{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T13:10:42Z","timestamp":1769001042372,"version":"3.49.0"},"reference-count":17,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000222","name":"Heart and Stroke Foundation of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000222","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008207","name":"AstraZeneca Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008207","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","heartrhythmjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart Rhythm"],"published-print":{"date-parts":[[2005,3]]},"DOI":"10.1016\/j.hrthm.2004.12.021","type":"journal-article","created":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T07:45:45Z","timestamp":1109663145000},"page":"270-275","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Cost-effectiveness of physiologic pacing: Results of the Canadian Health Economic Assessment of Physiologic Pacing"],"prefix":"10.1016","volume":"2","author":[{"given":"Bernie J.","family":"O\u2019Brien","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gordon","family":"Blackhouse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ron","family":"Goeree","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeff S.","family":"Healey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin S.","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Gent","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart J.","family":"Connolly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.hrthm.2004.12.021_bib1","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1016\/0735-1097(92)90616-U","article-title":"Deleterious effects of long-term single-chamber ventricular pacing in patients with sick sinus syndrome","volume":"19","author":"Hesselson","year":"1992","journal-title":"J Am Coll Cardiol"},{"issue":"Pt 2","key":"10.1016\/j.hrthm.2004.12.021_bib2","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1111\/j.1540-8159.1990.tb06896.x","article-title":"Intrapatient comparison between chronic VVIR and DDD pacing in patients affected by high degree AV block without heart failure","volume":"13","author":"Menozzi","year":"1990","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.hrthm.2004.12.021_bib3","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1161\/01.CIR.94.3.578","article-title":"Dual-chamber versus ventricular pacing","volume":"94","author":"Connolly","year":"1996","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2004.12.021_bib4","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1016\/S0140-6736(94)90347-6","article-title":"Prospective randomised trial of atrial versus ventricular pacing in sick-sinus syndrome","volume":"344","author":"Andersen","year":"1994","journal-title":"Lancet"},{"key":"10.1016\/j.hrthm.2004.12.021_bib5","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1056\/NEJMoa013040","article-title":"Ventricular pacing or dual-chamber pacing for sinus-node dysfunction","volume":"346","author":"Lamas","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2004.12.021_bib6","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1056\/NEJM199804163381602","article-title":"Quality of life and clinical outcomes in elderly patients treated with ventricular pacing as compared with dual-chamber pacing. Pacemaker Selection in the Elderly Investigators","volume":"338","author":"Lamas","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2004.12.021_bib7","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1056\/NEJM200005113421902","article-title":"Effects of physiologic pacing versus ventricular pacing on the risk of stroke and death due to cardiovascular causes. Canadian Trial of Physiologic Pacing Investigators","volume":"342","author":"Connolly","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2004.12.021_bib8","doi-asserted-by":"crossref","first-page":"3081","DOI":"10.1161\/01.CIR.103.25.3081","article-title":"Relationship between pacemaker dependency and the effect of pacing mode on cardiovascular outcomes","volume":"103","author":"Tang","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2004.12.021_bib9","series-title":"Ontario Case Cost Project (OCCP)","year":"1995"},{"key":"10.1016\/j.hrthm.2004.12.021_bib10","series-title":"Schedule of Benefits","year":"1999"},{"key":"10.1016\/j.hrthm.2004.12.021_bib11","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1002\/(SICI)1099-1050(199707)6:4<327::AID-HEC282>3.0.CO;2-W","article-title":"Pulling cost-effectiveness analysis up by its bootstraps","author":"Briggs","year":"1997","journal-title":"Health Econ"},{"key":"10.1016\/j.hrthm.2004.12.021_bib12","doi-asserted-by":"crossref","first-page":"419","DOI":"10.2307\/2533947","article-title":"Estimating medical costs from incomplete follow-up data","volume":"53","author":"Lin","year":"1997","journal-title":"Biometrics"},{"key":"10.1016\/j.hrthm.2004.12.021_bib13","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1146\/annurev.publhealth.23.100901.140534","article-title":"Thinking outside the box","volume":"23","author":"Briggs","year":"2002","journal-title":"Annu Rev Public Health"},{"key":"10.1016\/j.hrthm.2004.12.021_bib14","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1161\/01.CIR.103.10.1416","article-title":"Cost-effectiveness of the implantable cardioverter-defibrillator","volume":"103","author":"O\u2019Brien","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2004.12.021_bib15","first-page":"473","article-title":"How attractive does a new technology have to be to warrant adoption and utilization? Tentative guidelines for using clinical and economic evaluations","volume":"146","author":"Laupacis","year":"1992","journal-title":"CMAJ"},{"key":"10.1016\/j.hrthm.2004.12.021_bib16","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1016\/S0140-6736(97)03425-9","article-title":"Long-term follow-up of patients from a randomised trial of atrial versus ventricular pacing for sick-sinus syndrome","volume":"350","author":"Andersen","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.hrthm.2004.12.021_bib17","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1111\/j.1540-8159.1996.tb03159.x","article-title":"The impact of pulse generator longevity on the long-term costs of cardiac pacing","volume":"19","author":"Gillis","year":"1996","journal-title":"Pacing Clin Electrophysiol"}],"container-title":["Heart Rhythm"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527104009051?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527104009051?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T06:35:19Z","timestamp":1761546919000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1547527104009051"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,3]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,3]]}},"alternative-id":["S1547527104009051"],"URL":"https:\/\/doi.org\/10.1016\/j.hrthm.2004.12.021","relation":{},"ISSN":["1547-5271"],"issn-type":[{"value":"1547-5271","type":"print"}],"subject":[],"published":{"date-parts":[[2005,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cost-effectiveness of physiologic pacing: Results of the Canadian Health Economic Assessment of Physiologic Pacing","name":"articletitle","label":"Article Title"},{"value":"Heart Rhythm","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hrthm.2004.12.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}