{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T18:09:24Z","timestamp":1788545364725,"version":"build-2803163510"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,3,1]],"date-time":"2015-03-01T00:00:00Z","timestamp":1425168000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hearing Research"],"published-print":{"date-parts":[[2015,3]]},"DOI":"10.1016\/j.heares.2015.01.001","type":"journal-article","created":{"date-parts":[[2015,1,9]],"date-time":"2015-01-09T07:31:23Z","timestamp":1420788683000},"page":"12-24","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":53,"special_numbering":"C","title":["Recovery characteristics of the electrically stimulated auditory nerve in deafened guinea pigs: Relation to neuronal status"],"prefix":"10.1016","volume":"321","author":[{"given":"Dyan","family":"Ramekers","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huib","family":"Versnel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7770-6146","authenticated-orcid":false,"given":"Stefan B.","family":"Strahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sjaak F.L.","family":"Klis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilko","family":"Grolman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.heares.2015.01.001_bib1","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1097\/AUD.0b013e3181cb41aa","article-title":"Neural response telemetry Reconsidered: II. The influence of neural population on the ECAP recovery function and refractoriness","volume":"31","author":"Botros","year":"2010","journal-title":"Ear. Hear"},{"key":"10.1016\/j.heares.2015.01.001_bib2","doi-asserted-by":"crossref","first-page":"026023","DOI":"10.1088\/1741-2560\/9\/2\/026023","article-title":"Prediction and control of neural responses to pulsatile electrical stimulation","volume":"9","author":"Campbell","year":"2012","journal-title":"J.\u00a0Neural. Eng"},{"key":"10.1016\/j.heares.2015.01.001_bib3","doi-asserted-by":"crossref","first-page":"1250031","DOI":"10.1142\/S0129065712500311","article-title":"Efficacy of a new charge-balanced biphasic electrical stimulus in the isolated sciatic nerve and the hippocampal slice","volume":"23","author":"Cappaert","year":"2013","journal-title":"Int. J. Neural. Syst."},{"key":"10.1016\/j.heares.2015.01.001_bib4","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/978-1-4614-1590-9_40","article-title":"Relationships between auditory nerve activity and temporal pitch perception in cochlear implant users","volume":"787","author":"Carlyon","year":"2013","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.heares.2015.01.001_bib5","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.heares.2005.03.021","article-title":"Effect of inter-phase gap on the sensitivity of cochlear implant users to electrical stimulation","volume":"205","author":"Carlyon","year":"2005","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.01.001_bib6","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1002\/(SICI)1096-9861(19960101)364:1<6::AID-CNE2>3.0.CO;2-9","article-title":"Methods for determining numbers of cells and synapses: a case for more uniform standards of review","volume":"364","author":"Coggeshall","year":"1996","journal-title":"J.\u00a0Comp. Neurol."},{"key":"10.1016\/j.heares.2015.01.001_bib7","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1097\/01.mlg.0000227176.09500.28","article-title":"Multichannel cochlear implants: relation of histopathology to performance","volume":"116","author":"Fayad","year":"2006","journal-title":"Laryngoscope"},{"key":"10.1016\/j.heares.2015.01.001_bib8","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0378-5955(03)00261-2","article-title":"Auditory response to intracochlear electric stimuli following furosemide treatment","volume":"185","author":"Hu","year":"2003","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.01.001_bib9","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.heares.2012.01.010","article-title":"Temporal response properties of the auditory nerve: data from human cochlear-implant recipients","volume":"285","author":"Hughes","year":"2012","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.01.001_bib10","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/0378-5955(94)90154-6","article-title":"Adaptation in the compound action potential response of the guinea pig VIIIth nerve to electric stimulation","volume":"81","author":"Killian","year":"1994","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.01.001_bib11","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1097\/MAO.0b013e3181ec1d92","article-title":"The relationship between electrically evoked compound action potential and speech perception: a study in cochlear implant users with short electrode array","volume":"31","author":"Kim","year":"2010","journal-title":"Otol. Neurotol."