{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T23:47:39Z","timestamp":1792626459755,"version":"4.5.0"},"reference-count":67,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HL61912"],"award-info":[{"award-number":["HL61912"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HL63030"],"award-info":[{"award-number":["HL63030"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HL149742"],"award-info":[{"award-number":["HL149742"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AG063661"],"award-info":[{"award-number":["AG063661"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart Failure Clinics"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.hfc.2020.08.011","type":"journal-article","created":{"date-parts":[[2020,11,19]],"date-time":"2020-11-19T06:26:15Z","timestamp":1605767175000},"page":"149-156","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Measuring Myocardial Energetics with Cardiovascular Magnetic Resonance Spectroscopy"],"prefix":"10.1016","volume":"17","author":[{"given":"Joevin","family":"Sourdon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabra C.","family":"Lewsey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Sch\u00e4r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert G.","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.hfc.2020.08.011_bib1","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1152\/physrev.00006.2004","article-title":"Myocardial substrate metabolism in the normal and failing heart","volume":"85","author":"Stanley","year":"2005","journal-title":"Physiol Rev"},{"issue":"Pt 2","key":"10.1016\/j.hfc.2020.08.011_bib2","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1113\/jphysiol.2005.101444","article-title":"Cardiac system bioenergetics: metabolic basis of the Frank-Starling law","volume":"571","author":"Saks","year":"2006","journal-title":"J\u00a0Physiol"},{"issue":"11","key":"10.1016\/j.hfc.2020.08.011_bib3","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1056\/NEJMra063052","article-title":"The failing heart - an engine out of fuel","volume":"356","author":"Neubauer","year":"2007","journal-title":"N\u00a0Engl J Med"},{"issue":"5","key":"10.1016\/j.hfc.2020.08.011_bib4","doi-asserted-by":"crossref","first-page":"H2218","DOI":"10.1152\/ajpheart.2000.279.5.H2218","article-title":"MRI\/MRS assessment of in\u00a0vivo murine cardiac metabolism, morphology, and function at physiological heart rates","volume":"279","author":"Chacko","year":"2000","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"4","key":"10.1016\/j.hfc.2020.08.011_bib5","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1002\/nbm.1352","article-title":"Cardiac effects of MDMA on the metabolic profile determined with 1H-magnetic resonance spectroscopy in the rat","volume":"22","author":"Perrine","year":"2009","journal-title":"NMR Biomed"},{"issue":"4715","key":"10.1016\/j.hfc.2020.08.011_bib6","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1126\/science.4023711","article-title":"Noninvasive study of high-energy phosphate metabolism in human heart by depth-resolved 31P NMR spectroscopy","volume":"229","author":"Bottomley","year":"1985","journal-title":"Science"},{"issue":"11","key":"10.1016\/j.hfc.2020.08.011_bib7","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1002\/nbm.2961","article-title":"Quantification of human high-energy phosphate metabolite concentrations at 3 T with partial volume and sensitivity corrections","volume":"26","author":"El-Sharkawy","year":"2013","journal-title":"NMR Biomed"},{"issue":"2","key":"10.1016\/j.hfc.2020.08.011_bib8","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1002\/mrm.24922","article-title":"Human cardiac 31P magnetic resonance spectroscopy at 7 Tesla","volume":"72","author":"Rodgers","year":"2014","journal-title":"Magn Reson Med"},{"issue":"24","key":"10.1016\/j.hfc.2020.08.011_bib9","doi-asserted-by":"crossref","first-page":"8747","DOI":"10.1073\/pnas.82.24.8747","article-title":"Noninvasive detection and monitoring of regional myocardial ischemia in situ using depth-resolved 31P NMR spectroscopy","volume":"82","author":"Bottomley","year":"1985","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"12","key":"10.1016\/j.hfc.2020.08.011_bib10","doi-asserted-by":"crossref","first-page":"4283","DOI":"10.1073\/pnas.84.12.4283","article-title":"Quantitative studies of human cardiac metabolism by 31P rotating-frame NMR","volume":"84","author":"Blackledge","year":"1987","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"3","key":"10.1016\/j.hfc.2020.08.011_bib11","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1002\/mrm.1910140302","article-title":"Phosphate metabolite imaging and concentration measurements in human heart by nuclear magnetic resonance","volume":"14","author":"Bottomley","year":"1990","journal-title":"Magn Reson Med"},{"issue":"1","key":"10.1016\/j.hfc.2020.08.011_bib12","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1161\/01.CIR.92.1.15","article-title":"Quantitative