{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T21:57:42Z","timestamp":1790546262916,"version":"4.1.0"},"reference-count":65,"publisher":"Elsevier BV","issue":"17","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T00:00:00Z","timestamp":1724112000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82074549"],"award-info":[{"award-number":["82074549"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heliyon"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.heliyon.2024.e36664","type":"journal-article","created":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T05:57:14Z","timestamp":1724392634000},"page":"e36664","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Transcriptome and proteomic analysis reveal the protective mechanism of acupuncture on reproductive function in mice with asthenospermia"],"prefix":"10.1016","volume":"10","author":[{"given":"Jianheng","family":"Hao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boya","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huichao","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haijun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laixi","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.heliyon.2024.e36664_bib1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0140-6736(20)32667-2","article-title":"Male infertility","volume":"397","author":"Agarwal","year":"2021","journal-title":"Lancet."},{"key":"10.1016\/j.heliyon.2024.e36664_bib2","series-title":"WHO Laboratory Manual for the Examination and Processing of Human Semen","year":"2021"},{"key":"10.1016\/j.heliyon.2024.e36664_bib3","doi-asserted-by":"crossref","DOI":"10.1111\/and.13463","article-title":"Cellular and molecular contributing factors and treatment strategies","volume":"52","author":"Shahrokhi","year":"2020","journal-title":"Andrologia"},{"key":"10.1016\/j.heliyon.2024.e36664_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.beem.2020.101472","article-title":"Genetic underpinnings of asthenozoospermia","volume":"34","author":"Tu","year":"2020","journal-title":"Best Pract. Res. Clin. Endocrinol. Metabol."},{"key":"10.1016\/j.heliyon.2024.e36664_bib5","doi-asserted-by":"crossref","first-page":"478","DOI":"10.4103\/aja.aja_110_18","article-title":"Heavy cigarette smoking and alcohol consumption are associated with impaired sperm parameters in primary infertile men","volume":"21","author":"Boeri","year":"2019","journal-title":"Asian J. Androl."},{"key":"10.1016\/j.heliyon.2024.e36664_bib6","doi-asserted-by":"crossref","first-page":"175","DOI":"10.5534\/wjmh.180069","article-title":"Traditional Chinese medicine as a remedy for male infertility: a review","volume":"37","author":"Zhou","year":"2019","journal-title":"World. J. Mens. Health"},{"key":"10.1016\/j.heliyon.2024.e36664_bib7","doi-asserted-by":"crossref","first-page":"142","DOI":"10.56434\/j.arch.esp.urol.20247702.19","article-title":"Enhancing sperm motility parameters in patients with asthenospermia: a combined approach of acupuncture at fusiguan point and tamoxifen citrate tablets","volume":"77","author":"Luo","year":"2024","journal-title":"Arch. Esp. Urol."},{"key":"10.1016\/j.heliyon.2024.e36664_bib8","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1111\/and.12541","article-title":"Randomised clinical trial of comparing effects of acupuncture and varicocelectomy on sperm parameters in infertile varicocele patients","volume":"48","author":"Kucuk","year":"2016","journal-title":"Andrologia"},{"key":"10.1016\/j.heliyon.2024.e36664_bib9","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1089\/acu.2021.0063","article-title":"Electroacupuncture effectiveness for treating idiopathic male infertility","volume":"34","author":"Nurwati","year":"2022","journal-title":"Med. Acupunct."},{"key":"10.1016\/j.heliyon.2024.e36664_bib10","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.3889\/oamjms.2018.379","article-title":"Acupuncture treatment for fertility","volume":"6","author":"Zhu","year":"2018","journal-title":"Open Access Maced J Med Sci"},{"key":"10.1016\/j.heliyon.2024.e36664_bib11","first-page":"906","article-title":"Electroacupuncture regulates sperm motility in patients with asthenozoospermia: study protocol for a randomized sham-controlled clinical trial","volume":"114","author":"Huang","year":"2023","journal-title":"Minerva Med."