{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T14:03:27Z","timestamp":1784210607027,"version":"3.55.0"},"update-to":[{"DOI":"10.1016\/j.heliyon.2024.e28016","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T00:00:00Z","timestamp":1713139200000}}],"reference-count":67,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,11]],"date-time":"2024-03-11T00:00:00Z","timestamp":1710115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009391","name":"University of Tabuk","doi-asserted-by":"publisher","award":["S-1442-0164"],"award-info":[{"award-number":["S-1442-0164"]}],"id":[{"id":"10.13039\/100009391","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heliyon"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.heliyon.2024.e28016","type":"journal-article","created":{"date-parts":[[2024,3,20]],"date-time":"2024-03-20T20:27:54Z","timestamp":1710966474000},"page":"e28016","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["RETRACTED: Quercetin attenuated ischemic stroke induced neurodegeneration by modulating glutamatergic and synaptic signaling pathways"],"prefix":"10.1016","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5415-2179","authenticated-orcid":false,"given":"Fawad Ali","family":"Shah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faisal","family":"Albaqami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4909-7723","authenticated-orcid":false,"given":"Abdullah","family":"Alattar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reem","family":"Alshaman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sawsan A.","family":"Zaitone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Attia M.","family":"Gabr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdel-Moneim Hafez","family":"Abdel-Moneim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"El dosoky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phil Ok","family":"Koh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.heliyon.2024.e28016_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000352050","article-title":"The ASCOD phenotyping of ischemic stroke (Updated ASCO Phenotyping)","volume":"36","author":"Amarenco","year":"2013","journal-title":"Cerebrovasc. Dis."},{"key":"10.1016\/j.heliyon.2024.e28016_bib2","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1161\/STROKEAHA.116.012619","article-title":"Outcome after thrombectomy and intravenous thrombolysis in patients with acute ischemic stroke: a prospective observational study","volume":"47","author":"Minnerup","year":"2016","journal-title":"Stroke"},{"key":"10.1016\/j.heliyon.2024.e28016_bib3","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1007\/s12975-010-0032-6","article-title":"Quantitative temporal profiles of penumbra and infarction during permanent middle cerebral artery occlusion in rats","volume":"1","author":"Foley","year":"2010","journal-title":"Transl Stroke Res"},{"key":"10.1016\/j.heliyon.2024.e28016_bib4","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.brainres.2003.10.028","article-title":"Extension of cerebral hypoperfusion and ischaemic pathology beyond MCA territory after intraluminal filament occlusion in C57Bl\/6J mice","volume":"997","author":"McColl","year":"2004","journal-title":"Brain Res."},{"key":"10.1016\/j.heliyon.2024.e28016_bib5","doi-asserted-by":"crossref","DOI":"10.12688\/f1000research.19317.1","article-title":"Interactions between the hippocampus, prefrontal cortex, and amygdala support complex learning and memory","volume":"8","author":"Yavas","year":"2019","journal-title":"F1000Res"},{"key":"10.1016\/j.heliyon.2024.e28016_bib6","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/35039075","article-title":"Postsynaptic organisation and regulation of excitatory synapses","volume":"1","author":"Scannevin","year":"2000","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.heliyon.2024.e28016_bib7","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1038\/nrn2911","article-title":"Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders","volume":"11","author":"Hardingham","year":"2010","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.heliyon.2024.e28016_bib8","doi-asserted-by":"crossref","first-page":"2846","DOI":"10.1523\/JNEUROSCI.0116-07.2007","article-title":"NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo","volume":"27","author":"Liu","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.heliyon.2024.e28016_bib9","article-title":"Icaritin alleviates glutamate-induced neuronal damage by inactivating GluN2B-containing NMDARs through the ERK\/DAPK1 pathway","volume":"15","author":"Liu","year":"2021","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.heliyon.2024.e28016_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13041-018-0357-8","article-title":"Targeting NMDA receptors in stroke: new hope in neuroprotection","volume":"11","author":"Wu","year":"2018","journal-title":"Mol. Brain"},{"key":"10.1016\/j.heliyon.2024.e28016_bib11","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.2174\/092986708784310431","article-title":"Dietary antioxidants as potential pharmacological agents for ischemic stroke","volume":"15","author":"Cherubini","year":"2008","journal-title":"Curr. Med. Chem."