{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:38:07Z","timestamp":1786653487110,"version":"build-2736575974"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,8,20]],"date-time":"2013-08-20T00:00:00Z","timestamp":1376956800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>The risk associated with arterial thromboembolism (ATE) increases with the presence of anti-vascular endothelial growth factor (VEGF). We are reporting a case of transient ischemic attack (TIA) due to stenosis of the carotid and brachiocephalic arteries following long-term treatment with sorafenib for renal cell carcinoma (RCC). The patient is a non-smoker with no known comorbidities and had no history of cardiovascular disease. The patient underwent a right endarterectomy with angioplasty, aortic arch, and brachiocephalic artery angiogram with a stent placed in the brachiocephalic artery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.hemonc.2013.06.005","type":"journal-article","created":{"date-parts":[[2013,7,24]],"date-time":"2013-07-24T06:38:15Z","timestamp":1374647895000},"page":"53-55","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Carotid and brachiocephalic arteries stenosis with long term use of sorafenib"],"prefix":"10.4103","volume":"7","author":[{"given":"Fatma","family":"Maraiki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Aljubran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"10.1016\/j.hemonc.2013.06.005_b0005","unstructured":"Sorafenib sorafenib and carotid artery stenosis. (http:\/\/www.drugcite.com\/) http:\/\/www.drugcite.com\/indi\/?q=SORAFENIB%20SORAFENIB&s=&a=&i=CAROTID+ARTERY+STENOSIS#showRxAdverseEvents. (last accessed 15 Jun 2013)."},{"issue":"3","key":"10.1016\/j.hemonc.2013.06.005_b0010","doi-asserted-by":"crossref","first-page":"287","DOI":"10.3109\/02841860903524396","article-title":"Risk of cardiac ischemia and arterial thromboembolism events with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysis of randomized controlled trials","volume":"49","author":"Ranpura","year":"2010","journal-title":"Acta Oncol"},{"issue":"13","key":"10.1016\/j.hemonc.2013.06.005_b0015","doi-asserted-by":"crossref","first-page":"2280","DOI":"10.1200\/JCO.2009.27.2757","article-title":"Risk of arterial thromboembolism events with sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials","volume":"28","author":"Choueiri","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.hemonc.2013.06.005_b0020","first-page":"616080","article-title":"Cerebrovascular accidents associated with sorafenib in hepatocellular carcinoma","volume":"2","author":"Saif","year":"2011","journal-title":"Gastroenterol Res Pract"},{"key":"10.1016\/j.hemonc.2013.06.005_b0025","unstructured":"Winnik S, Lohmann C, Siciliani G, et al. Systemic VEGF inhibition accelerates experimental atherosclerosis and disrupts endothelial homeostasis \u2013 implications for cardiovascular safety. [Published online ahead of print April 2 2013] Int J Cardiol. Pii:S0167-5273(13)00428-2. (last accessed 15 Jun 2013)."},{"issue":"4","key":"10.1016\/j.hemonc.2013.06.005_b0030","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1158\/1078-0432.CCR-08-1141","article-title":"Hand-foot skin reaction increases with cumulative sorafenib dose and with combination anti-vascular endothelial growth factor therapy","volume":"15","author":"Azad","year":"2009","journal-title":"Clin Cancer Res"}],"container-title":["Hematology\/Oncology and Stem Cell Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1658387613000654?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1658387613000654?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ovid.com\/02275670-201407010-00008","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:38:15Z","timestamp":1786649895000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/02275670-201407010-00008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1016\/j.hemonc.2013.06.005","relation":{},"ISSN":["1658-3876"],"issn-type":[{"value":"1658-3876","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]}}}