{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T01:44:09Z","timestamp":1793238249126,"version":"4.5.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,31]],"date-time":"2022-12-31T00:00:00Z","timestamp":1672444800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heliyon"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.heliyon.2022.e12781","type":"journal-article","created":{"date-parts":[[2023,1,3]],"date-time":"2023-01-03T20:50:51Z","timestamp":1672779051000},"page":"e12781","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Efficiency evaluation of two estrus synchronization protocols in estrus response and conception rate of dairy cows in the Dalocha district, Ethiopia"],"prefix":"10.1016","volume":"9","author":[{"given":"Sharew Mekonnen","family":"Haile","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5144-3475","authenticated-orcid":false,"given":"Belete Kuraz","family":"Abebe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tigst Wendala","family":"Tesfa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.heliyon.2022.e12781_bib1","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.2527\/jas.2012-5611","article-title":"Preovulatory estradiol and the establishment and maintenance of pregnancy in suckled beef cows","volume":"91","author":"Jinks","year":"2013","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.heliyon.2022.e12781_bib2","series-title":"Identification of Indicator Traits of Fertility in the Postpartum Beef Cow","author":"Cushman","year":"2007"},{"key":"10.1016\/j.heliyon.2022.e12781_bib3","first-page":"85","article-title":"Control of estrus in cows","author":"Lamb","year":"2012","journal-title":"Proc. Appl. Reprod. Strateg. Beef Cattle"},{"key":"10.1016\/j.heliyon.2022.e12781_bib4","series-title":"Oestrus Synchronization for Accelerated Delivery of Improved Dairy Genetics in Ethiopia: Results from Action Research and Development Interventions","author":"Gizaw","year":"2016"},{"key":"10.1016\/j.heliyon.2022.e12781_bib5","first-page":"402","volume":"vol. 68588","author":"Rick","year":"2013"},{"key":"10.1016\/j.heliyon.2022.e12781_bib6","doi-asserted-by":"crossref","first-page":"3045","DOI":"10.3168\/jds.2007-0625","article-title":"Effect of synchronization protocols on follicular development and estradiol and progesterone concentrations of dairy heifers","volume":"91","author":"Stevenson","year":"2008","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.heliyon.2022.e12781_bib7","doi-asserted-by":"crossref","DOI":"10.5455\/vetworld.2012.453-458","article-title":"Estrus induction and fertility response in delayed pubertal Kankrej heifers treated with norgestomet ear implant","volume":"5","author":"Chaudhari","year":"2012","journal-title":"Vet. World"},{"key":"10.1016\/j.heliyon.2022.e12781_bib8","first-page":"94","article-title":"Assessment of reproductive performance and problems in crossbred (Holstein Friesian X Zebu) dairy cattle in and around Mekelle, Tigray, Ethiopia","volume":"3","author":"Mekonnin","year":"2015","journal-title":"Ethiop. Anim. Vet. Sci."},{"key":"10.1016\/j.heliyon.2022.e12781_bib9","series-title":"Proc. 15th Congr. FAVA","first-page":"243","article-title":"In vivo Sex fixing in Dairy Animals to produce female progenies","author":"Aulakh","year":"2008"},{"key":"10.1016\/j.heliyon.2022.e12781_bib10","series-title":"Effects of Prostaglandin Administration Frequency, Artificial Insemination Timing and Breed on Fertility of Cows and Heifers in Eastern Zone of Tigray Region","author":"Gugssa","year":"2015"},{"key":"10.1016\/j.heliyon.2022.e12781_bib11","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1051\/rnd:2006003","article-title":"Aetiology and pathogenesis of cystic ovarian follicles in dairy cattle: a review","volume":"46","author":"Vanholder","year":"2006","journal-title":"Reprod. Nutr. Dev."},{"key":"10.1016\/j.heliyon.2022.e12781_bib12","first-page":"221","article-title":"Oestrus performance of boran and boranx Holstein fresian crossbred cattle synchronized with a protocol based on estradiol benzoate or gonadotrophin-releasing hormone","volume":"45","author":"Million","year":"2011","journal-title":"Kasetsart J. (Nat. Sci."},{"key":"10.1016\/j.heliyon.2022.e12781_bib13","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0378-4320(84)90003-4","article-title":"Analyses of the variation in the interval from an injection of prostaglandin F2\u03b1 to oestrus as a method of studying patterns of follicle development during dioestrus in dairy cows","volume":"6","author":"Macmillan","year":"1984","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.heliyon.2022.e12781_bib14","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/9914095","article-title":"Challenges and opportunities on estrus synchronization and mass artificial insemination in dairy cows for smallholders in Ethiopia","volume":"2021","author":"Abebe","year":"2021","journal-title":"Int. J. Zool."},{"key":"10.1016\/j.heliyon.2022.e12781_bib15","series-title":"Evaluation of the Reproductive Performance of Crossbred (Hf X Zebu) Dairy Cows and Artificial Insemination Service Efficiency in and Around Adigrat","author":"Birhanemeskel","year":"2014"},{"key":"10.1016\/j.heliyon.2022.e12781_bib17","series-title":"Response of Cross Breed and Local Cows to Estrus Synchronisation Using a Prostaglandin or a Combination of Prostalglandin and Progestrone","author":"Mwanza","year":"2012"},{"key":"10.1016\/j.heliyon.2022.e12781_bib18","series-title":"Technological Options and Approaches to Improve Smallholder Access to Desirable Animal Genetic Material for Dairy Development: IPMS Experience with Hormonal Oestrus Synchronization and Mass Insemination in Ethiopia","author":"Tegegne","year":"2012"},{"key":"10.1016\/j.heliyon.2022.e12781_bib19","first-page":"99","article-title":"The effect of one shot prostaglandin on estrus synchronization of local and Holstein friesian cattle in and around Wukro Kilte Awulaelo District, Northern Ethiopia","volume":"5","author":"Gebrehiwot","year":"2015","journal-title":"J. Biol. Agricult. Healthc."