{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T14:42:36Z","timestamp":1791988956425,"version":"4.4.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007330","name":"AtriCure","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007330","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008497","name":"Boston Scientific","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007330","name":"AtriCure","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007330","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004326","name":"Bayer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004326","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004336","name":"Novartis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004336","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011725","name":"Servier","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011725","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Elekta"},{"DOI":"10.13039\/100004334","name":"Merck","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004334","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007210","name":"Varian Medical Systems","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007210","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004755","name":"EMD Serono","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004755","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007210","name":"Varian","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007210","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007210","name":"Varian Medical Systems","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007210","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","heartrhythmjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Heart Rhythm"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1016\/j.hrthm.2020.03.013","type":"journal-article","created":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T12:36:26Z","timestamp":1584707786000},"page":"1381-1392","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":121,"title":["Cardiac radioablation\u2014A systematic review"],"prefix":"10.1016","volume":"17","author":[{"given":"Martijn H.","family":"van der Ree","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Blanck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Limpens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlie H.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian V.","family":"Balgobind","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edith M.T.","family":"Dieleman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur A.M.","family":"Wilde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul C.","family":"Zei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joris R.","family":"de Groot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben J.","family":"Slotman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillip S.","family":"Cuculich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clifford G.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter G.","family":"Postema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.hrthm.2020.03.013_bib1","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.116.004357","article-title":"Multicenter experience with catheter ablation for ventricular tachycardia in lamin A\/C cardiomyopathy","volume":"9","author":"Kumar","year":"2016","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.hrthm.2020.03.013_bib2","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1056\/NEJMoa1613773","article-title":"Noninvasive cardiac radiation for ablation of ventricular tachycardia","volume":"377","author":"Cuculich","year":"2017","journal-title":"N Engl J Med"},{"key":"10.1016\/j.hrthm.2020.03.013_bib3","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1161\/CIRCULATIONAHA.118.038261","article-title":"Phase I\/II trial of electrophysiology-guided noninvasive cardiac radioablation for ventricular tachycardia","volume":"139","author":"Robinson","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.hrthm.2020.03.013_bib4","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1093\/europace\/euz133","article-title":"Stereotactic radiosurgery for ablation of ventricular tachycardia","volume":"21","author":"Neuwirth","year":"2019","journal-title":"Europace"},{"key":"10.1016\/j.hrthm.2020.03.013_bib5","article-title":"Cardiac radiosurgery for malignant ventricular tachycardia","volume":"6","author":"Cvek","year":"2014","journal-title":"Cureus"},{"key":"10.1016\/j.hrthm.2020.03.013_bib6","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1161\/CIRCEP.115.002765","article-title":"Stereotactic ablative radiotherapy for the treatment of refractory cardiac ventricular arrhythmia","volume":"8","author":"Loo","year":"2015","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.hrthm.2020.03.013_bib7","doi-asserted-by":"crossref","first-page":"b2535","DOI":"10.1136\/bmj.b2535","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"339","author":"Moher","year":"2009","journal-title":"BMJ"},{"key":"10.1016\/j.hrthm.2020.03.013_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001419","article-title":"PRISMA for Abstracts Group. PRISMA for Abstracts: reporting systematic reviews in journal and conference abstracts","volume":"10","author":"Beller","year":"2013","journal-title":"PLoS Med"},{"key":"10.1016\/j.hrthm.2020.03.013_bib9","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1186\/s13643-016-0384-4","article-title":"Rayyan\u2014a