{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T01:56:04Z","timestamp":1788314164595,"version":"build-2803163510"},"reference-count":41,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","hpbonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["HPB"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.hpb.2020.03.014","type":"journal-article","created":{"date-parts":[[2020,4,24]],"date-time":"2020-04-24T01:41:53Z","timestamp":1587692513000},"page":"1675-1685","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Variant anatomy of the biliary system as a cause of pancreatic and peri-ampullary cancers"],"prefix":"10.1016","volume":"22","author":[{"given":"Takashi","family":"Muraki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle D.","family":"Reid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burcin","family":"Pehlivanoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raul S.","family":"Gonzalez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aarti","family":"Sekhar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahar","family":"Memis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanette","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kee-Taek","family":"Jang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pardeep","family":"Mittal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth","family":"Cardona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Kooby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shishir","family":"Maithel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan M.","family":"Sarmiento","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bassel","family":"El-Rayes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwen","family":"Lomberk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raul A.","family":"Urrutia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Christians","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas B.","family":"Evans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volkan","family":"Adsay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.hpb.2020.03.014_bib1","first-page":"7","article-title":"Cancer statistics, 2016","volume":"66","author":"Siegel","year":"2016","journal-title":"CA A Cancer J Clin"},{"key":"10.1016\/j.hpb.2020.03.014_bib2","first-page":"394","article-title":"Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"68","author":"Bray","year":"2018","journal-title":"CA A Cancer J Clin"},{"key":"10.1016\/j.hpb.2020.03.014_bib3","doi-asserted-by":"crossref","first-page":"2634","DOI":"10.1158\/0008-5472.CAN-03-3823","article-title":"Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds","volume":"64","author":"Klein","year":"2004","journal-title":"Canc Res"},{"key":"10.1016\/j.hpb.2020.03.014_bib4","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1097\/MPA.0000000000000419","article-title":"Investigating the association between periodontal disease and risk of pancreatic cancer","volume":"45","author":"Chang","year":"2016","journal-title":"Pancreas"},{"key":"10.1016\/j.hpb.2020.03.014_bib5","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1093\/annonc\/mdx019","article-title":"Periodontal disease, edentulism, and pancreatic cancer: a meta-analysis","volume":"28","author":"Maisonneuve","year":"2017","journal-title":"Ann Oncol"},{"key":"10.1016\/j.hpb.2020.03.014_bib6","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1053\/j.gastro.2009.09.059","article-title":"History of peptic ulcer disease and pancreatic cancer risk in men","volume":"138","author":"Bao","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1016\/j.hpb.2020.03.014_bib7","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1093\/aje\/kwt322","article-title":"Gallstones, cholecystectomy, and risk of digestive system cancers","volume":"179","author":"Nogueira","year":"2014","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.hpb.2020.03.014_bib8","doi-asserted-by":"crossref","first-page":"2617","DOI":"10.1007\/s00204-016-1821-9","article-title":"Environmental risk factors for pancreatic cancer: an update","volume":"90","author":"Barone","year":"2016","journal-title":"Arch Toxicol"},{"key":"10.1016\/j.hpb.2020.03.014_bib9","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1097\/MPA.0000000000000502","article-title":"Increased risk of pancreatic cancer related to gallstones and cholecystectomy: a systematic Review and meta-analysis","volume":"45","author":"Fan","year":"2016","journal-title":"Pancreas"},{"key":"10.1016\/j.hpb.2020.03.014_bib10","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/S0039-6060(97)90101-X","article-title":"Late development of bile duct cancer after sphincteroplasty: a ten- to twenty-two-year follow-up study","volume":"121","author":"Hakamada","year":"1997","journal-title":"Surgery"},{"key":"10.1016\/j.hpb.2020.03.014_bib11","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/S0002-9610(99)00087-2","article-title":"Late bile duct cancer complicating biliary-enteric anastomosis for benign disease","volume":"177","author":"Strong","year":"1999","journal-title":"Am