{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:36:47Z","timestamp":1760488607973},"reference-count":47,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["heartfailure.theclinics.com","mdconsult.com","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart Failure Clinics"],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.1016\/j.hfc.2014.04.012","type":"journal-article","created":{"date-parts":[[2014,6,27]],"date-time":"2014-06-27T08:50:29Z","timestamp":1403859029000},"page":"503-510","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Outcomes in Patients with Heart Failure with Preserved Ejection Fraction"],"prefix":"10.1016","volume":"10","author":[{"given":"Katrina K.","family":"Poppe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert N.","family":"Doughty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.hfc.2014.04.012_bib1","doi-asserted-by":"crossref","first-page":"e28","DOI":"10.1161\/01.cir.0000441139.02102.80","article-title":"Heart disease and stroke statistics\u20142014 update: a report from the American Heart Association","volume":"129","author":"Go","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.hfc.2014.04.012_bib2","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1136\/heart.89.6.615","article-title":"Prognosis for patients newly admitted to hospital with heart failure: survival trends in 12 220 index admissions in Leicestershire 1993-2001","volume":"89","author":"Blackledge","year":"2003","journal-title":"Heart"},{"key":"10.1016\/j.hfc.2014.04.012_bib3","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.ehj.2003.12.012","article-title":"Decreasing one-year mortality and hospitalization rates for heart failure in Sweden: data from the Swedish hospital discharge registry 1988 to 2000","volume":"25","author":"Schaufelberger","year":"2004","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hfc.2014.04.012_bib4","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1001\/jama.292.3.344","article-title":"Trends in heart failure incidence and survival in a community-based population","volume":"292","author":"Roger","year":"2004","journal-title":"JAMA"},{"key":"10.1016\/j.hfc.2014.04.012_bib5","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1093\/eurheartj\/ehs104","volume":"33","author":"McMurray","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hfc.2014.04.012_bib6","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1056\/NEJMoa043399","article-title":"Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure","volume":"352","author":"Bardy","year":"2005","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.hfc.2014.04.012_bib7","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/j.jacc.2008.12.007","article-title":"Heart failure with normal left ventricular ejection fraction","volume":"53","author":"Maeder","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.hfc.2014.04.012_bib8","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S1388-9842(99)00039-2","article-title":"Perindopril for elderly people with chronic heart failure: the PEP-CHF study","volume":"1","author":"Cleland","year":"1999","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.hfc.2014.04.012_bib9","doi-asserted-by":"crossref","first-page":"2456","DOI":"10.1056\/NEJMoa0805450","article-title":"Irbesartan in patients with heart failure and preserved ejection fraction","volume":"359","author":"Massie","year":"2008","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.hfc.2014.04.012_bib10","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/S0140-6736(03)14285-7","article-title":"Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-preserved trial","volume":"362","author":"Yusuf","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.hfc.2014.04.012_bib11","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1161\/CIRCULATIONAHA.111.080770","article-title":"Trends in patients hospitalized with heart failure and preserved left ventricular ejection fraction: prevalence, therapies, and outcomes","volume":"126","author":"Steinberg","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.hfc.2014.04.012_bib12","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1056\/NEJMoa051530","article-title":"Outcome of heart failure with preserved ejection fraction in a population-based study","volume":"355","author":"Bhatia","year":"2006","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.hfc.2014.04.012_bib13","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1056\/NEJMoa052256","article-title":"Trends in prevalence and outcome of heart failure with preserved ejection fraction","volume":"355","author":"Owan","year":"2006","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.hfc.2014.04.012_bib14","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1161\/CIRCULATIONAHA.108.812172","article-title":"Long-term trends in first hospitalization for heart failure and subsequent survival between 1986 and 2003: a population study of 5.1 million people","volume":"119","author":"Jhund","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.hfc.2014.04.012_bib15","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1093\/eurheartj\/ehn541","article-title":"Survival trends in men and women with heart failure of ischaemic and non-ischaemic origin: data for the period 1987-2003 from the Swedish hospital discharge registry","volume":"30","author":"Shafazand","year":"2009","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hfc.2014.04.012_bib16","first-page":"1","article-title":"Hospitalization for congestive heart failure: United States, 2000\u20132010","volume":"108","author":"Hall","year":"2012","journal-title":"NCHS Data