{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T19:48:46Z","timestamp":1790711326314,"version":"4.1.0"},"reference-count":75,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Hirschfield Foundation","award":["R01-DC010412"],"award-info":[{"award-number":["R01-DC010412"]}]},{"name":"R. Jamison and Betty Williams Professorship","award":["R01-DC009410"],"award-info":[{"award-number":["R01-DC009410"]}]},{"name":"NIH\/NIDCD","award":["P30-DC05188"],"award-info":[{"award-number":["P30-DC05188"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hearing Research"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1016\/j.heares.2015.07.018","type":"journal-article","created":{"date-parts":[[2015,7,29]],"date-time":"2015-07-29T23:40:29Z","timestamp":1438213229000},"page":"102-112","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Mice with conditional deletion of Cx26 exhibit no vestibular phenotype despite secondary loss of Cx30 in the vestibular end organs"],"prefix":"10.1016","volume":"328","author":[{"given":"Min Young","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoko","family":"Takada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohei","family":"Takada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle D.","family":"Kappy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa A.","family":"Beyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald L.","family":"Swiderski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley L.","family":"Godin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon","family":"Brewer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Michael","family":"King","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yehoash","family":"Raphael","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.heares.2015.07.018_bib1","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1515\/JBCPP.2000.11.3.181","article-title":"Auditory and vestibular mouse mutants: models for human deafness","volume":"11","author":"Ahituv","year":"2000","journal-title":"J.\u00a0Basic Clin. Physiol. Pharmacol."},{"key":"10.1016\/j.heares.2015.07.018_bib2","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1073\/pnas.0606855104","article-title":"Restoration of connexin26 protein level in the cochlea completely rescues hearing in a mouse model of human connexin30-linked deafness","volume":"104","author":"Ahmad","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.heares.2015.07.018_bib3","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.neuron.2012.05.019","article-title":"Restoration of hearing in the VGLUT3 knockout mouse using virally mediated gene therapy","volume":"75","author":"Akil","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.heares.2015.07.018_bib4","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.ijdevneu.2012.08.005","article-title":"The development of sensorimotor reflexes in albino mice; albino rats and black-hooded rats","volume":"30","author":"Allam","year":"2012","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.heares.2015.07.018_bib5","doi-asserted-by":"crossref","first-page":"895","DOI":"10.33549\/physiolres.931466","article-title":"Differential vulnerability of outer and inner hair cells during and after oxygen-glucose deprivation in organotypic cultures of newborn rats","volume":"58","author":"Amarjargal","year":"2009","journal-title":"Physiol. Res."},{"key":"10.1016\/j.heares.2015.07.018_bib6","doi-asserted-by":"crossref","first-page":"e4088","DOI":"10.1371\/journal.pone.0004088","article-title":"Gap junction mediated intercellular metabolite transfer in the cochlea is compromised in connexin30 null mice","volume":"3","author":"Chang","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.heares.2015.07.018_bib7","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.bbrc.2014.04.016","article-title":"Deafness induced by Connexin 26 (GJB2) deficiency is not determined by endocochlear potential (EP) reduction but is associated with cochlear developmental disorders","volume":"448","author":"Chen","year":"2014","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.heares.2015.07.018_bib8","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.bbrc.2014.01.154","article-title":"Down regulated connexin26 at different postnatal stage displayed different types of cellular degeneration and formation of organ of Corti","volume":"445","author":"Chen","year":"2014","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.heares.2015.07.018_bib9","doi-asserted-by":"crossref","first-page":"409","DOI":"10.3357\/ASEM.2903.2011","article-title":"Various anti-motion sickness drugs and core body temperature changes","volume":"82","author":"Cheung","year":"2011","journal-title":"Aviat. Space Environ. Med."},{"key":"10.1016\/j.heares.2015.07.018_bib10","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s00441-004-0861-2","article-title":"Expression of the connexin43- and connexin45-encoding genes in the developing and mature mouse inner ear","volume":"316","author":"Cohen-Salmon","year":"2004","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.heares.2015.07.018_bib11","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/S0960-9822(02)00904-1","article-title":"Targeted ablation of connexin26 in the inner ear epithelial gap junction network causes hearing impairment and cell death","volume":"12","author":"Cohen-Salmon","year":"2002","journal-title":"Curr. Biol."