{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T08:41:36Z","timestamp":1773304896126,"version":"3.50.1"},"reference-count":21,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Homeopathy"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:p>Objective: Observational, prospective study to describe the homeopathic management of premenstrual syndrome (PMS) by a group of French physicians.<\/jats:p><jats:p>Method: Women with PMS for &gt;3 months were prescribed individualized homeopathic treatment. The intensity of 10 clinical symptoms of PMS was scored individually at inclusion and at a 3\u20136 month follow-up visit: absent = 0, mild = 1, moderate = 2, severe = 3. Total symptom score (range: 0\u201330) was calculated and compared for each patient at inclusion and at follow-up. PMS impact on daily activities (quality of life, QoL) was compared at inclusion and follow-up as: none, mild, moderate, severe, very severe.<\/jats:p><jats:p>Results: Twenty-three women were prescribed homeopathic treatment only (mean age: 39.7 years). Folliculinum (87%) was the most frequently prescribed homeopathic medicine followed by Lachesis mutus (52.2%). The most common PMS symptoms (moderate or severe) at inclusion were: irritability, aggression and tension (87%), mastodynia (78.2%) and weight gain and abdominal bloating (73.9%); and the most common symptoms at follow-up were: irritability, aggression and tension (39.1%), weight gain and abdominal bloating (26.1%) and mastodynia (17.4%). Mean global score for symptom intensity was 13.7 at inclusion and 6.3 at follow-up. The mean decrease in score (7.4) was statistically significant (p &lt; 0.0001). Twenty-one women reported that their QoL also improved significantly (91.3%; p &lt; 0.0001).<\/jats:p><jats:p>Conclusions: Homeopathic treatment was well tolerated and seemed to have a positive impact on PMS symptoms. Folliculinum was the most frequent homeopathic medicine prescribed. There appears to be scope for a properly designed, randomized, placebo-controlled trial to investigate the efficacy of individual homeopathic medicines in PMS.<\/jats:p>","DOI":"10.1016\/j.homp.2012.10.004","type":"journal-article","created":{"date-parts":[[2013,1,4]],"date-time":"2013-01-04T05:17:57Z","timestamp":1357276677000},"page":"59-65","source":"Crossref","is-referenced-by-count":12,"title":["Homeopathic treatment of premenstrual syndrome: a case 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