{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T03:45:22Z","timestamp":1790394322961,"version":"4.1.0"},"reference-count":25,"publisher":"ARAN Ediciones","issue":"4","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hipertensi\u00f3n y Riesgo Vascular"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.hipert.2018.01.004","type":"journal-article","created":{"date-parts":[[2018,2,15]],"date-time":"2018-02-15T08:54:26Z","timestamp":1518684866000},"page":"169-176","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Neurocognitive disorder in hypertensive patients. Heart\u2013Brain Study"],"prefix":"10.20960","volume":"35","author":[{"given":"A.","family":"Vicario","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.H.","family":"Cerezo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"del Sueldo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Zilberman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.M.","family":"Pawluk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"L\u00f3dolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.E.","family":"De Cerchio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.M.","family":"Ruffa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Plunkett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.E.","family":"Giuliano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Forcada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Hauad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Flores","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"8588","reference":[{"key":"10.1016\/j.hipert.2018.01.004_bib0130","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1161\/HYPERTENSIONAHA.111.186429","article-title":"Hypertension and cognitive functioning: a perspective in historical context","volume":"60","author":"Elias","year":"2012","journal-title":"Hypertension"},{"key":"10.1016\/j.hipert.2018.01.004_bib0135","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1001\/jama.1997.03540340047031","article-title":"Infarction and the clinical expression of Alzheimer disease. The Nun Study","volume":"277","author":"Snowdon","year":"1997","journal-title":"JAMA"},{"key":"10.1016\/j.hipert.2018.01.004_bib0140","first-page":"1","article-title":"Gu\u00eda para la Evaluaci\u00f3n de Trastornos Cognitivos en pacientes con Enfermedad Vascular. 2da. Edici\u00f3n. Actualizaci\u00f3n 2013","volume":"42","author":"Vicario","year":"2013","journal-title":"Rev Arg Fed Cardiol"},{"key":"10.1016\/j.hipert.2018.01.004_bib0145","first-page":"311","article-title":"Psychiatric screening in general practice: comparison of the general health questionnaire and the hospital anxiety and depression scale","volume":"38","author":"Wilkinson","year":"1988","journal-title":"J Roy Coll Gen Pract"},{"key":"10.1016\/j.hipert.2018.01.004_bib0150","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1001\/archneur.60.10.1385","article-title":"Prevalence and classification of mild cognitive impairment in the Cardiovascular Health Study Cognition Study: Part 1","volume":"60","author":"Lopez","year":"2003","journal-title":"Arch Neurol"},{"key":"10.1016\/j.hipert.2018.01.004_bib0155","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1212\/WNL.0b013e3181f11d85","article-title":"Prevalence of mild cognitive impairment is higher in men: the Mayo Clinic Study of Aging","volume":"75","author":"Petersen","year":"2010","journal-title":"Neurology"},{"key":"10.1016\/j.hipert.2018.01.004_bib0160","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1111\/j.1524-6175.2005.04498.x","article-title":"Hypertension and cognitive decline: impact on executive function","volume":"7","author":"Vicario","year":"2005","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"10.1016\/j.hipert.2018.01.004_bib0165","first-page":"1","article-title":"Cognitive evolution in hypertensive patients: a six-years follow-up","volume":"7","author":"Vicario","year":"2011","journal-title":"Vasc Health Risk Manage"},{"key":"10.1016\/j.hipert.2018.01.004_bib0170","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1161\/STROKEAHA.115.009589","article-title":"Long-term blood-brain barrier permeability changes in Binswagner disease","volume":"46","author":"Huisa","year":"2015","journal-title":"Stroke"},{"key":"10.1016\/j.hipert.2018.01.004_bib0175","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.neurobiolaging.2007.07.015","article-title":"Blood-brain barrier: ageing and microvascular disease-systematic review and meta-analysis","volume":"30","author":"Farrall","year":"2009","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.hipert.2018.01.004_bib0180","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1002\/acn3.27","article-title":"Hypertension drives parenchymal \u03b2-amyloid accumulation in the brain parenchyma","volume":"1","author":"Bueche","year":"2014","journal-title":"Ann Clin Transl Neurol"},{"key":"10.1016\/j.hipert.2018.01.004_bib0185","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1001\/jamaneurol.2013.1342","article-title":"Risk factor