J Surg"},{"key":"10.1016\/j.hpb.2020.03.014_bib12","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1097\/00000658-200108000-00011","article-title":"Late development of bile duct cancer in patients who had biliary-enteric drainage for benign disease: a follow-up study of more than 1,000 patients","volume":"234","author":"Tocchi","year":"2001","journal-title":"Ann Surg"},{"key":"10.1016\/j.hpb.2020.03.014_bib13","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.1002\/1097-0142(19911115)68:10<2217::AID-CNCR2820681021>3.0.CO;2-V","article-title":"Mucosal dysplasia of the liver and the intraductal variant of peripheral cholangiocarcinoma in hepatolithiasis","volume":"68","author":"Ohta","year":"1991","journal-title":"Cancer"},{"key":"10.1016\/j.hpb.2020.03.014_bib14","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/BF00710556","article-title":"Are hepatolithiasis and cholangiocarcinoma aetiologically related? A morphological study of 12 cases of hepatolithiasis associated with cholangiocarcinoma","volume":"406","author":"Nakanuma","year":"1985","journal-title":"Virchows Arch A Pathol Anat Histopathol"},{"key":"10.1016\/j.hpb.2020.03.014_bib15","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1159\/000128169","article-title":"Cholangiocarcinoma complicating primary sclerosing cholangitis: a 24-year experience","volume":"25","author":"Morris-Stiff","year":"2008","journal-title":"Dig Surg"},{"key":"10.1016\/j.hpb.2020.03.014_bib16","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S1091-255X(99)80051-1","article-title":"Diagnosis and management of cholangiocarcinoma in primary sclerosing cholangitis","volume":"3","author":"Ahrendt","year":"1999","journal-title":"J\u00a0Gastrointest Surg"},{"key":"10.1016\/j.hpb.2020.03.014_bib17","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1111\/j.1478-3231.2008.01726.x","article-title":"Outcome and prognostic factors of 391 Japanese patients with primary sclerosing cholangitis","volume":"28","author":"Tanaka","year":"2008","journal-title":"Liver Int"},{"key":"10.1016\/j.hpb.2020.03.014_bib18","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1007\/s00534-013-0606-2","article-title":"Clinical features of pancreaticobiliary maljunction: update analysis of 2nd Japan-nationwide survey","volume":"20","author":"Morine","year":"2013","journal-title":"J\u00a0Hepatobiliary Pancreat Sci"},{"key":"10.1016\/j.hpb.2020.03.014_bib19","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s00423-008-0336-0","article-title":"Pancreaticobiliary maljunction and carcinogenesis to biliary and pancreatic malignancy","volume":"394","author":"Funabiki","year":"2009","journal-title":"Langenbeck's Arch Surg"},{"key":"10.1016\/j.hpb.2020.03.014_bib20","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1007\/s00535-012-0611-2","article-title":"Japanese clinical practice guidelines for pancreaticobiliary maljunction","volume":"47","author":"Kamisawa","year":"2012","journal-title":"J\u00a0Gastroenterol"},{"key":"10.1016\/j.hpb.2020.03.014_bib21","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3109\/00365529309096050","article-title":"Clinical evaluation of a low junction of the cystic duct","volume":"28","author":"Uetsuji","year":"1993","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.hpb.2020.03.014_bib22","first-page":"1788","article-title":"Clinical figure and problems in cholecystectomy of septal structure in the patients with low junction of the cystic duct","volume":"28","author":"Ueda","year":"1995","journal-title":"Nihon Shokakigekagakkai Zasshi"},{"key":"10.1016\/j.hpb.2020.03.014_bib23","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1007\/s00464-005-0498-6","article-title":"Low conjunction of the cystic duct with the common bile duct: does it correlate with the formation of common bile duct stones?","volume":"21","author":"Tsitouridis","year":"2007","journal-title":"Surg Endosc"},{"key":"10.1016\/j.hpb.2020.03.014_bib24","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/BF00198052","article-title":"Anatomical variation of pancreatobiliary ducts in biliary stone diseases","volume":"18","author":"Kubota","year":"1993","journal-title":"Abdom Imag"},{"key":"10.1016\/j.hpb.2020.03.014_bib25","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1136\/bmj.297.6640.31","article-title":"Does low entry of cystic duct predispose to stones in the common bile duct?","volume":"297","author":"Bornman","year":"1988","journal-title":"Br Med J"},{"key":"10.1016\/j.hpb.2020.03.014_bib26","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0016-5107(98)70354-2","article-title":"Cystic duct insertion at ampulla as a cause for acute recurrent pancreatitis","volume":"47","author":"Dodda","year":"1998","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.hpb.2020.03.014_bib27","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1148\/radiographics.21.1.g01ja093","article-title":"The cystic duct: normal anatomy and disease