},{"key":"10.1016\/j.heares.2015.07.018_bib12","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1542\/peds.103.3.546","article-title":"Clinical studies of families with hearing loss attributable to mutations in the connexin 26 gene (GJB2\/DFNB1)","volume":"103","author":"Cohn","year":"1999","journal-title":"Pediatrics"},{"key":"10.1016\/j.heares.2015.07.018_bib13","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.neuroscience.2012.09.051","article-title":"Intercellular K(+) accumulation depolarizes type I vestibular hair cells and their associated afferent nerve calyx","volume":"227","author":"Contini","year":"2012","journal-title":"Neuroscience"},{"key":"10.1016\/j.heares.2015.07.018_bib14","first-page":"134","article-title":"Anxiety-related behavior and biogenic amine pathways in the rat following bilateral vestibular lesions","volume":"vol. 1164","author":"Darlington","year":"2009"},{"key":"10.1016\/j.heares.2015.07.018_bib15","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/S0140-6736(98)11071-1","article-title":"Clinical features of the prevalent form of childhood deafness, DFNB1, due to a connexin-26 gene defect: implications for genetic counselling","volume":"353","author":"Denoyelle","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.heares.2015.07.018_bib16","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1002\/ajmg.a.33828","article-title":"Vestibular dysfunction in DFNB1 deafness","volume":"155A","author":"Dodson","year":"2011","journal-title":"Am. J. Med. Genet. A"},{"key":"10.1016\/j.heares.2015.07.018_bib17","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1242\/jcs.02892","article-title":"Ablation of connexin43 in uterine smooth muscle cells of the mouse causes delayed parturition","volume":"119","author":"Doring","year":"2006","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.heares.2015.07.018_bib18","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1002\/glia.20315","article-title":"Expression pattern and functional characterization of connexin29 in transgenic mice","volume":"53","author":"Eiberger","year":"2006","journal-title":"Glia"},{"key":"10.1016\/j.heares.2015.07.018_bib19","first-page":"541","article-title":"Motion sickness decreases arterial pressure and therefore acceleration tolerance","volume":"76","author":"Eiken","year":"2005","journal-title":"Aviat. Space Environ. Med."},{"key":"10.1016\/j.heares.2015.07.018_bib20","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1097\/MOO.0b013e32834a9852","article-title":"Genetic disorders of the vestibular system","volume":"19","author":"Eppsteiner","year":"2011","journal-title":"Curr. Opin. Otolaryngol. Head Neck Surg."},{"key":"10.1016\/j.heares.2015.07.018_bib21","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1242\/jcs.125476","article-title":"Connexin30-mediated intercellular communication plays an essential role in epithelial repair in the cochlea","volume":"126","author":"Forge","year":"2013","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.heares.2015.07.018_bib22","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1080\/cac.10.4-6.341.346","article-title":"The inner ear contains heteromeric channels composed of cx26 and cx30 and deafness-related mutations in cx26 have a dominant negative effect on cx30","volume":"10","author":"Forge","year":"2003","journal-title":"Cell Commun. Adhes."},{"key":"10.1016\/j.heares.2015.07.018_bib23","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1159\/000058299","article-title":"Connexins and gap junctions in the inner ear","volume":"7","author":"Forge","year":"2002","journal-title":"Audiol. Neurootol."},{"key":"10.1016\/j.heares.2015.07.018_bib24","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1002\/cne.10916","article-title":"Gap junctions in the inner ear: comparison of distribution patterns in different vertebrates and assessment of connexin composition in mammals","volume":"467","author":"Forge","year":"2003","journal-title":"J.\u00a0Comp. Neurol."},{"key":"10.1016\/j.heares.2015.07.018_bib25","first-page":"134","article-title":"Gap junctions and connexin expression in the inner ear","volume":"219","author":"Forge","year":"1999","journal-title":"Novartis Found. Symp."},{"key":"10.1016\/j.heares.2015.07.018_bib26","series-title":"Head Stability during Natural Locomotion: Quantitative Peripheral Vestibular Assessment in Rodents","author":"Godin","year":"2015"},{"key":"10.1016\/j.heares.2015.07.018_bib27","first-page":"339","article-title":"Morphological aspects of potassium flow in the semicircular canal ampulla of the pigeon","volume":"20","author":"Helling","year":"2005","journal-title":"Histol. Histopathol."},{"key":"10.1016\/j.heares.2015.07.018_bib28","doi-asserted-by":"crossref","first-page":"9944","DOI":"10.1523\/JNEUROSCI.2990-06.2006","article-title":"Vestibular hair bundles control pH with (Na+, K+)\/H+ exchangers NHE6 and NHE9","volume":"26","author":"Hill","year":"2006","journal-title":"J.\u00a0Neurosci. Off. J. Soc. Neurosci."