{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T23:08:43Z","timestamp":1765667323638,"version":"build-2065373602"},"reference-count":62,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,2,14]],"date-time":"2021-02-14T00:00:00Z","timestamp":1613260800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hellenic Journal of Cardiology"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.hjc.2021.02.003","type":"journal-article","created":{"date-parts":[[2021,2,21]],"date-time":"2021-02-21T07:42:37Z","timestamp":1613893357000},"page":"423-428","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["The effect of Remote Ischemic Preconditioning (RIPC) on myocardial injury and inflammation in patients with severe aortic valve stenosis undergoing Transcatheter Aortic Valve Replacement (TAV\u0399)"],"prefix":"10.1016","volume":"62","author":[{"given":"Antonios","family":"Halapas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alkistis","family":"Kapelouzou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Chrissoheris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory","family":"Pattakos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6909-7846","authenticated-orcid":false,"given":"Dennis V.","family":"Cokkinos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Spargias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.hjc.2021.02.003_bib1","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1016\/S0140-6736(15)60290-2","article-title":"5-year outcomes of transcatheter aortic valve replacement compared with standard treatment for patients with inoperable aortic stenosis (PARTNER 1): a randomized controlled trial","volume":"385","author":"Kapadia","year":"2015","journal-title":"Lancet"},{"key":"10.1016\/j.hjc.2021.02.003_bib2","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1016\/S0140-6736(15)60308-7","article-title":"5-year outcomes of transcatheter aortic valve replacement or surgical aortic valve replacement for high surgical risk patients with aortic stenosis (PARTNER 1): a randomized controlled trial","volume":"385","author":"Mack","year":"2015","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.hjc.2021.02.003_bib3","doi-asserted-by":"crossref","first-page":"e617","DOI":"10.4244\/EIJV13I5A97","article-title":"The SURTAVI study: TAVI for patients with intermediate risk","volume":"13","author":"Jones","year":"2017","journal-title":"EuroIntervention"},{"key":"10.1016\/j.hjc.2021.02.003_bib4","doi-asserted-by":"crossref","first-page":"1988","DOI":"10.1016\/j.jacc.2010.11.060","article-title":"Incidence, predictive factors, and prognostic value of myocardial injury following uncomplicated transcatheter aortic valve implantation","volume":"57","author":"Rodes-Cabau","year":"2011","journal-title":"JACC"},{"key":"10.1016\/j.hjc.2021.02.003_bib5","first-page":"518","article-title":"Impact of postoperative acute kidney injury on clinical outcomes after transcatheter aortic valve implantation: a meta-analysis of 5,971 patients","volume":"86","author":"Gargiulo","year":"2015","journal-title":"Cathet Cardiovasc Interv"},{"key":"10.1016\/j.hjc.2021.02.003_bib6","doi-asserted-by":"crossref","first-page":"129","DOI":"10.4244\/EIJV8I1A20","article-title":"Risk of stroke after transcatheter aortic valve implantation (TAVI): a meta-analysis of 10,037 published patients","volume":"8","author":"Eggebrecht","year":"2012","journal-title":"EuroIntervention"},{"key":"10.1016\/j.hjc.2021.02.003_bib7","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1093\/eurheartj\/ehs002","article-title":"Systemic inflammatory response syndrome predicts increased mortality in patients after transcatheter aortic valve implantation","volume":"33","author":"Sinning","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hjc.2021.02.003_bib8","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.jacc.2014.10.031","article-title":"Remote ischemic conditioning","volume":"65","author":"Heusch","year":"2015","journal-title":"JACC"},{"key":"10.1016\/j.hjc.2021.02.003_bib9","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1161\/CIRCRESAHA.116.308736","article-title":"Time to give up on cardioprotection? A critical appraisal of clinical studies on ischemic pre-, post-, and remote conditioning","volume":"119","author":"Heusch","year":"2016","journal-title":"Circ Res"},{"key":"10.1016\/j.hjc.2021.02.003_bib10","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/S0140-6736(09)62001-8","article-title":"Remote ischaemic conditioning before hospital admission, as a complement to angioplasty, and effect on myocardial