{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T20:21:42Z","timestamp":1776025302811,"version":"3.50.1"},"reference-count":39,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,2,21]],"date-time":"2020-02-21T00:00:00Z","timestamp":1582243200000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heliyon"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.heliyon.2020.e03479","type":"journal-article","created":{"date-parts":[[2020,2,25]],"date-time":"2020-02-25T08:30:31Z","timestamp":1582619431000},"page":"e03479","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Vitamin D nutritional status in the adult population in Colombia \u2013 An analytical cross-sectional study"],"prefix":"10.1016","volume":"6","author":[{"given":"Vargas-Uricoechea","family":"Hernando","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mera-Mami\u00e1n","family":"Andry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pinz\u00f3n-Fern\u00e1ndez","family":"Mar\u00eda Virginia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agredo","family":"Valentina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.heliyon.2020.e03479_bib1","doi-asserted-by":"crossref","first-page":"E676","DOI":"10.3390\/nu11030676","article-title":"Nutrigenomics of vitamin D","volume":"11","author":"Carlberg","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.heliyon.2020.e03479_bib2","first-page":"129","article-title":"Autocrine and paracrine actions of vitamin D","volume":"31","author":"Morris","year":"2010","journal-title":"Clin. Biochem. Rev."},{"key":"10.1016\/j.heliyon.2020.e03479_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000486060","article-title":"Physiology of the calcium-parathyroid hormone-vitamin D Axis","volume":"50","author":"Goltzman","year":"2018","journal-title":"Front. Horm. Res."},{"key":"10.1016\/j.heliyon.2020.e03479_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mce.2019.01.011","article-title":"Alternative binding sites at the vitamin D receptor and their ligands","volume":"485","author":"Mutchie","year":"2019","journal-title":"Mol. Cell. Endocrinol."},{"issue":"1","key":"10.1016\/j.heliyon.2020.e03479_bib5","doi-asserted-by":"crossref","first-page":"3","DOI":"10.11005\/jbm.2019.26.1.3","article-title":"The function of the vitamin D receptor and a possible role of enhancer RNA in epigenomic regulation of target genes: implications for bone metabolism","volume":"26","author":"Sawatsubashi","year":"2019","journal-title":"J.\u00a0Bone Metab."},{"key":"10.1016\/j.heliyon.2020.e03479_bib6","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.jsbmb.2019.02.001","article-title":"Vitamin D receptor: A critical regulator of inter-organ communication between skeletal and hematopoietic system","volume":"190","author":"Katayama","year":"2019","journal-title":"J. Steroid Biochem. Mol. Biol."},{"issue":"2","key":"10.1016\/j.heliyon.2020.e03479_bib7","first-page":"1145","article-title":"Vitamin D: current guidelines and future outlook","volume":"38","author":"Pilz","year":"2018","journal-title":"Anticancer Res."},{"issue":"3","key":"10.1016\/j.heliyon.2020.e03479_bib8","doi-asserted-by":"crossref","first-page":"E892","DOI":"10.3390\/ijms19030892","article-title":"Health risks of hypovitaminosis D: a review of new molecular insights","volume":"19","author":"Caccamo","year":"2018","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.heliyon.2020.e03479_bib9","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s00424-018-2231-z","article-title":"Physiological regulation of phosphate by vitamin D, parathyroid hormone (PTH) and phosphate (Pi)","volume":"471","author":"Jacquillet","year":"2019","journal-title":"Pfl\u00fcgers Archiv"},{"key":"10.1016\/j.heliyon.2020.e03479_bib10","doi-asserted-by":"crossref","first-page":"E436","DOI":"10.1210\/jc.2010-1886","article-title":"Relationship between vitamin D, parathyroid hormone, and bone health","volume":"96","author":"Sai","year":"2011","journal-title":"J.\u00a0Clin. Encocrinol. Metab."},{"key":"10.1016\/j.heliyon.2020.e03479_bib11","series-title":"Dietary Reference Intakes for Calcium and Vitamin D","first-page":"260","year":"2011"},{"issue":"7","key":"10.1016\/j.heliyon.2020.e03479_bib12","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1210\/jc.2011-0385","article-title":"Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline","volume":"96","author":"Holick","year":"2011","journal-title":"J.