},{"key":"10.1016\/j.heares.2015.07.018_bib29","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1027\/\/0269-8803.16.3.150","article-title":"Facial skin pallor increases during motion sickness","volume":"16","author":"Holmes","year":"2002","journal-title":"J.\u00a0Psychophysiol."},{"key":"10.1016\/j.heares.2015.07.018_bib30","doi-asserted-by":"crossref","first-page":"395","DOI":"10.3109\/00016489509125280","article-title":"Vestibular modulation of the septo-hippocampal cholinergic system of rats","volume":"520","author":"Horii","year":"1995","journal-title":"Acta Oto-laryngol. Suppl."},{"key":"10.1016\/j.heares.2015.07.018_bib31","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.1152\/jn.00481.2014","article-title":"Utricular afferents: morphology of peripheral terminals","volume":"113","author":"Huwe","year":"2015","journal-title":"J.\u00a0Neurophysiol."},{"key":"10.1016\/j.heares.2015.07.018_bib32","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1007\/s00441-014-2029-z","article-title":"Connexins and gap junctions in the inner ear - it's not just about K recycling","volume":"360","author":"Jagger","year":"2015","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.heares.2015.07.018_bib33","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/s10162-010-0218-3","article-title":"The membrane properties of cochlear root cells are consistent with roles in potassium recirculation and spatial buffering","volume":"11","author":"Jagger","year":"2010","journal-title":"J.\u00a0Assoc. Res. Otolaryngol."},{"key":"10.1016\/j.heares.2015.07.018_bib34","doi-asserted-by":"crossref","first-page":"289","DOI":"10.3766\/jaaa.25.3.8","article-title":"Genetics of peripheral vestibular dysfunction: lessons from mutant mouse strains","volume":"25","author":"Jones","year":"2014","journal-title":"J.\u00a0Am. Acad. Audiol."},{"key":"10.1016\/j.heares.2015.07.018_bib35","doi-asserted-by":"crossref","first-page":"990","DOI":"10.3109\/00016481003596508","article-title":"Vestibular function of patients with profound deafness related to GJB2 mutation","volume":"130","author":"Kasai","year":"2010","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.heares.2015.07.018_bib36","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.neuroscience.2004.05.052","article-title":"Abnormal motor behavior and vestibular dysfunction in the stargazer mouse mutant","volume":"127","author":"Khan","year":"2004","journal-title":"Neuroscience"},{"key":"10.1016\/j.heares.2015.07.018_bib37","doi-asserted-by":"crossref","first-page":"4333","DOI":"10.1073\/pnas.97.8.4333","article-title":"KCNQ4, a K+ channel mutated in a form of dominant deafness, is expressed in the inner ear and the central auditory pathway","volume":"97","author":"Kharkovets","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.heares.2015.07.018_bib38","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1016\/j.febslet.2014.02.025","article-title":"Mix and match: investigating heteromeric and heterotypic gap junction channels in model systems and native tissues","volume":"588","author":"Koval","year":"2014","journal-title":"FEBS Lett."},{"key":"10.1016\/j.heares.2015.07.018_bib39","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1093\/hmg\/ddg116","article-title":"Transgenic expression of a dominant-negative connexin26 causes degeneration of the organ of Corti and non-syndromic deafness","volume":"12","author":"Kudo","year":"2003","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.heares.2015.07.018_bib40","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1055\/s-2001-19576","article-title":"Connexin26 and -30 in the Cochlea and their clinical relevance","volume":"80","author":"Lautermann","year":"2001","journal-title":"Laryngorhinootologie"},{"key":"10.1016\/j.heares.2015.07.018_bib41","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/s004410051192","article-title":"Expression of the gap-junction connexins 26 and 30 in the rat cochlea","volume":"294","author":"Lautermann","year":"1998","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.heares.2015.07.018_bib42","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s10162-006-0035-x","article-title":"Deletion of SLC19A2, the high affinity thiamine transporter, causes selective inner hair cell loss and an auditory neuropathy phenotype","volume":"7","author":"Liberman","year":"2006","journal-title":"J.\u00a0Assoc. Res. Otolaryngol."},{"key":"10.1016\/j.heares.2015.07.018_bib43","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1007\/s00221-011-2592-4","article-title":"Potassium accumulation between type I hair cells and calyx terminals in mouse crista","volume":"210","author":"Lim","year":"2011","journal-title":"Exp. Brain Res."},{"issue":"Suppl.\u00a01","key":"10.1016\/j.heares.2015.07.018_bib44","doi-asserted-by":"crossref","first-page":"S111","DOI":"10.1016\/S0925-4773(03)00102-3","article-title":"Expression profiles of the connexin genes, Gjb1 and Gjb3, in the developing mouse cochlea","volume":"119","author":"Lopez-Bigas","year":"2002","journal-title":"Mech. Dev."