{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T15:51:09Z","timestamp":1790178669678,"version":"4.1.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","heartrhythmjournal.com","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart Rhythm"],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.1016\/j.hrthm.2015.10.006","type":"journal-article","created":{"date-parts":[[2015,10,16]],"date-time":"2015-10-16T10:33:41Z","timestamp":1444991621000},"page":"399-406","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":58,"title":["Biatrial linear ablation in sustained nonpermanent AF: Results of the substrate modification with ablation and antiarrhythmic drugs in nonpermanent atrial fibrillation (SMAN-PAF) trial"],"prefix":"10.1016","volume":"13","author":[{"given":"Gareth J.","family":"Wynn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep","family":"Panikker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maureen","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Hall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Waktare","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vias","family":"Markides","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wajid","family":"Hussain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tushar","family":"Salukhe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Modi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Jarman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David G.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Snowdon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derick","family":"Todd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhiraj","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.hrthm.2015.10.006_bib1","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1093\/eurheartj\/ehq278","article-title":"Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC)","volume":"31","author":"Camm","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hrthm.2015.10.006_bib2","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1001\/jama.1994.03510350050036","article-title":"Independent risk factors for atrial fibrillation in a population-based cohort: the Framingham Heart Study","volume":"271","author":"Benjamin","year":"1994","journal-title":"JAMA"},{"key":"10.1016\/j.hrthm.2015.10.006_bib3","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1046\/j.1540-8167.2003.02468.x","article-title":"Efficacy and safety of targeted focal ablation versus PV isolation assisted by magnetic electroanatomic mapping","volume":"14","author":"Marchlinski","year":"2003","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2015.10.006_bib4","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1046\/j.1540-8167.2004.03503.x","article-title":"Efficacy and safety of segmental ostial versus circumferential extra-ostial pulmonary vein isolation for atrial fibrillation","volume":"15","author":"Mansour","year":"2004","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2015.10.006_bib5","first-page":"142","article-title":"Pulmonary vein isolation alone in patients with persistent atrial fibrillation: an ablation strategy facilitated by antiarrhythmic drug induced reverse remodeling","volume":"22","author":"Khan","year":"2011","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2015.10.006_bib6","doi-asserted-by":"crossref","first-page":"2871","DOI":"10.1093\/eurheartj\/ehl093","article-title":"Substrate modification combined with pulmonary vein isolation improves outcome of catheter ablation in patients with persistent atrial fibrillation: a prospective randomized comparison","volume":"27","author":"Willems","year":"2006","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hrthm.2015.10.006_bib7","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1111\/j.1540-8167.2010.01755.x","article-title":"The impact of age on the electroanatomical characteristics and outcome of catheter ablation in patients with atrial fibrillation","volume":"21","author":"Tuan","year":"2010","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2015.10.006_bib8","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1111\/j.1540-8167.2011.02125.x","article-title":"Atrial electrical and structural changes associated with longstanding hypertension in humans: implications for the substrate for atrial fibrillation","volume":"22","author":"Medi","year":"2011","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2015.10.006_bib9","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/j.1540-8167.2009.01653.x","article-title":"A prospective study evaluating the role of obesity and obstructive sleep apnea for outcomes after catheter ablation of atrial fibrillation","volume":"21","author":"Chilukuri","year":"2010","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2015.10.006_bib10","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1016\/j.amjcard.2010.07.038","article-title":"Atrial substrate properties and outcome of catheter ablation in patients with paroxysmal atrial fibrillation associated with diabetes mellitus or impaired fasting glucose","volume":"106","author":"Chao","year":"2010","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.hrthm.2015.10.006_bib11","doi-asserted-by":"crossref","first-page":"2803","DOI":"10.1093\/eurheartj\/ehm358","article-title":"Outcome parameters for trials in atrial fibrillation: executive summary","volume":"28","author":"Kirchhof","year":"2007","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hrthm.2015.10.006_bib12","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.hrthm.2011.12.016","article-title":"2012 HRS\/EHRA\/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design","volume":"9","author":"Calkins","year":"2012","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2015.10.006_bib13","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1111\/j.1540-8167.2009.01603.x","article-title":"Uninterrupted warfarin for periprocedural anticoagulation in catheter ablation of typical atrial flutter: a safe and cost-effective strategy","volume":"21","author":"Finlay","year":"2010","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2015.10.006_bib14","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.1540-8167.2010.01910.x","article-title":"Catheter ablation for atrial fibrillation on uninterrupted warfarin: can it be done without echo guidance?","volume":"22","author":"Page","year":"2011","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2015.10.006_bib15","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1136\/hrt.2005.066969","article-title":"Catheter ablation of permanent atrial fibrillation: medium term results","volume":"92","author":"Earley","year":"2006","journal-title":"Heart"},{"key":"10.1016\/j.hrthm.2015.10.006_bib16","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1111\/j.1540-8167.2006.00594.x","article-title":"The impact of CT image integration into an electroanatomic mapping system on clinical outcomes of catheter ablation of atrial fibrillation","volume":"17","author":"Kistler","year":"2006","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2015.10.006_bib17","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1093\/europace\/euq107","volume":"12","author":"Caponi","year":"2010","journal-title":"Europace"},{"key":"10.1016\/j.hrthm.2015.10.006_bib18","doi-asserted-by":"crossref","first-page":"2355","DOI":"10.1161\/01.CIR.0000095796.45180.88","article-title":"Catheter ablation for paroxysmal atrial fibrillation: segmental pulmonary vein ostial ablation versus left atrial ablation","volume":"108","author":"Oral","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2015.10.006_bib19","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1093\/eurheartj\/ehs253","article-title":"2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation: developed with the special contribution of the European Heart Rhythm Association","volume":"33","author":"Camm","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hrthm.2015.10.006_bib20","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1161\/CIRCEP.108.774885","article-title":"Long-term clinical results of 2 different ablation strategies in patients with paroxysmal and persistent atrial fibrillation","volume":"1","author":"Gaita","year":"2008","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.hrthm.2015.10.006_bib21","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1111\/j.1540-8167.2005.50192.x","article-title":"Left mitral isthmus ablation associated with PV Isolation: long-term results of a prospective randomized study","volume":"16","author":"Fassini","year":"2005","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2015.10.006_bib22","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1161\/CIRCEP.114.001759","article-title":"Efficacy of catheter ablation for persistent atrial fibrillation: a systematic review and meta-analysis of evidence from randomised and non-randomised controlled trials","volume":"7","author":"Wynn","year":"2014","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.hrthm.2015.10.006_bib23","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.ahj.2006.05.029","article-title":"Recurrence of pulmonary vein conduction and atrial fibrillation after pulmonary vein isolation for atrial fibrillation: a randomized trial of the ostial versus the extraostial ablation strategy","volume":"152","author":"Nilsson","year":"2006","journal-title":"Am Heart J"},{"key":"10.1016\/j.hrthm.2015.10.006_bib24","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1016\/j.ijcard.2012.11.072","article-title":"Contact force sensing technology identifies sites of inadequate contact and reduces acute pulmonary vein reconnection: a prospective case control study","volume":"168","author":"Haldar","year":"2013","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.hrthm.2015.10.006_bib25","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1111\/jce.12606","article-title":"Relationship between contact force sensing technology and medium-term outcome of atrial fibrillation ablation: a multicenter study of 600 patients","volume":"26","author":"Jarman","year":"2015","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2015.10.006_bib26","doi-asserted-by":"crossref","first-page":"1812","DOI":"10.1056\/NEJMoa1408288","article-title":"Approaches to catheter ablation for persistent atrial fibrillation","volume":"372","author":"Verma","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2015.10.006_bib27","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1016\/j.hrthm.2010.06.030","article-title":"Evaluation of the left atrial substrate in patients with lone atrial fibrillation using delayed-enhanced MRI: implications for disease progression and response to catheter ablation","volume":"7","author":"Mahnkopf","year":"2010","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2015.10.006_bib28","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1093\/eurheartj\/ehq041","article-title":"Substrate and Trigger Ablation for Reduction of Atrial Fibrillation (STAR AF): a randomized, multicentre, international trial","volume":"31","author":"Verma","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hrthm.2015.10.006_bib29","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/j.hrthm.2012.02.016","article-title":"Improved outcome following restoration of sinus rhythm prior to catheter ablation of persistent atrial fibrillation: a comparative multicenter study","volume":"9","author":"Rivard","year":"2012","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2015.10.006_bib30","doi-asserted-by":"crossref","first-page":"3356","DOI":"10.1093\/eurheartj\/ehu354","article-title":"Recurrence of arrhythmia following short-term oral AMIOdarone after CATheter ablation for atrial fibrillation: a double-blind, randomized, placebo-controlled study (AMIO-CAT trial)","volume":"35","author":"Darkner","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.hrthm.2015.10.006_bib31","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/j.hrthm.2010.01.017","article-title":"Outcomes of long-standing persistent atrial fibrillation ablation: a systematic review","volume":"7","author":"Brooks","year":"2010","journal-title":"Heart Rhythm"}],"container-title":["Heart Rhythm"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527115012473?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527115012473?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,18]],"date-time":"2018-09-18T15:26:40Z","timestamp":1537284400000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1547527115012473"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["S1547527115012473"],"URL":"https:\/\/doi.org\/10.1016\/j.hrthm.2015.10.006","relation":{},"ISSN":["1547-5271"],"issn-type":[{"value":"1547-5271","type":"print"}],"subject":[],"published":{"date-parts":[[2016,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Biatrial linear ablation in sustained nonpermanent AF: Results of the substrate modification with ablation and antiarrhythmic drugs in nonpermanent atrial fibrillation (SMAN-PAF) trial","name":"articletitle","label":"Article Title"},{"value":"Heart Rhythm","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hrthm.2015.10.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}