web and mobile app for systematic reviews","volume":"5","author":"Ouzzani","year":"2016","journal-title":"Syst Rev"},{"key":"10.1016\/j.hrthm.2020.03.013_bib10","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/1471-2288-14-43","article-title":"SYRCLE\u2019s risk of bias tool for animal studies","volume":"14","author":"Hooijmans","year":"2014","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.hrthm.2020.03.013_bib11","doi-asserted-by":"crossref","first-page":"i4919","DOI":"10.1136\/bmj.i4919","article-title":"ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions","volume":"355","author":"Sterne","year":"2016","journal-title":"BMJ"},{"key":"10.1016\/j.hrthm.2020.03.013_bib12","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1136\/bmjebm-2017-110853","article-title":"Methodological quality and synthesis of case series and case reports","volume":"23","author":"Murad","year":"2018","journal-title":"BMJ Evid Based Med"},{"key":"10.1016\/j.hrthm.2020.03.013_bib13","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.cardiores.2006.09.010","article-title":"Heavy ion radiation up-regulates Cx43 and ameliorates arrhythmogenic substrates in hearts after myocardial infarction","volume":"72","author":"Amino","year":"2006","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.hrthm.2020.03.013_bib14","doi-asserted-by":"crossref","first-page":"H1014","DOI":"10.1152\/ajpheart.00160.2009","article-title":"Year-long upregulation of connexin43 in rabbit hearts by heavy ion irradiation","volume":"298","author":"Amino","year":"2010","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.hrthm.2020.03.013_bib15","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/j.hrthm.2010.02.010","article-title":"Noninvasive stereotactic radiosurgery (CyberHeart) for creation of ablation lesions in the atrium","volume":"7","author":"Sharma","year":"2010","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2020.03.013_bib16","doi-asserted-by":"crossref","first-page":"3745","DOI":"10.1120\/jacmp.v13i3.3745","article-title":"In\u00a0vivo dose measurement using TLDs and MOSFET dosimeters for cardiac radiosurgery","volume":"13","author":"Gardner","year":"2012","journal-title":"J Appl Clin Med Phys"},{"key":"10.1016\/j.hrthm.2020.03.013_bib17","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.ijrobp.2014.02.036","article-title":"Dose-escalation study for cardiac radiosurgery in a porcine model","volume":"89","author":"Blanck","year":"2014","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.hrthm.2020.03.013_bib18","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1161\/CIRCEP.114.002436","article-title":"Atrioventricular node ablation in Langendorff-perfused porcine hearts using carbon ion particle therapy: methods and an in\u00a0vivo feasibility investigation for catheter-free ablation of cardiac arrhythmias","volume":"8","author":"Lehmann","year":"2015","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"10.1016\/j.hrthm.2020.03.013_bib19","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1515\/bmt-2014-0101","article-title":"Treatment of arrhythmias by external charged particle beams: a Langendorff feasibility study","volume":"60","author":"Prall","year":"2015","journal-title":"Biomed Tech (Berl)"},{"key":"10.1016\/j.hrthm.2020.03.013_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep38895","article-title":"Feasibility study on cardiac arrhythmia ablation using high-energy heavy ion beams","volume":"6","author":"Lehmann","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.hrthm.2020.03.013_bib21","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1111\/pace.13031","article-title":"Inducibility of ventricular arrhythmia 1 year following treatment with heavy ion irradiation in dogs with myocardial infarction","volume":"40","author":"Amino","year":"2017","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.hrthm.2020.03.013_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1161\/CIRCEP.116.004304","article-title":"External arrhythmia ablation using photon beams","volume":"10","author":"Lehmann","year":"2017","journal-title":"Circ Arrhythmia Electrophysiol"},{"key":"10.1016\/j.hrthm.2020.03.013_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1161\/JAHA.117.007193","article-title":"Swine atrioventricular node ablation using stereotactic radiosurgery: methods and in\u00a0vivo feasibility investigation for catheter-free ablation of cardiac arrhythmias","volume":"6","author":"Refaat","year":"2017","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.hrthm.2020.03.013_bib24","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1016\/j.hrthm.2018.04.015","article-title":"Safety and efficacy of stereotactic radioablation targeting pulmonary vein tissues in an experimental model","volume":"15","author":"Zei","year":"2018","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2020.03.013_bib25","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.1016\/j.hrthm.2019.04.030","article-title":"Left ventricular function after noninvasive cardiac ablation using proton beam therapy in a porcine model","volume":"16","author":"Hohmann","year":"2019","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.hrthm.2020.03.013_bib26","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1093\/europace\/euu406","article-title":"Pulmonary vein isolation by radiosurgery: implications for non-invasive treatment of atrial