},{"key":"10.1016\/j.heliyon.2024.e36664_bib12","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1136\/acupmed-2017-011365","article-title":"Effects and mechanism of action of transcutaneous electrical acupuncture point stimulation in patients with abnormal semen parameters","volume":"37","author":"Guan","year":"2019","journal-title":"Acupunct. Med."},{"key":"10.1016\/j.heliyon.2024.e36664_bib13","doi-asserted-by":"crossref","first-page":"53","DOI":"10.4161\/spmg.19282","article-title":"Electroacupuncture enhances spermatogenesis in rats after scrotal heat treatment","volume":"2","author":"Gao","year":"2012","journal-title":"Spermatogenesis"},{"key":"10.1016\/j.heliyon.2024.e36664_bib14","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1007\/s11655-018-2915-9","article-title":"Effect of electroacupuncture on spermatogenesis in rats with oligozoospermia of insufficiency of shen (kidney) essence syndrome","volume":"25","author":"Cui","year":"2019","journal-title":"Chin. J. Integr. Med."},{"key":"10.1016\/j.heliyon.2024.e36664_bib15","first-page":"114","article-title":"Experimental study on electroacupuncture for asthenozoospermia in rats","volume":"42","author":"Jin","year":"2017","journal-title":"Acupunct. Res."},{"key":"10.1016\/j.heliyon.2024.e36664_bib16","first-page":"537","article-title":"Effect of \"Zhibian\" (BL 54)-to-\"Shuidao\" (ST 28) needle insertion on the expression of Fas\/FADD\/Caspase-8 of death receptor pathway in rats with primary ovarian insufficiency","volume":"43","author":"Yan","year":"2023","journal-title":"Chin. Acupunct. Moxibustion"},{"key":"10.1016\/j.heliyon.2024.e36664_bib17","first-page":"461","article-title":"Observation on the therapeutic effect of \" Zhibian\"(BL 54)-to-\"Shuidao\" (ST 28) on polycystic ovary syndrome","volume":"35","author":"Hao","year":"2015","journal-title":"Chin. Acupunct. Moxibustion"},{"key":"10.1016\/j.heliyon.2024.e36664_bib18","first-page":"1266","article-title":"Cao Y.X. Ji J.Q. Xu N.H. Ji L.X. Clinical observation on the treatment of primary dysmenorrhea patients with the \"Zhibian\" (BL 54)-to-\"Shuidao\" (ST 28) acupuncture method","volume":"39","author":"Wang","year":"2019","journal-title":"Chin. J. Integr. Tradit. West. Med."},{"key":"10.1016\/j.heliyon.2024.e36664_bib19","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/978-1-4939-7717-8_2","article-title":"Cai L. Transcriptome sequencing: RNA-seq","volume":"1754","author":"Zhang","year":"2018","journal-title":"Comp Syst Biol"},{"key":"10.1016\/j.heliyon.2024.e36664_bib20","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1021\/acs.jproteome.1c00686","article-title":"Collision cross sections for native proteomics: challenges and opportunities","volume":"21","author":"Ruotolo","year":"2021","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.heliyon.2024.e36664_bib21","article-title":"C-type natriuretic peptide (cnp) could improve sperm motility and reproductive function of asthenozoospermia","volume":"23","author":"Li","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.heliyon.2024.e36664_bib22","first-page":"86","article-title":"Effect of\u201cZhibian (BL 54)-to-Shuidao (ST 28)\u201d acupuncture stimulation on key factors of apoptotic pathways inside and outside the testes in mice with asthenozoospermia","volume":"65","author":"Hao","year":"2024","journal-title":"J. Tradit. Chin. Med."},{"key":"10.1016\/j.heliyon.2024.e36664_bib23","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1016\/j.cub.2020.09.068","article-title":"Ferroptosis","volume":"30","author":"Tang","year":"2020","journal-title":"Curr. Biol."},{"key":"10.1016\/j.heliyon.2024.e36664_bib24","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202300756R","article-title":"Research progress on ion channels and their molecular regulatory mechanisms in the human sperm flagellum","volume":"37","author":"Cong","year":"2023","journal-title":"Faseb. J."},{"key":"10.1016\/j.heliyon.2024.e36664_bib25","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1007\/s00280-016-3152-1","article-title":"The effect of cyclophosphamide on the immune system: implications for clinical cancer therapy","volume":"78","author":"Ahlmann","year":"2016","journal-title":"Cancer Chemother. Pharmacol."