{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T05:27:18Z","timestamp":1793597238766,"version":"4.5.0"},"reference-count":80,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,17]],"date-time":"2022-08-17T00:00:00Z","timestamp":1660694400000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heliyon"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.heliyon.2022.e10366","type":"journal-article","created":{"date-parts":[[2022,8,23]],"date-time":"2022-08-23T09:51:25Z","timestamp":1661248285000},"page":"e10366","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Bridelia ferruginea Benth.; An ethnomedicinal, phytochemical, pharmacological and toxicological review"],"prefix":"10.1016","volume":"8","author":[{"given":"Genevieve Naana","family":"Yeboah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederick William Akuffo","family":"Owusu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary-Ann","family":"Archer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael Odoi","family":"Kyene","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doris","family":"Kumadoh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederick","family":"Ayertey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana Oteng","family":"Mintah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3702-2567","authenticated-orcid":false,"given":"Peter","family":"Atta-Adjei Junior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfred Ampomah","family":"Appiah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.heliyon.2022.e10366_bib1","doi-asserted-by":"crossref","first-page":"137","DOI":"10.4314\/bajopas.v10i1.28S","article-title":"Effects of column fractions on the leaves extract of Bridelia ferruginea on bacteria","volume":"10","author":"Abubakar","year":"2018","journal-title":"Bayero J. Pure and Appl. Sci."},{"issue":"3","key":"10.1016\/j.heliyon.2022.e10366_bib2","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.jep.2007.01.011","article-title":"The perception and practice of traditional medicine in the treatment of cancers and inflammations by the Hausa and Fulani tribes of Northern Nigeria","volume":"111","author":"Abubakar","year":"2007","journal-title":"J.\u00a0Ethnopharmacol."},{"key":"10.1016\/j.heliyon.2022.e10366_bib3","series-title":"Towards a Rational Scientific Basis for Herbal Medicine","author":"Addae-Mensah","year":"1992"},{"issue":"8","key":"10.1016\/j.heliyon.2022.e10366_bib4","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1016\/S0031-9422(00)82558-3","article-title":"Terpenoids and flavonoids of Bridelia ferruginea","volume":"24","author":"Addae-Mensah","year":"1985","journal-title":"Phytochemistry"},{"issue":"4","key":"10.1016\/j.heliyon.2022.e10366_bib5","first-page":"650","article-title":"Phytochemical and antimicrobial screening of the crude extracts from the root, stem bark and leaves of Bridelia ferruginea","volume":"8","author":"Adebayo","year":"2009","journal-title":"Afr. J. Biotechnol."},{"issue":"6","key":"10.1016\/j.heliyon.2022.e10366_bib6","first-page":"1","article-title":"Evaluation of anthelmintic potential of aqueous extract of the stem bark of Bridelia ferruginea (benth) euphorbiaceae","volume":"24","author":"Adebayo","year":"2018","journal-title":"J.\u00a0Pharmaceut. Res. Int."},{"issue":"1","key":"10.1016\/j.heliyon.2022.e10366_bib7","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.jep.2010.09.011","article-title":"Antibacterial, antioxidant and fibroblast growth stimulation activity of crude extracts of Bridelia ferruginea leaf, a wound-healing plant of Nigeria","volume":"133","author":"Adetutu","year":"2011","journal-title":"J.\u00a0Ethnopharmacol."