{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T08:44:59Z","timestamp":1763541899724,"version":"3.45.0"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T00:00:00Z","timestamp":1739491200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hellenic Journal of Cardiology"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.hjc.2025.02.003","type":"journal-article","created":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T20:03:18Z","timestamp":1740168198000},"page":"90-98","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Key messages and critical approach of the 2024 guidelines of the European Society of Cardiology on chronic coronary syndromes"],"prefix":"10.1016","volume":"85","author":[{"given":"Athanasios J.","family":"Manolis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Collins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8256-4218","authenticated-orcid":false,"given":"Manolis S.","family":"Kallistratos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Rosano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.hjc.2025.02.003_bib1","first-page":"1","author":"Vrints","year":"2024","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hjc.2025.02.003_bib2","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1056\/NEJMoa1805971","article-title":"Coronary CT angiography and 5-year risk of myocardial infarction","volume":"379","author":"Newby","year":"2018","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hjc.2025.02.003_bib3","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1093\/eurheartj\/ehv700","article-title":"Calcium imaging and selective computed tomography angiography in comparison to functional testing for suspected coronary artery disease: the multicentre, randomized CRESCENT trial","volume":"37","author":"Lubbers","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hjc.2025.02.003_bib4","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1016\/j.jacc.2016.02.026","article-title":"Use of coronary computed tomographic angiography to guide management of patients with coronary disease","volume":"67","author":"Williams","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hjc.2025.02.003_bib5","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1001\/jamacardio.2020.1567","article-title":"Exercise electrocardiography and computed tomography coronary angiography for patients with suspected stable angina pectoris: a post hoc analysis of the randomized SCOT-HEART trial","volume":"5","author":"Singh","year":"2020","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.hjc.2025.02.003_bib6","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1093\/ehjci\/jew049","article-title":"Relative clinical and economic impact of exercise echocardiography vs. exercise electrocardiography, as first line investigation in patients without known coronary artery disease and new stable angina: a randomized prospective study","volume":"18","author":"Zacharias","year":"2017","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.hjc.2025.02.003_bib7","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1093\/ehjci\/jeu284","article-title":"A comparison of cardiac computerized tomography and exercise stress electrocardiogram test for the investigation of stable chest pain: the clinical results of the CAPP randomized prospective trial","volume":"16","author":"McKavanagh","year":"2015","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.hjc.2025.02.003_bib8","doi-asserted-by":"crossref","first-page":"e1307","DOI":"10.4244\/EIJ-D-22-00776","article-title":"Computed tomographic angiography in coronary artery disease","volume":"18","author":"Serruys","year":"2023","journal-title":"EuroIntervention"},{"key":"10.1016\/j.hjc.2025.02.003_bib9","doi-asserted-by":"crossref","first-page":"3322","DOI":"10.1093\/eurheartj\/ehy267","article-title":"The performance of non-invasive tests to rule-in and rule-out significant coronary artery stenosis in patients with stable angina: a meta-analysis focused on post-test disease probability","volume":"39","author":"Knuuti","year":"2018","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hjc.2025.02.003_bib10","doi-asserted-by":"crossref","first-page":"2816","DOI":"10.1016\/j.jacc.2009.11.096","article-title":"Angiographic versus functional severity of coronary artery stenoses in the FAME study fractional flow reserve versus angiography in multivessel evaluation","volume":"55","author":"Tonino","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hjc.2025.02.003_bib11","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1016\/j.jacc.2006.05.080","article-title":"Relationship between noninvasive coronary angiography with multi-slice computed tomography and myocardial perfusion imaging","volume":"48","author":"Schuijf","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hjc.2025.02.003_bib12","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1093\/eurheartj\/eht488","article-title":"Computed tomography angiography and perfusion to assess coronary artery stenosis causing perfusion defects by single photon emission computed