{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:08:22Z","timestamp":1786990102336,"version":"build-2736575974"},"reference-count":44,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T00:00:00Z","timestamp":1689638400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["heartrhythmopen.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart Rhythm O2"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.hroo.2023.07.006","type":"journal-article","created":{"date-parts":[[2023,7,20]],"date-time":"2023-07-20T14:07:43Z","timestamp":1689862063000},"page":"574-580","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Speech-induced atrial tachycardia: A narrative review of putative mechanisms implicating the autonomic nervous system"],"prefix":"10.1016","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3981-8796","authenticated-orcid":false,"given":"Gabriel M.Pajares","family":"Hurtado","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John-Ross D.","family":"Clarke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre","family":"Zimerman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Maher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliana","family":"Tavares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre","family":"d\u2019Avila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.hroo.2023.07.006_bib1","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1161\/CIRCRESAHA.113.302549","article-title":"Role of the autonomic nervous system in modulating cardiac arrhythmias","volume":"114","author":"Shen","year":"2014","journal-title":"Circ Res"},{"key":"10.1016\/j.hroo.2023.07.006_bib2","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1046\/j.1540-8167.2001.00852.x","volume":"12","author":"Saoudi","year":"2001","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hroo.2023.07.006_bib3","doi-asserted-by":"crossref","first-page":"e83","DOI":"10.1056\/NEJMicm2030596","article-title":"Speech-induced atrial tachycardia","volume":"384","author":"Zimerman","year":"2021","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hroo.2023.07.006_bib4","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1007\/BF02627765","article-title":"\u00dcber einen Fall von sog. \u201cSchluck-tachykardie\u201d","volume":"50","author":"Sakai","year":"1926","journal-title":"Z Gesamte Exp Med"},{"key":"10.1016\/j.hroo.2023.07.006_bib5","first-page":"116","article-title":"A case of speech-induced supraventricular tachycardia","volume":"45","author":"Kan","year":"1981","journal-title":"Jpn Circ J"},{"key":"10.1016\/j.hroo.2023.07.006_bib6","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1378\/chest.86.5.797","article-title":"Tachyarrhythmia provoked by coughing and other stimuli","volume":"86","author":"Omori","year":"1984","journal-title":"Chest"},{"key":"10.1016\/j.hroo.2023.07.006_bib7","first-page":"S102","article-title":"Ablation of a case of speech induced atrial fibrillation","volume":"4","author":"Gallagher","year":"2007","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hroo.2023.07.006_bib8","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1016\/j.jacc.2012.04.065","article-title":"Conversational atrial tachycardia","volume":"60","author":"Fan","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hroo.2023.07.006_bib9","first-page":"828","article-title":"Cryo-balloon ablation of the right superior pulmonary vein involving the anterior right ganglionated plexus for speech and breathing induced atrial tachycardia","volume":"5","author":"Medina","year":"2013","journal-title":"J Atr Fibrillation"},{"key":"10.1016\/j.hroo.2023.07.006_bib10","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1111\/jce.12278","article-title":"Speech-induced atrial tachycardia: an unusual presentation of supraventricular tachycardia","volume":"24","author":"Memon","year":"2013","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hroo.2023.07.006_bib11","article-title":"Silence is golden: an uncommon case of vocalization-triggered atrial tachycardia","volume":"30","author":"Zucchelli","year":"2014","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.hroo.2023.07.006_bib12","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1093\/europace\/euu177","article-title":"Speech-triggered atrial tachycardia originating from the superior vena cava","volume":"16","author":"Ueno","year":"2014","journal-title":"Europace"},{"key":"10.1016\/j.hroo.2023.07.006_bib13","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.hrcr.2015.01.002","article-title":"Social anxiety provoked by speech-induced atrial tachycardia","volume":"1","author":"Khemka","year":"2015","journal-title":"HeartRhythm Case Rep"},{"key":"10.1016\/j.hroo.2023.07.006_bib14","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1536\/ihj.19-582","article-title":"Silence is golden","volume":"62","author":"Liu","year":"2021","journal-title":"Int Heart J"},{"key":"10.1016\/j.hroo.2023.07.006_bib15","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/s41569-019-0221-2","article-title":"The autonomic nervous system and cardiac arrhythmias: current concepts and emerging