},{"issue":"3","key":"10.1016\/j.heliyon.2022.e10366_bib8","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.joim.2018.04.006","article-title":"Inhibitory potentials of phenolic-rich extracts from Bridelia ferruginea on two key carbohydrate-metabolizing enzymes and Fe2+-induced pancreatic oxidative stress","volume":"16","author":"Afolabi","year":"2018","journal-title":"J.\u00a0Integr. Med."},{"issue":"2","key":"10.1016\/j.heliyon.2022.e10366_bib9","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1080\/14786419.2018.1440225","article-title":"Chemical and biological studies on Bridelia ferruginea grown in Nigeria","volume":"33","author":"Afolayan","year":"2019","journal-title":"Nat. Prod. Res."},{"issue":"3","key":"10.1016\/j.heliyon.2022.e10366_bib10","doi-asserted-by":"crossref","first-page":"248","DOI":"10.9734\/IJBCRR\/2013\/3859","article-title":"Evaluation of anti-diabetic and liver enzymes activity of aqueous extracts of moringa oleifera and Bridelia ferruginea leaves in alloxan induced diabetic albino rats","volume":"3","author":"Aja","year":"2013","journal-title":"Int. J. Biochem. Res. Rev."},{"issue":"1","key":"10.1016\/j.heliyon.2022.e10366_bib11","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0367-326X(99)00113-6","article-title":"Antimicrobial activity of Bridelia ferruginea fruit","volume":"71","author":"Akinpelu","year":"2000","journal-title":"Fitoterapia"},{"issue":"3","key":"10.1016\/j.heliyon.2022.e10366_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.9734\/JAMPS\/2017\/34172","article-title":"The phytochemical and antimicrobial potentials of the crude extracts of Bridelia ferruginea and the extracellular biosynthesized silver nanoparticles","volume":"14","author":"Akinsete","year":"2017","journal-title":"JAMPS"},{"issue":"3","key":"10.1016\/j.heliyon.2022.e10366_bib13","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/0378-8741(82)90056-3","article-title":"Clinical evaluation of a traditional herbal practice in Nigeria: a preliminary report","volume":"6","author":"Akubue","year":"1982","journal-title":"J.\u00a0Ethnopharmacol."},{"issue":"22","key":"10.1016\/j.heliyon.2022.e10366_bib14","first-page":"5366","article-title":"Pharmacological profile of aqueous extract of Bridelia ferruginea stem bark in the relief of pain and fever","volume":"5","author":"Akuodor","year":"2011","journal-title":"J.\u00a0Med. Plants Res."},{"issue":"4","key":"10.1016\/j.heliyon.2022.e10366_bib15","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1007\/s00436-019-06262-5","article-title":"In vitro anthelmintic effects of Bridelia ferruginea , Combretum glutinosum , and Mitragyna inermis leaf extracts on Haemonchus contortus , an abomasal nematode of small ruminants","volume":"118","author":"Alowanou","year":"2019","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.heliyon.2022.e10366_bib16","series-title":"African Medicinal Plants","first-page":"67","article-title":"The Practice of Phytotherapy in Ghana","author":"Ampofo","year":"1979"},{"issue":"2","key":"10.1016\/j.heliyon.2022.e10366_bib17","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1515\/intox-2015-0014","article-title":"Toxicological evaluation of the aqueous stem bark extract of Bridelia ferruginea (Euphorbiaceae) in rodents","volume":"8","author":"Awodele","year":"2015","journal-title":"Interdiscipl. Toxicol."},{"key":"10.1016\/j.heliyon.2022.e10366_bib18","series-title":"Medicinal Plants of West Africa","first-page":"162","author":"Ayensu","year":"1978"},{"issue":"1","key":"10.1016\/j.heliyon.2022.e10366_bib19","first-page":"1","article-title":"Facilitators and barriers of herbal medicine use in Accra, Ghana: an inductive exploratory study","volume":"16","author":"Aziato","year":"2016","journal-title":"BMC Compl. Alternative Med."},{"issue":"10","key":"10.1016\/j.heliyon.2022.e10366_bib20","doi-asserted-by":"crossref","first-page":"182","DOI":"10.5897\/JPP2018.0528","article-title":"Catechins as antidiabetic compounds of Bridelia ferruginea Benth root bark extract","volume":"10","author":"Bakoma","year":"2018","journal-title":"J.