},{"key":"10.1016\/j.heliyon.2024.e36664_bib26","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1111\/jcmm.16263","article-title":"Identification of abnormal protein expressions associated with mouse spermatogenesis induced by cyclophosphamide","volume":"25","author":"Liu","year":"2021","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.heliyon.2024.e36664_bib27","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1007\/s10815-023-02870-4","article-title":"Prediction of microdissection testicular sperm extraction outcomes of azoospermic patients post-chemotherapy using cyclophosphamide equivalent dose","volume":"40","author":"Tsai","year":"2023","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.heliyon.2024.e36664_bib28","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1007\/s43032-020-00357-6","article-title":"Histologic analysis of testes from prepubertal patients treated with chemotherapy associates impaired germ cell counts with cumulative doses of cyclophosphamide, ifosfamide, cytarabine, and asparaginase","volume":"28","author":"Medrano","year":"2021","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.heliyon.2024.e36664_bib29","doi-asserted-by":"crossref","DOI":"10.1111\/and.14071","article-title":"Cyclophosphamide suppresses spermatogenesis in the testis of mice through downregulation of miR\u201034b and miR\u201034c","volume":"53","author":"\u00d6zbilgin","year":"2021","journal-title":"Andrologia"},{"key":"10.1016\/j.heliyon.2024.e36664_bib30","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1080\/17425255.2017.1277205","article-title":"The mechanisms of cyclophosphamide-induced testicular toxicity and the protective agents","volume":"13","author":"Ghobadi","year":"2017","journal-title":"Expert. Opin. Drug. Metab."},{"key":"10.1016\/j.heliyon.2024.e36664_bib31","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1210\/endocr\/bqaa120","article-title":"Testosterone, spermatogenesis, and unravelling the mysteries of puberty","volume":"161","author":"Handelsman","year":"2020","journal-title":"Endocrinology"},{"key":"10.1016\/j.heliyon.2024.e36664_bib32","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.3390\/jcm9041014","article-title":"Follicle-stimulating hormone (FSH) action on spermatogenesis: a focus on physiological and therapeutic roles","volume":"9","author":"Santi","year":"2020","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.heliyon.2024.e36664_bib33","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1177\/1933719116641766","article-title":"Modulation of human sperm capacitation by progesterone, estradiol, and luteinizing hormone","volume":"24","author":"L\u00f3pez-Torres","year":"2017","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.heliyon.2024.e36664_bib34","doi-asserted-by":"crossref","DOI":"10.1080\/21565562.2014.996025","article-title":"Endocrine control of spermatogenesis: role of FSH and LH\/testosterone","volume":"4","author":"Ramaswamy","year":"2014","journal-title":"Spermatogenesis"},{"key":"10.1016\/j.heliyon.2024.e36664_bib35","first-page":"285","article-title":"The effect of leaf hydroalcoholic extract of Ephedra pachyclada infertility in male rats treated with cyclophosphamide: an experimental study","volume":"21","author":"Saleh","year":"2023","journal-title":"Int. J. Reprod. Biomed."},{"key":"10.1016\/j.heliyon.2024.e36664_bib36","doi-asserted-by":"crossref","DOI":"10.1111\/and.13463","article-title":"Cellular and molecular contributing factors and treatment strategies","volume":"52","author":"Shahrokhi","year":"2020","journal-title":"Andrologia"},{"key":"10.1016\/j.heliyon.2024.e36664_bib37","doi-asserted-by":"crossref","first-page":"122","DOI":"10.53388\/psmr2021-0920-047","article-title":"Discussion on treatment of asthenospermia from the perspective of psychosomatic medicine of traditional Chinese medicine","volume":"3","author":"Jiang","year":"2021","journal-title":"Psychosom. Med. Res."},{"key":"10.1016\/j.heliyon.2024.e36664_bib38","first-page":"493","article-title":"Role of sperm apoptosis and oxidative stress in male infertility: a narrative review","volume":"19","author":"Asadi","year":"2021","journal-title":"Int. J. Reprod. Biomed."},{"key":"10.1016\/j.heliyon.2024.e36664_bib39","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1590\/1806-9282.20210634","article-title":"Effect of Lactobacillus species on apoptosis-related genes BCL2, BAX, and caspase 3 in the testes of gamma-irradiated rats","volume":"67","author":"Changizi","year":"2021","journal-title":"Rev. Assoc. Med. Bras."