{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T16:07:01Z","timestamp":1790352421101,"version":"4.1.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,10,23]],"date-time":"2020-10-23T00:00:00Z","timestamp":1603411200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010447","name":"Kementerian Riset, Teknologi dan Pendidikan Tinggi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010447","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heliyon"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1016\/j.heliyon.2020.e05345","type":"journal-article","created":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T01:09:23Z","timestamp":1604538563000},"page":"e05345","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Optimal vaccination strategy for dengue transmission in Kupang city, Indonesia"],"prefix":"10.1016","volume":"6","author":[{"given":"Meksianis Z.","family":"Ndii","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ananda R.","family":"Mage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakobis J.","family":"Messakh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertha S.","family":"Djahi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.heliyon.2020.e05345_br0010","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1038\/nature12060","article-title":"The global distribution and burden of dengue","volume":"496","author":"Bhatt","year":"2013","journal-title":"Nature"},{"issue":"8","key":"10.1016\/j.heliyon.2020.e05345_br0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pntd.0004918","article-title":"Symptomatic dengue disease in five southeast Asian countries: Epidemiological evidence from a dengue vaccine trial","volume":"10","author":"Nealon","year":"2016","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"8","key":"10.1016\/j.heliyon.2020.e05345_br0030","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/S1473-3099(16)00146-8","article-title":"The global economic burden of dengue: a systematic analysis","volume":"16","author":"Shepard","year":"2016","journal-title":"Lancet Infect. Dis."},{"issue":"6","key":"10.1016\/j.heliyon.2020.e05345_br0040","doi-asserted-by":"crossref","first-page":"2793","DOI":"10.1128\/JCM.43.6.2793-2797.2005","article-title":"Discrimination between primary and secondary dengue virus infection by an immunoglobulin g avidity test using a single acute-phase serum sample","volume":"43","author":"Matheus","year":"2005","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.heliyon.2020.e05345_br0050","author":"World Health Organisation"},{"issue":"12","key":"10.1016\/j.heliyon.2020.e05345_br0060","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pntd.0005179","article-title":"The impact of the newly licensed dengue vaccine in endemic countries","volume":"10","author":"Aguiar","year":"2016","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"279","key":"10.1016\/j.heliyon.2020.e05345_br0070","doi-asserted-by":"crossref","first-page":"279ra37","DOI":"10.1126\/scitranslmed.3010370","article-title":"Modeling the impact on virus transmission of Wolbachia-mediated blocking of dengue virus infection of Aedes aegypti","volume":"7","author":"Ferguson","year":"2015","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.heliyon.2020.e05345_br0080","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.jtbi.2018.01.017","article-title":"Modelling the transmission dynamics of two-strain dengue in the presence awareness and vector control","volume":"443","author":"Zheng","year":"2018","journal-title":"J. Theor. Biol."},{"issue":"1","key":"10.1016\/j.heliyon.2020.e05345_br0090","article-title":"Rabies epidemic model with uncertainty in parameters: crisp and fuzzy approaches","volume":"332","author":"Ndii","year":"2018","journal-title":"IOP Conf. Ser., Mater. Sci. Eng."},{"key":"10.1016\/j.heliyon.2020.e05345_br0100","doi-asserted-by":"crossref","DOI":"10.1088\/1742-6596\/1490\/1\/012048","article-title":"Effects of vaccination on dengue transmission dynamics","volume":"1490","author":"Ndii","year":"2020","journal-title":"J. Phys. Conf. Ser."},{"key":"10.1016\/j.heliyon.2020.e05345_br0110","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.mbs.2018.09.007","article-title":"Optimal control strategies for dengue transmission in Pakistan","volume":"305","author":"Agusto","year":"2018","journal-title":"Math. Biosci."},{"key":"10.1016\/j.heliyon.2020.e05345_br0120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mbs.2013.10.006","article-title":"Vaccination models and optimal control strategies to dengue","volume":"247","author":"Rodrigues","year":"2014","journal-title":"Math. Biosci."},{"issue":"1","key":"10.1016\/j.heliyon.2020.e05345_br0130","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.mbs.2012.11.014","article-title":"An optimal control problem arising from a dengue disease transmission model","volume":"242","author":"Aldila","year":"2013","journal-title":"Math. Biosci."