fibrillation","volume":"17","author":"Bode","year":"2015","journal-title":"Europace"},{"key":"10.1016\/j.hrthm.2020.03.013_bib27","doi-asserted-by":"crossref","first-page":"5000","DOI":"10.1038\/s41598-019-41314-x","article-title":"Biological cardiac tissue effects of high-energy heavy ions\u2014investigation for myocardial ablation","volume":"9","author":"Rapp","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.hrthm.2020.03.013_bib28","first-page":"e738","article-title":"Late gadolinium enhancement cardiac magnetic resonance imaging post-robotic radiosurgical pulmonary vein isolation (RRPVI): first case in the world","volume":"8","author":"Monroy","year":"2016","journal-title":"Cureus"},{"key":"10.1016\/j.hrthm.2020.03.013_bib29","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.radonc.2018.04.025","article-title":"Rescue procedure for an electrical storm using robotic non-invasive cardiac radio-ablation","volume":"128","author":"Jumeau","year":"2018","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.hrthm.2020.03.013_bib30","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.hrcr.2018.10.007","article-title":"Stereotactic radiosurgery as a treatment for recurrent ventricular tachycardia associated with cardiac fibroma","volume":"5","author":"Haskova","year":"2019","journal-title":"HeartRhythm Case Rep"},{"key":"10.1016\/j.hrthm.2020.03.013_bib31","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.hrcr.2019.03.004","article-title":"Risen from the dead: cardiac stereotactic ablative radiotherapy as last rescue in a patient with refractory ventricular fibrillation storm","volume":"5","author":"Scholz","year":"2019","journal-title":"HeartRhythm Case Rep"},{"key":"10.1016\/j.hrthm.2020.03.013_bib32","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1111\/pace.13731","article-title":"Stereotactic body radiation therapy for refractory ventricular tachycardia secondary to cardiac lipoma: a case report","volume":"42","author":"Zeng","year":"2019","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.hrthm.2020.03.013_bib33","first-page":"97","article-title":"Noninvasive ablation of ventricular tachycardia with stereotactic radiotherapy in a patient with arrhythmogenic right ventricular cardiomyopathy","volume":"73","author":"Mart\u00ed-Almor","year":"2020","journal-title":"Rev Esp Cardiol (Engl Ed)"},{"key":"10.1016\/j.hrthm.2020.03.013_bib34","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1001\/jama.291.8.974","article-title":"Different patterns of duplicate publication: an analysis of articles used in systematic reviews","volume":"291","author":"von Elm","year":"2004","journal-title":"JAMA"},{"key":"10.1016\/j.hrthm.2020.03.013_bib35","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0166733","article-title":"The devil is in the details: incomplete reporting in preclinical animal research","volume":"11","author":"Avey","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.hrthm.2020.03.013_bib36","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.yjmcc.2013.10.018","article-title":"Cardiac fibrosis and arrhythmogenesis: the road to repair is paved with perils","volume":"70","author":"Nguyen","year":"2014","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.hrthm.2020.03.013_bib37","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/0735-1097(91)90760-7","article-title":"Macroreentry in the infarcted human heart: the mechanism of ventricular tachycardias with a \u201cfocal\u201d activation pattern","volume":"18","author":"de Bakker","year":"1991","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.hrthm.2020.03.013_bib38","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1007\/s00441-016-2431-9","article-title":"Cardiac fibrosis in myocardial infarction\u2014from repair and remodeling to regeneration","volume":"365","author":"Talman","year":"2016","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.hrthm.2020.03.013_bib39","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.ijrobp.2019.08.032","article-title":"Longer term results from a phase I\/II study of EP-guided Noninvasive Cardiac Radioablation for Treatment of Ventricular Tachycardia (ENCORE-VT)","volume":"105","author":"Robinson","year":"2019","journal-title":"Int J Radiat Oncol"},{"key":"10.1016\/j.hrthm.2020.03.013_bib40","first-page":"323","article-title":"2019 HRS\/EHRA\/APHRS\/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias","volume":"35","author":"Cronin","year":"2019","journal-title":"Heart Rhythm"}],"container-title":["Heart Rhythm"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527120302538?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1547527120302538?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T06:51:01Z","timestamp":1761547861000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1547527120302538"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":40,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["S1547527120302538"],"URL":"https:\/\/doi.org\/10.1016\/j.hrthm.2020.03.013","relation":{},"ISSN":["1547-5271"],"issn-type":[{"value":"1547-5271","type":"print"}],"subject":[],"published":{"date-parts":[[2020,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cardiac radioablation\u2014A systematic review","name":"articletitle","label":"Article Title"},{"value":"Heart Rhythm","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hrthm.2020.03.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Heart Rhythm Society. All rights reserved.","name":"copyright","label":"Copyright"}]}}