tomography: the CORE320 study","volume":"35","author":"Rochitte","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hjc.2025.02.003_bib13","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jcmg.2021.07.021","article-title":"Dynamic myocardial perfusion CT for the detection of hemodynamically significant coronary artery disease","volume":"15","author":"Nous","year":"2022","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.hjc.2025.02.003_bib14","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1016\/j.jcmg.2017.10.010","article-title":"Comprehensive cardiac CT with myocardial perfusion imaging versus functional testing in suspected coronary artery disease: the multicenter, randomized CRESCENT-II trial","volume":"11","author":"Lubbers","year":"2018","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.hjc.2025.02.003_bib15","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1148\/radiol.13112739","article-title":"Stress myocardial perfusion: imaging with multidetector CT","volume":"270","author":"Rossi","year":"2014","journal-title":"Radiology"},{"key":"10.1016\/j.hjc.2025.02.003_bib16","doi-asserted-by":"crossref","first-page":"2320","DOI":"10.1161\/CIRCULATIONAHA.116.024360","article-title":"Prognostic value of noninvasive cardiovascular testing in patients with stable chest pain: insights from the PROMISE trial (Prospective multicenter imaging study for evaluation of chest pain)","volume":"135","author":"Hoffmann","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.hjc.2025.02.003_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.jacc.2019.07.085","article-title":"Guiding therapy by coronary CT angiography improves outcomes in patients with stable chest pain","volume":"74","author":"Adamson","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hjc.2025.02.003_bib18","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/j.jacc.2023.04.003","article-title":"2023 AHA\/ACC\/ACCP\/ASPC\/NLA\/PCNA guideline for the management of patients with chronic coronary disease: a report of the American heart association\/American College of cardiology Joint Committee on clinical practice guidelines","volume":"82","author":"Virani","year":"2023","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hjc.2025.02.003_bib19","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0140-6736(17)32714-9","article-title":"Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial","volume":"391","author":"Al-Lamee","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.hjc.2025.02.003_bib20","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1056\/NEJMoa1915922","article-title":"Initial invasive or conservative strategy for stable coronary disease","volume":"382","author":"Maron","year":"2020","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hjc.2025.02.003_bib21","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1038\/nrcardio.2017.131","article-title":"Expert consensus document: a 'diamond' approach to personalized treatment of angina","volume":"15","author":"Ferrari","year":"2018","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.hjc.2025.02.003_bib22","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.ijcard.2016.06.150","article-title":"Medical treatment of stable angina: a tailored therapeutic approach","volume":"220","author":"Manolis","year":"2016","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.hjc.2025.02.003_bib23","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.ejim.2021.08.003","article-title":"State of the art approach to managing angina and ischemia: tailoring treatment to the evidence","volume":"92","author":"Manolis","year":"2021","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.hjc.2025.02.003_bib24","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.ejim.2019.12.012","article-title":"The ESC 2019 CCS guidelines: have we left our patients and scientific evidence behind?","volume":"72","author":"Manolis","year":"2020","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.hjc.2025.02.003_bib25","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1056\/NEJMoa2401479","article-title":"REDUCE-AMI Investigators. Beta-blockers after myocardial infarction and preserved ejection fraction","volume":"390","author":"Yndigegn","year":"2024","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hjc.2025.02.003_bib26","doi-asserted-by":"crossref","DOI":"10.1056\/NEJMoa2404204","article-title":"ABYSS Investigators of the ACTION Study Group. Beta-blocker interruption or continuation after myocardial infarction","author":"Silvain","year":"2024","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hjc.2025.02.003_bib27","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1093\/eurheartj\/eht384","article-title":"Efficacy of the long-acting nitro vasodilator pentaerithrityl tetranitrate in patients with chronic stable angina pectoris receiving anti-anginal background therapy with beta-blockers: a 12-week, randomized, double-blind, placebo-controlled