{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:35:40Z","timestamp":1787841340893,"version":"build-2784847793"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,3,21]],"date-time":"2017-03-21T00:00:00Z","timestamp":1490054400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Waldenstr\u00f6m\u2019s macroglobulinemia is a rare hematology malignancy which often presents with \u201cB symptoms,\u201d anemia, and thrombocytopenia. A 46-year-old woman presented with 2 months of abdominal distension accompanied by an unintentional 20-lb weight loss. Her abdominal CT scan demonstrated diffuse carcinomatosis with bilateral ovarian lesions and screening labs revealed a markedly elevated CA-125, suggesting a diagnosis of ovarian cancer. Upon admission for workup, patient was found to have a significant protein gap, later attributed to a markedly elevated IgM. Omental and bone marrow biopsy confirmed the diagnosis of Waldenstr\u00f6m\u2019s macroglobulinemia, with elevation in CA-125 thought to be secondary to peritoneal irritation. This patient has since been successfully treated with six cycles of bendamusine and rituximab with no evidence of disease on staging scans and normalization of both CA-125 and IgM. To our knowledge, this is the first documented case of Waldenstr\u00f6m\u2019s macroglobulinemia presenting with symptoms classically associated with ovarian cancer and demonstrates the importance of maintaining a broad differential when evaluating patients with abdominal carcinomatosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.hemonc.2017.02.004","type":"journal-article","created":{"date-parts":[[2017,3,31]],"date-time":"2017-03-31T01:02:20Z","timestamp":1490922140000},"page":"54-59","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Waldenstr\u00f6m\u2019s macroglobulinemia masquerading as ovarian cancer with peritoneal carcinomatosis, ascites, and elevated CA-125"],"prefix":"10.4103","volume":"12","author":[{"given":"Patrick","family":"Eulitt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise","family":"Fabian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Crystal","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Hemminger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basem M.","family":"William","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"10.1016\/j.hemonc.2017.02.004_b0005","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1111\/j.1365-2141.2007.06724.x","article-title":"Waldenstr\u00f6m macroglobulinaemia","volume":"138","author":"Fonseca","year":"2007","journal-title":"Br J Haematol"},{"key":"10.1016\/j.hemonc.2017.02.004_b0010","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1046\/j.1365-2141.2001.03144.x","article-title":"Waldenstrom macroglobulinaemia: presenting features and outcome in a series with 217 cases","volume":"115","author":"Garcia-Sanz","year":"2001","journal-title":"Br J Haematol"},{"key":"10.1016\/j.hemonc.2017.02.004_b0015","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.gyobfe.2010.10.018","article-title":"Int\u00e9r\u00eat du dosage du CA 125dans la prise en charge du cancer de l\u2019ovaire","volume":"39","author":"Coussy","year":"2011","journal-title":"Gyn\u00e9col Obst\u00e9t Fertil"},{"key":"10.1016\/j.hemonc.2017.02.004_b0020","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1007\/s10552-010-9525-6","article-title":"Primary peritoneal and ovarian cancers: an epidemiological comparative analysis","volume":"21","author":"Grant","year":"2010","journal-title":"Cancer Causes Control"},{"key":"10.1016\/j.hemonc.2017.02.004_b0025","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1002\/1097-0142(20001115)89:10<2068::AID-CNCR6>3.0.CO;2-Z","article-title":"Ovarian carcinoma diagnosis","volume":"89","author":"Goff","year":"2000","journal-title":"Cancer"},{"key":"10.1016\/j.hemonc.2017.02.004_b0030","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1097\/00006250-200108000-00006","article-title":"Symptoms of ovarian cancer","volume":"98","author":"Olson","year":"2001","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.hemonc.2017.02.004_b0035","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1002\/cncr.23577","article-title":"Combining a symptoms index with CA 125 to improve detection of ovarian cancer","volume":"113","author":"Andersen","year":"2008","journal-title":"Cancer"},{"key":"10.1016\/j.hemonc.2017.02.004_b0040","unstructured":"American College of Obstetricians and Gynecologists. 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