salvage in patients with acute myocardial infarction: a randomized trial","volume":"375","author":"B\u00f8tker","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.hjc.2021.02.003_bib11","doi-asserted-by":"crossref","first-page":"2764","DOI":"10.1016\/j.jacc.2015.02.082","article-title":"Remote ischemic conditioning reduces myocardial infarct size in STEMI patients treated by thrombolysis","volume":"65","author":"Yellon","year":"2015","journal-title":"JACC"},{"key":"10.1016\/j.hjc.2021.02.003_bib12","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1161\/CIRCULATIONAHA.108.809723","article-title":"Cardiac remote ischemic preconditioning in coronary stenting (CRISP stent) study: a prospective, randomized control trial","volume":"119","author":"Hoole","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.hjc.2021.02.003_bib13","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/S0140-6736(13)61450-6","article-title":"Cardioprotective and prognostic effects of remote ischemic preconditioning in patients undergoing coronary artery bypass surgery: a single-center randomized, double-blind, controlled trial","volume":"382","author":"Thielmann","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.hjc.2021.02.003_bib14","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1161\/CIRCINTERVENTIONS.112.000184","article-title":"Remote ischemic preconditioning improves outcome at 6 years after elective percutaneous coronary intervention: the CRISP stent trial long-term follow up","volume":"6","author":"Davies","year":"2013","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.hjc.2021.02.003_bib15","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1056\/NEJMoa1413579","article-title":"A multicenter trial of remote ischemic preconditioning for heart surgery","volume":"373","author":"Meybohm","year":"2015","journal-title":"NEJM"},{"key":"10.1016\/j.hjc.2021.02.003_bib16","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1056\/NEJMoa1413534","article-title":"Remote ischemic preconditioning and outcomes of cardiac surgery","volume":"373","author":"Hausenloy","year":"2015","journal-title":"NEJM"},{"key":"10.1016\/j.hjc.2021.02.003_bib17","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.ijcard.2016.12.005","article-title":"No Protection of Heart, Kidneys and Brain by Remote Ischemic Preconditioning Before Transfemoral Transcatheter Aortic Valve Implantation: Interim-analysis of a Randomized Single-Blinded, Placebo-Controlled, Single- Center Trial","volume":"231","author":"Kahlert","year":"2017","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.hjc.2021.02.003_bib18","doi-asserted-by":"crossref","first-page":"160","DOI":"10.3390\/jcm9010160","article-title":"Remote Ischemic Preconditioning Neither Improves Survival Nor Reduces Myocardial or Kidney Injury in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI)","volume":"7","author":"Flechsig","year":"2020","journal-title":"J Clin Med"},{"key":"10.1016\/j.hjc.2021.02.003_bib19","first-page":"3e7","article-title":"Multi-slice CT (MSCT) imaging in pretrans-catheter aortic valve implantation (TAVI) screening. How to perform and how to interpret","volume":"59","author":"George","year":"2018","journal-title":"Hellenic J Cardiol"},{"key":"10.1016\/j.hjc.2021.02.003_bib20","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.gheart.2018.08.004","article-title":"Fourth universal definition of myocardial infarction (2018)","volume":"13","author":"Thygesen","year":"2018","journal-title":"Glob Heart"},{"key":"10.1016\/j.hjc.2021.02.003_bib21","first-page":"85","article-title":"Acute Kidney Injury: Definition, Pathophysiology and Clinical Phenotypes","volume":"37","author":"Makris","year":"2016","journal-title":"Clin Biochem Rev"},{"key":"10.1016\/j.hjc.2021.02.003_bib22","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1093\/eurheartj\/ehq406","article-title":"Standardized endpoint definitions for transcatheter aortic valve implantation clinical trials: a consensus report from the Valve Academic Research Consortium","volume":"32","author":"Leon","year":"2011","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hjc.2021.02.003_bib23","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1136\/heartjnl-2012-302505","article-title":"Successful transcatheter aortic valve implantation (TAVI) is associated with transient left ventricular dysfunction","volume":"98","author":"Dworakowski","year":"2012","journal-title":"Heart"},{"key":"10.1016\/j.hjc.2021.02.003_bib24","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.1016\/j.athoracsur.2015.01.029","article-title":"Myocardial