\u00a0Pharmacogn. Phytotherapy"},{"key":"10.1016\/j.heliyon.2022.e10366_bib21","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.fct.2012.11.021","article-title":"Acute and sub-chronic (28 days) oral toxicity evaluation of hydroethanolic extract of Bridelia ferruginea Benth root bark in male rodent animals","volume":"52","author":"Bakoma","year":"2013","journal-title":"Food Chem. Toxicol."},{"issue":"2","key":"10.1016\/j.heliyon.2022.e10366_bib22","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S1262-3636(07)70265-3","article-title":"Herbal medicine and treatment of diabetes in Africa : an example from Guinea","volume":"32","author":"Bald\u00e9","year":"2006","journal-title":"Diabetes Metabol."},{"key":"10.1016\/j.heliyon.2022.e10366_bib23","first-page":"1","article-title":"Review of the phytochemical, pharmacological and toxicological properties of Alstonia scholaris Linn. R. Br (Saptaparna)","author":"Baliga","year":"2012","journal-title":"Chin. J. Integr. Med."},{"issue":"12","key":"10.1016\/j.heliyon.2022.e10366_bib24","first-page":"31","article-title":"\u03b1 -Glucosidase inhibition , antioxidant and cytotoxicity activities of semi- ethanolic extracts of Bridellia ferruginea benth . and Ceiba pentandra L. Gaerth from Benin","volume":"2","author":"Bothon","year":"2012","journal-title":"Res. J. Chem. Sci."},{"key":"10.1016\/j.heliyon.2022.e10366_bib25","series-title":"Ghana Herbal Pharmacopoeia","author":"Boye","year":"1992"},{"issue":"1","key":"10.1016\/j.heliyon.2022.e10366_bib26","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1080\/10575639708043756","article-title":"Gallocatechin\u2013(4\u2032\u2192 0\u2192 7)-epigallocatechin, a new biflavonoid isolated from Bridelia Ferruginea","volume":"11","author":"Bruyne","year":"1997","journal-title":"Nat. Prod. Lett."},{"key":"10.1016\/j.heliyon.2022.e10366_bib27","volume":"2","author":"Burkill","year":"1994"},{"issue":"5","key":"10.1016\/j.heliyon.2022.e10366_bib28","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1211\/0022357011775893","article-title":"Radical scavenging and xanthine oxidase inhibitory activity of phenolic compounds from Bridelia ferruginea stem bark","volume":"53","author":"Cimanga","year":"2001","journal-title":"J.\u00a0Pharm. Pharmacol."},{"issue":"3","key":"10.1016\/j.heliyon.2022.e10366_bib29","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1055\/s-1999-14059","article-title":"Complement-inhibiting constituents of Bridelia ferruginea stem bark","volume":"65","author":"Cimanga","year":"1999","journal-title":"Planta Med."},{"issue":"4","key":"10.1016\/j.heliyon.2022.e10366_bib30","first-page":"43","article-title":"In vitro evidence of anti-infective activity of crude aqueous extract obtained by boiling ripe stem-bark of Bridelia ferruginea Benth","volume":"2","author":"Dada-Adegbola","year":"2010","journal-title":"J.\u00a0Pharmacogn. Phytotherapy"},{"issue":"5","key":"10.1016\/j.heliyon.2022.e10366_bib31","doi-asserted-by":"crossref","first-page":"10","DOI":"10.9734\/jamps\/2020\/v22i530170","article-title":"In-vivo anti-typhoid activities of ethanol stem bark extract of Bridelia ferruginea (wild) in albino rats infected with Salmonella typhi","volume":"22","author":"Dada","year":"2020","journal-title":"J.\u00a0Adv. Med. Pharmaceut. Sci."},{"issue":"5","key":"10.1016\/j.heliyon.2022.e10366_bib33","doi-asserted-by":"crossref","first-page":"191","DOI":"10.3923\/jas.2020.191.195","article-title":"Sub-chronic (28-days) toxicity study of hydroalcohol stem bark extract of Bridelia ferruginea (euphorbiaceae) on wistar rat","volume":"20","author":"D\u00e9l","year":"2020","journal-title":"J.\u00a0Appl. Sci."