Brief"},{"key":"10.1016\/j.hfc.2014.04.012_bib17","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.jacc.2005.09.022","article-title":"Clinical presentation, management, and in-hospital outcomes of patients admitted with acute decompensated heart failure with preserved systolic function: a report from the Acute Decompensated Heart Failure National Registry (ADHERE) database","volume":"47","author":"Yancy","year":"2006","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.hfc.2014.04.012_bib18","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/j.jacc.2007.04.064","article-title":"Characteristics, treatments, and outcomes of patients with preserved systolic function hospitalized for heart failure: a report from the OPTIMIZE-HF registry","volume":"50","author":"Fonarow","year":"2007","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.hfc.2014.04.012_bib19","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1093\/eurjhf\/hfp103","article-title":"The prognostic significance of heart failure with preserved left ventricular ejection fraction: a literature-based meta-analysis","volume":"11","author":"Somaratne","year":"2009","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.hfc.2014.04.012_bib20","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1093\/eurheartj\/ehr254","article-title":"The survival of patients with heart failure with preserved or reduced left ventricular ejection fraction: an individual patient data meta-analysis","volume":"33","author":"Meta-analysis Global Group in Chronic Heart Failure Investigators (MAGGIC)","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hfc.2014.04.012_bib21","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1093\/eurheartj\/ehr339","article-title":"Mortality in heart failure with preserved ejection fraction: an unacceptably high rate","volume":"33","author":"Burkhoff","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hfc.2014.04.012_bib22","doi-asserted-by":"crossref","DOI":"10.1038\/ijo.2013.203","article-title":"The obesity paradox in heart failure patients with preserved versus reduced ejection fraction: a meta-analysis of individual patient data","author":"Padwal","year":"2013","journal-title":"Int J Obes"},{"key":"10.1016\/j.hfc.2014.04.012_bib23","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1093\/eurjhf\/hfs099","volume":"14","author":"Rusinaru","year":"2012","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.hfc.2014.04.012_bib24","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1093\/eurjhf\/hfs026","article-title":"Gender and survival in patients with heart failure: interactions with diabetes and aetiology. Results from the MAGGIC individual patient meta-analysis","volume":"14","author":"Martinez-Selles","year":"2012","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.hfc.2014.04.012_bib25","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1161\/CIRCHEARTFAILURE.111.966242","article-title":"Renal dysfunction in patients with heart failure with preserved versus reduced ejection fraction: impact of the new Chronic Kidney Disease-Epidemiology Collaboration Group formula","volume":"5","author":"McAlister","year":"2012","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.hfc.2014.04.012_bib26","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1093\/eurheartj\/ehs337","article-title":"Predicting survival in heart failure: a risk score based on 39 372 patients from 30 studies","volume":"34","author":"Pocock","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hfc.2014.04.012_bib27","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1111\/ejhf.32","article-title":"Predicting survival in heart failure: validation of the MAGGIC heart failure risk score in 51 043 patients from the Swedish Heart Failure Registry","volume":"16","author":"Sartipy","year":"2014","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.hfc.2014.04.012_bib28","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1093\/eurjhf\/hft101","article-title":"Known and missing left ventricular ejection fraction and survival in patients with heart failure: a MAGGIC meta-analysis report","volume":"15","author":"Poppe","year":"2013","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.hfc.2014.04.012_bib29","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1016\/j.jacc.2012.04.064","article-title":"What have we learned about patients with heart failure and preserved ejection fraction from DIG-PEF, CHARM-preserved, and I-PRESERVE?","volume":"60","author":"Campbell","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.hfc.2014.04.012_bib30","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1161\/CIRCULATIONAHA.109.909614","article-title":"Mode of death in patients with heart failure and a preserved ejection fraction: results from the Irbesartan in Heart Failure with Preserved Ejection Fraction Study (I-Preserve) trial","volume":"121","author":"Zile","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.hfc.2014.04.012_bib31","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1161\/01.CIR.0000144474.65922.AA","article-title":"Effect of candesartan on cause-specific mortality in heart failure patients: the Candesartan in Heart failure Assessment of Reduction in Mortality and morbidity (CHARM) program","volume":"110","author":"Solomon","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.hfc.2014.04.012_bib32","doi-asserted-by":"crossref","first-page":"3738","DOI":"10.1161\/CIRCULATIONAHA.105.561423","article-title":"Influence of ejection fraction on cardiovascular outcomes in a broad spectrum of heart failure patients","volume":"112","author":"Solomon","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.hfc.2014.04.012_bib33","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1161\/CIRCHEARTFAILURE.107.743146","article-title":"Death