measurements of cardiac phosphorus metabolites in coronary artery disease by 31P magnetic resonance spectroscopy","volume":"92","author":"Yabe","year":"1995","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.hfc.2020.08.011_bib13","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1002\/mrm.1910350507","article-title":"Human cardiac high-energy phosphate metabolite concentrations by 1D-resolved NMR spectroscopy","volume":"35","author":"Bottomley","year":"1996","journal-title":"Magn Reson Med"},{"issue":"5","key":"10.1016\/j.hfc.2020.08.011_bib14","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1002\/mrm.1910390515","article-title":"Influence of aging or left ventricular hypertrophy on the human heart: Contents of phosphorus metabolites measured by 31P MRS","volume":"39","author":"Okada","year":"1998","journal-title":"Magn Reson Med"},{"issue":"4","key":"10.1016\/j.hfc.2020.08.011_bib15","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1002\/(SICI)1522-2594(199904)41:4<657::AID-MRM3>3.0.CO;2-I","article-title":"Concentrations of human cardiac phosphorus metabolites determined by SLOOP 31P NMR spectroscopy","volume":"41","author":"Meininger","year":"1999","journal-title":"Magn Reson Med"},{"issue":"5","key":"10.1016\/j.hfc.2020.08.011_bib16","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1002\/mus.20156","article-title":"Cardiac and skeletal muscle involvement in myotonic dystrophy type 2 (DM2): a quantitative 31P-MRS and MRI study","volume":"30","author":"Schneider-Gold","year":"2004","journal-title":"Muscle Nerve"},{"issue":"3","key":"10.1016\/j.hfc.2020.08.011_bib17","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1073\/pnas.0408962102","article-title":"ATP flux through creatine kinase in the normal, stressed, and failing human heart","volume":"102","author":"Weiss","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"11","key":"10.1016\/j.hfc.2020.08.011_bib18","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1161\/CIRCULATIONAHA.106.613646","article-title":"Altered creatine kinase adenosine triphosphate kinetics in failing hypertrophied human myocardium","volume":"114","author":"Smith","year":"2006","journal-title":"Circulation"},{"issue":"14","key":"10.1016\/j.hfc.2020.08.011_bib19","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1161\/CIRCULATIONAHA.108.823187","article-title":"Reduced myocardial creatine kinase flux in human myocardial infarction","volume":"119","author":"Bottomley","year":"2009","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.hfc.2020.08.011_bib20","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/j.amjcard.2013.05.017","article-title":"Creatine kinase adenosine triphosphate and phosphocreatine energy supply in a single kindred of patients with hypertrophic cardiomyopathy","volume":"112","author":"Abraham","year":"2013","journal-title":"Am J Cardiol"},{"issue":"6","key":"10.1016\/j.hfc.2020.08.011_bib21","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1002\/mrm.22347","article-title":"Triple repetition time saturation transfer (TRiST) 31P spectroscopy for measuring human creatine kinase reaction kinetics","volume":"63","author":"Sch\u00e4r","year":"2010","journal-title":"Magn Reson Med"},{"issue":"1","key":"10.1016\/j.hfc.2020.08.011_bib22","doi-asserted-by":"crossref","DOI":"10.1186\/s12968-015-0175-4","article-title":"Two repetition time saturation transfer (TwiST) with spill-over correction to measure creatine kinase reaction rates in human hearts","volume":"17","author":"Sch\u00e4r","year":"2015","journal-title":"J\u00a0Cardiovasc Magn Reson"},{"issue":"6","key":"10.1016\/j.hfc.2020.08.011_bib23","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1002\/nbm.3103","article-title":"Reproducibility of creatine kinase reaction kinetics in human heart: a 31P time-dependent saturation transfer spectroscopy study","volume":"27","author":"Bashir","year":"2014","journal-title":"NMR Biomed"},{"issue":"1","key":"10.1016\/j.hfc.2020.08.011_bib24","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1002\/mrm.26357","article-title":"Creatine kinase rate constant in the human heart measured with 3D-localization at 7 tesla","volume":"78","author":"Clarke","year":"2017","journal-title":"Magn Reson Med"},{"issue":"9","key":"10.1016\/j.hfc.2020.08.011_bib25","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/j.jacc.2011.10.895","article-title":"Allopurinol acutely increases adenosine triphospate energy delivery in failing human hearts","volume":"59","author":"Hirsch","year":"2012","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"1","key":"10.1016\/j.hfc.2020.08.011_bib26","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s12968-019-0529-4","article-title":"Measuring inorganic phosphate and intracellular pH in the healthy and hypertrophic cardiomyopathy hearts by in\u00a0vivo 7T 31P-cardiovascular magnetic resonance