},{"key":"10.1016\/j.heares.2015.01.001_bib12","doi-asserted-by":"crossref","first-page":"796","DOI":"10.3109\/00016489.2011.560187","article-title":"Recovery function of electrically evoked compound action potential in implanted children with auditory neuropathy: preliminary results","volume":"131","author":"Kim","year":"2011","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.heares.2015.01.001_bib13","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1085\/jgp.201311019","article-title":"Functional contributions of HCN channels in the primary auditory neurons of the mouse inner ear","volume":"142","author":"Kim","year":"2013","journal-title":"J.\u00a0Gen. Physiol."},{"key":"10.1016\/j.heares.2015.01.001_bib14","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1097\/AUD.0b013e318239adb8","article-title":"Relationships between electrically evoked potentials and loudness growth in bilateral cochlear implant users","volume":"33","author":"Kirby","year":"2012","journal-title":"Ear. Hear"},{"key":"10.1016\/j.heares.2015.01.001_bib15","doi-asserted-by":"crossref","first-page":"3751","DOI":"10.1152\/jn.00177.2005","article-title":"Ca2+-activated K+-current density is correlated with soma size in rat vestibular-afferent neurons in culture","volume":"94","author":"Lim\u00f3n","year":"2005","journal-title":"J.\u00a0Neurophysiol."},{"key":"10.1016\/j.heares.2015.01.001_bib16","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0378-5955(00)00172-6","article-title":"The neuronal response to electrical constant-amplitude pulse train stimulation: evoked compound action potential recordings","volume":"149","author":"Matsuoka","year":"2000","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.01.001_bib17","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0378-5955(00)00173-8","article-title":"The neuronal response to electrical constant-amplitude pulse train stimulation: additive Gaussian noise","volume":"149","author":"Matsuoka","year":"2000","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.01.001_bib18","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1097\/00004691-200401000-00006","article-title":"How does deep brain stimulation work? Present understanding and future questions","volume":"21","author":"McIntyre","year":"2004","journal-title":"J.\u00a0Clin. Neurophysiol."},{"key":"10.1016\/j.heares.2015.01.001_bib19","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0378-5955(93)90091-E","article-title":"Characterization of wave I of the electrically evoked auditory brainstem response in the guinea pig","volume":"69","author":"Miller","year":"1993","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.01.001_bib20","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1159\/000095966","article-title":"Measuring the refractoriness of the electrically stimulated auditory nerve","volume":"11","author":"Morsnowski","year":"2006","journal-title":"Audiol. Neurootol."},{"key":"10.1016\/j.heares.2015.01.001_bib21","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1121\/1.1371762","article-title":"Psychophysical recovery from single-pulse forward masking in electric hearing","volume":"109","author":"Nelson","year":"2001","journal-title":"J.\u00a0Acoust. Soc. Am."},{"key":"10.1016\/j.heares.2015.01.001_bib22","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.heares.2006.03.006","article-title":"Effect of interphase gap and pulse duration on electrically evoked potentials is correlated with auditory nerve survival","volume":"215","author":"Prado-Guitierrez","year":"2006","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.01.001_bib23","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/0378-5955(93)90034-X","article-title":"Recovery characteristics of auditory nerve fibres in the normal and noise-damaged guinea pig cochlea","volume":"71","author":"Prijs","year":"1993","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.01.001_bib24","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.heares.2012.03.002","article-title":"Neurotrophins and their role in the cochlea","volume":"288","author":"Ramekers","year":"2012","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.01.001_bib25","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s10162-013-0440-x","article-title":"Auditory-nerve responses to varied inter-phase gap and phase duration of the electric pulse stimulus as predictors for neuronal degeneration","volume":"15","author":"Ramekers","year":"2014","journal-title":"J.\u00a0Assoc. Res. Otolaryngol."},{"key":"10.1016\/j.heares.2015.01.001_bib26","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1097\/MAO.0000000000000443","article-title":"Within-subject comparison of word recognition and spiral ganglion cell count in bilateral cochlear implant recipients","volume":"35","author":"Seyyedi","year":"2014","journal-title":"Otol. Neurotol."