{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:35:18Z","timestamp":1787841318761,"version":"build-2784847793"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,3,17]],"date-time":"2020-03-17T00:00:00Z","timestamp":1584403200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Here we describe a rare case of renal myeloid sarcoma, first discovered incidentally on routine urine analysis, which is one of the first of it\u2019s kind to be reported. We describe the vanishingly rare phenomenon of renal myeloid sarcoma presenting without haematological manifestation while also highlighting the often inevitable transformative nature of the disease. We also describe the unusual immunohistochemistry findings, in particular the cytokeratin expression, that is not usually typical of such cases. We briefly discuss use of PET-CT for the disease response monitoring. We summarize treatment that has included palbociclib, use of which was previously reported only in small series of patients with AML with KMT2A mutation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.hemonc.2020.02.007","type":"journal-article","created":{"date-parts":[[2020,3,18]],"date-time":"2020-03-18T12:43:18Z","timestamp":1584535398000},"page":"343-347","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["The first case of acute myeloid leukaemia\/myeloid sarcoma with cytokeratin expression on blasts diagnosed on urine specimen"],"prefix":"10.4103","volume":"14","author":[{"given":"Claire","family":"Comerford","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah Ni","family":"Mhaolcatha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Hayes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vitaliy","family":"Mykytiv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-9-20241211","doi-asserted-by":"crossref","first-page":"2697","DOI":"10.1002\/1097-0142(19861215)58:12<2697::AID-CNCR2820581225>3.0.CO;2-R","article-title":"Granulocytic sarcoma in nonleukemic patients","volume":"58","author":"Meis","year":"1986","journal-title":"Cancer"},{"key":"R5-9-20241211","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1016\/S0022-5347(17)32318-2","article-title":"Granulocytic sarcoma presenting as a diffuse renal mass before hematological manifestations of acute myelogenous leukemia","volume":"152","author":"Bagg","year":"1994","journal-title":"J Urol"},{"key":"R6-9-20241211","doi-asserted-by":"crossref","first-page":"740","DOI":"10.3349\/ymj.2003.44.4.740","article-title":"Myeloid sarcoma of both kidneys, the brain, and multiple bones in a nonleukemic child","volume":"44","author":"Park","year":"2003","journal-title":"Yonsei Med J"},{"key":"R7-9-20241211","first-page":"55","article-title":"Myeloid sarcoma of the kidney preceding acute myeloid leukemia","volume":"16","author":"Awamleh","year":"2009","journal-title":"JRMS"},{"key":"R8-9-20241211","first-page":"861232","article-title":"Nonleukemic ureteral granulocytic sarcoma presenting with unilateral urinary obstruction and hematuria","volume":"2013","author":"Acar","year":"2013","journal-title":"Case Rep Urol"},{"key":"R10-9-20241211","doi-asserted-by":"crossref","first-page":"606","DOI":"10.4103\/0377-4929.85111","article-title":"Nonleukemic granulocytic sarcoma of kidney with mixed phenotype blasts: a diagnostic dilemma","volume":"54","author":"Agrawal","year":"2011","journal-title":"Indian J Pathol Microbiol"},{"key":"R11-9-20241211","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/0090-4295(86)90288-8","article-title":"Acute obstructive renal failure secondary to granulocytic sarcoma (chloroma)","volume":"27","author":"Steinbock","year":"1986","journal-title":"Urology"},{"key":"R12-9-20241211","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1002\/1097-0142(197304)31:4<948::AID-CNCR2820310428>3.0.CO;2-N","article-title":"Autopsy study of granulocytic sarcoma (chloroma) in patients with myelogenous leukemia, Hiroshima-Nagasaki 1949\u20131969","volume":"31","author":"Liu","year":"1973","journal-title":"Cancer"},{"key":"R13-9-20241211","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1182\/blood-2016-04-712109","article-title":"Cytokeratin-type intermediate filaments in a gastric myeloid sarcoma: a diagnostic pitfall","volume":"128","author":"Schmitt-Graeff","year":"2016","journal-title":"Blood"},{"key":"R14-9-20241211","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1080\/003130200104312","article-title":"A case of keratin-positive acute myeloid leukemia: a possible role for cytokeratin 19 as a specific epithelial marker","volume":"32","author":"Turner","year":"2000","journal-title":"Pathology"},{"key":"R15-9-20241211","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1136\/jcp.54.9.735","article-title":"Cytokeratin expression by CD34 positive blasts in a case of refractory anaemia with excess of blasts in transformation (RAEB-t)","volume":"54","author":"Dargent","year":"2001","journal-title":"J Clin Pathol"},{"key":"R16-9-20241211","first-page":"364","article-title":"Fine-needle aspiration biopsy of granulocytic sarcoma: a clinicopathologic study of 27 cases","volume":"90","author":"Suh","year":"2000","journal-title":"J Clin Pathol"},{"key":"R17-9-20241211","first-page":"520","article-title":"Ki-1-positive large cell anaplastic lymphoma diagnosed by urinary cytology","volume":"37","author":"Tanaka","year":"1993","journal-title":"A case report. 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