{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T14:04:44Z","timestamp":1784210684127,"version":"3.55.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,10]],"date-time":"2024-03-10T00:00:00Z","timestamp":1710028800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heliyon"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.heliyon.2024.e27993","type":"journal-article","created":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T14:03:58Z","timestamp":1710770638000},"page":"e27993","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Performance of ATT and UDFF in the diagnosis of non-alcoholic fatty liver: An animal experiment"],"prefix":"10.1016","volume":"10","author":[{"given":"Huihui","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiming","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahao","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pingping","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danlei","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyuan","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoying","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingjie","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.heliyon.2024.e27993_bib1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S2468-1253(19)30342-5","article-title":"Liver diseases in the Asia-Pacific region: a Lancet Gastroenterology & Hepatology commission","volume":"5","author":"Sarin","year":"2020","journal-title":"Lancet Gastroenterol. Hepatol."},{"key":"10.1016\/j.heliyon.2024.e27993_bib2","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.cgh.2014.04.014","article-title":"Fibrosis progression in nonalcoholic fatty liver vs nonalcoholic steatohepatitis: a systematic review and meta-analysis of paired-biopsy studies","volume":"13","author":"Singh","year":"2015","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"10.1016\/j.heliyon.2024.e27993_bib3","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.bbe.2018.03.008","article-title":"Multi-modal framework for automatic detection of diagnostically important regions in nonalcoholic fatty liver ultrasonic images","volume":"38","author":"Bharath","year":"2018","journal-title":"Biocybern. Biomed. Eng."},{"key":"10.1016\/j.heliyon.2024.e27993_bib4","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1007\/s12072-018-9843-4","article-title":"Repeated liver stiffness measurement compared with paired liver biopsy in patients with non-alcoholic fatty liver disease","volume":"12","author":"Kamarajah","year":"2018","journal-title":"Hepatol. Int."},{"key":"10.1016\/j.heliyon.2024.e27993_bib5","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.jhep.2013.04.027","article-title":"A systematic review of follow-up biopsies reveals disease progression in patients with non-alcoholic fatty liver","volume":"59","author":"Pais","year":"2013","journal-title":"J. Hepatol."},{"key":"10.1016\/j.heliyon.2024.e27993_bib6","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1016\/j.jhep.2022.01.011","article-title":"Complexity of ballooned hepatocyte feature recognition: defining a training atlas for artificial intelligence-based imaging in NAFLD","volume":"76","author":"Brunt","year":"2022","journal-title":"J. Hepatol."},{"key":"10.1016\/j.heliyon.2024.e27993_bib7","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.jceh.2019.05.001","article-title":"Magnitude of nonalcoholic fatty liver disease: western perspective","volume":"9","author":"Samji","year":"2019","journal-title":"J Clin Exp Hepatol"},{"key":"10.1016\/j.heliyon.2024.e27993_bib8","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.jhep.2017.10.031","article-title":"Preclinical models of non-alcoholic fatty liver disease","volume":"68","author":"Santhekadur","year":"2018","journal-title":"J. Hepatol."},{"key":"10.1016\/j.heliyon.2024.e27993_bib9","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1152\/japplphysiol.00013.2021","article-title":"High fat high sucrose diet-induced dyslipidemia in Guinea pigs","volume":"130","author":"Muller","year":"2021","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.heliyon.2024.e27993_bib10","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.mri.2018.11.013","article-title":"Evaluation of hepatic function using dynamic contrast-enhanced magnetic resonance imaging in melanocortin 4 receptor-deficient mice as a model of nonalcoholic steatohepatitis","volume":"57","author":"Yamada","year":"2019","journal-title":"Magn. Reson. Imaging"},{"key":"10.1016\/j.heliyon.2024.e27993_bib11","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1002\/hep.30333","article-title":"Mouse models of nonalcoholic steatohepatitis: toward optimization of their relevance to human nonalcoholic steatohepatitis","volume":"69","author":"Farrell","year":"2019","journal-title":"Hepatology"},{"key":"10.1016\/j.heliyon.2024.e27993_bib12","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1017\/S0954422413000152","article-title":"Use of pigs as a potential model for research into dietary modulation of the human gut microbiota","volume":"26","author":"Heinritz","year":"2013","journal-title":"Nutr. Res. Rev."},{"key":"10.1016\/j.heliyon.2024.e27993_bib13","doi-asserted-by":"crossref","first-page":"E187","DOI":"10.1152\/ajpendo.00052.2022","article-title":"Dietary fat composition shapes bile acid metabolism and severity of liver injury in a pig model of pediatric NAFLD","volume":"323","author":"Manjar\u00edn","year":"2022","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.heliyon.2024.e27993_bib14","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3390\/jcm10050965","article-title":"Attenuation imaging with ultrasound as a novel evaluation method for liver steatosis","volume":"10","author":"Hsu","year":"2021","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.heliyon.2024.e27993_bib15","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1148\/radiol.2020192437","article-title":"Update to the society of radiologists in ultrasound liver elastography consensus statement","volume":"296","author":"Barr","year":"2020","journal-title":"Radiology"},{"key":"10.1016\/j.heliyon.2024.e27993_bib16","doi-asserted-by":"crossref","first-page":"997","DOI":"10.2214\/AJR.11.6677","article-title":"Hepatorenal index as an accurate, simple, and effective tool in screening for steatosis","volume":"199","author":"Marshall","year":"2012","journal-title":"Am. J. Roentgenol."