{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T13:34:04Z","timestamp":1768916044255,"version":"3.49.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["K23HL098370"],"award-info":[{"award-number":["K23HL098370"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["L30HL093896"],"award-info":[{"award-number":["L30HL093896"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002112","name":"A.P. Giannini Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002112","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","heartrhythmjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart Rhythm"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1016\/j.hrthm.2014.07.007","type":"journal-article","created":{"date-parts":[[2014,7,8]],"date-time":"2014-07-08T15:20:47Z","timestamp":1404832847000},"page":"2167-2175","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"title":["Coronary sinus biomarker sampling compared to peripheral venous blood for predicting outcomes in patients with severe heart failure undergoing cardiac resynchronization therapy: The BIOCRT study"],"prefix":"10.1016","volume":"11","author":[{"given":"Quynh A.","family":"Truong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James L.","family":"Januzzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jackie","family":"Szymonifka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wai-ee","family":"Thai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bryan","family":"Wai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zachary","family":"Lavender","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umesh","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan M.","family":"Sandoval","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zachary S.","family":"Grunau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandeep","family":"Basnet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adefolakemi","family":"Babatunde","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olujimi A.","family":"Ajijola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James K.","family":"Min","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jagmeet P.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.hrthm.2014.07.007_bib1","doi-asserted-by":"crossref","first-page":"e69","DOI":"10.1161\/CIRCULATIONAHA.106.179918","article-title":"Heart disease and stroke statistics\u20142007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee","volume":"115","author":"Rosamond","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2014.07.007_bib2","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.jacc.2007.05.014","article-title":"Measurement of the interleukin family member ST2 in patients with acute dyspnea: results from the PRIDE (Pro-Brain Natriuretic Peptide Investigation of Dyspnea in the Emergency Department) study","volume":"50","author":"Januzzi","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2014.07.007_bib3","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1016\/j.jacc.2008.07.042","article-title":"Characteristics of the novel interleukin family biomarker ST2 in patients with acute heart failure","volume":"52","author":"Rehman","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2014.07.007_bib4","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1016\/j.jacc.2006.03.061","article-title":"Utility of amino-terminal pro-brain natriuretic peptide, galectin-3, and apelin for the evaluation of patients with acute heart failure","volume":"48","author":"van Kimmenade","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2014.07.007_bib5","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1056\/NEJMoa013168","article-title":"Cardiac resynchronization in chronic heart failure","volume":"346","author":"Abraham","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2014.07.007_bib6","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1056\/NEJMoa050496","article-title":"The effect of cardiac resynchronization on morbidity and mortality in heart failure","volume":"352","author":"Cleland","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2014.07.007_bib7","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1056\/NEJMoa032423","article-title":"Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure","volume":"350","author":"Bristow","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2014.07.007_bib8","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1016\/S0735-1097(02)02528-7","volume":"40","author":"Gregoratos","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2014.07.007_bib9","doi-asserted-by":"crossref","first-page":"2256","DOI":"10.1093\/eurheartj\/ehm305","article-title":"Guidelines for cardiac pacing and cardiac resynchronization therapy: the task force for cardiac pacing and cardiac resynchronization therapy of the European Society of Cardiology. Developed in collaboration with the European Heart Rhythm Association","volume":"28","author":"Vardas","year":"2007","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hrthm.2014.07.007_bib10","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.1016\/j.jacc.2005.09.019","article-title":"Cardiac resynchronization therapy, Part 1: issues before device implantation","volume":"46","author":"Bax","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2014.07.007_bib11","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.1016\/j.jacc.2005.09.020","article-title":"Cardiac resynchronization therapy, Part 2: issues during and after device implantation and unresolved questions","volume":"46","author":"Bax","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2014.07.007_bib12","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1016\/j.jacc.2011.03.072","article-title":"Use of amino-terminal pro-B-type natriuretic peptide to guide outpatient therapy of patients with chronic left ventricular systolic dysfunction","volume":"58","author":"Januzzi","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2014.07.007_bib13","doi-asserted-by":"crossref","first-page":"200","DOI":"10.3909\/ricm0624","article-title":"Galectin-3: a novel blood test for the evaluation and management of patients with heart failure","volume":"12","author":"McCullough","year":"2011","journal-title":"Rev Cardiovasc Med"},{"key":"10.1016\/j.hrthm.2014.07.007_bib14","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1161\/CIRCHEARTFAILURE.110.958223","article-title":"High-sensitivity ST2 for prediction of adverse outcomes in chronic heart failure","volume":"4","author":"Ky","year":"2011","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.hrthm.2014.07.007_bib15","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1054\/jcaf.2001.25652","article-title":"Proposal for a new clinical end point to evaluate the efficacy of drugs and devices in the treatment of chronic heart failure","volume":"7","author":"Packer","year":"2001","journal-title":"J Card Fail"},{"key":"10.1016\/j.hrthm.2014.07.007_bib16","doi-asserted-by":"crossref","first-page":"2148","DOI":"10.1056\/NEJMra0800239","article-title":"Biomarkers in heart failure","volume":"358","author":"Braunwald","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2014.07.007_bib17","first-page":"e240","article-title":"2013 