},{"issue":"15","key":"10.1016\/j.heliyon.2024.e28016_bib12","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.2174\/1389557519666190617150051","article-title":"The roles of flavonols\/flavonoids in neurodegeneration and neuroinflammation","volume":"20","author":"Calis","year":"2020","journal-title":"Mini Rev. Med. Chem."},{"key":"10.1016\/j.heliyon.2024.e28016_bib13","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.3389\/fphar.2018.01383","article-title":"Neuroprotective effect of quercetin against the detrimental effects of lps in the adult mouse brain","volume":"9","author":"Khan","year":"2018","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.heliyon.2024.e28016_bib14","doi-asserted-by":"crossref","first-page":"6076","DOI":"10.1007\/s12035-017-0798-6","article-title":"Natural dietary supplementation of anthocyanins via PI3K\/Akt\/Nrf2\/HO-1 Pathways mitigate oxidative stress, neurodegeneration, and memory impairment in a mouse model of Alzheimer's Disease","volume":"55","author":"Ali","year":"2018","journal-title":"Mol. Neurobiol."},{"issue":"1","key":"10.1016\/j.heliyon.2024.e28016_bib15","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s12035-015-9604-5","article-title":"Anthocyanins reversed D-galactose-induced oxidative stress and neuroinflammation mediated cognitive impairment in adult rats","volume":"54","author":"Rehman","year":"2017","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.heliyon.2024.e28016_bib16","doi-asserted-by":"crossref","first-page":"63","DOI":"10.5625\/lar.2013.29.2.63","article-title":"Ferulic acid regulates the AKT\/GSK-3\u03b2\/CRMP-2 signaling pathway in a middle cerebral artery occlusion animal model","volume":"29","author":"Gim","year":"2013","journal-title":"Lab Anim Res"},{"key":"10.1016\/j.heliyon.2024.e28016_bib17","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.jss.2015.10.025","article-title":"Identification of proteins regulated by curcumin in cerebral ischemia","volume":"201","author":"Shah","year":"2016","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.heliyon.2024.e28016_bib18","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1292\/jvms.21-0013","article-title":"Identification of regulated proteins by resveratrol in glutamate-induced cortical injury of newborn rats","volume":"83","author":"Gim","year":"2021","journal-title":"J. Vet. Med. Sci."},{"key":"10.1016\/j.heliyon.2024.e28016_bib19","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1007\/s11064-011-0458-6","article-title":"Quercetin protects against oxidative stress associated damages in a rat model of transient focal cerebral ischemia and reperfusion","volume":"36","author":"Ahmad","year":"2011","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.heliyon.2024.e28016_bib20","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.cbi.2018.02.017","article-title":"Isoquercetin attenuates oxidative stress and neuronal apoptosis after ischemia\/reperfusion injury via Nrf2-mediated inhibition of the NOX4\/ROS\/NF-\u03baB pathway","volume":"284","author":"Dai","year":"2018","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.heliyon.2024.e28016_bib21","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.bbrc.2016.07.068","article-title":"Quercetin ameliorates ischemia\/reperfusion-induced cognitive deficits by inhibiting ASK1\/JNK3\/caspase-3 by enhancing the Akt signaling pathway","volume":"478","author":"Pei","year":"2016","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.heliyon.2024.e28016_bib22","doi-asserted-by":"crossref","first-page":"3688","DOI":"10.3892\/mmr.2015.3857","article-title":"Neuroprotective effects of quercetin in a mouse model of brain ischemic\/reperfusion injury via anti-apoptotic mechanisms based on the Akt pathway","volume":"12","author":"Lei","year":"2015","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.heliyon.2024.e28016_bib23","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.phrs.2009.08.006","article-title":"Effect of dietary quercetin on brain quercetin levels and the expression of antioxidant and Alzheimer's disease relevant genes in mice","volume":"61","author":"Huebbe","year":"2010","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.heliyon.2024.e28016_bib24","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1093\/jn\/135.7.1718","article-title":"Tissue distribution of quercetin in rats and pigs","volume":"135","author":"de Boer","year":"2005","journal-title":"J. Nutr."