therapies","volume":"16","author":"Herring","year":"2019","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.hroo.2023.07.006_bib16","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1161\/CIRCULATIONAHA.106.678995","article-title":"The brain-heart connection","volume":"116","author":"Samuels","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.hroo.2023.07.006_bib17","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1113\/expphysiol.2007.041178","article-title":"Potential clinical relevance of the 'little brain' on the mammalian heart","volume":"93","author":"Armour","year":"2008","journal-title":"Exp Physiol"},{"key":"10.1016\/j.hroo.2023.07.006_bib18","doi-asserted-by":"crossref","first-page":"3911","DOI":"10.1113\/JP271870","article-title":"Clinical neurocardiology defining the value of neuroscience-based cardiovascular therapeutics","volume":"594","author":"Shivkumar","year":"2016","journal-title":"J Physiol"},{"key":"10.1016\/j.hroo.2023.07.006_bib19","series-title":"Cardiac Electrophysiology: From Cell to Bedside","first-page":"375","article-title":"Neural activity and atrial tachyarrhythmias","author":"Shen","year":"2018"},{"key":"10.1016\/j.hroo.2023.07.006_bib20","doi-asserted-by":"crossref","first-page":"149","DOI":"10.4070\/kcj.2015.45.2.149","article-title":"Cervical vagal nerve stimulation activates the stellate ganglion in ambulatory dogs","volume":"45","author":"Rhee","year":"2015","journal-title":"Korean Circ J"},{"key":"10.1016\/j.hroo.2023.07.006_bib21","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.jacc.2007.02.066","article-title":"Ganglionated plexi modulate extrinsic cardiac autonomic nerve input: effects on sinus rate, atrioventricular conduction, refractoriness, and inducibility of atrial fibrillation","volume":"50","author":"Hou","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hroo.2023.07.006_bib22","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/(SICI)1097-0185(199702)247:2<289::AID-AR15>3.0.CO;2-L","article-title":"Gross and microscopic anatomy of the human intrinsic cardiac nervous system","volume":"247","author":"Armour","year":"1997","journal-title":"Anat Rec"},{"key":"10.1016\/j.hroo.2023.07.006_bib23","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.jacc.2006.02.054","article-title":"Autonomic innervation and segmental muscular disconnections at the human pulmonary vein-atrial junction: implications for catheter ablation of atrial-pulmonary vein junction","volume":"48","author":"Tan","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hroo.2023.07.006_bib24","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.jacep.2021.10.010","article-title":"Autonomic afferent dysregulation in atrial fibrillation","volume":"8","author":"Malik","year":"2022","journal-title":"JACC Clin Electrophysiol"},{"key":"10.1016\/j.hroo.2023.07.006_bib25","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1152\/physrev.00011.2006","article-title":"Calcium and arrhythmogenesis","volume":"87","author":"Ter Keurs","year":"2007","journal-title":"Physiol Rev"},{"key":"10.1016\/j.hroo.2023.07.006_bib26","doi-asserted-by":"crossref","first-page":"2202","DOI":"10.1161\/01.CIR.98.20.2202","article-title":"Importance of refractoriness heterogeneity in the enhanced vulnerability to atrial fibrillation induction caused by tachycardia-induced atrial electrical remodeling","volume":"98","author":"Fareh","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.hroo.2023.07.006_bib27","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1161\/01.CIR.92.7.1954","article-title":"Atrial fibrillation begets atrial fibrillation. A study in awake chronically instrumented goats","volume":"92","author":"Wijffels","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.hroo.2023.07.006_bib28","doi-asserted-by":"crossref","first-page":"2355","DOI":"10.1161\/01.CIR.0000065578.00869.7C","article-title":"Reinduction of atrial fibrillation immediately after termination of the arrhythmia is mediated by late phase 3 early afterdepolarization-induced triggered activity","volume":"107","author":"Burashnikov","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.hroo.2023.07.006_bib29","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.jacc.2003.09.030","article-title":"Roles of adrenergic and cholinergic stimulation in spontaneous atrial fibrillation in dogs","volume":"43","author":"Sharifov","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hroo.2023.07.006_bib30","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1253\/circj.CJ-11-1301","article-title":"Triggered firing and atrial fibrillation in transgenic mice with selective atrial fibrosis induced by overexpression of TGF-\u03b21","volume":"76","author":"Choi","year":"2012","journal-title":"Circ J"},{"key":"10.1016\/j.hroo.2023.07.006_bib31","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.hrthm.2005.02.012","article-title":"Triggered firing in pulmonary veins initiated by in\u00a0vitro autonomic nerve stimulation","volume":"2","author":"Patterson","year":"2005","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hroo.2023.07.006_bib32","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1016\/j.jacep.2018.09.001","article-title":"Targeting