},{"issue":"6","key":"10.1016\/j.heliyon.2022.e10366_bib34","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1038\/sj.ejcn.1601916","article-title":"Absorption of kaempferol from endive, a source of kaempferol-3-glucuronide, in humans","volume":"58","author":"DuPont","year":"2004","journal-title":"Eur. J. Clin. Nutr."},{"issue":"2","key":"10.1016\/j.heliyon.2022.e10366_bib35","first-page":"45","article-title":"Trypanocidal potential of methanolic extract of Bridelia ferruginea benth bark in Rattus novergicus","volume":"2","author":"Ekanem","year":"2008","journal-title":"Afr. J. Biochem. Res."},{"issue":"1","key":"10.1016\/j.heliyon.2022.e10366_bib36","first-page":"1","article-title":"Studies on the antiulcer and gastrointestinal effects of stem bark extract of Bridelia ferruginea","volume":"8","author":"Ezike","year":"2011","journal-title":"J.\u00a0Compl. Integr. Med."},{"issue":"2","key":"10.1016\/j.heliyon.2022.e10366_bib37","doi-asserted-by":"crossref","first-page":"S981","DOI":"10.1016\/S2221-1691(12)60347-5","article-title":"Antioxidant and cytotoxicity of Bridelia ferruginea leaves acetate fraction from","volume":"2","author":"Fabiyi","year":"2012","journal-title":"Asian Pac. J. Trop. Biomed."},{"key":"10.1016\/j.heliyon.2022.e10366_bib38","series-title":"Ethnomedicinal Uses of Plants in Nigeria","first-page":"276","author":"Gill","year":"1992"},{"issue":"8878","key":"10.1016\/j.heliyon.2022.e10366_bib39","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/0140-6736(93)92876-U","article-title":"Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study","volume":"342","author":"Hertog","year":"1993","journal-title":"Lancet"},{"issue":"11","key":"10.1016\/j.heliyon.2022.e10366_bib40","doi-asserted-by":"crossref","first-page":"22","DOI":"10.22192\/ijcrcps.2017.04.11.005","article-title":"Comparative study of Antihyperglycemic activity of aqueous extracts from the leaves of Bridelia ferruginea, Lophira lanceolata and Oxytenanthera abyssinica, with their mixture","volume":"4","author":"Houndjo","year":"2017","journal-title":"Int. J. Curr. Res. Chem. Pharmaceut. Sci."},{"issue":"4","key":"10.1016\/j.heliyon.2022.e10366_bib41","first-page":"397","article-title":"Phytochemistryand acute toxicity study of Bridelia ferruginea extracts","volume":"12","author":"Ikechukwu","year":"2015","journal-title":"World J. Med. Sci."},{"issue":"3","key":"10.1016\/j.heliyon.2022.e10366_bib42","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0378-8741(94)90041-8","article-title":"Antimicrobial activity of bark extracts of Bridelia ferruginea (Euphorbiaceae)","volume":"43","author":"Irobi","year":"1994","journal-title":"J.\u00a0Ethnopharmacol."},{"issue":"8","key":"10.1016\/j.heliyon.2022.e10366_bib43","first-page":"8","article-title":"The Effect of Bridelia ferruginea Bark extracts on some pathogenic micro-organisms","volume":"2009","author":"Jose","year":"2009","journal-title":"Ethnobotanical Leaflets"},{"issue":"3","key":"10.1016\/j.heliyon.2022.e10366_bib44","doi-asserted-by":"crossref","first-page":"416","DOI":"10.5251\/abjna.2010.1.3.416.420","article-title":"In vitro antimicrobial properties of Bridelia ferruginea on some clinical isolates","volume":"1","author":"Kareem","year":"2010","journal-title":"Agric. Biol. J. N. Am."},{"key":"10.1016\/j.heliyon.2022.e10366_bib45","first-page":"209","article-title":"The effect of Bridellia ferruginea and Senna alata on plasma glucose concentration in normoglycemic and glucose induced hyperglycemic rats","volume":"10","author":"Kolawole","year":"2006","journal-title":"Ethnobotanical Leaflets"},{"key":"10.1016\/j.heliyon.2022.e10366_bib46","first-page":"1387","article-title":"Studies on the efficacy of Bridelia ferruginea benth extract for water purification","volume":"18","author":"Kolawole","year":"2003","journal-title":"Niger. J. Pure Appl. Sci"},{"issue":"3","key":"10.1016\/j.heliyon.2022.e10366_bib47","first-page":"82","article-title":"Toxicological renal effects of Bridelia ferruginea-treated wastewater in rats","volume":"3","author":"Kolawole","year":"2009","journal-title":"Afr. J. Microbiol. Res."