},{"key":"10.1016\/j.heliyon.2022.e12781_bib20","series-title":"Assessment of Breeding Practice and Evaluation of Estrus Synchronization of Dairy Cattle in Sidama Zone","author":"Debir","year":"2016"},{"key":"10.1016\/j.heliyon.2022.e12781_bib21","first-page":"19","article-title":"Effect of age, parity and breed on conception rate and number of service per conception in artificially inseminated cows","volume":"2","author":"Khan","year":"2015","journal-title":"Age"},{"key":"10.1016\/j.heliyon.2022.e12781_bib22","series-title":"Effect of Breed, Parity and Body Condition on Efficacy of Double and Single PGF2\u03b1 Bovine Estrus Synchronization Protocol in Boran and Crossbreed Dairy Cattle in Bishoftu","author":"Ejigayehu","year":"2018"},{"key":"10.1016\/j.heliyon.2022.e12781_bib23","series-title":"Assessment of Breeding Practices and Evaluation of Mass Oestrus Syncronization and Mass Insemination Techniques in Dairy Cattle in West Shoa Zone","author":"Worku","year":"2015"},{"key":"10.1016\/j.heliyon.2022.e12781_bib24","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3329\/bvet.v35i1-2.53384","article-title":"Pregnancy rate and associated factors in dairy cows of Bangladesh","volume":"35","author":"Al Amin","year":"2018","journal-title":"Bangladesh Vet."},{"key":"10.1016\/j.heliyon.2022.e12781_bib25","doi-asserted-by":"crossref","first-page":"3951","DOI":"10.3168\/jds.2014-8656","article-title":"Changes in mammary metabolism in response to the provision of an ideal amino acid profile at 2 levels of metabolizable protein supply in dairy cows: consequences on efficiency","volume":"98","author":"Haque","year":"2015","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.heliyon.2022.e12781_bib26","first-page":"45","article-title":"Factors that limit first service pregnancy rate in cows at char management of Bangladesh","volume":"215","author":"Paul","year":"2013","journal-title":"Parity"},{"key":"10.1016\/j.heliyon.2022.e12781_bib27","doi-asserted-by":"crossref","first-page":"3208","DOI":"10.2527\/jas1988.66123208x","article-title":"Postpartum reproduction in protein restricted beef cows: effect on the hypothalamic-pituitary-ovarian axis","volume":"66","author":"Nolan","year":"1988","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.heliyon.2022.e12781_bib28","doi-asserted-by":"crossref","first-page":"93","DOI":"10.20884\/1.jap.2017.19.2.616","article-title":"Evaluation of two estrus synchronization protocols in dairy cattle at North Shoa zone Ethiopia","volume":"19","author":"Chanyalew","year":"2018","journal-title":"Anim. Prod."},{"key":"10.1016\/j.heliyon.2022.e12781_bib29","doi-asserted-by":"crossref","DOI":"10.5455\/vetworld.2013.413-415","article-title":"Effect of prostaglandin on estrus response and conception rate in lactating ongole cows","volume":"6","author":"Ramana","year":"2013","journal-title":"Vet. World"},{"key":"10.1016\/j.heliyon.2022.e12781_bib30","series-title":"Int. Work. Farm Size","article-title":"Impact of production system shift and land fragmentation on livestock production: the case of Fogera District","author":"Adebabay","year":"2013"},{"key":"10.1016\/j.heliyon.2022.e12781_bib31","first-page":"218","article-title":"A comparative study on evaluation of three synchronization protocols at field level in bovines","volume":"62","author":"Gupta","year":"2009","journal-title":"Indian J. Dairy Sci."},{"key":"10.1016\/j.heliyon.2022.e12781_bib32","series-title":"Improvement of Cattle Production in Myanmar through the Use of Progesterone RIA to Increase Efficiency and Quality of Artificial Insemination Services","author":"Than","year":"2001"},{"key":"10.1016\/j.heliyon.2022.e12781_bib33","doi-asserted-by":"crossref","first-page":"4488","DOI":"10.3168\/jds.2010-4126","article-title":"Evaluation of protocols to synchronize estrus and ovulation in seasonal calving pasture-based dairy production systems","volume":"94","author":"Herlihy","year":"2011","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.heliyon.2022.e12781_bib34","first-page":"845","article-title":"Post AI conception rate in cattle at Rajarhat, Kurigram, Bangladesh","volume":"6","author":"Khatun","year":"2014","journal-title":"Wayamba J. Anim. Sci."},{"key":"10.1016\/j.heliyon.2022.e12781_bib35","first-page":"349","article-title":"Determination of factors that affect the pregnancy rate of cows after artificial insemination at Monirampur Upazila of Jessore District of Bangladesh","volume":"31","author":"Hossain","year":"2016","journal-title":"J. Embryo Transf."}],"container-title":["Heliyon"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405844022040695?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405844022040695?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T10:00:33Z","timestamp":1765360833000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405844022040695"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["S2405844022040695"],"URL":"https:\/\/doi.org\/10.1016\/j.heliyon.2022.e12781","relation":{},"ISSN":["2405-8440"],"issn-type":[{"value":"2405-8440","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficiency evaluation of two estrus synchronization protocols in estrus response and conception rate of dairy cows in the Dalocha district, Ethiopia","name":"articletitle","label":"Article Title"},{"value":"Heliyon","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.heliyon.2022.e12781","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"e12781"}}