in heart failure: a community perspective","volume":"1","author":"Henkel","year":"2008","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.hfc.2014.04.012_bib34","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1016\/j.ahj.2008.07.011","article-title":"Why and when do patients with heart failure and normal left ventricular ejection fraction die? Analysis of\u00a0>600 deaths in a community long-term study","volume":"156","author":"Grigorian-Shamagian","year":"2008","journal-title":"Am Heart J"},{"key":"10.1016\/j.hfc.2014.04.012_bib35","first-page":"473","article-title":"Hospital admissions and deaths due to congestive heart failure in New Zealand, 1988-91","volume":"108","author":"Doughty","year":"1995","journal-title":"N\u00a0Z Med J"},{"key":"10.1016\/j.hfc.2014.04.012_bib36","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1046\/j.1365-2796.1999.00520.x","article-title":"The health care costs of heart failure in Sweden","volume":"246","author":"Ryd\u00e9n-Bergsten","year":"1999","journal-title":"J\u00a0Intern Med"},{"key":"10.1016\/j.hfc.2014.04.012_bib37","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S1388-9842(01)00198-2","article-title":"The current cost of heart failure to the National Health Service in the UK","volume":"4","author":"Stewart","year":"2002","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.hfc.2014.04.012_bib38","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1161\/CIRCULATIONAHA.107.696906","article-title":"Influence of nonfatal hospitalization for heart failure on subsequent mortality in patients with chronic heart failure","volume":"116","author":"Solomon","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.hfc.2014.04.012_bib39","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/j.jacc.2011.11.040","article-title":"Impact of noncardiac comorbidities on morbidity and mortality in a predominantly male population with heart failure and preserved versus reduced ejection fraction","volume":"59","author":"Ather","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.hfc.2014.04.012_bib40","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1093\/eurheartj\/ehl250","article-title":"The perindopril in elderly people with chronic heart failure (PEP-CHF) study","volume":"27","author":"Cleland","year":"2006","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hfc.2014.04.012_bib41","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.cardfail.2009.11.007","article-title":"The effect of renin-angiotensin system inhibitors on mortality and heart failure hospitalization in patients with heart failure and preserved ejection fraction: a systematic review and meta-analysis","volume":"16","author":"Shah","year":"2010","journal-title":"J\u00a0Card Fail"},{"key":"10.1016\/j.hfc.2014.04.012_bib42","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/eurjhf\/hfs194","article-title":"Pharmacological treatment of heart failure with preserved ejection fraction: a glimpse of light at the end of the tunnel?","volume":"15","author":"van Veldhuisen","year":"2013","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.hfc.2014.04.012_bib43","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1056\/NEJMoa030207","article-title":"Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction","volume":"348","author":"Pitt","year":"2003","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.hfc.2014.04.012_bib44","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1056\/NEJM199909023411001","article-title":"The effect of spironolactone on morbidity and mortality in patients with severe heart failure","volume":"341","author":"Pitt","year":"1999","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.hfc.2014.04.012_bib45","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJMoa1009492","article-title":"Eplerenone in patients with systolic heart failure and mild symptoms","volume":"364","author":"Zannad","year":"2011","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.hfc.2014.04.012_bib46","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1001\/jama.2013.905","article-title":"Effect of spironolactone on diastolic function and exercise capacity in patients with heart failure with preserved ejection fraction: the Aldo-DHF randomized controlled trial","volume":"309","author":"Edelmann","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.hfc.2014.04.012_bib47","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1161\/CIRCHEARTFAILURE.112.972794","article-title":"Baseline characteristics of patients in the treatment of preserved cardiac function heart failure with an aldosterone antagonist trial","volume":"6","author":"Shah","year":"2013","journal-title":"Circ Heart Fail"}],"container-title":["Heart Failure Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551713614000361?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551713614000361?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T02:29:58Z","timestamp":1538533798000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1551713614000361"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":47,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["S1551713614000361"],"URL":"https:\/\/doi.org\/10.1016\/j.hfc.2014.04.012","relation":{},"ISSN":["1551-7136"],"issn-type":[{"value":"1551-7136","type":"print"}],"subject":[],"published":{"date-parts":[[2014,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Outcomes in Patients with Heart Failure with Preserved Ejection Fraction","name":"articletitle","label":"Article Title"},{"value":"Heart Failure Clinics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hfc.2014.04.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}