{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:48:30Z","timestamp":1786740510066,"version":"build-2736575974"},"reference-count":12,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:00:00Z","timestamp":1760486400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","heartrhythmcasereports.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["HeartRhythm Case Reports"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.hrcr.2025.10.014","type":"journal-article","created":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T16:46:21Z","timestamp":1760805981000},"page":"52-57","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Torsades de pointes after doxylamine overdose: A case report"],"prefix":"10.1016","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2769-3781","authenticated-orcid":false,"given":"Mohammad Eshaq","family":"Kyhan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhaval","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.hrcr.2025.10.014_bib1","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1007\/s11606-019-05477-7","article-title":"Measurement and management of QT interval prolongation for general physicians","volume":"35","author":"Indraratna","year":"2020","journal-title":"J Gen Intern Med"},{"key":"10.1016\/j.hrcr.2025.10.014_bib2","series-title":"StatPearls","article-title":"Torsade de pointes","author":"Cohagan","year":"2025"},{"key":"10.1016\/j.hrcr.2025.10.014_bib3","article-title":"A lethal twist: torsade de pointes after an accidental overdose of doxylamine","volume":"77","author":"Tiu","year":"2021","journal-title":"J Acc"},{"key":"10.1016\/j.hrcr.2025.10.014_bib4","first-page":"1","article-title":"Long QT syndrome due to doxylamine overdose","volume":"17","author":"Chhetri","year":"2024","journal-title":"Int J Clin Case Rep Rev"},{"key":"10.1016\/j.hrcr.2025.10.014_bib5","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1310\/hpj4809-762","article-title":"Doxylamine succinate\/pyridoxine hydrochloride","volume":"48","author":"Cada","year":"2013","journal-title":"Hosp Pharm"},{"key":"10.1016\/j.hrcr.2025.10.014_bib6","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1002\/j.1552-4604.1985.tb02875.x","article-title":"The pharmacokinetics of doxylamine: use of automated gas chromatography with nitrogen-phosphorus detection","volume":"25","author":"Friedman","year":"1985","journal-title":"J Clin Pharmacol"},{"key":"10.1016\/j.hrcr.2025.10.014_bib7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0119551","article-title":"Pro-arrhythmic potential of oral antihistamines (H1): combining adverse event reports with drug utilization data across Europe","volume":"10","author":"Poluzzi","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.hrcr.2025.10.014_bib8","series-title":"StatPearls","article-title":"Doxylamine","author":"Brott","year":"2025"},{"key":"10.1016\/j.hrcr.2025.10.014_bib9","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1152\/physrev.00036.2011","article-title":"hERG K(+) channels: structure, function, and clinical significance","volume":"92","author":"Vandenberg","year":"2012","journal-title":"Physiol Rev"},{"key":"10.1016\/j.hrcr.2025.10.014_bib10","first-page":"233","article-title":"Electrolyte disorders and arrhythmogenesis","volume":"18","author":"El-Sherif","year":"2011","journal-title":"Cardiol J"},{"key":"10.1016\/j.hrcr.2025.10.014_bib11","doi-asserted-by":"crossref","first-page":"136","DOI":"10.4103\/0970-9185.173335","article-title":"Ketamine-induced QTc interval prolongation","volume":"33","author":"Singh","year":"2017","journal-title":"J Anaesthesiol Clin Pharmacol"},{"key":"10.1016\/j.hrcr.2025.10.014_bib12","series-title":"StatPearls","article-title":"Elimination half-life of drugs","author":"Hallare","year":"2025"}],"container-title":["HeartRhythm Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221402712500315X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221402712500315X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:18:34Z","timestamp":1786738714000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S221402712500315X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["S221402712500315X"],"URL":"https:\/\/doi.org\/10.1016\/j.hrcr.2025.10.014","relation":{},"ISSN":["2214-0271"],"issn-type":[{"value":"2214-0271","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Torsades de pointes after doxylamine overdose: A case report","name":"articletitle","label":"Article Title"},{"value":"HeartRhythm Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hrcr.2025.10.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Heart Rhythm Society. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}