{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T12:17:46Z","timestamp":1772713066411,"version":"3.50.1"},"reference-count":24,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","heartrhythmjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart Rhythm"],"published-print":{"date-parts":[[2010,6]]},"DOI":"10.1016\/j.hrthm.2010.02.035","type":"journal-article","created":{"date-parts":[[2010,3,2]],"date-time":"2010-03-02T04:58:38Z","timestamp":1267505918000},"page":"781-785","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"title":["Congenital long QT syndrome and 2:1 atrioventricular block: An optimistic outcome in the current era"],"prefix":"10.1016","volume":"7","author":[{"given":"Peter F.","family":"Aziz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronn E.","family":"Tanel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilana J.","family":"Zelster","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert H.","family":"Pass","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tammy S.","family":"Wieand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria L.","family":"Vetter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. Lee","family":"Vogel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maully J.","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.hrthm.2010.02.035_bib1","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1161\/01.CIR.102.10.1178","article-title":"Spectrum of mutations in long-QT syndrome genes","volume":"102","author":"Splawski","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2010.02.035_bib2","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1016\/0002-8703(95)90222-8","article-title":"Infants with long-QT syndrome and 2:1 atrioventricular block","volume":"130","author":"Trippel","year":"1995","journal-title":"Am Heart J"},{"key":"10.1016\/j.hrthm.2010.02.035_bib3","article-title":"Evaluation of children with ventricular arrhythmias","volume":"42","author":"Radford","year":"1977","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.hrthm.2010.02.035_bib4","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1136\/adc.54.10.776","article-title":"Prolonged QT interval and cardiac arrhythmias in two neonates: sudden infant death syndrome in one case","volume":"54","author":"Southall","year":"1979","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.hrthm.2010.02.035_bib5","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/S0735-1097(85)80317-X","article-title":"The conduction system in patients with prolonged QT interval","volume":"6","author":"Bharati","year":"1985","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2010.02.035_bib6","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1111\/j.1540-8159.1990.tb02077.x","article-title":"Persistent functional atrioventricular block in two patients with prolonged QT intervals: elucidation of the mechanism of block","volume":"13","author":"Van Hare","year":"1990","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.hrthm.2010.02.035_bib7","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1093\/eurheartj\/12.7.838","article-title":"Prolonged QT, atrioventricular block and sudden death in the newborn: an electrophysiologic evaluation","volume":"12","author":"Saoudi","year":"1991","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hrthm.2010.02.035_bib8","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1016\/j.jacc.2003.09.049","article-title":"Long QT syndrome in neonates","volume":"43","author":"Lupoglazoff","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2010.02.035_bib9","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s10840-009-9428-1","article-title":"Long QT syndrome due to a novel mutation in SCN5A: treatment with ICD placement at 1 month and left cardiac sympathetic denervation at 3 months of age","volume":"1","author":"Silver","year":"2009","journal-title":"J Interv Card Electrophysiol"},{"key":"10.1016\/j.hrthm.2010.02.035_bib10","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1016\/0002-9149(87)90634-5","article-title":"Infants with long-QT syndrome and 2:1 atrioventricular block","volume":"60","author":"Scott","year":"1995","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.hrthm.2010.02.035_bib11","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1111\/j.1540-8167.1998.tb00096.x","article-title":"The long QT syndrome with impaired atrioventricular conduction: a malignant variant in infants","volume":"9","author":"Gorgels","year":"1998","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2010.02.035_bib12","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1016\/0735-1097(91)90560-V","article-title":"Pseudo 2:1 atrioventricular block and T wave alternans in the long QT syndromes","volume":"18","author":"Rosenbaum","year":"1991","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2010.02.035_bib13","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1161\/CIRCULATIONAHA.109.863209","article-title":"Prevalence of the congenital long-QT syndrome","volume":"120","author":"Schwartz","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2010.02.035_bib14","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1161\/01.CIR.87.6.1866","article-title":"The long QT syndrome in children","volume":"87","author":"Garson","year":"1993","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2010.02.035_bib15","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.jacc.2009.05.029","article-title":"Clinical implications for patients with long QT syndrome who experience a cardiac event during infancy","volume":"54","author":"Spazzolini","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2010.02.035_bib16","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.2174\/1381612053764823","article-title":"Specific therapy based on the genotype and cellular mechanism in inherited cardiac arrhythmias","volume":"11","author":"Shimizu","year":"2005","journal-title":"Curr Pharm Des"},{"key":"10.1016\/j.hrthm.2010.02.035_bib17","doi-asserted-by":"crossref","DOI":"10.1161\/01.CIR.84.4.1524","article-title":"Efficacy of permanent pacing in the management of high-risk patients with long QT syndrome","volume":"84","author":"Moss","year":"1991","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2010.02.035_bib18","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1111\/j.1540-8167.1999.tb00647.x","article-title":"Two-to-one block associated with the congenital long QT syndrome","volume":"10","author":"Pruvot","year":"1999","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2010.02.035_bib19","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1161\/01.CIR.97.16.1581","article-title":"Improvement of repolarization abnormalities by a K channel opener in the LQT1 form of congenital long QT syndrome","volume":"97","author":"Shimizu","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2010.02.035_bib20","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/3-540-29715-4_10","article-title":"Experimental therapy of genetic arrhythmias: disease-specific pharmacology","volume":"171","author":"Priori","year":"2006","journal-title":"Handb Exp Pharmacol"},{"key":"10.1016\/j.hrthm.2010.02.035_bib21","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1016\/j.jacc.2003.07.006","article-title":"A new oral therapy for long QT syndrome","volume":"42","author":"Etheridge","year":"2003","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2010.02.035_bib22","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1046\/j.1540-8167.2003.02949.x-i1","article-title":"A multicenter experience with novel implantable cardioverter defibrillator configurations in the pediatric and congenital heart disease population","volume":"17","author":"Stephenson","year":"2006","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2010.02.035_bib23","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1016\/S0022-5223(03)01032-8","article-title":"Single-finger subcutaneous defibrillation lead and \u201cactive can\u201d: a novel minimally invasive defibrillation configuration for implantable cardioverter-defibrillator implantation in a young child","volume":"126","author":"Madan","year":"2003","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.hrthm.2010.02.035_bib24","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.hrthm.2009.03.024","article-title":"Left cardiac sympathetic denervation for the treatment of long QT syndrome and catecholaminergic polymorphic ventricular tachycardia using video-assisted thoracic surgery","volume":"6","author":"Collura","year":"2009","journal-title":"Heart Rhythm"}],"container-title":["Heart Rhythm"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527110001815?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527110001815?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T06:42:05Z","timestamp":1761547325000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1547527110001815"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6]]},"references-count":24,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["S1547527110001815"],"URL":"https:\/\/doi.org\/10.1016\/j.hrthm.2010.02.035","relation":{},"ISSN":["1547-5271"],"issn-type":[{"value":"1547-5271","type":"print"}],"subject":[],"published":{"date-parts":[[2010,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Congenital long QT syndrome and 2:1 atrioventricular block: An optimistic outcome in the current era","name":"articletitle","label":"Article Title"},{"value":"Heart Rhythm","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hrthm.2010.02.035","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}