{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T20:24:34Z","timestamp":1776975874105,"version":"3.51.4"},"reference-count":45,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,19]],"date-time":"2022-10-19T00:00:00Z","timestamp":1666137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["heartrhythmopen.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart Rhythm O2"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.hroo.2022.10.007","type":"journal-article","created":{"date-parts":[[2022,10,22]],"date-time":"2022-10-22T00:03:19Z","timestamp":1666396999000},"page":"24-33","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Invasive electrophysiological testing to predict and guide permanent pacemaker implantation after transcatheter aortic valve implantation: A meta-analysis"],"prefix":"10.1016","volume":"4","author":[{"given":"Konstantinos C.","family":"Siontis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdalla","family":"Kara Balla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong-Mei","family":"Cha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Pilgrim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romy","family":"Sweda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Roten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobias","family":"Reichlin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul A.","family":"Friedman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Windecker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2128-9205","authenticated-orcid":false,"given":"George C.M.","family":"Siontis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.hroo.2022.10.007_bib1","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.jacc.2020.11.035","article-title":"2020 ACC\/AHA guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"77","author":"Writing Committee","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hroo.2022.10.007_bib2","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1093\/eurheartj\/ehab395","article-title":"2021 ESC\/EACTS guidelines for the management of valvular heart disease","volume":"43","author":"Vahanian","year":"2022","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hroo.2022.10.007_bib3","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1093\/eurheartj\/ehv574","article-title":"The future of transcatheter aortic valve implantation","volume":"37","author":"Hamm","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hroo.2022.10.007_bib4","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.1093\/eurheartj\/ehz275","article-title":"Transcatheter aortic valve implantation vs. surgical aortic valve replacement for treatment of symptomatic severe aortic stenosis: an updated meta-analysis","volume":"40","author":"Siontis","year":"2019","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hroo.2022.10.007_bib5","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1016\/j.jacc.2019.07.014","article-title":"Management of conduction disturbances associated with transcatheter aortic valve replacement: JACC scientific expert panel","volume":"74","author":"Rodes-Cabau","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hroo.2022.10.007_bib6","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1161\/CIRCULATIONAHA.117.028352","article-title":"Conduction disturbances after transcatheter aortic valve replacement: current status and future perspectives","volume":"136","author":"Auffret","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.hroo.2022.10.007_bib7","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.jcin.2014.07.022","article-title":"Predictors and clinical outcomes of permanent pacemaker implantation after transcatheter aortic valve replacement: the PARTNER (Placement of AoRtic TraNscathetER Valves) trial and registry","volume":"8","author":"Nazif","year":"2015","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.hroo.2022.10.007_bib8","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.jacc.2014.04.033","article-title":"Predictors of permanent pacemaker implantation in patients with severe aortic stenosis undergoing TAVR: a meta-analysis","volume":"64","author":"Siontis","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hroo.2022.10.007_bib9","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.120.020033","article-title":"Temporal incidence and predictors of high-grade atrioventricular block after transcatheter aortic valve replacement","volume":"10","author":"El-Sabawi","year":"2021","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.hroo.2022.10.007_bib10","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.pcad.2021.06.004","article-title":"Epidemiology, evaluation, and management of conduction disturbances after transcatheter aortic valve replacement","volume":"66","author":"Aymond","year":"2021","journal-title":"Prog Cardiovasc Dis"},{"key":"10.1016\/j.hroo.2022.10.007_bib11","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1136\/heartjnl-2017-312310","article-title":"New-onset arrhythmias following transcatheter aortic valve implantation: a systematic review and meta-analysis","volume":"104","author":"Siontis","year":"2018","journal-title":"Heart"},{"key":"10.1016\/j.hroo.2022.10.007_bib12","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/j.jcmg.2016.11.020","article-title":"A highly predictive risk model for pacemaker implantation after TAVR","volume":"10","author":"Maeno","year":"2017","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.hroo.2022.10.007_bib13","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"10.1016\/j.hroo.2022.10.007_bib14","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1471-2288-5-13","article-title":"Estimating the mean and variance from the median, range, and