the cardiac ganglionated plexi for atrial fibrillation: modulate or destroy?","volume":"4","author":"Hanna","year":"2018","journal-title":"JACC Clin Electrophysiol"},{"key":"10.1016\/j.hroo.2023.07.006_bib33","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1111\/j.1540-8167.2011.02270.x","article-title":"Efficacy of cardiac autonomic denervation for atrial fibrillation: a meta-analysis","volume":"23","author":"Zhang","year":"2012","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hroo.2023.07.006_bib34","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.130532","article-title":"Region-specific parasympathetic nerve remodeling in the left atrium contributes to creation of a vulnerable substrate for atrial fibrillation","volume":"4","author":"Gussak","year":"2019","journal-title":"JCI Insight"},{"key":"10.1016\/j.hroo.2023.07.006_bib35","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1016\/j.jacep.2018.06.012","article-title":"Targeted ganglionated plexi denervation using magnetic nanoparticles carrying calcium chloride payload","volume":"4","author":"Yu","year":"2018","journal-title":"JACC Clin Electrophysiol"},{"key":"10.1016\/j.hroo.2023.07.006_bib36","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s10840-019-00508-z","article-title":"Clinical evidence of autonomic dysfunction due to atrial fibrillation: implications for rhythm control strategy","volume":"54","author":"Malik","year":"2019","journal-title":"J Interv Card Electrophysiol"},{"issue":"Suppl A","key":"10.1016\/j.hroo.2023.07.006_bib37","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1093\/eurheartj\/15.suppl_A.9","article-title":"Paroxysmal atrial fibrillation: a disorder of autonomic tone?","volume":"15","author":"Coumel","year":"1994","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hroo.2023.07.006_bib38","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.neubiorev.2020.12.012","article-title":"Systematic review and meta-analysis of the relationship between the heartbeat-evoked potential and interoception","volume":"122","author":"Coll","year":"2021","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.hroo.2023.07.006_bib39","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/j.jacep.2022.06.019","article-title":"Attenuation of the heartbeat-evoked potential in patients with atrial fibrillation","volume":"8","author":"Kumral","year":"2022","journal-title":"JACC Clin Electrophysiol"},{"key":"10.1016\/j.hroo.2023.07.006_bib40","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1038\/nrneurol.2012.100","article-title":"The autonomic effects of deep brain stimulation--a therapeutic opportunity","volume":"8","author":"Hyam","year":"2012","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.hroo.2023.07.006_bib41","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1161\/01.CIR.0000086979.39843.7B","article-title":"Intra-atrial pressure increases rate and organization of waves emanating from the superior pulmonary veins during atrial fibrillation","volume":"108","author":"Kalifa","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.hroo.2023.07.006_bib42","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1055\/s-0038-1625403","article-title":"Investigation of the influence of swallowing, coughing and vocalization on heart rate variability with respiratory-phase domain analysis","volume":"46","author":"Kotani","year":"2007","journal-title":"Methods Inf Med"},{"key":"10.1016\/j.hroo.2023.07.006_bib43","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1111\/j.1540-8159.2007.00844.x","article-title":"Swallowing-induced atrial tachyarrhythmias: prevalence, characteristics, and the results of the radiofrequency catheter ablation","volume":"30","author":"Tada","year":"2007","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.hroo.2023.07.006_bib44","doi-asserted-by":"crossref","first-page":"2573","DOI":"10.1161\/01.CIR.95.11.2573","article-title":"Efferent vagal innervation of the canine atria and sinus and atrioventricular nodes. The third fat pad","volume":"95","author":"Chiou","year":"1997","journal-title":"Circulation"}],"container-title":["Heart Rhythm O2"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666501823001654?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666501823001654?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T00:26:45Z","timestamp":1762993605000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666501823001654"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":44,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["S2666501823001654"],"URL":"https:\/\/doi.org\/10.1016\/j.hroo.2023.07.006","relation":{},"ISSN":["2666-5018"],"issn-type":[{"value":"2666-5018","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Speech-induced atrial tachycardia: A narrative review of putative mechanisms implicating the autonomic nervous system","name":"articletitle","label":"Article Title"},{"value":"Heart Rhythm O2","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hroo.2023.07.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Heart Rhythm Society. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}