{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T22:04:45Z","timestamp":1784930685794,"version":"3.55.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T00:00:00Z","timestamp":1693958400000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heliyon"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.heliyon.2023.e19954","type":"journal-article","created":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T16:57:33Z","timestamp":1694105853000},"page":"e19954","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Hypovitaminosis D, objective oral dryness, and fungal hyphae as three precipitating factors for a subset of secondary burning mouth syndrome"],"prefix":"10.1016","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7462-804X","authenticated-orcid":false,"given":"Yang","family":"Gu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Baldwin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl","family":"Canning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl. 1","key":"10.1016\/j.heliyon.2023.e19954_bib1","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/odi.13067","article-title":"World Workshop on Oral Medicine VII: burning mouth syndrome: a systematic review of disease definitions and diagnostic criteria utilized in randomized clinical trials","volume":"25","author":"Ariyawardana","year":"2019","journal-title":"Oral Dis."},{"key":"10.1016\/j.heliyon.2023.e19954_bib2","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1111\/j.1600-0714.1999.tb02052.x","article-title":"Burning mouth syndrome: prevalence and associated factors","volume":"28","author":"Bergdahi","year":"1999","journal-title":"J. Oral Pathol. Med."},{"key":"10.1016\/j.heliyon.2023.e19954_bib3","series-title":"IASP Orofacial Pain Fact Sheet. Burning Mouth Syndrome","year":"2016"},{"issue":"4","key":"10.1016\/j.heliyon.2023.e19954_bib4","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1177\/154411130301400405","article-title":"Update on Burning mouth syndrome: overview and patient management","volume":"14","author":"Scala","year":"2003","journal-title":"Crit. Rev. Oral Biol. Med."},{"key":"10.1016\/j.heliyon.2023.e19954_bib5","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1111\/ijd.13634","article-title":"Burning mouth syndrome: results of screening tests for vitamin and mineral deficiencies, thyroid hormone, and glucose levels\u2014experience at Mayo Clinic over a decade","volume":"56","author":"Verenzuela","year":"2017","journal-title":"Int. J. Dermatol."},{"issue":"1029","key":"10.1016\/j.heliyon.2023.e19954_bib6","first-page":"e1","article-title":"Candidiasis and other bacterial infections among patients diagnosed with burning mouth syndrome","volume":"58","author":"Jankovskis","year":"2022","journal-title":"Medicina"},{"issue":"15","key":"10.1016\/j.heliyon.2023.e19954_bib7","first-page":"e1","article-title":"Oral candidiasis: a disease of opportunity","volume":"6","author":"Vila","year":"2020","journal-title":"Journal of Fungi"},{"issue":"7","key":"10.1016\/j.heliyon.2023.e19954_bib8","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1586\/14787210.2014.916210","article-title":"Pathogenicity mechanisms and host response during oral Candida albicans","volume":"12","author":"Hebecker","year":"2014","journal-title":"Expert Rev. Anti-infective Ther."},{"issue":"1656","key":"10.1016\/j.heliyon.2023.e19954_bib9","first-page":"1","article-title":"Vitamin D: nutrient, hormone, and immunomodulator","volume":"10","author":"Sassi","year":"2018","journal-title":"Nutrients"},{"key":"10.1016\/j.heliyon.2023.e19954_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.dentre.2022.100036","article-title":"Burning mouth syndrome: etiology, clinical presentations, and treatment alternatives","volume":"2","author":"Alsabbagh","year":"2022","journal-title":"Dentistry Review"},{"issue":"11","key":"10.1016\/j.heliyon.2023.e19954_bib11","first-page":"1","article-title":"Interventions for treating burning mouth syndrome","author":"McMillan","year":"2016","journal-title":"Cochrane Database Syst. Rev."},{"issue":"50","key":"10.1016\/j.heliyon.2023.e19954_bib12","doi-asserted-by":"crossref","first-page":"665","DOI":"10.3748\/wjg.v19.i5.665","article-title":"Burning mouth syndrome","volume":"19","author":"Gurvits","year":"2013","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.heliyon.2023.e19954_bib13","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/s00784-010-0419-5","article-title":"Risk factors in burning mouth syndrome: a case-control study based on patient records","volume":"15","author":"Netto","year":"2011","journal-title":"Clin. Oral Invest."