{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:06:30Z","timestamp":1786989990069,"version":"build-2736575974"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"National Institutes on Deafness","award":["R01 DC003685"],"award-info":[{"award-number":["R01 DC003685"]}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["P30 DC005188"],"award-info":[{"award-number":["P30 DC005188"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hearing Research"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1016\/j.heares.2014.10.005","type":"journal-article","created":{"date-parts":[[2014,10,22]],"date-time":"2014-10-22T12:38:00Z","timestamp":1413981480000},"page":"18-22","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"special_numbering":"C","title":["Disparities in auditory physiology and pathology between C57BL\/6J and C57BL\/6N substrains"],"prefix":"10.1016","volume":"318","author":[{"given":"Ann","family":"Kendall","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochen","family":"Schacht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.heares.2014.10.005_bib1","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.heares.2013.01.006","article-title":"The mitochondrion: a perpetrator of acquired hearing loss","volume":"303","author":"B\u00f6ttger","year":"2013","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2014.10.005_bib2","doi-asserted-by":"crossref","first-page":"e61999","DOI":"10.1371\/journal.pone.0061999","article-title":"Mitochondrial peroxiredoxin 3 regulates sensory cell survival in the cochlea","volume":"8","author":"Chen","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.heares.2014.10.005_bib3","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0304-3835(80)90114-7","article-title":"Differential susceptibility of 3 sublines of C57BL\/6 mice to the induction of colorectal tumors by 1,2-dimethylhydrazine","volume":"9","author":"Diwan","year":"1980","journal-title":"Cancer Lett."},{"key":"10.1016\/j.heares.2014.10.005_bib4","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.2337\/db06-0358","article-title":"Deletion of nicotinamide nucleotide transhydrogenase: a new quantitive trait locus accounting for glucose intolerance in C57BL\/6J mice","volume":"55","author":"Freeman","year":"2006","journal-title":"Diabetes"},{"key":"10.1016\/j.heares.2014.10.005_bib5","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1016\/j.neurobiolaging.2009.09.009","article-title":"F1 (CBA\u00d7C57) mice show superior hearing in old age relative to their parental strains: hybrid vigor or a new animal model for \u201cgolden ears\u201d?","volume":"32","author":"Frisina","year":"2011","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.heares.2014.10.005_bib6","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1002\/dvdy.21048","article-title":"Reprogramming of genetic networks during initiation of the fetal alcohol syndrome","volume":"236","author":"Green","year":"2007","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.heares.2014.10.005_bib7","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1042\/bj0650546","article-title":"The distribution and properties of transhydrogenase from animal tissues","volume":"65","author":"Humphrey","year":"1957","journal-title":"Biochem. J."},{"key":"10.1016\/j.heares.2014.10.005_bib8","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.brainres.2006.01.066","article-title":"A\u00a0comparison of vestibular and auditory phenotypes in inbred mouse strains","volume":"1091","author":"Jones","year":"2006","journal-title":"Brain Res."},{"key":"10.1016\/j.heares.2014.10.005_bib9","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.heares.2011.11.007","article-title":"Genetic background effects on age-related hearing loss associated with Cdh23 variants in mice","volume":"283","author":"Kane","year":"2012","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2014.10.005_bib10","doi-asserted-by":"crossref","first-page":"827","DOI":"10.3109\/00016489109138418","article-title":"Age-related loss of auditory sensitivity in two mouse genotypes","volume":"111","author":"Li","year":"1991","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.heares.2014.10.005_bib11","doi-asserted-by":"crossref","first-page":"15611","DOI":"10.1074\/jbc.M113.533653","article-title":"Nicotinamide nucleotide transhydrogenase (Nnt) links the substrate requirement in brain mitochondria for hydrogen peroxide removal to the thioredoxin\/peroxiredoxin (Trx\/Prx) system","volume":"289","author":"Lopert","year":"2014","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.heares.2014.10.005_bib12","first-page":"29","article-title":"Behavioral profiles of three C57BL\/6 substrains","volume":"4","author":"Matsuo","year":"2010","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.heares.2014.10.005_bib13","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1038\/ng.2299","article-title":"Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial glucocorticoid deficiency","volume":"44","author":"Meimaridou","year":"2012","journal-title":"Nat. Genet."