Injury After Transaortic Versus Transapical Transcatheter Aortic Valve Replacement","volume":"99","author":"Ribeiro","year":"2015","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.hjc.2021.02.003_bib25","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.jacc.2014.03.052","article-title":"Detection of myocardial injury by CMR after transcatheter aortic valve replacement","volume":"64","author":"Kim","year":"2014","journal-title":"JACC"},{"key":"10.1016\/j.hjc.2021.02.003_bib26","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.ahj.2014.12.023","article-title":"Sensitive troponin assays in patients with suspected acute coronary syndrome: Results from the multi-center Rule Out Myocardial Infarction Using Computer Assisted Tomography (ROMICAT) II Trial","volume":"169","author":"Januzzi","year":"2015","journal-title":"Am Heart J"},{"key":"10.1016\/j.hjc.2021.02.003_bib27","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/j.recesp.2016.02.023","article-title":"Prognostic Value of High-sensitivity Troponin T After Percutaneous Coronary Intervention in patients With Stable Coronary Artery Disease","volume":"69","author":"Ndrepepa","year":"2016","journal-title":"Rev Esp Cardiol"},{"key":"10.1016\/j.hjc.2021.02.003_bib28","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.1001\/jama.2012.5502","article-title":"Association Between Postoperative Troponin Levels and 30-Day Mortality Among patients Undergoing Non-cardiac Surgery","volume":"307","author":"Devereaux","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.hjc.2021.02.003_bib29","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.acvd.2018.12.001","article-title":"Which High-Sensitivity Troponin Variable Best Characterizes Infarct Size and Microvascular Obstruction?","volume":"112","author":"Schaaf","year":"2019","journal-title":"Arch Cardiovasc Dis"},{"key":"10.1016\/j.hjc.2021.02.003_bib30","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1016\/j.amjcard.2013.01.301","article-title":"Prognostic value of myocardial injury following transcatheter aortic valve implantation","volume":"111","author":"Carrabba","year":"2013","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.hjc.2021.02.003_bib31","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1111\/j.1365-2362.2007.01803.x","article-title":"Elevated levels of interleukin-1betaconverting enzyme and caspase-cleaved cytokeratin-18 in acute myocardial infarction","volume":"37","author":"Adlbrecht","year":"2007","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.hjc.2021.02.003_bib32","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1097\/MCA.0000000000000416","article-title":"The predictive value of M30 and oxidative stress for left ventricular remodeling in patients with anterior ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention","volume":"27","author":"T\u00fcrko\u011flu","year":"2016","journal-title":"Coron Artery Dis"},{"key":"10.1016\/j.hjc.2021.02.003_bib33","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1097\/MCA.0b013e328330d56a","article-title":"Serial changes in circulating M30 antigen, a biomarker of apoptosis, in patients with acute coronary syndromes: relationship with the severity of coronary artery disease","volume":"20","author":"Senturk","year":"2009","journal-title":"Coron Artery Dis"},{"key":"10.1016\/j.hjc.2021.02.003_bib34","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1093\/cvr\/cvn114","article-title":"Remote ischaemic preconditioning: underlying mechanisms and clinical application","volume":"79","author":"Hausenloy","year":"2008","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.hjc.2021.02.003_bib35","article-title":"The role of ischemic preconditioning in the expression of apoptosis-related genes in a rat model of intestinal ischemia-reperfusion injury","volume":"34","author":"Couto de Miranda","year":"2019","journal-title":"Acta Cir Bras"},{"key":"10.1016\/j.hjc.2021.02.003_bib36","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.jss.2007.12.747","article-title":"Remote ischemic preconditioning: a novel protective method from ischemia reperfusion injury--a review","volume":"150","author":"Tapuria","year":"2008","journal-title":"J Surg Res"},{"key":"10.1016\/j.hjc.2021.02.003_bib37","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1590\/s0102-865020180120000007","article-title":"The role of ischemic preconditioning in gene expression related to inflammation in a rat model of intestinal ischemia-reperfusion injury","volume":"33","author":"Couto de Miranda","year":"2018","journal-title":"Acta