\u00a0Clin. Endocrinol. Metab."},{"issue":"5","key":"10.1016\/j.heliyon.2020.e03479_bib13","first-page":"301","article-title":"Vitamin D deficiency, its role in health and disease, and current supplementation recommendations","volume":"117","author":"Pfotenhauer","year":"2017","journal-title":"J.\u00a0Am. Osteopath. Assoc."},{"issue":"4","key":"10.1016\/j.heliyon.2020.e03479_bib14","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.ecl.2017.07.002","article-title":"Global overview of vitamin D status","volume":"46","author":"van Schoor","year":"2017","journal-title":"Endocrinol Metab. Clin. N. Am."},{"issue":"3","key":"10.1016\/j.heliyon.2020.e03479_bib15","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.tjem.2018.08.001","article-title":"User's guide to correlation coefficients","volume":"18","author":"Akoglu","year":"2018","journal-title":"Turk. J. Emerg. Med."},{"key":"10.1016\/j.heliyon.2020.e03479_bib17","first-page":"1","article-title":"When and how to diagnose and treat vitamin D deficiency in adults: a practical and clinical update","author":"Aoun","year":"2019","journal-title":"J.\u00a0Diet. Suppl."},{"key":"10.1016\/j.heliyon.2020.e03479_bib18","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1017\/S0007114513001840","article-title":"A\u00a0systematic review of vitamin D status in populations worldwide","volume":"111","author":"Hilger","year":"2014","journal-title":"Br. J. Nutr."},{"issue":"1","key":"10.1016\/j.heliyon.2020.e03479_bib19","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/nyas.13968","article-title":"Global prevalence and disease burden of vitamin D deficiency: a roadmap for action in low- and middle-income countries","volume":"1430","author":"Roth","year":"2018","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"6","key":"10.1016\/j.heliyon.2020.e03479_bib20","article-title":"Prevalence of vitamin D deficiency and associated risk factors in the US population (2011-2012)","volume":"10","author":"Parva","year":"2018","journal-title":"Cureus"},{"issue":"2","key":"10.1016\/j.heliyon.2020.e03479_bib21","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1136\/archdischild-2014-307214","article-title":"Sunshine and vitamin D","volume":"101","author":"Saraff","year":"2016","journal-title":"Arch. Dis. Child."},{"key":"10.1016\/j.heliyon.2020.e03479_bib23","series-title":"UPME\/IDEAM, Atlas de Radiaci\u00f3n Solar de Colombia","year":"2005"},{"issue":"4","key":"10.1016\/j.heliyon.2020.e03479_bib24","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.3945\/ajcn.115.120873","article-title":"Vitamin D deficiency in Europe: pandemic?","volume":"103","author":"Cashman","year":"2016","journal-title":"Am. J. Clin. Nutr."},{"issue":"10","key":"10.1016\/j.heliyon.2020.e03479_bib25","first-page":"4547","article-title":"Scientific opinion on dietary reference values for vitamin D","volume":"14","year":"2016","journal-title":"EFSA J"},{"key":"10.1016\/j.heliyon.2020.e03479_bib26","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1001\/archinternmed.2008.604","article-title":"Demographic differences and trends of vitamin D insufficiency in the US population, 1988-2004","volume":"169","author":"Ginde","year":"2009","journal-title":"Arch. Intern. Med."},{"issue":"3","key":"10.1016\/j.heliyon.2020.e03479_bib27","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1056\/NEJMra070553","article-title":"Vitamin D deficiency","volume":"357","author":"Holick","year":"2007","journal-title":"N.\u00a0Engl. J. Med."},{"issue":"5","key":"10.1016\/j.heliyon.2020.e03479_bib28","doi-asserted-by":"crossref","first-page":"4033","DOI":"10.1002\/jcp.26216","article-title":"Genetic and epigenetic factors influencing vitamin D status","volume":"233","author":"Bahrami","year":"2018","journal-title":"J.\u00a0Cell. Physiol."},{"issue":"2","key":"10.1016\/j.heliyon.2020.e03479_bib29","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s11154-017-9410-7","article-title":"Low vitamin D status and obesity: role of nutritionist","volume":"18","author":"Savastano","year":"2017","journal-title":"Rev. Endocr. Metab. Disord."},{"issue":"12","key":"10.1016\/j.heliyon.2020.e03479_bib30","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1016\/j.amjmed.2011.07.009","article-title":"The relationship between serum 25(OH)D and parathyroid hormone levels","volume":"124","author":"Saliba","year":"2011","journal-title":"Am. J. Med."