spectroscopy","volume":"21","author":"Valkovi\u010d","year":"2019","journal-title":"J\u00a0Cardiovasc Magn Reson"},{"issue":"1","key":"10.1016\/j.hfc.2020.08.011_bib27","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1002\/mrm.1910070108","article-title":"Very rapid lactate measurement in ischemic perfused hearts using 1H MRS continuous negative echo acquisition during steady-state frequency selective excitation","volume":"7","author":"Keller","year":"1988","journal-title":"Magn Reson Med"},{"issue":"5","key":"10.1016\/j.hfc.2020.08.011_bib28","doi-asserted-by":"crossref","first-page":"E935","DOI":"10.1152\/ajpendo.00095.2005","article-title":"Determination of triglyceride in the human myocardium by magnetic resonance spectroscopy: reproducibility and sensitivity of the method","volume":"289","author":"Reingold","year":"2005","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"2","key":"10.1016\/j.hfc.2020.08.011_bib29","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1210\/jc.2007-2015","article-title":"Progressive caloric restriction induces dose-dependent changes in myocardial triglyceride content and diastolic function in healthy men","volume":"93","author":"Hammer","year":"2008","journal-title":"J\u00a0Clin Endocrinol Metab"},{"issue":"9104","key":"10.1016\/j.hfc.2020.08.011_bib30","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/S0140-6736(97)06402-7","article-title":"Non-invasive magnetic-resonance detection of creatine depletion in non-viable infarcted myocardium","volume":"351","author":"Bottomley","year":"1998","journal-title":"Lancet"},{"issue":"18","key":"10.1016\/j.hfc.2020.08.011_bib31","doi-asserted-by":"crossref","first-page":"10158","DOI":"10.1073\/pnas.1733835100","article-title":"Increase in signal-to-noise ratio of\u00a0> 10,000 times in liquid-state NMR","volume":"100","author":"Ardenkjaer-Larsen","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"5","key":"10.1016\/j.hfc.2020.08.011_bib32","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1002\/mrm.21460","article-title":"Cardiac metabolism measured noninvasively by hyperpolarized 13C MRI","volume":"59","author":"Golman","year":"2008","journal-title":"Magn Reson Med"},{"issue":"14","key":"10.1016\/j.hfc.2020.08.011_bib33","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1161\/CIRCULATIONAHA.111.024919","article-title":"Hyperpolarized magnetic resonance: a novel technique for the in\u00a0vivo assessment of cardiovascular disease","volume":"124","author":"Schroeder","year":"2011","journal-title":"Circulation"},{"issue":"8","key":"10.1016\/j.hfc.2020.08.011_bib34","doi-asserted-by":"crossref","first-page":"2529","DOI":"10.1096\/fj.09-129171","article-title":"Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy","volume":"23","author":"Schroeder","year":"2009","journal-title":"FASEB J"},{"key":"10.1016\/j.hfc.2020.08.011_bib35","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1186\/1532-429X-15-93","article-title":"Clinical implications of cardiac hyperpolarized magnetic resonance imaging","volume":"15","author":"Rider","year":"2013","journal-title":"J\u00a0Cardiovasc Magn Reson"},{"issue":"2","key":"10.1016\/j.hfc.2020.08.011_bib36","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/0022-2364(78)90156-7","article-title":"Phosphorus nuclear magnetic resonance studies of heart physiology","volume":"29","author":"Hollis","year":"1978","journal-title":"J\u00a0Magn Reson (1969)"},{"issue":"5596","key":"10.1016\/j.hfc.2020.08.011_bib37","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1038\/265756a0","article-title":"Phosphorus nuclear magnetic resonance of perfused working rat hearts","volume":"265","author":"Jacobus","year":"1977","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.hfc.2020.08.011_bib38","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1042\/bj1840547","article-title":"Studies of acidosis in the ischaemic heart by phosphorus nuclear magnetic resonance","volume":"184","author":"Garlick","year":"1979","journal-title":"Biochem J"},{"issue":"4","key":"10.1016\/j.hfc.2020.08.011_bib39","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1161\/01.CIR.80.4.969","article-title":"Assessment of myocardial salvage after ischemia and reperfusion using magnetic resonance imaging and spectroscopy","volume":"80","author":"Wolfe","year":"1989","journal-title":"Circulation"},{"issue":"23","key":"10.1016\/j.hfc.2020.08.011_bib40","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1056\/NEJM199012063232304","article-title":"Regional Myocardial Metabolism of High-Energy Phosphates during Isometric Exercise in Patients with Coronary Artery Disease","volume":"323","author":"Weiss","year":"1990","journal-title":"N\u00a0Engl J Med"},{"issue":"12","key":"10.1016\/j.hfc.2020.08.011_bib41","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1056\/NEJM200003233421201","article-title":"Abnormal myocardial phosphorus-31 nuclear magnetic resonance spectroscopy in women with chest pain but