Cir Bras"},{"key":"10.1016\/j.hjc.2021.02.003_bib38","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1152\/physiolgenomics.00046.2004","article-title":"The remote ischemic preconditioning stimulus modifies inflammatory gene expression in humans","volume":"19","author":"Konstantinov","year":"2004","journal-title":"Physiol Genomics"},{"key":"10.1016\/j.hjc.2021.02.003_bib39","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jss.2008.08.010","article-title":"Remote ischemic preconditioning decreases adhesion and selectively modifies functional responses of human neutrophils","volume":"158","author":"Shimizu","year":"2010","journal-title":"J Surg Res"},{"key":"10.1016\/j.hjc.2021.02.003_bib40","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.brainresrev.2008.12.020","article-title":"Role of interleukin-1beta During Pain and Inflammation","volume":"60","author":"Ren","year":"2009","journal-title":"Brain Res Rev"},{"key":"10.1016\/j.hjc.2021.02.003_bib41","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.jjcc.2015.06.007","article-title":"Remote ischemic preconditioning in aortic valve surgery: Results of a randomized controlled study","volume":"67","author":"Pinaud","year":"2016","journal-title":"J Cardiol"},{"key":"10.1016\/j.hjc.2021.02.003_bib42","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1053\/j.semtcvs.2019.12.004","article-title":"A Prospective Randomized Blinded Trial of Remote Ischemic Preconditioning in Children Undergoing Cardiac Surgery","volume":"32","author":"Verdesoto Rodriguez","year":"2020","journal-title":"Semin Thorac Cardiovasc Surg"},{"key":"10.1016\/j.hjc.2021.02.003_bib43","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s12974-016-0486-x","article-title":"HSP60 Plays a Regulatory Role in IL-1\u03b2-induced Microglial Inflammation via TLR4-p38 MAPK Axis","volume":"13","author":"Swaroop","year":"2016","journal-title":"J Neuroinflammation"},{"key":"10.1016\/j.hjc.2021.02.003_bib44","first-page":"105","article-title":"Volatile anesthetic myocardial protection: a review of the current literature","volume":"2","author":"Lin","year":"2010","journal-title":"HSR Proc Intensive Care Cardiovasc Anesth"},{"key":"10.1016\/j.hjc.2021.02.003_bib45","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/s12871-015-0107-8","article-title":"Meta-analysis of the cardioprotective effect of sevoflurane versus propofol during cardiac surgery","volume":"15","author":"Li","year":"2015","journal-title":"BMC Anesthesiol"},{"key":"10.1016\/j.hjc.2021.02.003_bib46","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s12871-017-0326-2","article-title":"Comparison of the myocardial protective effect of sevoflurane versus propofol in patients undergoing heart valve replacement surgery with cardiopulmonary bypass","volume":"17","author":"Yang","year":"2017","journal-title":"BMC Anesthesiol"},{"key":"10.1016\/j.hjc.2021.02.003_bib47","doi-asserted-by":"crossref","first-page":"358","DOI":"10.4097\/kjae.2011.61.5.358","article-title":"Morphine and remifentanil-induced cardioprotection: its experimental and clinical outcomes","volume":"61","author":"Kim","year":"2011","journal-title":"Korean J Anesthesiol"},{"issue":"Suppl 1","key":"10.1016\/j.hjc.2021.02.003_bib48","doi-asserted-by":"crossref","first-page":"S23","DOI":"10.1053\/j.jvca.2015.01.021","article-title":"Remifentanil and opioid-induced cardioprotection","volume":"29","author":"Irwin","year":"2015","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"10.1016\/j.hjc.2021.02.003_bib49","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s12871-017-0330-6","article-title":"A Randomized Trial of Remote Ischemic Preconditioning and Control Treatment for Cardioprotection in Sevoflurane-Anesthetized CABG Patients","volume":"17","author":"Nederlof","year":"2017","journal-title":"BMC Anesthesiol"},{"issue":"12","key":"10.1016\/j.hjc.2021.02.003_bib50","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1136\/hrt.2006.089060","article-title":"Increased C Reactive Protein and Cardiac Enzyme Levels After Coronary Stent Implantation. Is There Protection by Remote Ischaemic Preconditioning?","volume":"92","author":"Iliodromitis","year":"2006","journal-title":"Heart"},{"key":"10.1016\/j.hjc.2021.02.003_bib51","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/S0008-6363(02)00288-2","article-title":"Innate Immunity and Cardiac Preconditioning: A Putative Intrinsic Cardioprotective Program","volume":"55","author":"Smith","year":"2002","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.hjc.2021.02.003_bib52","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1152\/physiolgenomics.00166.2004","article-title":"Ischemic