},{"key":"10.1016\/j.heliyon.2023.e19954_bib14","article-title":"AAOM clinical practice statement","year":"2016","journal-title":"Subjectivity: clinical management of cancer therapy-induced salivary gland hypofunction and xerostomia"},{"issue":"5","key":"10.1016\/j.heliyon.2023.e19954_bib15","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1007\/s00198-010-1362-7","article-title":"25-Hydroxyvitamin D in Canadian Adults: biological, environmental, and behavioral correlation","volume":"22","author":"Greene-Finestone","year":"2011","journal-title":"Ostoporos Int"},{"key":"10.1016\/j.heliyon.2023.e19954_bib16","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.mib.2019.04.005","article-title":"Pathogenesis in Candida albicans","volume":"52","author":"Kadosh","year":"2019","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.heliyon.2023.e19954_bib17","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1038\/nrmicro2636","article-title":"Growth of Candida albicans hyphae","volume":"9","author":"Sudbery","year":"2011","journal-title":"Nat. Rev. Microbiol."},{"issue":"3","key":"10.1016\/j.heliyon.2023.e19954_bib18","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s12275-016-5514-0","article-title":"Interaction of Candida Albicans with host cells: virulence factors, host defense, escape strategies, and the microbiota","volume":"54","author":"Hofs","year":"2016","journal-title":"J. Microbiol."},{"issue":"9","key":"10.1016\/j.heliyon.2023.e19954_bib19","doi-asserted-by":"crossref","first-page":"677","DOI":"10.14348\/molcells.2017.0026","article-title":"Vitamin D proliferates vaginal epithelium through RhoA expression in postmenopausal atrophic vagina tissue","volume":"40","author":"Lee","year":"2017","journal-title":"Mol. Cell."},{"key":"10.1016\/j.heliyon.2023.e19954_bib20","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/S0003-9969(01)00082-6","article-title":"A comparative light-microscopic, electron-microscopic, and chemical study of human vaginal and buccal epithelium","volume":"46","author":"Thompson","year":"2001","journal-title":"Arch. Oral Biol."},{"issue":"2","key":"10.1016\/j.heliyon.2023.e19954_bib21","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.4110\/in.2020.20.e12","article-title":"Vitamin D-cathelicidin Axis: at the crossroads between protective immunity and pathological inflammation during infection","volume":"20","author":"Chung","year":"2020","journal-title":"Immune Network"},{"key":"10.1016\/j.heliyon.2023.e19954_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0003-9969(80)90147-8","article-title":"The prevalence and intra-oral distribution of Candida Albicans in Man","volume":"25","author":"Arendorf","year":"1980","journal-title":"Arch. Oral Biol."},{"issue":"1","key":"10.1016\/j.heliyon.2023.e19954_bib23","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1080\/19336950.2021.1905248","article-title":"TRPV1 channels as a newly identified target for vitamin D","volume":"15","author":"Long","year":"2021","journal-title":"Channels"},{"key":"10.1016\/j.heliyon.2023.e19954_bib24","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0169-328X(02)00441-2","article-title":"Vanilloid receptor subtype-1 (VR1) is specifically localized to taste papillae","volume":"107","author":"Ishida","year":"2002","journal-title":"Mol. Brain Res."},{"key":"10.1016\/j.heliyon.2023.e19954_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jchemneu.2010.10.001","article-title":"Vitamin D receptor and enzyme expression in dorsal root ganglia of adult female rats: modulation by ovarian hormones","volume":"41","author":"Tague","year":"2011","journal-title":"J. Chem. Neuroanat."},{"key":"10.1016\/j.heliyon.2023.e19954_bib26","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1111\/odi.13650","article-title":"Vitamin D oral gel for prevention of radiation-induced oral mucositis: a randomized clinical trial","volume":"27","author":"Bakr","year":"2021","journal-title":"Oral Dis."},{"key":"10.1016\/j.heliyon.2023.e19954_bib27","series-title":"Headache Classification Committee of the International Headache Society","first-page":"1","year":"2018"}],"container-title":["Heliyon"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405844023071621?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405844023071621?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T21:25:28Z","timestamp":1784928328000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405844023071621"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":27,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["S2405844023071621"],"URL":"https:\/\/doi.org\/10.1016\/j.heliyon.2023.e19954","relation":{},"ISSN":["2405-8440"],"issn-type":[{"value":"2405-8440","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypovitaminosis D, objective oral dryness, and fungal hyphae as three precipitating factors for a subset of secondary burning mouth syndrome","name":"articletitle","label":"Article Title"},{"value":"Heliyon","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.heliyon.2023.e19954","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"e19954"}}