},{"key":"10.1016\/j.heliyon.2024.e28016_bib25","doi-asserted-by":"crossref","first-page":"249","DOI":"10.3892\/etm.2011.382","article-title":"Effects of quercetin on apoptosis, NF-\u03baB and NOS gene expression in renal ischemia\/reperfusion injury","volume":"3","author":"Kenan Kinaci","year":"2012","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.heliyon.2024.e28016_bib26","doi-asserted-by":"crossref","first-page":"4440","DOI":"10.1111\/bph.12795","article-title":"Quercetin attenuates doxorubicin cardiotoxicity by modulating B mi\u20101 expression","volume":"171","author":"Dong","year":"2014","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.heliyon.2024.e28016_bib27","doi-asserted-by":"crossref","first-page":"84","DOI":"10.4103\/0973-7847.194044","article-title":"Overviews of biological importance of quercetin: a bioactive flavonoid","volume":"10","author":"David","year":"2016","journal-title":"Pharmacogn Rev"},{"key":"10.1016\/j.heliyon.2024.e28016_bib28","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1007\/s11064-018-2576-x","article-title":"Identification of proteins differentially expressed by quercetin treatment in a middle cerebral artery occlusion model: a proteomics approach","volume":"43","author":"Shah","year":"2018","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.heliyon.2024.e28016_bib29","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.3390\/ph16081182","article-title":"Quercetin alleviated inflammasome-mediated pyroptosis and modulated the mTOR\/P70S6\/P6\/eIF4E\/4EBP1 pathway in ischemic stroke","volume":"16","author":"Alattar","year":"2023","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.heliyon.2024.e28016_bib30","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1292\/jvms.14-0169","article-title":"Proteomic identification of proteins differentially expressed in response to resveratrol treatment in middle cerebral artery occlusion stroke model","volume":"76","author":"Shah","year":"2014","journal-title":"J. Vet. Med. Sci."},{"key":"10.1016\/j.heliyon.2024.e28016_bib31","doi-asserted-by":"crossref","first-page":"659","DOI":"10.3389\/fnins.2020.00659","article-title":"Potent natural antioxidant carveol attenuates MCAO-stress induced oxidative, neurodegeneration by regulating the Nrf-2 pathway","volume":"14","author":"Malik","year":"2020","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.heliyon.2024.e28016_bib32","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1042\/BJ20111351","article-title":"\u03b3-Enolase C-terminal peptide promotes cell survival and neurite outgrowth by activation of the PI3K\/Akt and MAPK\/ERK signalling pathways","volume":"443","author":"Hafner","year":"2012","journal-title":"Biochem. J."},{"key":"10.1016\/j.heliyon.2024.e28016_bib33","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1038\/nn936","article-title":"NMDA receptor pathways as drug targets","volume":"5","author":"Kemp","year":"2002","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.heliyon.2024.e28016_bib34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0004764","article-title":"Identification of ischemic regions in a rat model of stroke","volume":"4","author":"Popp","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.heliyon.2024.e28016_bib35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.pneurobio.2016.06.001","article-title":"Calpains and neuronal damage in the ischemic brain: the swiss knife in synaptic injury","volume":"143","author":"Curcio","year":"2016","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.heliyon.2024.e28016_bib36","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0166-2236(99)01401-0","article-title":"Pathobiology of ischaemic stroke: an integrated view","volume":"22","author":"Dirnagl","year":"1999","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.heliyon.2024.e28016_bib37","doi-asserted-by":"crossref","first-page":"10581","DOI":"10.1073\/pnas.1202810109","article-title":"Small molecule-induced cytosolic activation of protein kinase Akt rescues ischemia-elicited neuronal death","volume":"109","author":"Jo","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.heliyon.2024.e28016_bib38","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1038\/25147","article-title":"Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway","volume":"396","author":"Yano","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.heliyon.2024.e28016_bib39","doi-asserted-by":"crossref","first-page":"26596","DOI":"10.1074\/jbc.273.41.26596","article-title":"N-Methyl-D-aspartate inhibits apoptosis through activation of phosphatidylinositol 3-kinase in cerebellar granule neurons: a role for insulin receptor substrate-1 in the neurotrophic action of n-methyl-D-aspartate and its inhibition by ethanol","volume":"273","author":"Zhang","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.heliyon.2024.e28016_bib40","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1038\/sj.jcbfm.9600303","article-title":"Activation of the Akt\/GSK3\u03b2 signaling pathway mediates survival of vulnerable hippocampal neurons after transient global cerebral ischemia in rats","volume":"26","author":"Endo","year":"2006","journal-title":"J. Cerebr. Blood Flow Metabol."