{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T18:30:13Z","timestamp":1770748213876,"version":"3.49.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["1OT2OD028190"],"award-info":[{"award-number":["1OT2OD028190"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 HL139829"],"award-info":[{"award-number":["R01 HL139829"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R42DA043391"],"award-info":[{"award-number":["R42DA043391"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R56 HL71140"],"award-info":[{"award-number":["R56 HL71140"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["TR002208"],"award-info":[{"award-number":["TR002208"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010249","name":"School of Medicine, Indiana University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010249","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010506","name":"Indiana University Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010506","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","heartrhythmjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart Rhythm"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.hrthm.2019.11.017","type":"journal-article","created":{"date-parts":[[2019,11,19]],"date-time":"2019-11-19T11:53:31Z","timestamp":1574164411000},"page":"544-552","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Skin sympathetic nerve activity and ventricular rate control during atrial fibrillation"],"prefix":"10.1016","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0836-1196","authenticated-orcid":false,"given":"Takashi","family":"Kusayama","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"II","given":"Anthony","family":"Douglas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1314-1673","authenticated-orcid":false,"given":"Juyi","family":"Wan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anisiia","family":"Doytchinova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johnson","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gloria","family":"Mitscher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Straka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4444-0943","authenticated-orcid":false,"given":"Changyu","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4235-3838","authenticated-orcid":false,"suffix":"IV","given":"Thomas H.","family":"Everett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4150-5836","authenticated-orcid":false,"given":"Peng-Sheng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.hrthm.2019.11.017_bib1","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1056\/NEJMoa021328","article-title":"A comparison of rate control and rhythm control in patients with atrial fibrillation","volume":"347","author":"Wyse","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2019.11.017_bib2","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jacc.2014.03.022","article-title":"2014 AHA\/ACC\/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society","volume":"64","author":"January","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2019.11.017_bib3","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1161\/CIRCULATIONAHA.108.776203","article-title":"Neural mechanisms of paroxysmal atrial fibrillation and paroxysmal atrial tachycardia in ambulatory canines","volume":"118","author":"Tan","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2019.11.017_bib4","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1161\/CIRCEP.111.967737","article-title":"Neural control of ventricular rate in ambulatory dogs with pacing-induced sustained atrial fibrillation","volume":"5","author":"Park","year":"2012","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.hrthm.2019.11.017_bib5","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/j.jacep.2018.05.003","article-title":"Effects of vagal nerve stimulation on ganglionated plexi nerve activity and ventricular rate in ambulatory dogs with persistent atrial fibrillation","volume":"4","author":"Jiang","year":"2018","journal-title":"JACC Clin Electrophysiol"},{"key":"10.1016\/j.hrthm.2019.11.017_bib6","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1161\/01.HYP.9.5.429","article-title":"Effects of the cold pressor test on muscle sympathetic nerve activity in humans","volume":"9","author":"Victor","year":"1987","journal-title":"Hypertension"},{"key":"10.1016\/j.hrthm.2019.11.017_bib7","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1113\/jphysiol.2011.223842","article-title":"Augmented single-unit muscle sympathetic nerve activity in heart failure with chronic atrial fibrillation","volume":"590","author":"Ikeda","year":"2012","journal-title":"J Physiol"},{"key":"10.1016\/j.hrthm.2019.11.017_bib8","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3389\/fphys.2014.00111","article-title":"Skin sympathetic nerve activity in humans during exposure to emotionally-charged images: sex differences","volume":"5","author":"Brown","year":"2014","journal-title":"Front Physiol"},{"key":"10.1016\/j.hrthm.2019.11.017_bib9","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1097\/HJH.0b013e3283605c71","article-title":"Muscle and skin sympathetic nerve traffic during physician and nurse blood pressure measurement","volume":"31","author":"Grassi","year":"2013","journal-title":"J Hypertens"},{"key":"10.1016\/j.hrthm.2019.11.017_bib10","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/BF02514624","article-title":"Cutaneous distribution of sympathetic postganglionic fibers from stellate ganglion: a retrograde axonal tracing study using wheat germ agglutinin conjugated with horseradish peroxidase","volume":"8","author":"Taniguchi","year":"1994","journal-title":"J Anesth"},{"key":"10.1016\/j.hrthm.2019.11.017_bib11","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1016\/j.hrthm.2015.02.012","article-title":"Using skin sympathetic nerve activity to estimate stellate ganglion nerve activity in dogs","volume":"12","author":"Jiang","year":"2015","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2019.11.017_bib12","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1111\/jce.12508","article-title":"Estimating