},{"key":"10.1016\/j.heares.2015.07.018_bib45","doi-asserted-by":"crossref","first-page":"C403","DOI":"10.1152\/ajpcell.00312.2001","article-title":"KCNJ10 (Kir4.1) potassium channel knockout abolishes endocochlear potential","volume":"282","author":"Marcus","year":"2002","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.heares.2015.07.018_bib46","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1002\/1097-0185(20010201)262:2<137::AID-AR1018>3.0.CO;2-2","article-title":"Connexin 26 distribution in gap junctions between melanocytes in the human vestibular dark cell area","volume":"262","author":"Masuda","year":"2001","journal-title":"Anat. Rec."},{"key":"10.1016\/j.heares.2015.07.018_bib47","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/nature03837","article-title":"Neural crest origins of the neck and shoulder","volume":"436","author":"Matsuoka","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.heares.2015.07.018_bib48","doi-asserted-by":"crossref","first-page":"17078","DOI":"10.1073\/pnas.252652299","article-title":"Evidence for vestibular regulation of autonomic functions in a mouse genetic model","volume":"99","author":"Murakami","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.heares.2015.07.018_bib49","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1002\/cne.1414","article-title":"Connexin26 in adult rodent central nervous system: demonstration at astrocytic gap junctions and colocalization with connexin30 and connexin43","volume":"441","author":"Nagy","year":"2001","journal-title":"J.\u00a0Comp. Neurol."},{"key":"10.1016\/j.heares.2015.07.018_bib50","doi-asserted-by":"crossref","first-page":"e1002966","DOI":"10.1371\/journal.pgen.1002966","article-title":"A\u00a0mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse","volume":"8","author":"Nakano","year":"2012","journal-title":"PLoS Genet."},{"key":"10.1016\/j.heares.2015.07.018_bib51","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.brainresbull.2010.04.004","article-title":"Histaminergic and cholinergic neuron systems in the impairment of human thermoregulation during motion sickness","volume":"82","author":"Nobel","year":"2010","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.heares.2015.07.018_bib52","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1007\/s00421-011-2142-6","article-title":"Effects of motion sickness on thermoregulatory responses in a thermoneutral air environment","volume":"112","author":"Nobel","year":"2012","journal-title":"Eur. J. Appl. Physiol."},{"key":"10.1016\/j.heares.2015.07.018_bib53","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-5955(98)00231-7","article-title":"The role of mouse mutants in the identification of human hereditary hearing loss genes","volume":"130","author":"Probst","year":"1999","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.07.018_bib54","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1002\/cne.21459","article-title":"Analysis of connexin subunits required for the survival of vestibular hair cells","volume":"504","author":"Qu","year":"2007","journal-title":"J.\u00a0Comp. Neurol."},{"key":"10.1016\/j.heares.2015.07.018_bib55","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1161\/01.RES.86.7.723","article-title":"Connexin expression and turnover: implications for cardiac excitability","volume":"86","author":"Saffitz","year":"2000","journal-title":"Circ. Res."},{"key":"10.1016\/j.heares.2015.07.018_bib56","doi-asserted-by":"crossref","first-page":"C63","DOI":"10.1152\/ajpcell.1988.254.1.C63","article-title":"Intercellular communication between ciliated cells in culture","volume":"254","author":"Sanderson","year":"1988","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.heares.2015.07.018_bib57","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S1525-1578(10)60522-3","article-title":"Hereditary non-syndromic sensorineural hearing loss: transforming silence to sound","volume":"6","author":"Schrijver","year":"2004","journal-title":"J.\u00a0Mol. Diagn."},{"key":"10.1016\/j.heares.2015.07.018_bib58","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.neuron.2007.11.032","article-title":"Sensorineural deafness and seizures in mice lacking vesicular glutamate transporter 3","volume":"57","author":"Seal","year":"2008","journal-title":"Neuron"},{"key":"10.1016\/j.heares.2015.07.018_bib59","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.brainres.2009.12.059","article-title":"Progressive vestibular mutation leads to elevated anxiety","volume":"1317","author":"Shefer","year":"2010","journal-title":"Brain Res."},{"key":"10.1016\/j.heares.2015.07.018_bib60","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1080\/00016480601002039","article-title":"Assessment of vestibular function of infants and children with congenital and acquired deafness using the ice-water caloric test, rotational chair test and vestibular-evoked myogenic potential recording","volume":"127","author":"Shinjo","year":"2007","journal-title":"Acta Otolaryngol."},{"key":"10.1016\/j.heares.2015.07.018_bib61","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0378-5955(01)00418-X","article-title":"The receptor potential in type I and type II vestibular system hair cells: a model analysis","volume":"165","author":"Soto","year":"2002","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.07.018_bib75","doi-asserted-by":"crossref","first-page":"3546","DOI":"10.1121\/1.418315","article-title":"Quantitative measures of hair cell loss in CBA and C57BL\/6 mice throughout their life spans","volume":"101","author":"Spongr","year":"1997","journal-title":"J. Acoust. Soc. Am"},{"key":"10.1016\/j.heares.2015.07.018_bib62","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0196-0709(79)80004-6","article-title":"Hearing thresholds with outer and inner hair cell loss","volume":"1","author":"Stebbins","year":"1979","journal-title":"Am. J. Otolaryngol."