},{"issue":"7","key":"10.1016\/j.heliyon.2022.e10366_bib48","first-page":"2130","article-title":"Phytochemical study and antibacterial, antifungal and antioxidant properties of Bridelia ferruginea and Pteleopsis suberosa","volume":"3","author":"Lagnika","year":"2012","journal-title":"Int. J. Pharmaceut. Sci. Res."},{"key":"10.1016\/j.heliyon.2022.e10366_bib49","series-title":"Repellent Effect and Insecticidal Activities of Bridelia Ferruginea , Blighia Sapida , and Khaya Senegalensis Leaves Powders and Extracts against Dinoderus Porcellus in Infested Dried Yam Chips","author":"Loko","year":"2017"},{"issue":"6","key":"10.1016\/j.heliyon.2022.e10366_bib50","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1016\/S0031-9422(00)80428-8","article-title":"Biological activities of lignans","volume":"23","author":"MacRae","year":"1984","journal-title":"Phytochemistry"},{"issue":"1","key":"10.1016\/j.heliyon.2022.e10366_bib51","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.jep.2007.07.009","article-title":"Ethnobotanical survey and antibacterial activity of some plants used in Guinean traditional medicine","volume":"114","author":"Magassouba","year":"2007","journal-title":"J.\u00a0Ethnopharmacol."},{"issue":"2","key":"10.1016\/j.heliyon.2022.e10366_bib52","first-page":"374","article-title":"Herbal medicines as an alternative source of therapy : a review","volume":"3","author":"Maqbool","year":"2019","journal-title":"World J. Pharm. Pharmaceut. Sci."},{"issue":"2","key":"10.1016\/j.heliyon.2022.e10366_bib53","doi-asserted-by":"crossref","first-page":"188","DOI":"10.3109\/13880209.2011.592537","article-title":"In vivo antiplasmodial activities of aqueous extract of Bridelia ferruginea stem bark against Plasmodium berghei berghei in mice","volume":"50","author":"Mbah","year":"2012","journal-title":"Pharmaceut. Biol."},{"key":"10.1016\/j.heliyon.2022.e10366_bib54","series-title":"Traditional Medicine and Pharmacopoeia: Contribution to the Revision of Ethnobotanical and Floristic Studies in Ghana","author":"Mshana","year":"2000"},{"issue":"16","key":"10.1016\/j.heliyon.2022.e10366_bib55","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.5897\/AJB2007.000-2287","article-title":"Phytochemical and antimicrobial screening of the crude extracts from the root, stem bark and leaves of Vitellaria paradoxa (GAERTN. F)","volume":"6","author":"Ndukwe","year":"2007","journal-title":"Afr. J. Biotechnol."},{"issue":"10","key":"10.1016\/j.heliyon.2022.e10366_bib56","first-page":"349","article-title":"Diuretic and natriuretic activity of an aqueous extract of Bridelia Ferruginea Benth.(Euphorbiaceae) in normal rats","volume":"2","author":"Nene-Bi","year":"2012","journal-title":"J.\u00a0Physiol. Pharmacol. Adv."},{"issue":"10","key":"10.1016\/j.heliyon.2022.e10366_bib57","first-page":"14","article-title":"Subchronic toxicity studies of the aqueous stem bark extract of Bridelia ferruginea in Wistar rats","volume":"5","author":"Nene-Bi","year":"2016","journal-title":"Bull Env Pharmacol Life Sci"},{"issue":"2","key":"10.1016\/j.heliyon.2022.e10366_bib58","first-page":"305","article-title":"Etudes phytochimique et pharmacologique de Bridelia ferruginea benth (euphorbiaceae) sur la motricite du Taenia coli de cobaye","volume":"5","author":"Nene Bi","year":"2009","journal-title":"Afr. Sci. Rev. Int. Sci. Technol."},{"issue":"3","key":"10.1016\/j.heliyon.2022.e10366_bib59","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.jep.2009.05.019","article-title":"The genus Bridelia : a phytochemical and ethnopharmacological review","volume":"124","author":"Ngueyem","year":"2009","journal-title":"J.\u00a0Ethnopharmacol."