trial","volume":"35","author":"M\u00fcnzel","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hjc.2025.02.003_bib28","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/j.jacc.2006.10.074","article-title":"Once daily therapy with isosorbide-5-mononitrate causes endothelial dysfunction in humans: evidence of a free-radical-mediated mechanism","volume":"49","author":"Thomas","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hjc.2025.02.003_bib29","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.jacc.2008.04.019","article-title":"Nitrate-induced toxicity and preconditioning: a rationale for reconsidering the use of these drugs","volume":"52","author":"Gori","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hjc.2025.02.003_bib30","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.hjc.2022.12.002","article-title":"Effects of ranolazine on various outcomes in patients with stable angina: an updated meta-analysis","volume":"71","author":"Manolis","year":"2023","journal-title":"Hellenic J Cardiol"},{"key":"10.1016\/j.hjc.2025.02.003_bib31","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.ejim.2023.01.007","article-title":"How low should blood pressure be in patients with chronic coronary and cerebrovascular diseases","volume":"109","author":"Manolis","year":"2023","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.hjc.2025.02.003_bib32","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1016\/j.jacc.2009.01.037","article-title":"Efficacy of ranolazine in patients with chronic angina observations from the randomized, double-blind, placebo-controlled MERLIN-TIMI (Metabolic efficiency with ranolazine for less ischemia in non-ST-segment elevation acute coronary syndromes) 36 trial","volume":"53","author":"Wilson","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hjc.2025.02.003_bib33","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1001\/jama.297.16.1775","article-title":"Effects of ranolazine on recurrent cardiovascular events in patients with non-ST-elevation acute coronary syndromes: the MERLIN-TIMI 36 randomized trial","volume":"297","author":"Morrow","year":"2007","journal-title":"JAMA"},{"key":"10.1016\/j.hjc.2025.02.003_bib34","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/S0140-6736(15)00459-6","article-title":"Ranolazine in patients with incomplete revascularisation after percutaneous coronary intervention (RIVER-PCI): a multicentre, randomised, double-blind, placebo-controlled trial","volume":"387","author":"Weisz","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.hjc.2025.02.003_bib35","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1056\/NEJMoa1406430","article-title":"Ivabradine in stable coronary artery disease without clinical heart failure","volume":"371","author":"Fox","year":"2014","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hjc.2025.02.003_bib36","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1093\/eurheartj\/ehy504","article-title":"Anti-anginal drugs-beliefs and evidence: systematic review covering 50 years of medical treatment","volume":"40","author":"Ferrari","year":"2019","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hjc.2025.02.003_bib37","doi-asserted-by":"crossref","first-page":"2497","DOI":"10.1056\/NEJMoa1912388","article-title":"Efficacy and safety of low-dose colchicine after myocardial infarction","volume":"381","author":"Tardif","year":"2019","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hjc.2025.02.003_bib38","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1056\/NEJMoa2021372","article-title":"Colchicine in patients with chronic coronary disease","volume":"383","author":"Nidorf","year":"2020","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hjc.2025.02.003_bib39","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1093\/eurjpc\/zwab045","article-title":"Efficacy and safety of colchicine for the prevention of major cardiovascular and cerebrovascular events in patients with coronary artery disease: a systematic review and meta-analysis on 12 869 patients","volume":"28","author":"Andreis","year":"2022","journal-title":"Eur J Prev Cardiol"}],"container-title":["Hellenic Journal of Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S110996662500048X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S110996662500048X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T08:40:19Z","timestamp":1763541619000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S110996662500048X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":39,"alternative-id":["S110996662500048X"],"URL":"https:\/\/doi.org\/10.1016\/j.hjc.2025.02.003","relation":{},"ISSN":["1109-9666"],"issn-type":[{"type":"print","value":"1109-9666"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Key messages and critical approach of the 2024 guidelines of the European Society of Cardiology on chronic coronary syndromes","name":"articletitle","label":"Article Title"},{"value":"Hellenic Journal of Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hjc.2025.02.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Hellenic Society of Cardiology. Publishing services by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}