{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T08:06:06Z","timestamp":1791014766043,"version":"4.1.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart Rhythm"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1016\/j.hrthm.2013.07.007","type":"journal-article","created":{"date-parts":[[2013,7,11]],"date-time":"2013-07-11T15:15:21Z","timestamp":1373555721000},"page":"1368-1374","source":"Crossref","is-referenced-by-count":157,"title":["Clinical outcomes with synchronized left ventricular pacing: Analysis of the adaptive CRT trial"],"prefix":"10.1016","volume":"10","author":[{"given":"David","family":"Birnie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernd","family":"Lemke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazutaka","family":"Aonuma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry","family":"Krum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathy Lai-Fun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Gasparini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randall C.","family":"Starling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goran","family":"Milasinovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"John","family":"Gorcsan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud","family":"Houmsse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athula","family":"Abeyratne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Sambelashvili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David O.","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.hrthm.2013.07.007_bib1","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1056\/NEJMoa013168","article-title":"Cardiac resynchronization in chronic heart failure","volume":"346","author":"Abraham","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2013.07.007_bib2","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1056\/NEJMoa032423","article-title":"Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure","volume":"350","author":"Bristow","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2013.07.007_bib3","doi-asserted-by":"crossref","first-page":"3273","DOI":"10.1161\/01.CIR.96.10.3273","article-title":"Evaluation of different ventricular pacing sites in patients with severe heart failure: results of an acute hemodynamic study","volume":"96","author":"Blanc","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2013.07.007_bib4","doi-asserted-by":"crossref","first-page":"2993","DOI":"10.1161\/01.CIR.99.23.2993","article-title":"Effect of pacing chamber and atrioventricular delay on acute systolic function of paced patients with congestive heart failure. The Pacing Therapies for Congestive Heart Failure Study Group. The Guidant Congestive Heart Failure Research Group","volume":"99","author":"Auricchio","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2013.07.007_bib5","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.1161\/CIRCULATIONAHA.106.634444","article-title":"Reduced ventricular volumes and improved systolic function with cardiac resynchronization therapy: a randomized trial comparing simultaneous biventricular pacing, sequential biventricular pacing, and left ventricular pacing","volume":"115","author":"Rao","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2013.07.007_bib6","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1016\/j.ahj.2010.03.008","article-title":"A randomized double-blind comparison of biventricular versus left ventricular stimulation for cardiac resynchronization therapy: the Biventricular versus Left Univentricular Pacing with ICD Back-up in Heart Failure Patients (B-LEFT HF) trial","volume":"159","author":"Boriani","year":"2010","journal-title":"Am Heart J"},{"key":"10.1016\/j.hrthm.2013.07.007_bib7","doi-asserted-by":"crossref","first-page":"2874","DOI":"10.1161\/CIRCULATIONAHA.111.032904","article-title":"Left ventricular versus simultaneous biventricular pacing in patients with heart failure and a QRS complex \u2265120 milliseconds","volume":"124","author":"Thibault","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2013.07.007_bib8","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1161\/01.CIR.99.12.1567","article-title":"Improved left ventricular mechanics from acute VDD pacing in patients with dilated cardiomyopathy and ventricular conduction delay","volume":"99","author":"Kass","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2013.07.007_bib9","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.1016\/j.jacc.2005.02.098","article-title":"The hemodynamic effect of intrinsic conduction during left ventricular pacing as compared to biventricular pacing","volume":"46","author":"van Gelder","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2013.07.007_bib10","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1111\/j.1540-8159.2005.00181.x","article-title":"Invasive optimization of cardiac resynchronization therapy: role of sequential biventricular and left ventricular pacing","volume":"28","author":"Kurzidim","year":"2005","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.hrthm.2013.07.007_bib11","doi-asserted-by":"crossref","first-page":"H968","DOI":"10.1152\/ajpheart.00641.2005","article-title":"Tailoring cardiac resynchronization therapy using interventricular asynchrony. Validation of a simple model","volume":"290","author":"Verbeek","year":"2006","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.hrthm.2013.07.007_bib12","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.jcmg.2009.12.017","article-title":"RV electrical activation in heart failure during right, left, and biventricular pacing","volume":"3","author":"Varma","year":"2010","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.hrthm.2013.07.007_bib13","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1111\/j.1540-8167.2007.00788.x","article-title":"Avoidance of right ventricular pacing in cardiac resynchronization therapy improves right ventricular hemodynamics in heart failure patients","volume":"18","author":"Lee","year":"2007","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2013.07.007_bib14","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/j.ahj.2012.02.007","article-title":"A novel algorithm for individualized cardiac resynchronization therapy: rationale and design of the adaptive cardiac resynchronization therapy trial","volume":"163","author":"Krum","year":"2012","journal-title":"Am Heart J"},{"key":"10.1016\/j.hrthm.2013.07.007_bib15","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1093\/europace\/eur146","article-title":"Adjusting the timing of left-ventricular pacing using electrocardiogram and device electrograms","volume":"13","author":"Khaykin","year":"2011","journal-title":"Europace"},{"key":"10.1016\/j.hrthm.2013.07.007_bib16","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1016\/j.hrthm.2012.07.009","article-title":"Investigation of a novel algorithm for synchronized left-ventricular pacing and ambulatory optimization of cardiac resynchronization therapy: results of the adaptive CRT trial","volume":"9","author":"Martin","year":"2012","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2013.07.007_bib17","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.echo.2008.01.003","article-title":"Echocardiography for cardiac resynchronization therapy: recommendations for performance and reporting--a report from the American Society of Echocardiography Dyssynchrony Writing Group endorsed by the Heart Rhythm Society","volume":"21","author":"Gorcsan","year":"2008","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.hrthm.2013.07.007_bib18","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.ahj.2006.04.004","volume":"152","author":"Gasparini","year":"2006","journal-title":"Am Heart J"},{"key":"10.1016\/j.hrthm.2013.07.007_bib19","doi-asserted-by":"crossref","first-page":"S62","DOI":"10.1016\/j.cardfail.2006.06.213","article-title":"The Significance of PR Interval in LV Only Pacing for Cardiac Resynchronization","volume":"12","author":"Husby","year":"2006","journal-title":"Journal of Cardiac Failure"},{"key":"10.1016\/j.hrthm.2013.07.007_bib20","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1111\/j.1540-8167.2010.01807.x","article-title":"Optimal atrioventricular delay in CRT patients can be approximated using surface electrocardiography and device electrograms","volume":"21","author":"Jones","year":"2010","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2013.07.007_bib21","doi-asserted-by":"crossref","first-page":"S236","DOI":"10.1111\/j.1540-8159.2008.02294.x","article-title":"Optimization of AV and VV delays in the real-world CRT patient population: an international survey on current clinical practice","volume":"32","author":"Gras","year":"2009","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.hrthm.2013.07.007_bib22","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.hrthm.2011.07.038","article-title":"Does cardiac resynchronization therapy provide unrecognized benefit in patients with prolonged PR intervals? The impact of restoring atrioventricular synchrony: an analysis from the COMPANION Trial","volume":"9","author":"Olshansky","year":"2012","journal-title":"Heart Rhythm"}],"container-title":["Heart Rhythm"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527113007327?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527113007327?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,14]],"date-time":"2018-10-14T13:00:17Z","timestamp":1539522017000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1547527113007327"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":22,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["S1547527113007327"],"URL":"https:\/\/doi.org\/10.1016\/j.hrthm.2013.07.007","relation":{},"ISSN":["1547-5271"],"issn-type":[{"value":"1547-5271","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9]]}}}