},{"issue":"12","key":"10.1016\/j.heliyon.2020.e03479_bib31","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1016\/j.amjmed.2011.08.013","article-title":"The D-batable parathyroid hormone plateau","volume":"124","author":"Holick","year":"2011","journal-title":"Am. J. Med."},{"issue":"5","key":"10.1016\/j.heliyon.2020.e03479_bib32","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1007\/s00198-015-3475-5","article-title":"Establishment of a normal reference value of parathyroid hormone in a large healthy Chinese population and evaluation of its relation to bone turnover and bone mineral density","volume":"27","author":"Li","year":"2016","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.heliyon.2020.e03479_bib33","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.jsbmb.2017.01.021","article-title":"Vitamin D supplementation guidelines","volume":"175","author":"Pludowski","year":"2018","journal-title":"J.\u00a0Steroid Biochem. Mol. Biol."},{"issue":"2","key":"10.1016\/j.heliyon.2020.e03479_bib34","doi-asserted-by":"crossref","first-page":"R27","DOI":"10.1530\/EC-18-0432","article-title":"Vitamin D testing and treatment: a narrative review of current evidence","volume":"8","author":"Pilz","year":"2019","journal-title":"Endocr Connect"},{"issue":"1","key":"10.1016\/j.heliyon.2020.e03479_bib35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00774-016-0805-4","volume":"35","author":"Okazaki","year":"2017","journal-title":"J.\u00a0Bone Miner. Metabol."},{"issue":"2","key":"10.1016\/j.heliyon.2020.e03479_bib36","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1359\/jbmr.090728","article-title":"Bone mineralization defects and vitamin D deficiency: histomorphometric analysis of iliac crest bone biopsies and circulating 25-hydroxyvitamin D in 675 patients","volume":"25","author":"Priemel","year":"2010","journal-title":"J.\u00a0Bone Miner. Res."},{"key":"10.1016\/j.heliyon.2020.e03479_bib37","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1038\/bonekey.2014.6","article-title":"Vitamin D and bone health: epidemiologic studies","volume":"3","author":"Ebeling","year":"2014","journal-title":"BoneKEy Rep."},{"issue":"5","key":"10.1016\/j.heliyon.2020.e03479_bib38","doi-asserted-by":"crossref","first-page":"E546","DOI":"10.3390\/nu10050546","article-title":"AME and Italian AACE chapter. Italian association of clinical endocrinologists (AME) and Italian chapter of the American association of clinical endocrinologists (AACE) position statement: clinical Management of vitamin D deficiency in adults","volume":"10","author":"Cesareo","year":"2018","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.heliyon.2020.e03479_bib39","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1186\/s12889-018-5769-y","article-title":"Implications of standardization of serum 25-hydroxyvitamin D data for the evaluation of vitamin D status in Germany, including a temporal analysis","volume":"18","author":"Rabenberg","year":"2018","journal-title":"BMC Publ. Health"},{"key":"10.1016\/j.heliyon.2020.e03479_bib40","series-title":"Scientific Advisory Committee on Nutrition Vitamin D and Health","year":"2016"},{"issue":"2","key":"10.1016\/j.heliyon.2020.e03479_bib41","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S2213-8587(19)30007-5","article-title":"Research digest: vitamin D supplementation","volume":"7","author":"Preiss","year":"2019","journal-title":"Lancet Diabetes Endocrinol."}],"container-title":["Heliyon"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405844020303248?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405844020303248?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T08:26:21Z","timestamp":1763195181000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405844020303248"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["S2405844020303248"],"URL":"https:\/\/doi.org\/10.1016\/j.heliyon.2020.e03479","relation":{},"ISSN":["2405-8440"],"issn-type":[{"value":"2405-8440","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vitamin D nutritional status in the adult population in Colombia \u2013 An analytical cross-sectional study","name":"articletitle","label":"Article Title"},{"value":"Heliyon","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.heliyon.2020.e03479","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"e03479"}}