but Not Pharmacological Preconditioning Elicits a Gene Expression Profile Similar to Unprotected Myocardium","volume":"20","author":"Da Silva","year":"2004","journal-title":"Physiol Genomics"},{"key":"10.1016\/j.hjc.2021.02.003_bib53","doi-asserted-by":"crossref","first-page":"2186","DOI":"10.1161\/01.CIR.0000127958.21003.5A","article-title":"Serum levels of the interleukin-1 receptor family member ST2 predict mortality and clinical outcome in acute myocardial infarction","volume":"109","author":"Shimpo","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.hjc.2021.02.003_bib54","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1056\/NEJMoa1707914","article-title":"Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease","volume":"377","author":"Ridker","year":"2017","journal-title":"NEJM"},{"key":"10.1016\/j.hjc.2021.02.003_bib55","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.1093\/eurheartj\/ehz206","article-title":"Prevention of radiotherapy-induced arterial inflammation by interleukin-1 blockade","volume":"40","author":"Christersdottir","year":"2019","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hjc.2021.02.003_bib56","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1016\/j.amjcard.2009.12.059","article-title":"Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study)","volume":"105","author":"Abbate","year":"2010","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.hjc.2021.02.003_bib57","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1161\/CIRCULATIONAHA.112.096370","article-title":"Ischemic preconditioning for prevention of contrast mediuminduced nephropathy: randomized pilot RenPro Trial (Renal Protection Trial)","volume":"126","author":"Er","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.hjc.2021.02.003_bib58","doi-asserted-by":"crossref","DOI":"10.1097\/CCM.0000000000001704","article-title":"Is Remote Ischemic Preconditioning Really a Novel Renoprotective Option for Cardiac Surgery?","volume":"44","author":"Xue","year":"2016","journal-title":"Crit Care Med"},{"issue":"4","key":"10.1016\/j.hjc.2021.02.003_bib59","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.hjc.2018.08.008","article-title":"The \u201cethos\u201d and the \u201cagony\u201d of sham-controlled trials in cardiovascular Medicine","volume":"59","author":"Tsioufis","year":"2018","journal-title":"Hellenic J Cardiol"},{"key":"10.1016\/j.hjc.2021.02.003_bib60","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s00395-011-0185-9","article-title":"Remote intermittent ischemia before coronary artery bypass graft surgery: a strategy to reduce injury and inflammation?","volume":"106","author":"Karuppasamy","year":"2011","journal-title":"Basic Res Cardiol"},{"key":"10.1016\/j.hjc.2021.02.003_bib61","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1177\/1074248411402501","article-title":"State of the science of cardioprotection: Challenges and opportunities--proceedings of the 2010 NHLBI Workshop on Cardioprotection","volume":"16","author":"Kloner","year":"2011","journal-title":"J Cardiovasc Pharmacol Ther"},{"key":"10.1016\/j.hjc.2021.02.003_bib62","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1016\/S0140-6736(09)61421-5","article-title":"Translation of remote ischaemic preconditioning into clinical practice","volume":"374","author":"Kharbanda","year":"2009","journal-title":"Lancet"}],"container-title":["Hellenic Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1109966621000166?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1109966621000166?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T02:14:32Z","timestamp":1761099272000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1109966621000166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":62,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["S1109966621000166"],"URL":"https:\/\/doi.org\/10.1016\/j.hjc.2021.02.003","relation":{},"ISSN":["1109-9666"],"issn-type":[{"type":"print","value":"1109-9666"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effect of Remote Ischemic Preconditioning (RIPC) on myocardial injury and inflammation in patients with severe aortic valve stenosis undergoing Transcatheter Aortic Valve Replacement (TAV\u0399)","name":"articletitle","label":"Article Title"},{"value":"Hellenic Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hjc.2021.02.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Hellenic Society of Cardiology. Publishing services by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}