{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T12:12:57Z","timestamp":1760184777755,"version":"build-2065373602"},"reference-count":45,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2008,10,1]],"date-time":"2008-10-01T00:00:00Z","timestamp":1222819200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,10,1]],"date-time":"2008-10-01T00:00:00Z","timestamp":1222819200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hematology\/Oncology Clinics of North America"],"published-print":{"date-parts":[[2008,10]]},"DOI":"10.1016\/j.hoc.2008.07.009","type":"journal-article","created":{"date-parts":[[2008,10,28]],"date-time":"2008-10-28T09:21:01Z","timestamp":1225185661000},"page":"965-978","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Highly Aggressive Lymphomas in Adults"],"prefix":"10.1016","volume":"22","author":[{"given":"John W.","family":"Sweetenham","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.hoc.2008.07.009_bib1","doi-asserted-by":"crossref","first-page":"3909","DOI":"10.1182\/blood.V89.11.3909","article-title":"The non-Hodgkin's Lymphoma Classification Project: A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphomas","volume":"89","year":"1997","journal-title":"Blood"},{"year":"2001","author":"Jaffe","series-title":"Tumors of the haematopoietic and lymphoid tissues. World Health Organization","key":"10.1016\/j.hoc.2008.07.009_bib2"},{"key":"10.1016\/j.hoc.2008.07.009_bib3","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1002\/pbc.20550","article-title":"Gene expression profiling reveals intrinsic differences between T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma","volume":"47","author":"Raetz","year":"2006","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.hoc.2008.07.009_bib4","doi-asserted-by":"crossref","first-page":"319","DOI":"10.7326\/0003-4819-89-3-319","article-title":"Convoluted lymphocytic lymphoma in adults: a clinicopathological entity","volume":"89","author":"Rosen","year":"1978","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.hoc.2008.07.009_bib5","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1002\/1097-0142(19811201)48:11<2347::AID-CNCR2820481102>3.0.CO;2-X","article-title":"Lymphoblastic lymphoma: a clinicopathologic study of 95 patients","volume":"48","author":"Nathwani","year":"1978","journal-title":"Cancer"},{"key":"10.1016\/j.hoc.2008.07.009_bib6","doi-asserted-by":"crossref","first-page":"2927","DOI":"10.1200\/JCO.2001.19.11.2927","volume":"19","author":"Sweetenham","year":"2001","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.hoc.2008.07.009_bib7","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1200\/JCO.1986.4.11.1628","article-title":"Treatment of lymphoblastic lymphoma in adults","volume":"4","author":"Coleman","year":"1986","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.hoc.2008.07.009_bib8","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1200\/JCO.1986.4.1.57","article-title":"Lymphoblastic lymphoma in adults","volume":"4","author":"Slater","year":"1986","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.hoc.2008.07.009_bib9","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1093\/oxfordjournals.annonc.a057692","article-title":"Lymphoblastic lymphoma in adult patients; clinicopathological features and response to intensive multi-agent chemotherapy analogous to that used in acute lymphoblastic leukemia","volume":"1","author":"Bernasconi","year":"1990","journal-title":"Ann Oncol"},{"key":"10.1016\/j.hoc.2008.07.009_bib10","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1200\/JCO.1992.10.7.1078","article-title":"Prognosis and treatment of lymphoblastic lymphoma in adults: a report on 80 patients","volume":"10","author":"Morel","year":"1992","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.hoc.2008.07.009_bib11","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1023\/A:1008202808144","article-title":"Role of induction chemotherapy and bone marrow transplantation in adult lymphoblastic lymphoma: a report on 62 patients from a single center","volume":"9","author":"Bouabdallah","year":"1998","journal-title":"Ann Oncol"},{"key":"10.1016\/j.hoc.2008.07.009_bib12","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1182\/blood.V57.1.186.186","article-title":"The chemotherapy of lymphoblastic lymphoma","volume":"57","author":"Voakes","year":"1981","journal-title":"Blood"},{"key":"10.1016\/j.hoc.2008.07.009_bib13","first-page":"3931","article-title":"Value of immunophenotype in intensively treated adult acute lymphoblastic leukemia: Cancer and Leukemia Group B study 8364","volume":"93","author":"Czuczman","year":"1999","journal-title":"Blood"},{"key":"10.1016\/j.hoc.2008.07.009_bib14","doi-asserted-by":"crossref","first-page":"11416","DOI":"10.1073\/pnas.88.24.11416","article-title":"TAL2, a helix-loop-helix gene activated by the t(7;9)(q34;q32) translocation in human T-cell leukemia","volume":"88","author":"Xia","year":"1989","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.hoc.2008.07.009_bib15","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1158\/1078-0432.CCR-07-1927","article-title":"T cell receptor genotyping and HOXA\/TLX1 expression define three T lymphoblastic lymphoma subsets which might affect clinical outcome","volume":"14","author":"Baleydier","year":"2008","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.hoc.2008.07.009_bib16","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1093\/oxfordjournals.annonc.a059214","article-title":"Short-term weekly chemotherapy followed by high dose therapy with autologous bone marrow transplantation