},{"key":"10.1016\/j.heares.2014.10.005_bib14","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1538\/expanim.58.141","article-title":"Genetic differences among C57BL\/6 substrains","volume":"58","author":"Mekada","year":"2009","journal-title":"Exp. Anim."},{"key":"10.1016\/j.heares.2014.10.005_bib15","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/ng1226","article-title":"Association of cadherin 23 with polygenic inheritance and genetic modification of sensorineural hearing loss","volume":"35","author":"Noben-Trauth","year":"2003","journal-title":"Nat. Genet."},{"key":"10.1016\/j.heares.2014.10.005_bib16","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.freeradbiomed.2013.05.049","article-title":"A\u00a0spontaneous mutation in the nicotinamide nucleotide transhydrogenase gene of C57BL\/6J mice results in mitochondrial redox abnormalities","volume":"63","author":"Ronchi","year":"2013","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.heares.2014.10.005_bib17","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.mcn.2007.09.006","article-title":"Math5 expression and function in the central auditory system","volume":"237","author":"Saul","year":"2008","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.heares.2014.10.005_bib18","doi-asserted-by":"crossref","first-page":"R82","DOI":"10.1186\/gb-2013-14-7-r82","article-title":"A\u00a0comparative phenotypic and genomic analysis of C57BL\/6J and C57BL\/6N mouse strains","volume":"14","author":"Simon","year":"2013","journal-title":"Genome Biol."},{"key":"10.1016\/j.heares.2014.10.005_bib19","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/nature10163","article-title":"A\u00a0conditional knockout resource for the genome-wide study of mouse gene function","volume":"474","author":"Skarnes","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.heares.2014.10.005_bib20","doi-asserted-by":"crossref","first-page":"e90279","DOI":"10.1371\/journal.pone.0090279","article-title":"Gene expression changes for antioxidants pathways in the mouse cochlea: relations to age-related hearing deficits","volume":"9","author":"Tadros","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.heares.2014.10.005_bib21","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1007\/s00125-005-1680-z","article-title":"A\u00a0genetic and physiological study of impaired glucose homeostasis control in C57BL\/6J mice","volume":"48","author":"Toye","year":"2005","journal-title":"Diabetologia"},{"key":"10.1016\/j.heares.2014.10.005_bib22","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0378-5955(01)00303-3","article-title":"Aminoglycoside ototoxicity in adult CBA, C57BL and BALB mice and the Sprague-Dawley rat","volume":"158","author":"Wu","year":"2001","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2014.10.005_bib23","doi-asserted-by":"crossref","first-page":"e62786","DOI":"10.1371\/journal.pone.0062786","article-title":"Identifying microRNAs involved in degeneration of the organ of corti during age-related hearing loss","volume":"8","author":"Zhang","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.heares.2014.10.005_bib24","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/S0378-5955(99)00003-9","article-title":"Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses","volume":"130","author":"Zheng","year":"1999","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2014.10.005_bib25","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/s11248-010-9403-8","article-title":"Genetic polymorphisms among C57BL\/6 mouse inbred strains","volume":"20","author":"Zurita","year":"2011","journal-title":"Transgenic Res."}],"container-title":["Hearing Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595514001695?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595514001695?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,28]],"date-time":"2018-09-28T05:54:04Z","timestamp":1538114044000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378595514001695"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12]]},"references-count":25,"alternative-id":["S0378595514001695"],"URL":"https:\/\/doi.org\/10.1016\/j.heares.2014.10.005","relation":{},"ISSN":["0378-5955"],"issn-type":[{"value":"0378-5955","type":"print"}],"subject":[],"published":{"date-parts":[[2014,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Disparities in auditory physiology and pathology between C57BL\/6J and C57BL\/6N substrains","name":"articletitle","label":"Article Title"},{"value":"Hearing Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.heares.2014.10.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}