the size of a sample","volume":"5","author":"Hozo","year":"2005","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.hroo.2022.10.007_bib15","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1136\/bmj.316.7136.989","article-title":"When can odds ratios mislead?","volume":"316","author":"Davies","year":"1998","journal-title":"BMJ"},{"key":"10.1016\/j.hroo.2022.10.007_bib16","doi-asserted-by":"crossref","first-page":"f7450","DOI":"10.1136\/bmj.f7450","article-title":"Converting an odds ratio to a range of plausible relative risks for better communication of research findings","volume":"348","author":"Grant","year":"2014","journal-title":"BMJ"},{"key":"10.1016\/j.hroo.2022.10.007_bib17","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/1471-2288-14-25","article-title":"The Hartung-Knapp-Sidik-Jonkman method for random effects meta-analysis is straightforward and considerably outperforms the standard DerSimonian-Laird method","volume":"14","author":"IntHout","year":"2014","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.hroo.2022.10.007_bib18","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/s12874-015-0091-1","article-title":"Hartung-Knapp-Sidik-Jonkman approach and its modification for random-effects meta-analysis with few studies","volume":"15","author":"Rover","year":"2015","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.hroo.2022.10.007_bib19","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1002\/jrsm.1316","article-title":"A comparison of heterogeneity variance estimators in simulated random-effects meta-analyses","volume":"10","author":"Langan","year":"2019","journal-title":"Res Synth Methods"},{"key":"10.1016\/j.hroo.2022.10.007_bib20","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1002\/jrsm.1475","article-title":"On weakly informative prior distributions for the heterogeneity parameter in Bayesian random-effects meta-analysis","volume":"12","author":"Rover","year":"2021","journal-title":"Res Synth Methods"},{"key":"10.1016\/j.hroo.2022.10.007_bib21","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1161\/CIRCINTERVENTIONS.111.961649","article-title":"Atrioventricular conduction disturbance characterization in transcatheter aortic valve implantation with the CoreValve prosthesis","volume":"4","author":"Rubin","year":"2011","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.hroo.2022.10.007_bib22","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/1471-2261-12-87","article-title":"Predictive factors for pacemaker requirement after transcatheter aortic valve implantation","volume":"12","author":"Akin","year":"2012","journal-title":"BMC Cardiovasc Disord"},{"key":"10.1016\/j.hroo.2022.10.007_bib23","first-page":"305","article-title":"Electrophysiological evaluation of atrioventricular conduction disturbances in transcatheter aortic valve implantation with Edwards SAPIEN prosthesis","volume":"25","author":"Eksik","year":"2013","journal-title":"J Invasive Cardiol"},{"key":"10.1016\/j.hroo.2022.10.007_bib24","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.hrthm.2014.10.023","article-title":"Electrocardiographic and electrophysiological predictors of atrioventricular block after transcatheter aortic valve replacement","volume":"12","author":"Rivard","year":"2015","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hroo.2022.10.007_bib25","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1080\/AC.70.5.3110518","article-title":"Baseline HV-interval predicts complete AV-block secondary to transcatheter aortic valve implantation","volume":"70","author":"Shin","year":"2015","journal-title":"Acta Cardiol"},{"key":"10.1016\/j.hroo.2022.10.007_bib26","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1111\/pace.12917","article-title":"Comparison of Edwards Sapien XT versus Lotus valve devices in terms of electrophysiological study parameters in patients undergoing TAVI","volume":"39","author":"Eksik","year":"2016","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.hroo.2022.10.007_bib27","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1093\/europace\/euv137","article-title":"Permanent pacing after transcatheter aortic valve implantation of a CoreValve prosthesis as determined by electrocardiographic and electrophysiological predictors: a single-centre experience","volume":"18","author":"Kostopoulou","year":"2016","journal-title":"Europace"},{"key":"10.1016\/j.hroo.2022.10.007_bib28","first-page":"28","article-title":"Atrioventricular conduction changes after corevalve transcatheter aortic valve implantation","volume":"69","author":"Lopez-Aguilera","year":"2016","journal-title":"Rev Esp Cardiol (Engl Ed)"},{"key":"10.1016\/j.hroo.2022.10.007_bib29","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s10840-016-0218-2","article-title":"The value of electrophysiologic study in decision-making regarding the need for pacemaker implantation after TAVI","volume":"48","author":"Tovia-Brodie","year":"2017","journal-title":"J Interv Card Electrophysiol"},{"key":"10.1016\/j.hroo.2022.10.007_bib30","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.ijcard.2017.02.029","article-title":"Respective role of surface electrocardiogram and His bundle recordings to assess the risk of atrioventricular block after transcatheter aortic valve replacement","volume":"236","author":"Badenco","year":"2017","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.hroo.2022.10.007_bib31","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.1016\/j.carrev.2017.03.009","article-title":"Conduction disturbances after TAVR: Electrophysiological studies and pacemaker dependency","volume":"18","author":"Makki","year":"2017","journal-title":"Cardiovasc Revasc