{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T05:36:50Z","timestamp":1786772210417,"version":"build-2736575974"},"reference-count":7,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","heartlungcirc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart, Lung and Circulation"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.hlc.2026.01.005","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T12:21:33Z","timestamp":1773231693000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Dabigatran Failure Leading to Stroke: A Cautionary Tale in Anticoagulant Switching Before AF Ablation Procedures"],"prefix":"10.1016","author":[{"given":"Michael R.","family":"Ward","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.hlc.2026.01.005_bib1","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s40256-022-00536-7","article-title":"Effectiveness and safety of idarucizumab for periprocedural cardiac tamponade after catheter ablation of atrial fibrillation in dabigatran recipients: a retrospective controlled study","volume":"22","author":"Huang","year":"2022","journal-title":"Am J Cardiovasc Drugs"},{"key":"10.1016\/j.hlc.2026.01.005_bib2","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1056\/NEJMoa1502000","article-title":"Idarucizamab for dabigatran reversal","volume":"373","author":"Pollack","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hlc.2026.01.005_bib3","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1056\/NEJMoa1510991","article-title":"Andexenet alfa for reversal for the Factor Xa inhibitor activity","volume":"373","author":"Siegal","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hlc.2026.01.005_bib4","doi-asserted-by":"crossref","first-page":"3314","DOI":"10.1093\/eurheartj\/ehae176","article-title":"2024 ESC Guidelines for the management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)","volume":"45","author":"Van Gelder","year":"2024","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hlc.2026.01.005_bib5","first-page":"1","article-title":"A case report for recurrent transient ischemic attacks on dabigatran for atrial fibrillation; real-world insight into treatment failure","volume":"4","author":"Huynh","year":"2020","journal-title":"Eur Heart J Case Rep"},{"key":"10.1016\/j.hlc.2026.01.005_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.dmpk.2022.100479","article-title":"Carboxylesterase-2 plays a critical role in dabigatran etexilate active metabolite formation","volume":"47","author":"Laizure","year":"2022","journal-title":"Drug Metab Pharmacokinet"},{"key":"10.1016\/j.hlc.2026.01.005_bib7","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.1016\/j.jacc.2013.02.058","article-title":"The P-glycoprotein transport system and cardiovascular drugs","volume":"61","author":"Wessler","year":"2013","journal-title":"J Am Coll Cardiol"}],"container-title":["Heart, Lung and Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1443950626000363?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1443950626000363?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T12:21:34Z","timestamp":1773231694000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1443950626000363"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":7,"alternative-id":["S1443950626000363"],"URL":"https:\/\/doi.org\/10.1016\/j.hlc.2026.01.005","relation":{},"ISSN":["1443-9506"],"issn-type":[{"value":"1443-9506","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dabigatran Failure Leading to Stroke: A Cautionary Tale in Anticoagulant Switching Before AF Ablation Procedures","name":"articletitle","label":"Article Title"},{"value":"Heart, Lung and Circulation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hlc.2026.01.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Crown Copyright \u00a9 2026 Published by Elsevier B.V. on behalf of Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}