for lymphoblastic and Burkitt's lymphomas in adult patients","volume":"6","author":"Jost","year":"1995","journal-title":"Ann Oncol"},{"key":"10.1016\/j.hoc.2008.07.009_bib17","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.1038\/sj.leu.2403095","article-title":"Adult lymphoblastic lymphoma: a retrospective analysis of 92 patients under 61 years included in the LNH87\/93 trials","volume":"17","author":"LeGouill","year":"2003","journal-title":"Leukemia"},{"key":"10.1016\/j.hoc.2008.07.009_bib18","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1038\/sj.leu.2403733","article-title":"Short intensive sequential therapy followed by autologous stem cell transplantation in adult Burkitt, Burkitt-like and lymphoblastic lymphoma","volume":"19","author":"van Imhoff","year":"2005","journal-title":"Leukemia"},{"key":"10.1016\/j.hoc.2008.07.009_bib19","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1056\/NEJM198303103081003","article-title":"Childhood non-Hodgkin's lymphoma.\u00a0The results of a randomized therapeutic trial comparing a 4-drug regimen (COMP) with a 10-drug regimen (LSA2L2)","volume":"308","author":"Anderson","year":"1983","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hoc.2008.07.009_bib20","doi-asserted-by":"crossref","first-page":"291","DOI":"10.3109\/10428199409049726","article-title":"Long-term follow up of a XCHOP-based regimen with maintenance therapy and central nervous system prophylaxis in lymphoblastic non-Hodgkin's lymphoma","volume":"15","author":"Colgan","year":"1994","journal-title":"Leuk Lymphoma"},{"key":"10.1016\/j.hoc.2008.07.009_bib21","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3109\/10428199909145953","article-title":"Non-Hodgkin's lymphoma protocols in the treatment of patients with Burkitt's lymphoma and lymphoblastic lymphoma: a report on 58 patients","volume":"36","author":"Kaiser","year":"1999","journal-title":"Leuk Lymphoma"},{"key":"10.1016\/j.hoc.2008.07.009_bib22","doi-asserted-by":"crossref","first-page":"4379","DOI":"10.1182\/blood-2002-01-0110","article-title":"Outcome of adult patients with T-lymphoblastic lymphoma treated according to protocols for acute lymphoblastic leukemia","volume":"99","author":"Hoelzer","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.hoc.2008.07.009_bib23","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1182\/blood-2003-12-4428","article-title":"Outcome with the hyper-CVAD regimens in lymphoblastic lymphoma","volume":"104","author":"Thomas","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.hoc.2008.07.009_bib24","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1038\/sj.leu.2404156","article-title":"High survival rate with the LMT-89 regimen in lymphoblastic lymphoma (LL), but not in T-cell acute lymphoblastic leukemia (T-ALL)","volume":"20","author":"Jabbour","year":"2006","journal-title":"Leukemia"},{"key":"10.1016\/j.hoc.2008.07.009_bib25","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1093\/annonc\/mdl426","article-title":"Primary therapy for adults with T-cell lymphoblastic lymphoma with hematopoietic stem-cell transplantation results in favorable outcomes","volume":"18","author":"Song","year":"2007","journal-title":"Ann Oncol"},{"key":"10.1016\/j.hoc.2008.07.009_bib26","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1200\/JCO.2005.02.2707","article-title":"Impact of cranial radiotherapy on central nervous system prophylaxis in children and adolescents with central nervous system-negative stage III or IV lymphoblastic lymphoma","volume":"24","author":"Burkhardt","year":"2006","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.hoc.2008.07.009_bib27","doi-asserted-by":"crossref","first-page":"2738","DOI":"10.1002\/cncr.10552","article-title":"The role of local radiation therapy for mediastinal disease for adults with T-cell lymphoblastic lymphoma","volume":"94","author":"Dabaja","year":"2002","journal-title":"Cancer"},{"key":"10.1016\/j.hoc.2008.07.009_bib28","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1200\/JCO.1994.12.7.1358","article-title":"High-dose therapy and autologous bone marrow transplantation for adult patients with lymphoblastic lymphoma: results from the European Group for Bone Marrow Transplantation","volume":"12","author":"Sweetenham","year":"1994","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.hoc.2008.07.009_bib29","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1038\/sj.bmt.1703891","article-title":"An EBMT registry matched study of allogeneic stem cell transplants for lymphoma: allogeneic transplantation\u00a0is associated with a lower relapse rate but a higher procedure-related mortality rate than autologous transplantation","volume":"8","author":"Peniket","year":"2003","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.hoc.2008.07.009_bib30","doi-asserted-by":"crossref","first-page":"2476","DOI":"10.1182\/blood-2002-05-1483","article-title":"A comparison of allogeneic and autologous bone marrow transplantation for lymphoblastic lymphoma","volume":"101","author":"Levine","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.hoc.2008.07.009_bib31","doi-asserted-by":"crossref","first-page":"5136","DOI":"10.1182\/blood-2006-11-056754","article-title":"Nelarabine induces complete remissions in adults with relapsed or refractory T-lineage acute lymphoblastic leukemia or lymphoblastic lymphoma: Cancer and Leukemia Group B Study 19801","volume":"109","author":"DeAngelo","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.hoc.2008.07.009_bib32","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1056\/NEJMoa055759","article-title":"Molecular