Med"},{"key":"10.1016\/j.hroo.2022.10.007_bib32","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/j.amjcard.2018.02.015","article-title":"Utility of invasive electrophysiology studies in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation","volume":"121","author":"Rogers","year":"2018","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.hroo.2022.10.007_bib33","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.119.014446","article-title":"Electrophysiology testing to stratify patients with left bundle branch block after transcatheter aortic valve implantation","volume":"9","author":"Knecht","year":"2020","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.hroo.2022.10.007_bib34","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/j.jcin.2020.01.215","article-title":"The utility of rapid atrial pacing immediately post-TAVR to predict the need for pacemaker implantation","volume":"13","author":"Krishnaswamy","year":"2020","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.hroo.2022.10.007_bib35","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.hrthm.2020.10.018","article-title":"Intraprocedural dynamics of cardiac conduction during transcatheter aortic valve implantation: assessment by simultaneous electrophysiological testing","volume":"18","author":"Reiter","year":"2021","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hroo.2022.10.007_bib36","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.amjcard.2021.03.014","article-title":"Electrophysiological study-guided permanent pacemaker implantation in patients with conduction disturbances following transcatheter aortic valve implantation","volume":"149","author":"Bourenane","year":"2021","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.hroo.2022.10.007_bib37","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1536\/ihj.21-145","article-title":"Bedside Electrophysiological study using a temporary pacemaker may predict recurrence of atrioventricular block after transcatheter aortic valve replacement","volume":"62","author":"Nauchi","year":"2021","journal-title":"Int Heart J"},{"key":"10.1016\/j.hroo.2022.10.007_bib38","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1111\/pace.14225","article-title":"Predictors of high-degree conduction disturbances and pacemaker implantation after transcatheter aortic valve replacement: prognostic role of the electrophysiological study","volume":"44","author":"Ferreira","year":"2021","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.hroo.2022.10.007_bib39","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2018.0088","article-title":"Association of clinical and economic outcomes with permanent pacemaker implantation after transcatheter aortic valve replacement","volume":"1","author":"Aljabbary","year":"2018","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.hroo.2022.10.007_bib40","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.120.016685","article-title":"Temporal trends in the incidence and outcomes of pacemaker implantation after transcatheter aortic valve replacement in the United States (2012-2017)","volume":"9","author":"Kawsara","year":"2020","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.hroo.2022.10.007_bib41","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1016\/j.jacc.2020.08.050","article-title":"2020 ACC expert consensus decision pathway on management of conduction disturbances in patients undergoing transcatheter aortic valve replacement: a report of the American College of Cardiology Solution Set Oversight Committee","volume":"76","author":"Lilly","year":"2020","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hroo.2022.10.007_bib42","doi-asserted-by":"crossref","first-page":"2538","DOI":"10.1016\/j.jacc.2019.02.068","article-title":"Ambulatory rhythm monitoring to detect late high-grade atrioventricular block following transcatheter aortic valve replacement","volume":"73","author":"Ream","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hroo.2022.10.007_bib43","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.118.007635","article-title":"Utility of 30-day continuous ambulatory monitoring to identify patients with delayed occurrence of atrioventricular block after transcatheter aortic valve replacement","volume":"12","author":"Tian","year":"2019","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.hroo.2022.10.007_bib44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijcard.2014.04.003","article-title":"Visualizing anatomical evidences on atrioventricular conduction system for TAVI","volume":"174","author":"Kawashima","year":"2014","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.hroo.2022.10.007_bib45","first-page":"e333","volume":"140","author":"Kusumoto","year":"2019","journal-title":"Circulation"}],"container-title":["Heart Rhythm O2"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666501822002793?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666501822002793?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T00:26:01Z","timestamp":1762993561000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666501822002793"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["S2666501822002793"],"URL":"https:\/\/doi.org\/10.1016\/j.hroo.2022.10.007","relation":{},"ISSN":["2666-5018"],"issn-type":[{"value":"2666-5018","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Invasive electrophysiological testing to predict and guide permanent pacemaker implantation after transcatheter aortic valve implantation: A meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Heart Rhythm O2","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hroo.2022.10.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Heart Rhythm Society. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}