},{"key":"10.1016\/j.heliyon.2024.e28016_bib41","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1097\/00004647-200112000-00009","article-title":"Evidence of phosphorylation of Akt and neuronal survival after transient focal cerebral ischemia in mice","volume":"21","author":"Noshita","year":"2001","journal-title":"J. Cerebr. Blood Flow Metabol."},{"key":"10.1016\/j.heliyon.2024.e28016_bib42","first-page":"748","article-title":"Effect of different charges of modified electroconvulsive seizure on the cognitive behavior in stressed rats: effects of GluR1 phosphorylation and CaMKII\u03b1 activity","volume":"17","author":"Zhang","year":"2019","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.heliyon.2024.e28016_bib43","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.ejphar.2007.09.028","article-title":"Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus","volume":"578","author":"Matsuzaki","year":"2008","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.heliyon.2024.e28016_bib44","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1038\/35016089","article-title":"Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity","volume":"405","author":"Lee","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.heliyon.2024.e28016_bib45","first-page":"269","article-title":"AMPA receptor trafficking and learning","volume":"32","author":"Keifer","year":"2010","journal-title":"J. Physiol."},{"key":"10.1016\/j.heliyon.2024.e28016_bib46","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/S0092-8674(03)00122-3","article-title":"Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory","volume":"112","author":"Lee","year":"2003","journal-title":"Cell"},{"key":"10.1016\/j.heliyon.2024.e28016_bib47","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1073\/pnas.022575999","article-title":"Synaptophysin regulates activity-dependent synapse formation in cultured hippocampal neurons","volume":"99","author":"Tarsa","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.heliyon.2024.e28016_bib48","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/0166-2236(94)90140-6","article-title":"Anoxic LTP sheds light on the multiple facets of NMDA receptors","volume":"17","author":"Hammond","year":"1994","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.heliyon.2024.e28016_bib49","doi-asserted-by":"crossref","first-page":"3108","DOI":"10.1523\/JNEUROSCI.22-08-03108.2002","article-title":"Remodeling of hippocampal synaptic networks by a brief anoxia\u2013hypoglycemia","volume":"22","author":"Jourdain","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.heliyon.2024.e28016_bib50","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1046\/j.1460-9568.2002.02141.x","article-title":"Lack of PSD\u201095 drives hippocampal neuronal cell death through activation of an \u03b1CaMKII transduction pathway","volume":"16","author":"Gardoni","year":"2002","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.heliyon.2024.e28016_bib51","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.jns.2013.04.023","article-title":"Postsynaptic density protein (PSD)-95 expression is markedly decreased in the hippocampal CA1 region after experimental ischemia\u2013reperfusion injury","volume":"330","author":"Yan","year":"2013","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.heliyon.2024.e28016_bib52","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1111\/jpi.12114","volume":"56","author":"Juan","year":"2014","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.heliyon.2024.e28016_bib53","doi-asserted-by":"crossref","first-page":"21","DOI":"10.4331\/wjbc.v8.i1.21","article-title":"Biochemical changes in the injured brain","volume":"8","author":"Sahu","year":"2017","journal-title":"World J. Biol. Chem."},{"key":"10.1016\/j.heliyon.2024.e28016_bib54","doi-asserted-by":"crossref","first-page":"254","DOI":"10.20517\/2347-8659.2017.59","article-title":"Neuron specific enolase is a potential target for regulating neuronal cell survival and death: implications in neurodegeneration and regeneration","volume":"4","author":"Polcyn","year":"2017","journal-title":"Neuroimmunol. Neuroinflammation"},{"key":"10.1016\/j.heliyon.2024.e28016_bib55","doi-asserted-by":"crossref","first-page":"198","DOI":"10.5625\/lar.2015.31.4.198","article-title":"Curcumin attenuates the middle cerebral artery occlusion-induced reduction in \u03b3-enolase expression in an animal model","volume":"31","author":"Gim","year":"2015","journal-title":"Lab Anim Res"},{"key":"10.1016\/j.heliyon.2024.e28016_bib56","doi-asserted-by":"crossref","first-page":"308","DOI":"10.5625\/lar.2017.33.4.308","article-title":"Quercetin attenuates the injury-induced reduction of \u03b3-enolase expression in a middle cerebral artery occlusion animal model","volume":"33","author":"Jeon","year":"2017","journal-title":"Lab Anim Res"},{"key":"10.1016\/j.heliyon.2024.e28016_bib57","first-page":"676","article-title":"Quercetin attenuates neuronal cells damage in a