposure to noise for six hours","volume":"61","author":"Saunders","year":"1977","journal-title":"J.\u00a0Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2014.08.004_bib53","first-page":"391","article-title":"Identification of the minimum noise level capable of producing an asymptotic temporary threshold shift","volume":"51","author":"Stephenson","year":"1980","journal-title":"Aviat. Space Environ. Med."},{"key":"10.1016\/j.heares.2014.08.004_bib54","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.jneumeth.2013.07.021","article-title":"A\u00a0novel behavioral assay for the assessment of acute tinnitus in rats optimized for simultaneous recording of oscillatory neural activity","volume":"219","author":"Stolzberg","year":"2013","journal-title":"J.\u00a0Neurosci. Methods"},{"key":"10.1016\/j.heares.2014.08.004_bib55","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0378-5955(92)90008-B","article-title":"The effect of 'conditioning' on hearing loss from a high frequency traumatic exposure","volume":"58","author":"Subramaniam","year":"1992","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2014.08.004_bib56","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.brainres.2012.02.008","article-title":"Noise exposure enhances auditory cortex responses related to hyperacusis behavior","volume":"1485","author":"Sun","year":"2012","journal-title":"Brain Res."},{"key":"10.1016\/j.heares.2014.08.004_bib57","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0378-5955(80)90047-7","article-title":"Hearing threshold shifts from prolonged exposure to noise in guinea pigs","volume":"3","author":"Syka","year":"1980","journal-title":"Hear Res."},{"key":"10.1016\/j.heares.2014.08.004_bib58","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.nbd.2006.09.004","article-title":"Sound conditioning protects hearing by activating the hypothalamic-pituitary-adrenal axis","volume":"25","author":"Tahera","year":"2007","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.heares.2014.08.004_bib59","first-page":"459","article-title":"Asymptotic threshold shift in people with sensorineural hearing loss","volume":"84","author":"Viall","year":"1977","journal-title":"Trans. Sect. Otolaryngol. Am. Acad. Ophthalmol. Otolaryngol."},{"key":"10.1016\/j.heares.2014.08.004_bib60","series-title":"Studies of Asymptotic TTS","author":"Ward","year":"1975"},{"key":"10.1016\/j.heares.2014.08.004_bib61","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0304-3940(98)00482-0","article-title":"Increases in spontaneous activity in the dorsal cochlear nucleus of the rat following exposure to high-intensity sound","volume":"250","author":"Zhang","year":"1998","journal-title":"Neurosci. Lett."}],"container-title":["Hearing Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595514001427?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595514001427?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,14]],"date-time":"2019-08-14T16:23:26Z","timestamp":1565799806000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378595514001427"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":61,"alternative-id":["S0378595514001427"],"URL":"https:\/\/doi.org\/10.1016\/j.heares.2014.08.004","relation":{},"ISSN":["0378-5955"],"issn-type":[{"value":"0378-5955","type":"print"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prolonged noise exposure-induced auditory threshold shifts in rats","name":"articletitle","label":"Article Title"},{"value":"Hearing Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.heares.2014.08.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}