processes","volume":"21","author":"Turner","year":"2001","journal-title":"Radiographics"},{"key":"10.1016\/j.hpb.2020.03.014_bib28","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1097\/00042737-199612000-00015","article-title":"Gallbladder cancer with a low junction of the cystic duct or an anomalous pancreaticobiliary junction","volume":"8","author":"Uetsuji","year":"1996","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.hpb.2020.03.014_bib29","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/PAS.0000000000000357","article-title":"Clinicopathologic characteristics of 29 invasive carcinomas arising in 178 pancreatic mucinous cystic neoplasms with ovarian-type stroma: implications for management and prognosis","volume":"39","author":"Jang","year":"2015","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.hpb.2020.03.014_bib30","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1038\/modpathol.2013.241","article-title":"Morphological subclassification of intrahepatic cholangiocarcinoma: etiological, clinicopathological, and molecular features","volume":"27","author":"Liau","year":"2014","journal-title":"Mod Pathol"},{"key":"10.1016\/j.hpb.2020.03.014_bib31","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1097\/PAS.0000000000000919","article-title":"Paraduodenal pancreatitis: imaging and pathologic correlation of 47 cases elucidates distinct subtypes and the factors involved in its etiopathogenesis","volume":"41","author":"Muraki","year":"2017","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.hpb.2020.03.014_bib32","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1097\/MCG.0b013e31821bf824","article-title":"Congenital anomaly of low insertion of cystic duct: endoscopic retrograde cholangiopancreatography findings and clinical significance","volume":"45","author":"Kao","year":"2011","journal-title":"J\u00a0Clin Gastroenterol"},{"key":"10.1016\/j.hpb.2020.03.014_bib33","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1245\/s10434-016-5093-7","volume":"23","author":"Saka","year":"2016","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.hpb.2020.03.014_bib34","first-page":"683","article-title":"Pancreato-biliary maljunction associated gallbladder cancer is as common in the West as in the East, shows distinct clinicopathologic characteristics and offers an invaluable model for reflux-associated physio-chemical carcinogenesis (Abstract)","volume":"98","author":"Muraki","year":"2018","journal-title":"Lab Invest"},{"key":"10.1016\/j.hpb.2020.03.014_bib35","series-title":"Greenfield's surgery: scientific principles and practice","article-title":"Calculous biliary disease","author":"Pitt","year":"2011"},{"key":"10.1016\/j.hpb.2020.03.014_bib36","first-page":"361","article-title":"Bile metabolism and lithogenesis","volume":"94","author":"O'Connell","year":"2014","journal-title":"Surg Clin"},{"key":"10.1016\/j.hpb.2020.03.014_bib37","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1038\/nrgastro.2012.23","article-title":"The biliary tree--a reservoir of multipotent stem cells","volume":"9","author":"Cardinale","year":"2012","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.hpb.2020.03.014_bib38","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1002\/hep.26753","article-title":"Liver regeneration by stem\/progenitor cells","volume":"59","author":"Itoh","year":"2014","journal-title":"Hepatology"},{"key":"10.1016\/j.hpb.2020.03.014_bib39","first-page":"186","article-title":"Biliary tree stem\/progenitor cells in glands of extrahepatic and intraheptic bile ducts: an anatomical in situ study yielding evidence of maturational lineages","volume":"220","author":"Carpino","year":"2012","journal-title":"J\u00a0Anat"},{"key":"10.1016\/j.hpb.2020.03.014_bib40","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1001\/jama.2019.10232","article-title":"Screening for pancreatic cancer: US preventive Services Task Force reaffirmation recommendation statement","volume":"322","author":"Owens","year":"2019","journal-title":"Jama"},{"key":"10.1016\/j.hpb.2020.03.014_bib41","unstructured":"https:\/\/seer.cancer.gov\/statfacts\/html\/pancreas.html [accessed 1 March 2020]."}],"container-title":["HPB"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1365182X20300964?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1365182X20300964?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T00:29:27Z","timestamp":1761265767000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1365182X20300964"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":41,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["S1365182X20300964"],"URL":"https:\/\/doi.org\/10.1016\/j.hpb.2020.03.014","relation":{},"ISSN":["1365-182X"],"issn-type":[{"value":"1365-182X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Variant anatomy of the biliary system as a cause of pancreatic and peri-ampullary cancers","name":"articletitle","label":"Article Title"},{"value":"HPB","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hpb.2020.03.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 International Hepato-Pancreato-Biliary Association Inc. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}