},{"issue":"5","key":"10.1016\/j.heliyon.2022.e10366_bib60","first-page":"759","article-title":"Effect of Bridelia ferruginea (euphorbiaceae) leaf extract on sucrose-induced glucose intolerance in rats","volume":"11","author":"Njamen","year":"2012","journal-title":"Trop. J. Pharmaceut. Res."},{"issue":"2","key":"10.1016\/j.heliyon.2022.e10366_bib61","first-page":"191","article-title":"Medicinal plants useful for malaria therapy in okeigbo, ondo state, southwest Nigeria","volume":"4","author":"Odugbemi","year":"2007","journal-title":"Afr. J. Tradit., Complementary Altern. Med."},{"issue":"1","key":"10.1016\/j.heliyon.2022.e10366_bib62","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0378-8741(99)00006-9","article-title":"Effects of the aqueous extract of Bridelia ferruginea stem bark on carrageenan-induced oedema and granuloma tissue formation in rats and mice","volume":"66","author":"Olajide","year":"1999","journal-title":"J.\u00a0Ethnopharmacol."},{"issue":"1-2","key":"10.1016\/j.heliyon.2022.e10366_bib63","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0378-8741(99)00201-9","article-title":"Studies on the anti-inflammatory and related pharmacological properties of the aqueous extract of Bridelia ferruginea stem bark","volume":"71","author":"Olajide","year":"2000","journal-title":"J.\u00a0Ethnopharmacol."},{"issue":"2-3","key":"10.1016\/j.heliyon.2022.e10366_bib64","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0378-8741(03)00219-8","article-title":"Anti-inflammatory properties of Bridelia ferruginea stem bark Inhibition of lipopolysaccaride-induced septic shock and vascular permeability","volume":"88","author":"Olajide","year":"2003","journal-title":"J.\u00a0Ethnopharmacol."},{"key":"10.1016\/j.heliyon.2022.e10366_bib65","series-title":"Medicinal Plants in Tropical West Africa","author":"Oliver-Bever","year":"1986"},{"issue":"3","key":"10.1016\/j.heliyon.2022.e10366_bib66","first-page":"1","article-title":"In-vitro antioxidant activities of the stem bark extract fractions of Bridelia ferruginea","volume":"4","author":"Oloyede","year":"2014","journal-title":"J.\u00a0Biol. Agric. Healthc."},{"issue":"3","key":"10.1016\/j.heliyon.2022.e10366_bib67","first-page":"246","article-title":"Invitro antioxidant activity of ethanolic extract of bridelia ferruginea (stem bark)","volume":"2","author":"Oloyede","year":"2012","journal-title":"Acad. Res. Int."},{"issue":"6","key":"10.1016\/j.heliyon.2022.e10366_bib68","doi-asserted-by":"crossref","first-page":"264","DOI":"10.15406\/ppij.2019.07.00262","article-title":"Evaluation of antidiabetic role of Bridelia ferruginea methanol leaf extract in streptozocin induced diabetic male wistar rats","volume":"7","author":"Onyenibe","year":"2019","journal-title":"Pharm Pharmacol Int J"},{"issue":"5","key":"10.1016\/j.heliyon.2022.e10366_bib69","first-page":"398","article-title":"Antimicrobial value of Olax subscorpioidea and Bridelia ferruginea on micro-organism isolates of dental infection","volume":"5","author":"Orabueze","year":"2016","journal-title":"J.\u00a0Pharmacogn. Phytochem."},{"issue":"5","key":"10.1016\/j.heliyon.2022.e10366_bib70","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/ptr.2650040506","article-title":"Coagulation of milk as an index of astringency of the bark extract of Bridelia ferruginea benth and lime juice for the formulation of a traditional gargle \u2018Ogun Efu","volume":"4","author":"Orafidiya","year":"1990","journal-title":"Phytother Res."},{"issue":"5","key":"10.1016\/j.heliyon.2022.e10366_bib71","doi-asserted-by":"crossref","first-page":"419","DOI":"10.31254\/phyto.2018.7503","article-title":"Toxicological assessment of the methanolic leaf extract of Bridelia ferrugelia","volume":"7","author":"Owoade","year":"2018","journal-title":"J.\u00a0phytopharm."