normal coronary angiograms","volume":"342","author":"Buchthal","year":"2000","journal-title":"N\u00a0Engl J Med"},{"issue":"4","key":"10.1016\/j.hfc.2020.08.011_bib42","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1161\/01.CIR.89.4.1709","article-title":"Detection of myocardial ischemia by 31P magnetic resonance spectroscopy during handgrip exercise","volume":"89","author":"Yabe","year":"1994","journal-title":"Circulation"},{"issue":"12","key":"10.1016\/j.hfc.2020.08.011_bib43","doi-asserted-by":"crossref","first-page":"3527","DOI":"10.1161\/01.CIR.92.12.3527","article-title":"31P nuclear magnetic resonance spectroscopic imaging of regions of remodeled myocardium in the infarcted rat heart","volume":"92","author":"Friedrich","year":"1995","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.hfc.2020.08.011_bib44","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1148\/radiology.219.2.r01ma39411","article-title":"Noninvasive localized MR quantification of creatine kinase metabolites in normal and infarcted canine myocardium","volume":"219","author":"Bottomley","year":"2001","journal-title":"Radiology"},{"issue":"17","key":"10.1016\/j.hfc.2020.08.011_bib45","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1161\/01.CIR.99.17.2261","article-title":"Diastolic dysfunction in hypertensive heart disease is associated with altered myocardial metabolism","volume":"99","author":"Lamb","year":"1999","journal-title":"Circulation"},{"issue":"24","key":"10.1016\/j.hfc.2020.08.011_bib46","doi-asserted-by":"crossref","first-page":"3040","DOI":"10.1161\/01.CIR.0000072789.89096.10","article-title":"Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes","volume":"107","author":"Scheuermann-Freestone","year":"2003","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.hfc.2020.08.011_bib47","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/S0735-1097(03)00625-9","article-title":"Diastolic dysfunction is associated with altered myocardial metabolism in asymptomatic normotensive patients with well-controlled type 2 diabetes mellitus","volume":"42","author":"Diamant","year":"2003","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"10","key":"10.1016\/j.hfc.2020.08.011_bib48","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1161\/CIRCULATIONAHA.109.873273","article-title":"Relationship between coronary microvascular dysfunction and cardiac energetics impairment in type 1 diabetes mellitus","volume":"121","author":"Shivu","year":"2010","journal-title":"Circulation"},{"issue":"12","key":"10.1016\/j.hfc.2020.08.011_bib49","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1161\/CIRCULATIONAHA.111.069518","article-title":"Effects of catecholamine stress on diastolic function and myocardial energetics in obesity","volume":"125","author":"Rider","year":"2012","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.hfc.2020.08.011_bib50","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1253\/circj.69.711","article-title":"Myocardial creatine concentration in various nonischemic heart diseases assessed by 1H magnetic resonance spectroscopy","volume":"69","author":"Nakae","year":"2005","journal-title":"Circ J"},{"issue":"8","key":"10.1016\/j.hfc.2020.08.011_bib51","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.7326\/0003-4819-12-8-1233","article-title":"The chemical nature of heart failure","volume":"12","author":"Herrmann","year":"1939","journal-title":"Ann Intern Med"},{"issue":"1","key":"10.1016\/j.hfc.2020.08.011_bib52","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/00005792-195102000-00002","article-title":"Myocardial metabolism in congestive heart failure","volume":"30","author":"Olson","year":"1951","journal-title":"Medicine (Baltimore)"},{"issue":"20","key":"10.1016\/j.hfc.2020.08.011_bib53","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1161\/01.CIR.100.20.2113","article-title":"Progressive loss of myocardial ATP due to a loss of total purines during the development of heart failure in dogs: a compensatory role for the parallel loss of creatine","volume":"100","author":"Shen","year":"1999","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.hfc.2020.08.011_bib54","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1023\/A:1006876031121","article-title":"Human\u00a0myocardial ATP content and in\u00a0vivo contractile function","volume":"180","author":"Starling","year":"1998","journal-title":"Mol Cell Biochem"},{"issue":"17","key":"10.1016\/j.hfc.2020.08.011_bib55","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1056\/NEJM198510243131704","article-title":"The creatine kinase system in normal and diseased human myocardium","volume":"313","author":"Ingwall","year":"1985","journal-title":"N\u00a0Engl J Med"},{"issue":"8","key":"10.1016\/j.hfc.2020.08.011_bib56","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.1161\/01.CIR.94.8.1894","article-title":"Creatine kinase system in failing and nonfailing human