},{"key":"10.1016\/j.heares.2015.01.001_bib27","doi-asserted-by":"crossref","first-page":"3131","DOI":"10.1111\/j.1460-9568.2004.03809.x","article-title":"Long-term sensorineural hearing loss induces functional changes in the rat auditory nerve","volume":"20","author":"Shepherd","year":"2004","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.heares.2015.01.001_bib28","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.heares.2011.04.019","article-title":"Nerve maintenance and regeneration in the damaged cochlea","volume":"281","author":"Shibata","year":"2011","journal-title":"Hear Res."},{"key":"10.1016\/j.heares.2015.01.001_bib29","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1111\/j.1460-9568.2007.05678.x","article-title":"Deafness alters auditory nerve fibre responses to cochlear implant stimulation","volume":"26","author":"Sly","year":"2007","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.heares.2015.01.001_bib30","doi-asserted-by":"crossref","first-page":"266","DOI":"10.3109\/00016487509124683","article-title":"Retrograde degeneration of the cochlear nerve","volume":"79","author":"Spoendlin","year":"1975","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.heares.2015.01.001_bib31","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.heares.2009.10.004","article-title":"Suppression of the acoustically evoked auditory-nerve response by electrical stimulation in the cochlea of the guinea pig","volume":"259","author":"Stronks","year":"2010","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.01.001_bib32","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0378-5955(84)90051-0","article-title":"Physiological properties of the electrically stimulated auditory nerve. I. Compound action potential recordings","volume":"14","author":"Stypulkowski","year":"1984","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.01.001_bib33","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.heares.2013.01.013","article-title":"Spiral ganglion cell morphology in guinea pigs after deafening and neurotrophic treatment","volume":"298","author":"van Loon","year":"2013","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.01.001_bib34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.heares.2007.03.003","article-title":"Time course of cochlear electrophysiology and morphology after combined administration of kanamycin and furosemide","volume":"231","author":"Versnel","year":"2007","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.01.001_bib35","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1097\/MAO.0b013e31828687b1","article-title":"The peripheral processes of spiral ganglion cells after intracochlear application of brain-derived neurotrophic factor in deafened guinea pigs","volume":"34","author":"Waaijer","year":"2013","journal-title":"Otol. Neurotol."},{"key":"10.1016\/j.heares.2015.01.001_bib36","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0006-8993(81)90028-7","article-title":"Spiral ganglion neuron loss following organ of Corti loss: a quantitative study","volume":"212","author":"Webster","year":"1981","journal-title":"Brain Res."},{"key":"10.1016\/j.heares.2015.01.001_bib37","first-page":"S30","article-title":"Temporal representations with cochlear implants","volume":"18","author":"Wilson","year":"1997","journal-title":"Am. J. Otol."},{"key":"10.1016\/j.heares.2015.01.001_bib38","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3109\/00016487409129730","article-title":"Degeneration of neural elements in the cochlea of the guinea pig after damage to the organ of corti by ototoxic antibiotics","volume":"326","author":"Ylikoski","year":"1974","journal-title":"Acta Otolaryngol. Suppl."},{"key":"10.1016\/j.heares.2015.01.001_bib39","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1007\/s10162-007-0086-7","article-title":"Changes across time in spike rate and spike amplitude of auditory nerve fibers stimulated by electric pulse trains","volume":"8","author":"Zhang","year":"2007","journal-title":"J.\u00a0Assoc. Res. Otolaryngol."}],"container-title":["Hearing Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595515000040?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595515000040?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T13:16:22Z","timestamp":1650978982000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378595515000040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3]]},"references-count":39,"alternative-id":["S0378595515000040"],"URL":"https:\/\/doi.org\/10.1016\/j.heares.2015.01.001","relation":{},"ISSN":["0378-5955"],"issn-type":[{"value":"0378-5955","type":"print"}],"subject":[],"published":{"date-parts":[[2015,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Recovery characteristics of the electrically stimulated auditory nerve in deafened guinea pigs: Relation to neuronal status","name":"articletitle","label":"Article Title"},{"value":"Hearing Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.heares.2015.01.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}