sympathetic tone by recording subcutaneous nerve activity in ambulatory dogs","volume":"26","author":"Robinson","year":"2015","journal-title":"J Cardiovasc Electrophysiol"},{"key":"10.1016\/j.hrthm.2019.11.017_bib13","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.hrthm.2016.09.019","article-title":"Simultaneous noninvasive recording of skin sympathetic nerve activity and electrocardiogram","volume":"14","author":"Doytchinova","year":"2017","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2019.11.017_bib14","doi-asserted-by":"crossref","first-page":"3201","DOI":"10.1016\/j.jacc.2017.10.065","article-title":"Crescendo skin sympathetic nerve activity and ventricular arrhythmia","volume":"70","author":"Kabir","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2019.11.017_bib15","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/j.hrthm.2017.03.030","article-title":"Skin sympathetic nerve activity precedes the onset and termination of paroxysmal atrial tachycardia and fibrillation","volume":"14","author":"Uradu","year":"2017","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2019.11.017_bib16","doi-asserted-by":"crossref","first-page":"e125853","DOI":"10.1172\/jci.insight.125853","article-title":"Skin sympathetic nerve activity and the temporal clustering of cardiac arrhythmias","volume":"4","author":"Kusayama","year":"2019","journal-title":"JCI Insight"},{"key":"10.1016\/j.hrthm.2019.11.017_bib17","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/0002-9149(90)90942-T","article-title":"Circadian fluctuations in ventricular response to atrial fibrillation","volume":"66","author":"Raeder","year":"1990","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.hrthm.2019.11.017_bib18","first-page":"H1643","article-title":"Autonomic modulation of ventricular rate in atrial fibrillation","volume":"272","author":"Nagayoshi","year":"1997","journal-title":"Am J Physiol"},{"key":"10.1016\/j.hrthm.2019.11.017_bib19","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.hrthm.2015.11.031","article-title":"Intermittent left cervical vagal nerve stimulation damages the stellate ganglia and reduces ventricular rate during sustained atrial fibrillation in ambulatory dogs","volume":"13","author":"Chinda","year":"2016","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2019.11.017_bib20","doi-asserted-by":"crossref","first-page":"H1031","DOI":"10.1152\/ajpheart.00703.2016","article-title":"Recording sympathetic nerve activity in conscious humans and other mammals: guidelines and the road to standardization","volume":"312","author":"Hart","year":"2017","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.hrthm.2019.11.017_bib21","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0006-3495(64)86768-0","article-title":"Random walk models for the spike activity of a single neuron","volume":"4","author":"Gerstein","year":"1964","journal-title":"Biophys J"},{"key":"10.1016\/j.hrthm.2019.11.017_bib22","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1523\/JNEUROSCI.19-02-00599.1999","article-title":"Subthalamic nucleus neurons switch from single-spike activity to burst-firing mode","volume":"19","author":"Beurrier","year":"1999","journal-title":"J Neurosci"},{"key":"10.1016\/j.hrthm.2019.11.017_bib23","doi-asserted-by":"crossref","first-page":"M1","DOI":"10.1093\/geronj\/46.1.M1","article-title":"Age-related changes of sympathetic outflow to muscles in humans","volume":"46","author":"Iwase","year":"1991","journal-title":"J Gerontol"},{"key":"10.1016\/j.hrthm.2019.11.017_bib24","doi-asserted-by":"crossref","first-page":"R877","DOI":"10.1152\/ajpregu.00290.2013","article-title":"Nonuniform, age-related decrements in regional sweating and skin blood flow","volume":"305","author":"Smith","year":"2013","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.hrthm.2019.11.017_bib25","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1152\/japplphysiol.00730.2016","article-title":"Blunted increases in skin sympathetic nerve activity are related to attenuated reflex vasodilation in aged human skin","volume":"121","author":"Stanhewicz","year":"2016","journal-title":"J Appl Physiol (1985)"},{"key":"10.1016\/j.hrthm.2019.11.017_bib26","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.1111\/j.1540-8159.1998.tb01200.x","article-title":"Age and gender influences on rate and duration of paroxysmal atrial fibrillation","volume":"21","author":"Hnatkova","year":"1998","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.hrthm.2019.11.017_bib27","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.yjmcc.2016.03.011","article-title":"Prolongation of atrio-ventricular node conduction in a rabbit model of ischaemic cardiomyopathy: role of fibrosis and connexin remodelling","volume":"94","author":"Nisbet","year":"2016","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.hrthm.2019.11.017_bib28","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1093\/eurheartj\/15.suppl_A.9","article-title":"Paroxysmal atrial fibrillation: a disorder of autonomic tone?","volume":"15","author":"Coumel","year":"1994","journal-title":"Eur Heart J"}],"container-title":["Heart Rhythm"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S154752711931029X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S154752711931029X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T06:50:07Z","timestamp":1761547807000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S154752711931029X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":28,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["S154752711931029X"],"URL":"https:\/\/doi.org\/10.1016\/j.hrthm.2019.11.017","relation":{},"ISSN":["1547-5271"],"issn-type":[{"value":"1547-5271","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Skin sympathetic nerve activity and ventricular rate control during atrial fibrillation","name":"articletitle","label":"Article Title"},{"value":"Heart Rhythm","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hrthm.2019.11.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Heart Rhythm Society. All rights reserved.","name":"copyright","label":"Copyright"}]}}