},{"key":"10.1016\/j.heliyon.2024.e36664_bib40","article-title":"Qiangjing tablets regulate apoptosis and oxidative stress via Keap\/Nrf2 pathway to improve the reproductive function in asthenospermia rats","volume":"12","author":"Li","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.heliyon.2024.e36664_bib41","doi-asserted-by":"crossref","first-page":"3106","DOI":"10.1038\/s41598-023-29775-7","article-title":"GRIM-19 in asthenozoospermia regulates GC-2 spd cell proliferation, apoptosis and migration","volume":"13","author":"Li","year":"2023","journal-title":"Sci. Rep."},{"key":"10.1016\/j.heliyon.2024.e36664_bib42","doi-asserted-by":"crossref","first-page":"5268","DOI":"10.3390\/nu14245268","article-title":"Review of the role of ferroptosis in testicular function","volume":"14","author":"Yang","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.heliyon.2024.e36664_bib43","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1038\/s41420-023-01665-x","article-title":"Emerging roles of ferroptosis in male reproductive diseases","volume":"9","author":"Yuan","year":"2023","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.heliyon.2024.e36664_bib44","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3390\/genes14010043","article-title":"Ferroptosis: a novel type of cell death in male reproduction","volume":"14","author":"Su","year":"2022","journal-title":"Genes"},{"key":"10.1016\/j.heliyon.2024.e36664_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.162089","article-title":"PM2. 5 caused ferroptosis in spermatocyte via overloading iron and disrupting redox homeostasis","volume":"872","author":"Wang","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.heliyon.2024.e36664_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.121434","article-title":"Cadmium exposure during puberty damages testicular development and spermatogenesis via ferroptosis caused by intracellular iron overload and oxidative stress in mice","volume":"325","author":"Wang","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.heliyon.2024.e36664_bib47","doi-asserted-by":"crossref","first-page":"134","DOI":"10.3390\/antiox9020134","article-title":"Molecular changes induced by oxidative stress that impair human sperm motility","volume":"9","author":"Nowicka-Bauer","year":"2020","journal-title":"Antioxidants"},{"key":"10.1016\/j.heliyon.2024.e36664_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.110360","article-title":"Arsenite induces testicular oxidative stress in vivo and in vitro leading to ferroptosis","volume":"194","author":"Meng","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.heliyon.2024.e36664_bib49","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1038\/s41419-023-06359-x","article-title":"Gss deficiency causes age-related fertility impairment via ROS-triggered ferroptosis in the testes of mice","volume":"14","author":"Zhu","year":"2023","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.heliyon.2024.e36664_bib50","doi-asserted-by":"crossref","first-page":"375","DOI":"10.4103\/aja202266","article-title":"Bisphenol A induces testicular oxidative stress in mice leading to ferroptosis","volume":"25","author":"Li","year":"2023","journal-title":"Asian J. Androl."},{"key":"10.1016\/j.heliyon.2024.e36664_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejcb.2019.151058","article-title":"Mitochondria regulation in ferroptosis","volume":"99","author":"Wang","year":"2020","journal-title":"Eur. J. Cell Biol."},{"key":"10.1016\/j.heliyon.2024.e36664_bib52","doi-asserted-by":"crossref","first-page":"363","DOI":"10.3390\/jcm9020363","article-title":"Evaluation of sperm mitochondrial function: a key organelle for sperm motility","volume":"9","author":"Barbagallo","year":"2020","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.heliyon.2024.e36664_bib53","doi-asserted-by":"crossref","first-page":"184","DOI":"10.3390\/biology10030184","article-title":"Lipid metabolism and ferroptosis","volume":"10","author":"Lee","year":"2021","journal-title":"Biology"},{"key":"10.1016\/j.heliyon.2024.e36664_bib54","doi-asserted-by":"crossref","first-page":"2244","DOI":"10.1038\/s41467-021-22471-y","article-title":"Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1","volume":"12","author":"Beatty","year":"2021","journal-title":"Nat. Commun."