diagnosis of Burkitt's lymphoma","volume":"354","author":"Dace","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hoc.2008.07.009_bib33","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.1056\/NEJMoa055351","article-title":"A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling","volume":"354","author":"Hummel","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hoc.2008.07.009_bib34","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1200\/JCO.1996.14.3.925","article-title":"Children and adults with small non-cleaved cell lymphoma have a similar excellent outcome when treated with the same chemotherapy regimen","volume":"14","author":"Magrath","year":"1996","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.hoc.2008.07.009_bib35","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1093\/annonc\/mdf253","article-title":"An international evaluation of CODOX-M and CODOX-M alternating with IVAC in adult Burkitt's lymphoma: results of United Kingdom Lymphoma Group LY06 study","volume":"13","author":"Mead","year":"2002","journal-title":"Ann Oncol"},{"key":"10.1016\/j.hoc.2008.07.009_bib36","first-page":"3294","article-title":"Improved treatment results in childhood B-cell neoplasms with tailored intensification of therapy: a report of the Berlin-Frankfurt-Munich NHL-BFM 90","volume":"94","author":"Reiter","year":"1999","journal-title":"Blood"},{"key":"10.1016\/j.hoc.2008.07.009_bib37","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/S0950-3536(05)80206-9","article-title":"Therapy of Burkitt and other B-cell acute lymphoblastic leukemia and lymphoma: experience with the LMB protocols of the SFOP (French Paediatric Oncology Society) in children and adults","volume":"2","author":"Patte","year":"1994","journal-title":"Baillieres Clin Haematol"},{"key":"10.1016\/j.hoc.2008.07.009_bib38","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1182\/blood.V85.3.664.bloodjournal853664","article-title":"Small non-cleaved cell lymphoma and leukemia in adults. A retrospective study of 65 adults treated with the LMB pediatric protocols","volume":"85","author":"Soussain","year":"1995","journal-title":"Blood"},{"key":"10.1016\/j.hoc.2008.07.009_bib39","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1200\/JCO.1991.9.6.941","article-title":"Effective treatment of small-noncleaved cell lymphoma with high-intensity, brief duration chemotherapy","volume":"9","author":"McMaster","year":"1991","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.hoc.2008.07.009_bib40","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1200\/JCO.1999.17.8.2461","article-title":"Hyper-CVAD program in Burkitt's type adult acute lymphoblastic leukemia","volume":"17","author":"Thomas","year":"1999","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.hoc.2008.07.009_bib41","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1002\/cncr.21776","article-title":"Chemoimmunotherapy with Hyper-CVAD plus rituximab for the treatment of adult Burkitt and Burkitt-type lymphoma or acute lymphoblastic leukemia","volume":"106","author":"Thomas","year":"2006","journal-title":"Cancer"},{"key":"10.1016\/j.hoc.2008.07.009_bib42","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1002\/cncr.20143","article-title":"Intensive chemotherapy with and without cranial radiation for Burkitt leukemia and lymphoma","volume":"100","author":"Rizzieri","year":"2004","journal-title":"Cancer"},{"key":"10.1016\/j.hoc.2008.07.009_bib43","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1200\/JCO.1996.14.9.2465","article-title":"Adult Burkitt's and Burkitt-like non-Hodgkin's lymphoma\u2014outcome for patients treated with high-dose therapy and autologous stem cell transplantation in first remission or at relapse: results from the European Group for Blood and Marrow Transplantation","volume":"14","author":"Sweetenham","year":"1996","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.hoc.2008.07.009_bib44","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1111\/j.1365-2141.2006.06080.x","article-title":"Haematopoietic stem cell transplantation as primary therapy of sporadic adult Burkitt lymphoma","volume":"133","author":"Song","year":"2006","journal-title":"Br J Haematol"},{"key":"10.1016\/j.hoc.2008.07.009_bib45","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1200\/JCO.1992.10.11.1690","article-title":"Autologous versus allogeneic bone marrow transplantation for non-Hodgkin's lymphoma: a case controlled analysis of the European Bone Marrow Transplant Group registry data","volume":"10","author":"Chopra","year":"1992","journal-title":"J Clin Oncol"}],"container-title":["Hematology\/Oncology Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889858808001056?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889858808001056?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T11:51:12Z","timestamp":1760183472000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889858808001056"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10]]},"references-count":45,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,10]]}},"alternative-id":["S0889858808001056"],"URL":"https:\/\/doi.org\/10.1016\/j.hoc.2008.07.009","relation":{},"ISSN":["0889-8588"],"issn-type":[{"type":"print","value":"0889-8588"}],"subject":[],"published":{"date-parts":[[2008,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Highly Aggressive Lymphomas in Adults","name":"articletitle","label":"Article Title"},{"value":"Hematology\/Oncology Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hoc.2008.07.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}