},{"issue":"mbe-16\u201303\u2013056","key":"10.1016\/j.heliyon.2020.e05345_br0140","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.3934\/mbe.2019056","article-title":"Optimal dengue vaccination strategies of seropositive individuals","volume":"16","author":"Shim","year":"2019","journal-title":"Math. Biosci. Eng."},{"issue":"1","key":"10.1016\/j.heliyon.2020.e05345_br0150","doi-asserted-by":"crossref","DOI":"10.1186\/s13662-019-2120-6","article-title":"Optimal control of the dengue dynamical transmission with vertical transmission","volume":"2019","author":"Pongsumpun","year":"2019","journal-title":"Adv. Differ. Equ."},{"key":"10.1016\/j.heliyon.2020.e05345_br0160","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.tpb.2016.05.003","article-title":"The effect of Wolbachia on dengue outbreaks when dengue is repeatedly introduced","volume":"111","author":"Ndii","year":"2016","journal-title":"Theor. Popul. Biol."},{"issue":"2","key":"10.1016\/j.heliyon.2020.e05345_br0180","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1056\/NEJMoa1411037","article-title":"Efficacy of a tetravalent dengue vaccine in children in Latin America","volume":"372","author":"Villar","year":"2015","journal-title":"N. Engl. J. Med."},{"issue":"13","key":"10.1016\/j.heliyon.2020.e05345_br0190","doi-asserted-by":"crossref","first-page":"2874","DOI":"10.1017\/S0950268816000753","article-title":"The effect of Wolbachia on dengue dynamics in the presence of two serotypes of dengue: symmetric and asymmetric epidemiological characteristics","volume":"144","author":"Ndii","year":"2016","journal-title":"Epidemiol. Infect."},{"issue":"8","key":"10.1016\/j.heliyon.2020.e05345_br0200","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1017\/S0950268809002040","article-title":"Assessing the effects of temperature on the population of aedes aegypti, the vector of dengue","volume":"137","author":"Yang","year":"2009","journal-title":"Epidemiol. Infect."},{"issue":"1","key":"10.1016\/j.heliyon.2020.e05345_br0210","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.jtbi.2008.04.011","article-title":"A methodology for performing global uncertainty and sensitivity analysis in systems biology","volume":"254","author":"Marino","year":"2008","journal-title":"J. Theor. Biol."},{"issue":"86","key":"10.1016\/j.heliyon.2020.e05345_br0220","doi-asserted-by":"crossref","DOI":"10.1098\/rsif.2012.1018","article-title":"Sensitivity analysis of infectious disease models: methods, advances and their application","volume":"10","author":"Wu","year":"2013","journal-title":"J. R. Soc. Interface"},{"issue":"4","key":"10.1016\/j.heliyon.2020.e05345_br0230","doi-asserted-by":"crossref","DOI":"10.1098\/rsos.181843","article-title":"Optimal control approaches for combining medicines and mosquito control in tackling dengue","volume":"7","author":"Rawson","year":"2020","journal-title":"R. Soc. Open Sci."},{"issue":"1","key":"10.1016\/j.heliyon.2020.e05345_br0240","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1186\/s13104-020-05043-z","article-title":"Optimal control strategy for the effects of hard water consumption on kidney-related diseases","volume":"13","author":"Ndii","year":"2020","journal-title":"BMC Res. Notes"},{"issue":"1","key":"10.1016\/j.heliyon.2020.e05345_br0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2019.e03030","article-title":"Optimal control of a discrete age-structured model for tuberculosis transmission","volume":"6","author":"Fatmawati","year":"2020","journal-title":"Heliyon"},{"issue":"2","key":"10.1016\/j.heliyon.2020.e05345_br0260","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1111\/sapm.12295","article-title":"Optimal control of dengue epidemic outbreaks under limited resources","volume":"144","author":"Sepulveda-Salcedo","year":"2020","journal-title":"Stud. Appl. Math."},{"key":"10.1016\/j.heliyon.2020.e05345_br0270","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.jtbi.2019.03.006","article-title":"Optimal control of acute myeloid leukaemia","volume":"470","author":"Sharp","year":"2019","journal-title":"J. Theor. Biol."},{"key":"10.1016\/j.heliyon.2020.e05345_br0280","doi-asserted-by":"crossref","DOI":"10.1201\/9781420011418","article-title":"Optimal Control Applied to Biological Models","author":"Lenhart","year":"2007"},{"issue":"2","key":"10.1016\/j.heliyon.2020.e05345_br0290","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.biosystems.2012.09.008","article-title":"Optimal control strategies and cost-effectiveness analysis of a malaria model","volume":"111","author":"Okosun","year":"2013","journal-title":"Biosystems"},{"issue":"1","key":"10.1016\/j.heliyon.2020.e05345_br0300","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1186\/s12936-018-2321-6","article-title":"Optimal control of malaria: combining vector interventions and drug therapies","volume":"17","author":"Khamis","year":"2018","journal-title":"Malar. J."