myocardium","volume":"94","author":"Nascimben","year":"1996","journal-title":"Circulation"},{"issue":"3 Pt 1","key":"10.1016\/j.hfc.2020.08.011_bib57","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/0002-8703(91)90527-O","article-title":"Altered myocardial high-energy phosphate metabolites in patients with dilated cardiomyopathy","volume":"122","author":"Hardy","year":"1991","journal-title":"Am Heart J"},{"issue":"8773","key":"10.1016\/j.hfc.2020.08.011_bib58","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/0140-6736(91)91838-L","article-title":"Detection of low phosphocreatine to ATP ratio in failing hypertrophied human myocardium by 31P magnetic resonance spectroscopy","volume":"338","author":"Conway","year":"1991","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.hfc.2020.08.011_bib59","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1161\/01.CIR.86.6.1810","article-title":"31P magnetic resonance spectroscopy in dilated cardiomyopathy and coronary artery disease. Altered cardiac high-energy phosphate metabolism in heart failure","volume":"86","author":"Neubauer","year":"1992","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.hfc.2020.08.011_bib60","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1253\/jcj.56.620","article-title":"High-energy phosphate metabolism of the myocardium in normal subjects and patients with various cardiomyopathies--the study using ECG gated MR spectroscopy with a localization technique","volume":"56","author":"Masuda","year":"1992","journal-title":"Jpn Circ J"},{"issue":"6","key":"10.1016\/j.hfc.2020.08.011_bib61","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1002\/jmri.1880020616","article-title":"Cardiac metabolism in patients with dilated and hypertrophic cardiomyopathy: assessment with proton-decoupled P-31 MR spectroscopy","volume":"2","author":"de Roos","year":"1992","journal-title":"J\u00a0Magn Reson Imaging"},{"issue":"1","key":"10.1016\/j.hfc.2020.08.011_bib62","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/0002-8703(89)90076-8","article-title":"The effect of dobutamine on myocardial performance and high-energy phosphate metabolism at different stages of heart failure in cardiomyopathic hamsters: a 31P MRS study","volume":"118","author":"Buser","year":"1989","journal-title":"Am Heart J"},{"issue":"215","key":"10.1016\/j.hfc.2020.08.011_bib63","doi-asserted-by":"crossref","first-page":"215re3","DOI":"10.1126\/scitranslmed.3007328","article-title":"Metabolic rates of ATP transfer through creatine kinase (CK Flux) predict clinical heart failure events and death","volume":"5","author":"Bottomley","year":"2013","journal-title":"Sci Transl Med"},{"issue":"1","key":"10.1016\/j.hfc.2020.08.011_bib64","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/s12968-018-0491-6","article-title":"Cardiac work is related to creatine kinase energy supply in human heart failure: a cardiovascular magnetic resonance spectroscopy study","volume":"20","author":"Gabr","year":"2018","journal-title":"J\u00a0Cardiovasc Magn Reson"},{"issue":"14","key":"10.1016\/j.hfc.2020.08.011_bib65","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1096\/fj.04-2263com","article-title":"Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart","volume":"18","author":"Sharma","year":"2004","journal-title":"FASEB J"},{"issue":"10","key":"10.1016\/j.hfc.2020.08.011_bib66","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/j.cardfail.2010.05.006","article-title":"Clinical features of myocardial triglyceride in different types of cardiomyopathy assessed by proton magnetic resonance spectroscopy: comparison with myocardial creatine","volume":"16","author":"Nakae","year":"2010","journal-title":"J\u00a0Card Fail"},{"issue":"7","key":"10.1016\/j.hfc.2020.08.011_bib67","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1161\/01.CIR.96.7.2190","article-title":"Myocardial phosphocreatine-to-ATP ratio is a predictor of mortality in patients with dilated cardiomyopathy","volume":"96","author":"Neubauer","year":"1997","journal-title":"Circulation"}],"container-title":["Heart Failure Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551713620300696?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1551713620300696?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T08:39:57Z","timestamp":1761554397000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1551713620300696"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":67,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["S1551713620300696"],"URL":"https:\/\/doi.org\/10.1016\/j.hfc.2020.08.011","relation":{},"ISSN":["1551-7136"],"issn-type":[{"value":"1551-7136","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Measuring Myocardial Energetics with Cardiovascular Magnetic Resonance Spectroscopy","name":"articletitle","label":"Article Title"},{"value":"Heart Failure Clinics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hfc.2020.08.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}