middle cerebral artery occlusion animal model","volume":"80","author":"Park","year":"2018","journal-title":"Lab Anim Res"},{"key":"10.1016\/j.heliyon.2024.e28016_bib58","doi-asserted-by":"crossref","first-page":"6736","DOI":"10.1007\/s12035-019-1568-4","article-title":"Dysregulation of CRMP2 post-translational modifications drive its pathological functions","volume":"56","author":"Moutal","year":"2019","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.heliyon.2024.e28016_bib59","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1385\/MN:28:1:51","article-title":"Collapsin response mediator proteins (CRMPs) involvement in nervous system development and adult neurodegenerative disorders","volume":"28","author":"Charrier","year":"2003","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.heliyon.2024.e28016_bib60","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/gtc.12651","article-title":"Genetic suppression of collapsin response mediator protein 2 phosphorylation improves outcome in methyl\u20104\u2010phenyl\u20101, 2, 3, 6\u2010tetrahydropyridine\u2010induced Parkinson's model mice","volume":"24","author":"Togashi","year":"2019","journal-title":"Gene Cell."},{"key":"10.1016\/j.heliyon.2024.e28016_bib61","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.neuroscience.2018.02.002","article-title":"Extracellular application of CRMP2 increases cytoplasmic calcium through NMDA receptors","volume":"376","author":"Castillo","year":"2018","journal-title":"Neuroscience"},{"key":"10.1016\/j.heliyon.2024.e28016_bib62","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/cne.20465","article-title":"Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain","volume":"486","author":"Bretin","year":"2005","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.heliyon.2024.e28016_bib63","doi-asserted-by":"crossref","first-page":"52","DOI":"10.4161\/chan.18919","article-title":"Disruption of NMDAR\u2013CRMP-2 signaling protects against focal cerebral ischemic damage in the rat middle cerebral artery occlusion model","volume":"6","author":"Brittain","year":"2012","journal-title":"Channels"},{"key":"10.1016\/j.heliyon.2024.e28016_bib64","doi-asserted-by":"crossref","DOI":"10.1615\/CritRevNeurobiol.v18.i1-2.150","article-title":"Inflammation in ischemic brain injury: timing is important","volume":"18","author":"Kriz","year":"2006","journal-title":"Crit. Rev. Neurobiol."},{"key":"10.1016\/j.heliyon.2024.e28016_bib65","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1742-2094-10-23","article-title":"Toll-like receptor 4 mediates microglial activation and production of inflammatory mediators in neonatal rat brain following hypoxia: role of TLR4 in hypoxic microglia","volume":"10","author":"Yao","year":"2013","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.heliyon.2024.e28016_bib66","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/9966663","article-title":"Carveol attenuates seizure severity and neuroinflammation in pentylenetetrazole-kindled epileptic rats by regulating the Nrf2 signaling pathway","volume":"2021","author":"Alvi","year":"2021","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.heliyon.2024.e28016_bib67","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.3389\/fphar.2020.01256","article-title":"Targeting cytokine release through the differential modulation of Nrf2 and NF-\u03baB pathways by electrophilic\/non-electrophilic compounds","volume":"11","author":"Fagiani","year":"2020","journal-title":"Front. Pharmacol."}],"updated-by":[{"DOI":"10.1016\/j.heliyon.2025.e43266","type":"retraction","label":"Retraction","source":"retraction-watch","updated":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T00:00:00Z","timestamp":1742860800000},"record-id":"66181"},{"DOI":"10.1016\/j.heliyon.2024.e28016","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T00:00:00Z","timestamp":1713139200000}},{"DOI":"10.1016\/j.heliyon.2025.e43266","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000}}],"container-title":["Heliyon"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405844024040477?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405844024040477?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T13:04:52Z","timestamp":1784207092000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405844024040477"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":67,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["S2405844024040477"],"URL":"https:\/\/doi.org\/10.1016\/j.heliyon.2024.e28016","relation":{},"ISSN":["2405-8440"],"issn-type":[{"value":"2405-8440","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"RETRACTED: Quercetin attenuated ischemic stroke induced neurodegeneration by modulating glutamatergic and synaptic signaling pathways","name":"articletitle","label":"Article Title"},{"value":"Heliyon","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.heliyon.2024.e28016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"e28016"}}