for beta-amyloid deposition in healthy aging","volume":"70","author":"Rodrigue","year":"2013","journal-title":"JAMA Neurol"},{"key":"10.1016\/j.hipert.2018.01.004_bib0190","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1001\/jamaneurol.2013.1862","article-title":"Contribution of cerebrovascular health to the diagnosis of Alzheimer disease","volume":"70","author":"Rodrigue","year":"2013","journal-title":"JAMA Neurol"},{"key":"10.1016\/j.hipert.2018.01.004_bib0195","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1007\/s007020200068","article-title":"Alzheimer disease and cerebrovascular pathology: an update","volume":"109","author":"Jellinger","year":"2002","journal-title":"J Neurol Transm"},{"key":"10.1016\/j.hipert.2018.01.004_bib0200","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1001\/archneur.1995.00540310076019","article-title":"Cerebral infarction in Alzheimer's disease is associated with severe amyloid angiopathy and hypertension","volume":"52","author":"Olichney","year":"1995","journal-title":"Arch Neurol"},{"key":"10.1016\/j.hipert.2018.01.004_bib0205","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1161\/STROKEAHA.107.497438","article-title":"Spatial distribution of white matter hyperintensities in Alzheimer disease, cerebral amyloid angiopathy, and healthy aging","volume":"39","author":"Holland","year":"2008","journal-title":"Stroke"},{"key":"10.1016\/j.hipert.2018.01.004_bib0210","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0197-4580(00)00096-8","article-title":"Midlife blood pressure and dementia: the Honolulu-Asia aging study","volume":"21","author":"Launer","year":"2000","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.hipert.2018.01.004_bib0215","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/S0140-6736(96)90608-X","article-title":"15-Year longitudinal study of blood pressure and dementia","volume":"347","author":"Skoog","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.hipert.2018.01.004_bib0220","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1001\/archinte.162.18.2046","article-title":"The prevention of dementia with antihypertensive treatment: new evidence from the Systolic Hypertension in Europe (Syst-Eur)","volume":"162","author":"Forette","year":"2002","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.hipert.2018.01.004_bib0225","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1111\/jch.12643","article-title":"Association between hypertension. Menopause, and cognition in women","volume":"17","author":"Zilberman","year":"2015","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"10.1016\/j.hipert.2018.01.004_bib0230","unstructured":"Prince M, Albanese E, Guerchet M, Prina M. World Alzheimer Report 2014. Dementia and Risk Reduction. An analysis of protective and modifiable factors. Available at: https:\/\/www.alz.co.uk\/research\/WorldAlzheimerReport2014.pdf."},{"key":"10.1016\/j.hipert.2018.01.004_bib0235","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.jalz.2012.09.012","article-title":"The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER): study design and progress","volume":"9","author":"Kivipelto","year":"2013","journal-title":"Alzheimer's Dement"},{"key":"10.1016\/j.hipert.2018.01.004_bib0240","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/S0140-6736(04)17018-9","article-title":"Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (THE INTERHEART STUDY): case\u2013control study","volume":"364","author":"Yusuf","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.hipert.2018.01.004_bib0245","series-title":"Epidemiolog\u00eda de los trastornos mentales en Am\u00e9rica Latina y el Caribe","author":"Rodriguez","year":"2009"},{"key":"10.1016\/j.hipert.2018.01.004_bib0250","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1192\/bjp.bp.112.118307","article-title":"Late-life depression and risk of vascular dementia and Alzheimer's disease: systematic review and meta-analysis of community-based cohort studies","volume":"202","author":"Diniz","year":"2013","journal-title":"Br J Psychiatry"}],"container-title":["Hipertensi\u00f3n y Riesgo Vascular"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1889183718300072?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1889183718300072?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T01:15:07Z","timestamp":1784596507000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1889183718300072"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["S1889183718300072"],"URL":"https:\/\/doi.org\/10.1016\/j.hipert.2018.01.004","relation":{},"ISSN":["1889-1837"],"issn-type":[{"value":"1889-1837","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neurocognitive disorder in hypertensive patients. Heart\u2013Brain Study","name":"articletitle","label":"Article Title"},{"value":"Hipertensi\u00f3n y Riesgo Vascular","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hipert.2018.01.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 SEH-LELHA. Published by Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}]}}