ACCF\/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines","volume":"128","author":"Yancy","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2014.07.007_bib18","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1161\/01.CIR.0000047274.66749.FE","article-title":"Identification of serum soluble ST2 receptor as a novel heart failure biomarker","volume":"107","author":"Weinberg","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2014.07.007_bib19","doi-asserted-by":"crossref","first-page":"2186","DOI":"10.1161\/01.CIR.0000127958.21003.5A","article-title":"Serum levels of the interleukin-1 receptor family member ST2 predict mortality and clinical outcome in acute myocardial infarction","volume":"109","author":"Shimpo","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2014.07.007_bib20","doi-asserted-by":"crossref","first-page":"3121","DOI":"10.1161\/01.CIR.0000147181.65298.4D","article-title":"Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction","volume":"110","author":"Sharma","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2014.07.007_bib21","doi-asserted-by":"crossref","first-page":"60","DOI":"10.3109\/07853890.2010.538080","article-title":"Predictive value of plasma galectin-3 levels in heart failure with reduced and preserved ejection fraction","volume":"43","author":"de Boer","year":"2011","journal-title":"Ann Med"},{"key":"10.1016\/j.hrthm.2014.07.007_bib22","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1093\/eurjhf\/hfq091","article-title":"Galectin-3, cardiac structure and function, and long-term mortality in patients with acutely decompensated heart failure","volume":"12","author":"Shah","year":"2010","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.hrthm.2014.07.007_bib23","doi-asserted-by":"crossref","first-page":"2961","DOI":"10.1161\/01.CIR.0000038705.69871.D9","article-title":"Expression and regulation of ST2, an interleukin-1 receptor family member, in cardiomyocytes and myocardial infarction","volume":"106","author":"Weinberg","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2014.07.007_bib24","doi-asserted-by":"crossref","first-page":"2174","DOI":"10.1016\/j.jacc.2009.07.041","article-title":"Soluble ST2 for predicting sudden cardiac death in patients with chronic heart failure and left ventricular systolic dysfunction","volume":"54","author":"Pascual-Figal","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2014.07.007_bib25","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1093\/eurjhf\/hfr047","article-title":"Soluble ST2, high-sensitivity troponin T- and N-terminal pro-B-type natriuretic peptide: complementary role for risk stratification in acutely decompensated heart failure","volume":"13","author":"Pascual-Figal","year":"2011","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.hrthm.2014.07.007_bib26","first-page":"391","article-title":"Neurohormonal and inflammatory markers as predictors of short-term outcome in patients with heart failure and cardiac resynchronization therapy","volume":"8","author":"Glick","year":"2006","journal-title":"Isr Med Assoc J"},{"key":"10.1016\/j.hrthm.2014.07.007_bib27","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1093\/eurheartj\/ehp210","article-title":"Relationships between cardiac resynchronization therapy and N-terminal pro-brain natriuretic peptide in patients with heart failure and markers of cardiac dyssynchrony: an analysis from the Cardiac Resynchronization in Heart Failure (CARE-HF) study","volume":"30","author":"Berger","year":"2009","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hrthm.2014.07.007_bib28","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1161\/CIRCHEARTFAILURE.112.000174","article-title":"Brain natriuretic peptide and cardiac resynchronization therapy in patients with mildly symptomatic heart failure","volume":"6","author":"Brenyo","year":"2013","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.hrthm.2014.07.007_bib29","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1093\/eurjhf\/hfr151","article-title":"Association of galectin-3 and fibrosis markers with long-term cardiovascular outcomes in patients with heart failure, left ventricular dysfunction, and dyssynchrony: insights from the CARE-HF (Cardiac Resynchronization in Heart Failure) trial","volume":"14","author":"Lopez-Andres","year":"2012","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.hrthm.2014.07.007_bib30","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1093\/eurheartj\/ehs107","article-title":"Multidisciplinary care of patients receiving cardiac resynchronization therapy is associated with improved clinical outcomes","volume":"33","author":"Altman","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hrthm.2014.07.007_bib31","first-page":"515","article-title":"Multicentre evaluation of a second generation point-of-care assay with an extended range for the determination of N-terminal pro-brain natriuretic peptide","volume":"58","author":"Jorgensen","year":"2012","journal-title":"Clin Lab"},{"key":"10.1016\/j.hrthm.2014.07.007_bib32","doi-asserted-by":"crossref","first-page":"831","DOI":"10.7754\/Clin.Lab.2012.120418","article-title":"Measurement Nt-proBNP circulating concentrations in heart failure patients with a new point-of-care assay","volume":"59","author":"Lepoutre","year":"2013","journal-title":"Clin Lab"},{"key":"10.1016\/j.hrthm.2014.07.007_bib33","doi-asserted-by":"crossref","first-page":"789","DOI":"10.2217\/bmm.12.67","article-title":"Equal performance of novel N-terminal proBNP (Cardiac proBNP(R)) and established BNP (Triage BNP(R)) point-of-care tests","volume":"6","author":"Jungbauer","year":"2012","journal-title":"Biomark Med"},{"key":"10.1016\/j.hrthm.2014.07.007_bib34","unstructured":"http:\/\/investor.bg-medicine.com\/releasedetail.cfm?ReleaseID=535701. Accessed December 31, 2013."},{"key":"10.1016\/j.hrthm.2014.07.007_bib35","unstructured":"http:\/\/www.criticaldiagnostics.com\/US\/news\/news-101513.html. Accessed December 31, 2013."}],"container-title":["Heart Rhythm"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527114007437?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527114007437?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T06:46:59Z","timestamp":1761547619000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1547527114007437"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12]]},"references-count":35,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["S1547527114007437"],"URL":"https:\/\/doi.org\/10.1016\/j.hrthm.2014.07.007","relation":{},"ISSN":["1547-5271"],"issn-type":[{"value":"1547-5271","type":"print"}],"subject":[],"published":{"date-parts":[[2014,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Coronary sinus biomarker sampling compared to peripheral venous blood for predicting outcomes in patients with severe heart failure undergoing cardiac resynchronization therapy: The BIOCRT study","name":"articletitle","label":"Article Title"},{"value":"Heart Rhythm","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hrthm.2014.07.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}