},{"key":"10.1016\/j.heares.2015.07.018_bib63","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1002\/cne.22117","article-title":"Connexin30 null and conditional connexin26 null mice display distinct pattern and time course of cellular degeneration in the cochlea","volume":"516","author":"Sun","year":"2009","journal-title":"J.\u00a0Comp. Neurol."},{"key":"10.1016\/j.heares.2015.07.018_bib64","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1177\/002215540305100705","article-title":"Expression of gap junction protein connexin43 in the adult rat cochlea: comparison with connexin26","volume":"51","author":"Suzuki","year":"2003","journal-title":"J.\u00a0Histochem. Cytochem."},{"key":"10.1016\/j.heares.2015.07.018_bib65","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.heares.2013.11.009","article-title":"Connexin 26 null mice exhibit spiral ganglion degeneration that can be blocked by BDNF gene therapy","volume":"309","author":"Takada","year":"2014","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.07.018_bib66","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1523\/JNEUROSCI.5055-05.2006","article-title":"Connexin29 is highly expressed in cochlear Schwann cells, and it is required for the normal development and function of the auditory nerve of mice","volume":"26","author":"Tang","year":"2006","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.heares.2015.07.018_bib67","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1097\/00001756-200508010-00009","article-title":"Vestibular dysfunction of patients with mutations of Connexin 26","volume":"16","author":"Todt","year":"2005","journal-title":"Neuroreport"},{"key":"10.1016\/j.heares.2015.07.018_bib68","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.neuroscience.2012.04.037","article-title":"Inwardly rectifying potassium channel Kir4.1 is localized at the calyx endings of vestibular afferents","volume":"215","author":"Udagawa","year":"2012","journal-title":"Neuroscience"},{"key":"10.1016\/j.heares.2015.07.018_bib69","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.heares.2013.05.003","article-title":"Tracing Sox10-expressing cells elucidates the dynamic development of the mouse inner ear","volume":"302","author":"Wakaoka","year":"2013","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.07.018_bib70","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1159\/000063736","article-title":"K(+) cycling and its regulation in the cochlea and the vestibular labyrinth","volume":"7","author":"Wangemann","year":"2002","journal-title":"Audiol. Neurootol."},{"key":"10.1016\/j.heares.2015.07.018_bib71","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1038\/3845","article-title":"Mutations in the gene encoding gap junction protein beta-3 associated with autosomal dominant hearing impairment","volume":"20","author":"Xia","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1016\/j.heares.2015.07.018_bib72","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.heares.2004.04.015","article-title":"Quantitative analysis of apoptotic and necrotic outer hair cells after exposure to different levels of continuous noise","volume":"196","author":"Yang","year":"2004","journal-title":"Hear. Res."},{"key":"10.1016\/j.heares.2015.07.018_bib73","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1097\/MAO.0b013e31815145e9","article-title":"Vestibular system in infants with hereditary nonsyndromic deafness","volume":"28","author":"Zagolski","year":"2007","journal-title":"Otol. Neurotol."},{"key":"10.1016\/j.heares.2015.07.018_bib74","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1152\/physiol.00018.2009","article-title":"Potassium ion movement in the inner ear: insights from genetic disease and mouse models","volume":"24","author":"Zdebik","year":"2009","journal-title":"Physiol. (Bethesda)"}],"container-title":["Hearing Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595515001586?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378595515001586?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T07:49:40Z","timestamp":1718005780000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378595515001586"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":75,"alternative-id":["S0378595515001586"],"URL":"https:\/\/doi.org\/10.1016\/j.heares.2015.07.018","relation":{},"ISSN":["0378-5955"],"issn-type":[{"value":"0378-5955","type":"print"}],"subject":[],"published":{"date-parts":[[2015,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mice with conditional deletion of Cx26 exhibit no vestibular phenotype despite secondary loss of Cx30 in the vestibular end organs","name":"articletitle","label":"Article Title"},{"value":"Hearing Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.heares.2015.07.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}