},{"issue":"12","key":"10.1016\/j.heliyon.2024.e36664_bib55","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.3390\/v13122383","article-title":"Inhibiting ACSL1-related ferroptosis restrains murine coronavirus infection","volume":"13","author":"Xia","year":"2021","journal-title":"Viruses"},{"key":"10.1016\/j.heliyon.2024.e36664_bib56","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2020.586578","article-title":"Oxidative damage and antioxidant defense in ferroptosis","volume":"8","author":"Kuang","year":"2020","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.heliyon.2024.e36664_bib57","doi-asserted-by":"crossref","first-page":"7706","DOI":"10.3390\/ijms24097706","article-title":"Nadph oxidase subunit cybb confers chemotherapy and ferroptosis resistance in mesenchymal glioblastoma via nrf2\/sod2 modulation","volume":"24","author":"Su","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.heliyon.2024.e36664_bib58","doi-asserted-by":"crossref","first-page":"308","DOI":"10.3389\/fnagi.2016.00308","article-title":"The protective role of mitochondrial ferritin on erastin-induced ferroptosis","volume":"8","author":"Wang","year":"2016","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.heliyon.2024.e36664_bib59","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.3390\/cells10081969","article-title":"Mitochondrial ferritin: its role in physiological and pathological conditions","volume":"10","author":"Levi","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.heliyon.2024.e36664_bib60","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1089\/ars.2019.7905","article-title":"Regulatory phenomena in the glutathione peroxidase superfamily","volume":"33","author":"Brigelius-Floh\u00e9","year":"2020","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.heliyon.2024.e36664_bib61","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1002\/jat.4273","article-title":"The effects of selenium on GPX4-mediated lipid peroxidation and apoptosis in germ cells","volume":"42","author":"Liu","year":"2022","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.heliyon.2024.e36664_bib62","doi-asserted-by":"crossref","first-page":"2621","DOI":"10.1080\/15548627.2023.2218764","article-title":"GPX4 in cell death, autophagy, and disease","volume":"19","author":"Xie","year":"2023","journal-title":"Autophagy"},{"key":"10.1016\/j.heliyon.2024.e36664_bib63","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s43032-022-01004-y","article-title":"Reduction of SLC7A11 and GPX4 contributing to ferroptosis in sperm from asthenozoospermia individuals","volume":"30","author":"Hao","year":"2023","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.heliyon.2024.e36664_bib64","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1080\/13880209.2023.2165114","article-title":"Guilu-Erxian-Glue alleviates Tripterygium wilfordii polyglycoside-induced oligoasthenospermia in rats by resisting ferroptosis via the Keap1\/Nrf2\/GPX4 signaling pathway","volume":"61","author":"Ding","year":"2023","journal-title":"Pharm. Biol."},{"key":"10.1016\/j.heliyon.2024.e36664_bib65","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/tox.23713","article-title":"Bone marrow mesenchymal stem cells repair hexavalent chromium-induced testicular injury by regulating autophagy and ferroptosis mediated by the AKT\/mTOR pathway in rats","volume":"38","author":"Zhuge","year":"2023","journal-title":"Environ. Toxicol."}],"container-title":["Heliyon"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405844024126953?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405844024126953?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T21:20:40Z","timestamp":1790544040000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405844024126953"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":65,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S2405844024126953"],"URL":"https:\/\/doi.org\/10.1016\/j.heliyon.2024.e36664","relation":{},"ISSN":["2405-8440"],"issn-type":[{"value":"2405-8440","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transcriptome and proteomic analysis reveal the protective mechanism of acupuncture on reproductive function in mice with asthenospermia","name":"articletitle","label":"Article Title"},{"value":"Heliyon","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.heliyon.2024.e36664","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"e36664"}}