},{"key":"10.1016\/j.heliyon.2020.e05345_br0310","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtbi.2020.110277","article-title":"Designing combination therapies using multiple optimal controls","volume":"497","author":"Sharp","year":"2020","journal-title":"J. Theor. Biol."},{"key":"10.1016\/j.heliyon.2020.e05345_br0320","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1603\/0022-2585-37.1.89","article-title":"Longitudinal studies of Aedes aegypti (Diptera: Culicidae) in Thailand and Puerto Rico: blood feeding frequency","volume":"37","author":"Scott","year":"2000","journal-title":"J. Med. Entomol."},{"key":"10.1016\/j.heliyon.2020.e05345_br0330","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1128\/CMR.11.3.480","article-title":"Dengue and dengue hemorrhagic fever","volume":"11","author":"Gubler","year":"1998","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.heliyon.2020.e05345_br0340","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.mbs.2006.11.011","article-title":"Estimation of the reproduction number of dengue fever from spatial epidemic data","volume":"208","author":"Chowel","year":"2007","journal-title":"Math. Biosci."},{"issue":"6","key":"10.1016\/j.heliyon.2020.e05345_br0350","doi-asserted-by":"crossref","first-page":"e0006616","DOI":"10.1371\/journal.pntd.0006616","article-title":"Dengue virus serotype distribution based on serological evidence in pediatric urban population in Indonesia","volume":"12","author":"Sasmono","year":"2018","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"3","key":"10.1016\/j.heliyon.2020.e05345_br0360","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.vaccine.2017.11.064","article-title":"Cost-effectiveness of dengue vaccination in ten endemic countries","volume":"36","author":"Zeng","year":"2018","journal-title":"Vaccine"},{"key":"10.1016\/j.heliyon.2020.e05345_br0370","series-title":"Indirect Health Care Costs","first-page":"63","author":"Boccuzzi","year":"2003"},{"key":"10.1016\/j.heliyon.2020.e05345_br0380","series-title":"Cost-Effectiveness in Health and Medicine","author":"Neumann","year":"2016"},{"issue":"6","key":"10.1016\/j.heliyon.2020.e05345_br0390","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1002\/mma.5491","article-title":"Effect of partial immunity on transmission dynamics of dengue disease with optimal control","volume":"42","author":"Jan","year":"2019","journal-title":"Math. Methods Appl. Sci."},{"issue":"18","key":"10.1016\/j.heliyon.2020.e05345_br0400","doi-asserted-by":"crossref","first-page":"5475","DOI":"10.1002\/mma.3932","article-title":"Optimal control approach to dengue reduction and prevention in Cali, Colombia","volume":"39","author":"Sepulveda","year":"2016","journal-title":"Math. Methods Appl. Sci."},{"key":"10.1016\/j.heliyon.2020.e05345_br0410","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.mbs.2014.12.011","article-title":"Modelling the transmission dynamics of dengue in the presence of Wolbachia","volume":"262","author":"Ndii","year":"2015","journal-title":"Math. Biosci."},{"key":"10.1016\/j.heliyon.2020.e05345_br0420","first-page":"62","article-title":"The effect of reinfection with the same serotype on dengue transmission dynamics","volume":"349","author":"Anggriani","year":"2019","journal-title":"Appl. Math. Comput."},{"issue":"2","key":"10.1016\/j.heliyon.2020.e05345_br0430","doi-asserted-by":"crossref","first-page":"78","DOI":"10.3390\/tropicalmed5020078","article-title":"Modelling the use of Vaccine and Wolbachia on dengue transmission dynamics","volume":"5","author":"Ndii","year":"2020","journal-title":"Trop. Med. Infect. Dis."}],"container-title":["Heliyon"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405844020321885?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405844020321885?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T15:39:24Z","timestamp":1790350764000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405844020321885"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":42,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["S2405844020321885"],"URL":"https:\/\/doi.org\/10.1016\/j.heliyon.2020.e05345","relation":{},"ISSN":["2405-8440"],"issn-type":[{"value":"2405-8440","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Optimal vaccination strategy for dengue transmission in Kupang city, Indonesia","name":"articletitle","label":"Article Title"},{"value":"Heliyon","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.heliyon.2020.e05345","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"e05345"}}