},{"key":"10.1016\/j.heliyon.2024.e27993_bib17","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1007\/s00247-022-05313-x","article-title":"Diagnostic performance of ultrasound hepatorenal index for the diagnosis of hepatic steatosis in children","volume":"52","author":"Frankland","year":"2022","journal-title":"Pediatr. Radiol."},{"key":"10.1016\/j.heliyon.2024.e27993_bib18","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1002\/path.4829","article-title":"Animal models of non-alcoholic fatty liver disease: current perspectives and recent advances","volume":"241","author":"Lau","year":"2017","journal-title":"J. Pathol."},{"key":"10.1016\/j.heliyon.2024.e27993_bib19","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1002\/hep.20701","article-title":"Design and validation of a histological scoring system for nonalcoholic fatty liver disease","volume":"41","author":"Kleiner","year":"2005","journal-title":"Hepatology"},{"key":"10.1016\/j.heliyon.2024.e27993_bib20","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1002\/hep.24376","article-title":"Endpoints and clinical trial design for nonalcoholic steatohepatitis","volume":"54","author":"Sanyal","year":"2011","journal-title":"Hepatology"},{"key":"10.1016\/j.heliyon.2024.e27993_bib21","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1002\/hep.22904","article-title":"Nutritional model of steatohepatitis and metabolic syndrome in the ossabaw miniature swine","volume":"50","author":"Lee","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.heliyon.2024.e27993_bib22","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.trsl.2015.10.001","article-title":"Diet-induced dyslipidemia leads to nonalcoholic fatty liver disease and oxidative stress in Guinea pigs","volume":"168","author":"Tveden-Nyborg","year":"2016","journal-title":"Transl. Res."},{"key":"10.1016\/j.heliyon.2024.e27993_bib23","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.1080\/10495398.2022.2088548","article-title":"Establishment of type 2 diabetes mellitus models using streptozotocin after 3 months high-fat diet in Bama minipigs","volume":"34","author":"Zhao","year":"2023","journal-title":"Anim. Biotechnol."},{"key":"10.1016\/j.heliyon.2024.e27993_bib24","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.dsx.2018.03.016","article-title":"Non-alcoholic fatty liver disease and associated dietary and lifestyle risk factors","volume":"12","author":"Al-Dayyat","year":"2018","journal-title":"Diabetes Metab. Syndrome-Clin. Res. Rev."},{"key":"10.1016\/j.heliyon.2024.e27993_bib25","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1053\/j.gastro.2016.10.026","article-title":"Magnetic resonance elastography vs transient elastography in detection of fibrosis and noninvasive measurement of steatosis in patients with biopsy-proven nonalcoholic fatty liver disease","volume":"152","author":"Park","year":"2017","journal-title":"Gastroenterology"},{"key":"10.1016\/j.heliyon.2024.e27993_bib26","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1002\/hep.28012","article-title":"Quantitative magnetic resonance imaging of hepatic steatosis: validation in ex vivo human livers","volume":"62","author":"Bannas","year":"2015","journal-title":"Hepatology"},{"key":"10.1016\/j.heliyon.2024.e27993_bib27","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1016\/j.cgh.2021.11.003","article-title":"Utility of ultrasound-guided attenuation parameter for grading steatosis with reference to MRI-PDFF in a large cohort","volume":"20","author":"Imajo","year":"2022","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"10.1016\/j.heliyon.2024.e27993_bib28","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1111\/hepr.13179","article-title":"Novel quantitative assessment system of liver steatosis using a newly developed attenuation measurement method","volume":"48","author":"Tamaki","year":"2018","journal-title":"Hepatol. Res."},{"key":"10.1016\/j.heliyon.2024.e27993_bib29","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1007\/s11547-023-01693-8","article-title":"Ultrasound-derived fat fraction for detection of hepatic steatosis and quantification of liver fat content","volume":"128","author":"De Robertis","year":"2023","journal-title":"Radiol. Med."},{"key":"10.1016\/j.heliyon.2024.e27993_bib30","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.jnutbio.2015.09.029","article-title":"A nutritional nonalcoholic steatohepatitis minipig model","volume":"28","author":"Li","year":"2016","journal-title":"JNB (J. Nutr. Biochem.)"}],"container-title":["Heliyon"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405844024040246?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405844024040246?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T13:12:25Z","timestamp":1784207545000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405844024040246"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":30,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["S2405844024040246"],"URL":"https:\/\/doi.org\/10.1016\/j.heliyon.2024.e27993","relation":{},"ISSN":["2405-8440"],"issn-type":[{"value":"2405-8440","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Performance of ATT and UDFF in the diagnosis of non-alcoholic fatty liver: An animal experiment","name":"articletitle","label":"Article Title"},{"value":"Heliyon","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.heliyon.2024.e27993","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"e27993"}}