},{"issue":"7","key":"10.1016\/j.heliyon.2022.e10366_bib72","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.5897\/AJB09.1072","article-title":"Antimicrobial and phytochemical analysis of leaves and bark extracts from Bridelia ferruginea","volume":"9","author":"Owoseni","year":"2010","journal-title":"Afr. J. Biotechnol."},{"issue":"3","key":"10.1016\/j.heliyon.2022.e10366_bib73","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1021\/acs.jnatprod.5b00873","article-title":"Antineoplastic agents. 585. Isolation of Bridelia ferruginea anticancer podophyllotoxins and synthesis of 4 - aza-podophyllotoxin structural modifications 1","volume":"79","author":"Pettit","year":"2016","journal-title":"J.\u00a0Nat. Prod."},{"issue":"2","key":"10.1016\/j.heliyon.2022.e10366_bib74","article-title":"Phytomedicine Plus Therapeutic and pharmacological efficacy of selective Indian medicinal plants \u2013 a review","volume":"1","author":"Prasathkumar","year":"2021","journal-title":"Phytomedicine"},{"issue":"4","key":"10.1016\/j.heliyon.2022.e10366_bib75","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1080\/10575630008041244","article-title":"A\u00a0new podophyllotoxin derivative from Bridelia ferruginea","volume":"14","author":"Rashid","year":"2000","journal-title":"Nat. Prod. Lett."},{"issue":"2","key":"10.1016\/j.heliyon.2022.e10366_bib76","doi-asserted-by":"crossref","first-page":"90","DOI":"10.3390\/nu8020090","article-title":"Myricetin: a dietary molecule with diverse biological activities","volume":"8","author":"Semwal","year":"2016","journal-title":"Nutrients"},{"issue":"4","key":"10.1016\/j.heliyon.2022.e10366_bib77","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0367-326X(02)00084-9","article-title":"Antimicrobial activity of Bridelia ferruginea leaves extracts","volume":"73","author":"Talla","year":"2002","journal-title":"Fitoterapia"},{"issue":"3","key":"10.1016\/j.heliyon.2022.e10366_bib78","doi-asserted-by":"crossref","first-page":"217","DOI":"10.5455\/jice.20150623090040","article-title":"Herbal medicine use among patients with chronic diseases","volume":"4","author":"Tulunay","year":"2015","journal-title":"J.\u00a0Intercult. Ethnopharmacol."},{"issue":"7216","key":"10.1016\/j.heliyon.2022.e10366_bib79","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1136\/bmj.319.7216.1050","article-title":"Herbal medicine","volume":"319","author":"Vickers","year":"1999","journal-title":"BMJ"},{"issue":"6","key":"10.1016\/j.heliyon.2022.e10366_bib80","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S1995-7645(11)60123-5","article-title":"A\u00a0comparative study of the ovicidal and larvicidal activities of aqueous and ethanolic extracts of pawpaw seeds Carica papaya (Caricaceae) on Heligmosomoides bakeri","volume":"4","author":"Wabo","year":"2011","journal-title":"Asian Pac. J. Trop. Med."},{"key":"10.1016\/j.heliyon.2022.e10366_bib81","series-title":"West African Health Organisation","year":"2013"}],"container-title":["Heliyon"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405844022016541?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405844022016541?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T09:00:11Z","timestamp":1772010011000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405844022016541"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":80,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["S2405844022016541"],"URL":"https:\/\/doi.org\/10.1016\/j.heliyon.2022.e10366","relation":{},"ISSN":["2405-8440"],"issn-type":[{"value":"2405-8440","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bridelia ferruginea Benth.; An ethnomedicinal, phytochemical, pharmacological and toxicological review","name":"articletitle","label":"Article Title"},{"value":"Heliyon","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.heliyon.2022.e10366","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"e10366"}}